Research Topics
| Annie HussonSummaryCountry: France Publications
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Detail Information
Publications
Argininosuccinate synthetase from the urea cycle to the citrulline-NO cycleAnnie Husson
Aden, Institut Fédératif de Recherches Multidisciplinaires sur les Peptides no 23 IFRMP 23, Rouen, France
Eur J Biochem 270:1887-99. 2003..In most cases, regulation of ASS gene expression is exerted at a transcriptional level, but molecular mechanisms are still poorly understood...
IL-1beta stimulates argininosuccinate synthetase gene expression through NF-kappaB in Caco-2 cellsCarole Brasse-Lagnel
Groupe Appareil Digestif, Environnement et Nutrition, EA 3234, , , Rouen, France
Biochimie 87:403-9. 2005..Using gel shift assay and double-strand oligonucleotide sequence of the identified putative NF-kappaB binding site of the ASS promoter, we provide evidence that NF-kappaB may functionally interact with this element...
Glutamine induces nuclear degradation of the NF-κB p65 subunit in Caco-2/TC7 cellsCéline Lesueur
EA NeoVasc 4309, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Rouen Institute for Biomedical Research, European Institute for Peptide Research IFRMP 23, University of Rouen, Rouen, France
Biochimie 94:806-15. 2012..We also demonstrate that p38 MAPK lies between glutamine and the NF-κB pathway. In conclusion, this study identified for the first time the signaling pathway by which glutamine may protect against inflammatory conditions...
Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cellsCarole Brasse-Lagnel
Groupe Appareil Digestif, Environnement et Nutrition, Institut Federatif de Recherches Multidisciplinaires sur les Peptides, Universite de Rouen, 76183 Rouen Cedex, France
J Biol Chem 278:52504-10. 2003..Collectively, the results constitute the first demonstration of a functional relationship between a regulating signal (glutamine), a transcription factor (Sp1), and the transcription of the ASS gene...
Biphasic effect of IL-1beta on the activity of argininosuccinate synthetase in Caco-2 cells. Involvement of nitric oxide productionCarole Brasse-Lagnel
Groupe Appareil Digestif, Environnement et Nutrition, Institut Federatif de Recherches Multidisciplinaires sur les Peptides, Faculté de Médecine Pharmacie de Rouen, 22, boulevard Gambetta, 76183 Rouen Cedex, Universite de Rouen, France
Biochimie 88:607-12. 2006..Finally, such an inhibiting effect of NO on ASS activity may be related, at least in part, to S-nitrosylation of the protein. The physiological relevance of the antagonistic effects of IL-1beta and NO on ASS is discussed...
Glutamine and interleukin-1beta interact at the level of Sp1 and nuclear factor-kappaB to regulate argininosuccinate synthetase gene expressionCarole Brasse Lagnel
Groupe Appareil Digestif, Environnement et Nutrition, Institut Fédératif de Recherches Multidisciplinaires sur Peptides, Universite de Rouen, France
FEBS J 274:5250-62. 2007....
