S Vukusic

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. ncbi request reprint Natural history of multiple sclerosis: a unifying concept
    Christian Confavreux
    Service de Neurologie A, the European Database for Multiple Sclerosis EDMUS Coordinating Center and INSERM U 433, Hopital Neurologique, Lyon, France
    Brain 129:606-16. 2006
  2. doi request reprint [Prevention of multiple sclerosis: a realistic goal?]
    S Vukusic
    Service de Neurologie A et Fondation Eugène Devic EDMUS pour la Sclérose en Plaques, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyon Bron Cedex, France
    Rev Neurol (Paris) 168:836-45. 2012
  3. ncbi request reprint Pregnancy and multiple sclerosis: the children of PRIMS
    Sandra Vukusic
    The European Database for Multiple Sclerosis Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Clin Neurol Neurosurg 108:266-70. 2006
  4. ncbi request reprint [Multiple sclerosis and pregnancy]
    S Vukusic
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59, boulevard Pinel, 69677 Bron Cedex
    Rev Neurol (Paris) 162:299-309. 2006
  5. ncbi request reprint Prognostic factors for progression of disability in the secondary progressive phase of multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyon Cedex 03, 69394, France
    J Neurol Sci 206:135-7. 2003
  6. ncbi request reprint Primary and secondary progressive multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyons Cedex 03, 69394, France
    J Neurol Sci 206:153-5. 2003
  7. pmc Regional variations in the prevalence of multiple sclerosis in French farmers
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    J Neurol Neurosurg Psychiatry 78:707-9. 2007
  8. ncbi request reprint Natural history of multiple sclerosis: risk factors and prognostic indicators
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    Curr Opin Neurol 20:269-74. 2007
  9. doi request reprint [Natural history of multiple sclerosis]
    Sandra Vukusic
    Service de Neurologie A, centre de coordination EDMUS pour la sclérose en plaques, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69677 Bron Cedex, France
    Presse Med 39:359-62. 2010
  10. doi request reprint Multiple sclerosis and epileptic seizures
    H Catenoix
    Service de Neurologie Fonctionnelle et d Epileptologie, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France
    Mult Scler 17:96-102. 2011

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Natural history of multiple sclerosis: a unifying concept
    Christian Confavreux
    Service de Neurologie A, the European Database for Multiple Sclerosis EDMUS Coordinating Center and INSERM U 433, Hopital Neurologique, Lyon, France
    Brain 129:606-16. 2006
    ....
  2. doi request reprint [Prevention of multiple sclerosis: a realistic goal?]
    S Vukusic
    Service de Neurologie A et Fondation Eugène Devic EDMUS pour la Sclérose en Plaques, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyon Bron Cedex, France
    Rev Neurol (Paris) 168:836-45. 2012
    ..In this context, greater knowledge of the aetiological factors, both genetic and environmental, may lead the way towards primary prevention strategies for MS in the near future...
  3. ncbi request reprint Pregnancy and multiple sclerosis: the children of PRIMS
    Sandra Vukusic
    The European Database for Multiple Sclerosis Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Clin Neurol Neurosurg 108:266-70. 2006
    ..The preventive effect of progesterone combined with estradiol on post partum relapses is about to be tested in a large randomized and placebo-controlled European trial, the POPART'MUS study...
  4. ncbi request reprint [Multiple sclerosis and pregnancy]
    S Vukusic
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59, boulevard Pinel, 69677 Bron Cedex
    Rev Neurol (Paris) 162:299-309. 2006
    ..The preventive effect of progesterone combined with estradiol on post partum relapses will be tested in a large-scale randomized and placebo-controlled European trial, the POPART'MUS study...
  5. ncbi request reprint Prognostic factors for progression of disability in the secondary progressive phase of multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyon Cedex 03, 69394, France
    J Neurol Sci 206:135-7. 2003
    ..We review here information available from the literature and from the Lyon MS database about this secondary progressive phase...
  6. ncbi request reprint Primary and secondary progressive multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyons Cedex 03, 69394, France
    J Neurol Sci 206:153-5. 2003
    ..A clue to this question could be the comparison between the different MS subtypes with a progressive phase. We discuss here the clinical similarities and differences between secondary and primary progressive MS...
