Thomas Walter

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. doi request reprint Endoscopic or percutaneous biliary drainage for Klatskin tumors?
    Thomas Walter
    Division of Medical Oncology, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada
    J Vasc Interv Radiol 24:113-21. 2013
  2. doi request reprint Is the combination of chromogranin A and pancreatic polypeptide serum determinations of interest in the diagnosis and follow-up of gastro-entero-pancreatic neuroendocrine tumours?
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Eur J Cancer 48:1766-73. 2012
  3. doi request reprint Major hyperghrelinemia in advanced well-differentiated neuroendocrine carcinomas: report of three cases
    Thomas Walter
    Hospices Civils de Lyon, Pavillon H, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Eur J Endocrinol 161:639-45. 2009
  4. doi request reprint Well-differentiated endocrine carcinoma of the renal pelvis: report of a case with sustained objective response to octreotide
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Pathol Res Pract 205:183-7. 2009
  5. doi request reprint Evaluation of the combination 5-fluorouracil, dacarbazine, and epirubicin in patients with advanced well-differentiated neuroendocrine tumors
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    Clin Colorectal Cancer 9:248-54. 2010
  6. doi request reprint Effects of somatostatin and octreotide on the interactions between neoplastic gastroenteropancreatic endocrine cells and endothelial cells: a comparison between in vitro and in vivo properties
    Thomas Walter
    Lyon Cancer Research Center, Team 4, INSERM UMR1052 CNRS UMR5286, Lyon, France
    Neuroendocrinology 94:200-8. 2011
  7. doi request reprint Angiogenesis and tumor progression in neuroendocrine digestive tumors
    Gilles Poncet
    INSERM, U865, IFR Lyon Est, Universite Claude Bernard Lyon 1, Faculte Laennec, Lyon, France
    J Surg Res 154:68-77. 2009
  8. doi request reprint Contrast-enhanced ultrasound after devascularisation of neuroendocrine liver metastases: functional and morphological evaluation
    Aymeric Guibal
    Hospices Civils de Lyon, Hopital Edouard Herriot, Service d Imagerie Digestive, 69437 Lyon Cedex 03, France
    Eur Radiol 23:805-15. 2013
  9. doi request reprint Neuroendocrine tumors of Meckel's diverticulum: lessons from a single institution study of eight cases
    Gilles Poncet
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    J Gastrointest Surg 15:101-9. 2011
  10. doi request reprint Primary neuroendocrine tumors of the main pancreatic duct: a rare entity
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    Virchows Arch 458:537-46. 2011

Collaborators

Detail Information

Publications32

  1. doi request reprint Endoscopic or percutaneous biliary drainage for Klatskin tumors?
    Thomas Walter
    Division of Medical Oncology, University of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada
    J Vasc Interv Radiol 24:113-21. 2013
    ..This study compared outcomes of endoscopic biliary drainage (EBD) and percutaneous transhepatic biliary drainage (PTBD)...
  2. doi request reprint Is the combination of chromogranin A and pancreatic polypeptide serum determinations of interest in the diagnosis and follow-up of gastro-entero-pancreatic neuroendocrine tumours?
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Eur J Cancer 48:1766-73. 2012
    ..Combining serum CgA and pancreatic polypeptide (PP) levels may increase the sensitivity of tumour markers in the diagnosis of GEPNET...
  3. doi request reprint Major hyperghrelinemia in advanced well-differentiated neuroendocrine carcinomas: report of three cases
    Thomas Walter
    Hospices Civils de Lyon, Pavillon H, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Eur J Endocrinol 161:639-45. 2009
    ..We aimed to gain insight into the functional consequences of ghrelin overproduction in patients with neuroendocrine tumors and its relations with disease characteristics and evolution...
  4. doi request reprint Well-differentiated endocrine carcinoma of the renal pelvis: report of a case with sustained objective response to octreotide
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Pathol Res Pract 205:183-7. 2009
    ....