  7. pmc Regional variations in the prevalence of multiple sclerosis in French farmers
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    J Neurol Neurosurg Psychiatry 78:707-9. 2007
    ..Studies on the prevalence of multiple sclerosis have been carried out worldwide, showing a heterogeneous distribution between countries and even between the different regions of the same country...
  8. ncbi request reprint Natural history of multiple sclerosis: risk factors and prognostic indicators
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    Curr Opin Neurol 20:269-74. 2007
    ..To highlight progress in the description of the natural course and prognosis of multiple sclerosis...
  9. doi request reprint [Natural history of multiple sclerosis]
    Sandra Vukusic
    Service de Neurologie A, centre de coordination EDMUS pour la sclérose en plaques, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69677 Bron Cedex, France
    Presse Med 39:359-62. 2010
    ..Recent studies suggest that the clinical phenotype of MS is mostly age-related and that relapses play a minimal role in the long-term accumulation of disability...
  10. doi request reprint Multiple sclerosis and epileptic seizures
    H Catenoix
    Service de Neurologie Fonctionnelle et d Epileptologie, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France
    Mult Scler 17:96-102. 2011
    ..The association between epilepsy and multiple sclerosis (MS) is not a coincidence...
  11. doi request reprint Persistent ocular motor manifestations and related visual consequences in multiple sclerosis
    C Tilikete
    INSERM U1028 and CNRS UMR 5292, Lyon Neuroscience Research Center, IMPACT team, Lyon, France
    Ann N Y Acad Sci 1233:327-34. 2011
    ..There was a correlation between the number of abnormal eye movements and visual functions. This study demonstrates that ocular motor dysfunction in MS induces specific visual dysfunction and handicap...
  12. ncbi request reprint The Prevention of Post-Partum Relapses with Progestin and Estradiol in Multiple Sclerosis (POPART'MUS) trial: rationale, objectives and state of advancement
    S Vukusic
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron F 69677, France
    J Neurol Sci 286:114-8. 2009
    ..The trial is registered under the reference NTC00127075...
  13. doi request reprint Reliability of longitudinal brain volume loss measurements between 2 sites in patients with multiple sclerosis: comparison of 7 quantification techniques
    F Durand-Dubief
    Service de Neurologie A et Fondation Eugène Devic EDMUS pour la Sclérose en Plaques, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron Cedex, France
    AJNR Am J Neuroradiol 33:1918-24. 2012
    ..Therefore, the purpose of this work was to assess the robustness of 7 different postprocessing algorithms applied to images acquired from different MR imaging systems...
  14. doi request reprint Mycophenolate mofetil may be effective in CNS sarcoidosis but not in sarcoid myopathy
    G Androdias
    Department of Neurology A, Hopital Neurologique, Hospices Civils de Lyon, France
    Neurology 76:1168-72. 2011
    ..To describe effectiveness, steroid-sparing effect, and tolerance of the antiproliferative immunosuppressant mycophenolate mofetil (MMF) in neurosarcoidosis...
  15. ncbi request reprint [Multiple sclerosis: spontaneous course, natural history]
    S Vukusic
    Service du Neurologie A, Pr Ch Confavreux, Hôpital Neurologique Pierre Wertheimer 59, boulevard Pinel, 69003 Lyon, France
    Rev Neurol (Paris) 157:753-6. 2001
    ..At the present time early prediction of outcome remains impossible. In the near future, new imaging techniques may provide a solution to this problem allowing selection of patients at risk who could benefit from early treatment...
  16. ncbi request reprint Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment
    X Perrot
    Department of Neurology A, Hopital Neurologique, Hospices Civils de Lyon, France
    Neurology 67:2256-8. 2006
    ..An important common feature was that, in seven cases, symptomatology occurred within 2 hours of first telithromycin intake--notably in cases of severe exacerbation...