  5. doi request reprint Evaluation of the combination 5-fluorouracil, dacarbazine, and epirubicin in patients with advanced well-differentiated neuroendocrine tumors
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    Clin Colorectal Cancer 9:248-54. 2010
    ..The aim of this study was to retrospectively analyze the efficacy and safety of the combination of 5-fluorouracil (5-FU), dacarbazine, and epirubicin (FDE) in 39 patients with advanced, well-differentiated neuroendocrine tumors (NETs)...
  6. doi request reprint Effects of somatostatin and octreotide on the interactions between neoplastic gastroenteropancreatic endocrine cells and endothelial cells: a comparison between in vitro and in vivo properties
    Thomas Walter
    Lyon Cancer Research Center, Team 4, INSERM UMR1052 CNRS UMR5286, Lyon, France
    Neuroendocrinology 94:200-8. 2011
    ..Experimental studies in vitro suggest that somatostatin and some of its analogues used in clinical practice, such as octreotide, may have potent antiangiogenic properties. However, the clinical transposition of these data is difficult...
  7. doi request reprint Angiogenesis and tumor progression in neuroendocrine digestive tumors
    Gilles Poncet
    INSERM, U865, IFR Lyon Est, Universite Claude Bernard Lyon 1, Faculte Laennec, Lyon, France
    J Surg Res 154:68-77. 2009
    ..We used an experimental orthotopic xenograft model to analyze the relations between angiogenic activity and tumor progression in this tumor subset...
  8. doi request reprint Contrast-enhanced ultrasound after devascularisation of neuroendocrine liver metastases: functional and morphological evaluation
    Aymeric Guibal
    Hospices Civils de Lyon, Hopital Edouard Herriot, Service d Imagerie Digestive, 69437 Lyon Cedex 03, France
    Eur Radiol 23:805-15. 2013
    ....
  9. doi request reprint Neuroendocrine tumors of Meckel's diverticulum: lessons from a single institution study of eight cases
    Gilles Poncet
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    J Gastrointest Surg 15:101-9. 2011
    ..Endocrine tumors of Meckel's diverticulum are rare. Their clinical and pathological characteristics are not well known, making it difficult to assess the best strategy for therapeutic management...
  10. doi request reprint Primary neuroendocrine tumors of the main pancreatic duct: a rare entity
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Lyon, France
    Virchows Arch 458:537-46. 2011
    ..In conclusion, despite their rarity, primary neuroendocrine tumors of the main pancreatic duct deserve recognition and must be considered in the etiological diagnosis of ductal stenosis...
  11. doi request reprint Neuroendocrine neoplasms of the jejunum: a heterogeneous group with distinctive proximal and distal subsets
    Xavier Chopin-Laly
    Service de Chirurgie Digestive, Hospices Civils de Lyon, Hopital Edouard Herriot, 69437, Lyon Cedex 03, France
    Virchows Arch 462:489-99. 2013
    ..Our data suggest that the arbitrary limit between upper and lower jejunal tumors might be fixed at 50 cm from the duodenojejunal ligament...
  12. doi request reprint Outcome of patients receiving chemotherapy for advanced biliary tract or gallbladder carcinoma
    Philippe A Cassier
    Department of Medical Oncology, Hopital Edouard Herriot, Hospices Civils de Lyon, Lyon, France
    Eur J Gastroenterol Hepatol 22:1111-7. 2010
    ..Currently, there is no standard chemotherapy for this disease, but several single agents and combinations have shown promising activity, most notably gemcitabine-based combinations...
  13. doi request reprint Complete response of hepatocellular carcinoma with systemic combination chemotherapy: not to get out the chemotherapy?
    Gilles Boschetti
    Fédération des spécialités digestives, Universite Claude Bernard Lyon 1, Villeurbanne, France
    Eur J Gastroenterol Hepatol 22:1015-8. 2010
    ..Our report shows that another important challenge remains in the identification of predictive factors of response to standard chemotherapy or molecular targeted agents...
  14. doi request reprint Long-term antiviral therapy for recurrent hepatitis C after liver transplantation in nonresponders: biochemical, virological, and histological impact
    Thomas Walter
    Unite de Transplantation Hepatique, Fédération des spécialités digestives, Hopital Edouard Herriot, France
    Liver Transpl 15:54-63. 2009
    ..Our results show the feasibility, safety, and efficacy of long-term antiviral therapy in nonresponder patients with a recurrent posttransplant hepatitis C virus infection...