  17. ncbi request reprint Natural history of multiple sclerosis: implications for counselling and therapy
    Christian Confavreux
    INSERM U 433, Service of Neurology A and EDMUS Coordinating Centre, Hopital Neurologique, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Curr Opin Neurol 15:257-66. 2002
    ..Thus multiple sclerosis should be considered to be as much neurodegenerative as inflammatory and disease-modifying therapeutic strategies should be reconsidered by focusing on protection and repair of the nervous system...
  18. ncbi request reprint Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process
    Christian Confavreux
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Lyon, France
    Brain 126:770-82. 2003
    ..Early assessable clinical variables significantly influence the time from the onset of multiple sclerosis to the assignment of a disability score of 4, but not the subsequent progression of irreversible disability...
  19. ncbi request reprint Non-specific immunosuppressants in the treatment of multiple sclerosis
    Christian Confavreux
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Clin Neurol Neurosurg 106:263-9. 2004
    ....
  20. ncbi request reprint The clinical epidemiology of multiple sclerosis
    Christian Confavreux
    Service de Neurologie A, Centre de Coordination EDMUS et INSERM U842, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Neuroimaging Clin N Am 18:589-622, ix-x. 2008
    ..Precise, consistent, and reliable data from appropriate cohorts have become available and knowledge is fairly comprehensive...
  21. ncbi request reprint [Multiple sclerosis: a degenerative disease?]
    Christian Confavreux
    Service de Neurologie A et Centre de Coordination EDMUS sur la sclérose en plaques, INSERM Unité 842, Hospices Civils de Lyon, Universite Lyon 1, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron
    Bull Acad Natl Med 192:483-91; discussion 492-3. 2008
    ..It will also be necessary to extinguish the slow-burning diffuse inflammation nested in the central nervous system behind the blood-brain barrier. This is the new therapeutic challenge in MS...
  22. doi request reprint The natural history of multiple sclerosis with childhood onset
    Christel Renoux
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France
    Clin Neurol Neurosurg 110:897-904. 2008
    ....
  23. ncbi request reprint NMO-IgG and Devic's neuromyelitis optica: a French experience
    Romain Marignier
    Service de Neurologie A and EDMUS Co ordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 59 boulevard Pinel Lyon Bron cedex, F 69677, France
    Mult Scler 14:440-5. 2008
    ..Our objectives were to replicate the test and to assess its usefulness...
  24. ncbi request reprint Accumulation of irreversible disability in multiple sclerosis: from epidemiology to treatment
    Christian Confavreux
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex 03, France
    Clin Neurol Neurosurg 108:327-32. 2006
    ....
  25. ncbi request reprint Age at disability milestones in multiple sclerosis
    Christian Confavreux
    The European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique, Hospices Civils de Lyon, Lyon, France
    Brain 129:595-605. 2006
    ..Aside acute focal recurrent inflammation and diffuse chronic neurodegeneration, accelerated ageing-related mechanisms may operate in the central nervous system of multiple sclerosis patients...
  26. ncbi request reprint [Cytoimmunological profile of cerebrospinal fluid in diagnosis of multiple sclerosis]
    Christiane Caudie
    Fédération de biologie, service d immunologie et de neuro immunologie, Hopital Neurologique et Neurochirurgical Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron, France
    Pathol Biol (Paris) 53:68-74. 2005
    ..65 x 10(-2)), IgG index for intrathecal synthesis of IgG is increased in 69% (N < 0.70), sensitive detection of oligoclonal IgG restricted to CSF by isoelectric focusing is positive in 91% (86-96%) with a specificity of 96% (93-99%)...
  27. ncbi request reprint [The natural history of multiple sclerosis]
    Christian Confavreux
    Service de Neurologie A, centre de coordination Edmus et Inserm U433, Hopital Neurologique Pierre Wertheimer, 69677 Lyon, Bron
    Rev Prat 56:1313-20. 2006
    ..In spite of the outstanding clinical polymorphism of MS, a unifying concept of the disease ("complexity vs heterogeneity") can be put forward...
  28. ncbi request reprint Pregnancy and multiple sclerosis (the PRIMS study): clinical predictors of post-partum relapse
    Sandra Vukusic
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Brain 127:1353-60. 2004
    ..This is, however, not sufficient to identify in advance women with multiple sclerosis who are more likely to relapse, especially for planning therapeutic trials aiming to prevent post-partum relapses...