  15. doi request reprint Primary malignant solid pseudopapillary tumors of the gastroduodenal area
    Thomas Walter
    Fédération des spécialités digestives, Hospices Civils de Lyon, Hopital Edouard Herriot, Lyon Cedex 03, France
    Clin Res Hepatol Gastroenterol 35:227-33. 2011
    ..In conclusion, we report two unusual cases of extrapancreatic SPT arising in the gastroduodenal area, associated with a malignant course and an extensive metastatic dissemination...
  16. pmc Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth
    Christophe Couderc
    INSERM, U865, Faculte Laennec, Universite Claude Bernard Lyon 1, Lyon, France
    Am J Pathol 178:336-44. 2011
    ..Interestingly, a more potent antitumor efficiency could be obtained by simultaneously targeting several levels of the PI3K/mTOR pathway...
  17. doi request reprint Evaluation of shearwave elastography for the characterisation of focal liver lesions on ultrasound
    Aymeric Guibal
    Service d Imagerie abdominale, Hospices Civils de Lyon, Hopital Edouard Herriot, 69437, Lyon Cedex 03, France
    Eur Radiol 23:1138-49. 2013
    ..To determine the elasticity characteristics of focal liver lesions (FLLs) by shearwave elastography (SWE)...
  18. doi request reprint Gemcitabine and oxaliplatin combination chemotherapy for metastatic well-differentiated neuroendocrine carcinomas: a single-center experience
    Philippe A Cassier
    Multidisciplinary Medical Oncology Day Unit, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
    Cancer 115:3392-9. 2009
    ..The authors assessed the efficacy of gemcitabine-oxaliplatin combination (GEMOX) in the treatment of patients with metastatic neuroendocrine tumors...
  19. doi request reprint Antitumor effect of everolimus in preclinical models of high-grade gastroenteropancreatic neuroendocrine carcinomas
    Julien Bollard
    Endocrine Differentiation and Tumorigenesis Laboratory, Centre de Recherche en Cancérologie de Lyon, INSERM U1052 CNRS UMR5286, Universite de Lyon, Faculte Laennec, Lyon, France
    Neuroendocrinology 97:331-40. 2013
    ..Since PDNECs have been shown to strongly express mTOR pathway components, the aim of the present study was to assess the antitumor effect of the mTOR inhibitor everolimus in preclinical models of PDNECs...
  20. doi request reprint A SDHB malignant paraganglioma with dramatic response to temozolomide-capecitabine
    Cécile Nozières
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Place d Arsonval, Lyon Cedex 03, France
    Eur J Endocrinol 166:1107-11. 2012
    ..This observation points to a possible genotype response to treatment relationships, which could help to design tailor-made treatments in the future...
  21. doi request reprint 18F-FLT and 18F-FDG positron emission tomography for the imaging of advanced well-differentiated gastro-entero-pancreatic endocrine tumours
    Francesco Giammarile
    Nuclear Medicine Department, Hospices Civils de Lyon, Lyon Sud Hospital, France
    Nucl Med Commun 32:91-7. 2011
    ..At present, there are no studies investigating its role in GEP. The aim of this prospective study was to assess the value of 18F-FLT-PET for the evaluation of GEP...
  22. doi request reprint Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis
    Anne M Horgan
    Princess Margaret Hospital, Toronto, Ontario, Canada
    J Clin Oncol 30:1934-40. 2012
    ..The benefit of adjuvant therapy (AT) for biliary tract cancer (BTC) is unclear, with conflicting results from nonrandomized studies. We report a systematic review and meta-analysis to determine the impact of AT on survival...
  23. doi request reprint Ursodeoxycholic acid with vitamin E in patients with nonalcoholic steatohepatitis: long-term results
    Florence Pietu
    Hospices civils de Lyon pavillon H, Hopital Edouard Herriot, Fédération des spécialités digestives, 69437 Lyon Cedex 03, France
    Clin Res Hepatol Gastroenterol 36:146-55. 2012
    ..The objective of this study was to report the long-term tolerability and efficacy of this combination in our ten-year single center experience...