  29. ncbi request reprint Natural history of multiple sclerosis with childhood onset
    Christel Renoux
    Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France
    N Engl J Med 356:2603-13. 2007
    ..The course and prognosis of childhood-onset multiple sclerosis have not been well described...
  30. ncbi request reprint [Sequential MRI imaging of progressive bilateral rostro-caudal medullary infarction]
    S Boulogne
    Service de Neurologie Vasculaire, Hopital Neurologique Pierre Wertheimer, 35, boulevard Pinel, 69500 Bron, France
    Rev Neurol (Paris) 170:277-9. 2014
    ..We report two patients who presented progressive quadriplegia, anarthia and dysphagia. Sequential MRI showed progressive constitution of the characteristic "heart appearance" sign. ..
  31. doi request reprint Primary angiitis of the central nervous system: response to mycophenolate mofetil
    F Chenevier
    Service de Neurologie A and the European Database for Multiple Sclerosis Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Lyon Bron Cedex, France
    J Neurol Neurosurg Psychiatry 80:1159-61. 2009
    ..Successful treatment with mycophenolate mofetil in combination with steroids is described...
  32. ncbi request reprint [Diagnostic criteria of different clinical forms ]
    C Confavreux
    Centre de Coordination Européen EDMUS European Database for MUltiple Sclerosis sur la Sclérose en Plaques, Service de Neurologie A, Hopital Neurologique, 59, bd Pinel, 69003 Lyon, France
    Rev Neurol (Paris) 157:907-13. 2001
    ..Time will say whether this new classification will replace the previous one...
  33. doi request reprint Acquired pendular nystagmus in multiple sclerosis and oculopalatal tremor
    C Tilikete
    INSERM U1028, Lyon Neuroscience Research Center, IMPACT team, Lyon, F 69000, France
    Neurology 76:1650-7. 2011
    ..The objective of our work was to compare in a prospective study clinical features, eye movement recording, and functional consequences of acquired pendular nystagmus in 14 patients with oculopalatal tremor and 20 patients with MS...
  34. doi request reprint Metabotropic glutamate receptor type 1 autoantibody-associated cerebellitis: a primary autoimmune disease?
    Romain Marignier
    Service de Neurologie A and European Database for Multiple Sclerosis Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69677 Lyon Bron Cedex, France
    Arch Neurol 67:627-30. 2010
    ....
  35. doi request reprint Uveitis associated with multiple sclerosis
    Julie Le Scanff
    Department of Internal Medicine, Hospices Civils de Lyon, Hotel Dieu, 1 Place de l Hopital, 69288 Lyon Cedex 02, France
    Mult Scler 14:415-7. 2008
    ..The topography and timing of uveitis were not associated with any significant difference in MS course and prognosis. There was no difference in the course and prognosis in patients with or without uveitis...
  36. ncbi request reprint Neuromyelitis optica IgG predicts relapse after longitudinally extensive transverse myelitis
    Brian G Weinshenker
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Ann Neurol 59:566-9. 2006
    ..We investigated whether neuromyelitis optica (NMO) IgG seropositivity at the initial presentation of longitudinally extensive transverse myelitis (LETM) predicts relapse of myelitis or development of optic neuritis...
  37. ncbi request reprint [Multiple sclerosis (MS), an inflammatory or degenerative disease?]
    Christian Confavreux
    Presse Med 33:151-2. 2004
  38. ncbi request reprint Steroid hormones in multiple sclerosis
    Martine El-Etr
    INSERM U 488, Le Kremlin Bicetre, France
    J Neurol Sci 233:49-54. 2005
    ..These clinical and experimental data have led to consider sexual steroids as potential therapeutic tools for preventing relapses in women with MS, in particular in the post-partum period...
  39. ncbi request reprint [Autoimmune hepatitis associated with multiple sclerosis]
    Céline Corrieri-Baizeau
    Gastroenterol Clin Biol 28:1186-7. 2004
  40. ncbi request reprint European validation of a standardized clinical description of multiple sclerosis
    Maria Pia Amato
    Department of Neurological Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy
    J Neurol 251:1472-80. 2004
    ....