  24. doi request reprint Feasibility and benefits of second-line chemotherapy in advanced biliary tract cancer: a large retrospective study
    Thomas Walter
    Princess Margaret Hospital, Toronto, Ontario, Canada
    Eur J Cancer 49:329-35. 2013
    ..First-line chemotherapy (CT1) is effective in advanced biliary tract cancer (ABTC). The benefits of second-line chemotherapy (CT2) are unclear...
  25. doi request reprint Correlation and agreement between contrast-enhanced ultrasonography and perfusion computed tomography for assessment of liver metastases from endocrine tumors: normalization enhances correlation
    Thibaud Lefort
    Abdominal Imaging Unit, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
    Ultrasound Med Biol 38:953-61. 2012
    ..26 (-0.79; 1.31) for blood volume and +0.21 (-0.46; 0.87) for mean transit time. We conclude that normalization markedly increased correlation between CEUS- and CT-derived perfusion values and allowed agreement assessment...
  26. doi request reprint Biopsy specimens obtained with small-caliber endoscopes have comparable diagnostic performances than those obtained with conventional endoscopes: a prospective study on 1335 specimens
    Thomas Walter
    Hospices Civils de Lyon, Hopital Edouard Herriot, Fédération des spécialités digestives, Villeurbanne, France
    J Clin Gastroenterol 44:12-7. 2010
    ..The aim of this study was to evaluate the adequacy of biopsy specimens obtained with small forceps for histologic diagnosis...
  27. pmc Recent trends in the treatment of well-differentiated endocrine carcinoma of the small bowel
    Gilles Poncet
    Department of Digestive Surgery, Edouard Herriot Hospital, 69437 Lyon Cedex 03, France
    World J Gastroenterol 16:1696-706. 2010
    ..Finally, it has to be emphasized that it is of the utmost importance to enroll these patients with a rare disease in prospective clinical trials assessing new therapeutic strategies...
  28. doi request reprint Quality of clinical trials in gastroenteropancreatic neuroendocrine tumours
    Thomas Walter
    Department of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto, ON, Canada
    Neuroendocrinology 96:238-48. 2012
    ..Our aim was to review the quality of treatment trials in NETs in order to inform the design and reporting of future studies...
  29. doi request reprint New treatment strategies in advanced neuroendocrine tumours
    Thomas Walter
    Fédération des spécialités digestives, Hopital Edouard Herriot, Lyon Cedex 03, France
    Dig Liver Dis 44:95-105. 2012
    ..Finally, peptide receptor radionuclide therapy has shown promising activity in non-comparative studies in advanced neuroendocrine tumours...
  30. ncbi request reprint TIPS thrombosis related to abdominal trauma
    Florence Pietu
    Department of Digestive Diseases, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
    Eur J Gastroenterol Hepatol 22:883-5. 2010
    ..Biological screening identified an inherited protein C deficiency, which supports a recent notion that portal vein thrombosis most often occurs when both the local and the systemic aetiological factors are combined...
  31. ncbi request reprint The role of angiogenesis in endocrine liver metastases: an experimental study
    Celine Pourreyron
    INSERM, U865, Faculte Laennec, Universite Claude Bernard Lyon 1, Lyon, France
    J Surg Res 144:64-73. 2008
    ..4 +/- 5.6% versus 18.3 +/- 3.4). Our results suggest that active angiogenesis is not necessary for the engraftment and early growth of endocrine cells metastatic to the liver but is required at a later stage of progression...
  32. ncbi request reprint Factors influencing the progression of fibrosis in patients with recurrent hepatitis C after liver transplantation under antiviral therapy: a retrospective analysis of 939 liver biopsies in a single center
    Thomas Walter
    Unité de transplantation hépatique Fédération des Spécialités Digestives, Hopital Edouard Herriot, Lyon, France
    Liver Transpl 13:294-301. 2007
    ....