Arnaud Hot

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. pmc Safety and efficacy of rituximab treatment for vasculitis in hepatitis B virus-associated type II cryoglobulinemia: a case report
    Florian Pasquet
    Department of Internal Medicine, Hopital Edouard Herriot, Lyon, France
    J Med Case Rep 6:39. 2012
  2. doi IL-17 and tumour necrosis factor α combination induces a HIF-1α-dependent invasive phenotype in synoviocytes
    Arnaud Hot
    Department of Clinical Immunology and Rheumatology and Immunogenomics and Inflammation Research Unit, Hopital Edouard Herriot, University of Lyon 1, Lyon, France
    Ann Rheum Dis 71:1393-401. 2012
  3. doi Reactive hemophagocytic syndrome in adult-onset Still disease: clinical features and long-term outcome: a case-control study of 8 patients
    Arnaud Hot
    Service de Medecine Interne, HCL Biomérieux, Hopital Edouard Herriot, Lyon, France
    Medicine (Baltimore) 89:37-46. 2010
  4. ncbi Successful treatment of cytomegalovirus-associated hemophagocytic syndrome by intravenous immunoglobulins
    Arnaud Hot
    Service de Medecine Interne, Hopital Edouard Herriot, Universite Claude Bernard, Lyon, France
    Am J Hematol 83:159-62. 2008
  5. doi Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells
    Arnaud Hot
    Department of Immunology and Rheumatology and the Immunogenomics and inflammation, Hospices Civils de Lyon, University of Lyon 1 mixed research unit, Hospital Edouard Herriot, Lyon, France
    Ann Rheum Dis 72:754-60. 2013
  6. doi Combination of IL-17 and TNFα induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells
    Arnaud Hot
    Department of Clinical Immunology and Rheumatology, Immunogenomics and Infl ammation Research Unit, Hopital Edouard Herriot, University of Lyon, Lyon, France
    Ann Rheum Dis 71:768-76. 2012
  7. pmc Importance of correlation between gene expression levels: application to the type I interferon signature in rheumatoid arthritis
    Frederic Reynier
    Joint Unit Hospices Civils de Lyon bioMérieux, Hopital Edouard Herriot, Lyon, France
    PLoS ONE 6:e24828. 2011
  8. doi Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition
    Myew Ling Toh
    Department of Immunology and Rheumatology, Immunogenomics and inflammation research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France
    Ann Rheum Dis 69:1562-7. 2010
  9. doi Yield of bone marrow examination in diagnosing the source of fever of unknown origin
    Arnaud Hot
    Service de Medecine Interne, Hopital Edouard Herriot, 5 Place d Arsonval, 69437 Lyon Cedex 03, France
    Arch Intern Med 169:2018-23. 2009
  10. doi Severe autoimmune cytopenias in treatment-naive hepatitis C virus infection: clinical description of 16 cases
    Jean Francois Dufour
    Department of Internal Medicine, University Claude Bernard, Lyon 1, Lyon, France
    Eur J Gastroenterol Hepatol 21:245-53. 2009

Collaborators

Detail Information

Publications11

  1. pmc Safety and efficacy of rituximab treatment for vasculitis in hepatitis B virus-associated type II cryoglobulinemia: a case report
    Florian Pasquet
    Department of Internal Medicine, Hopital Edouard Herriot, Lyon, France
    J Med Case Rep 6:39. 2012
    ..abstract:..
  2. doi IL-17 and tumour necrosis factor α combination induces a HIF-1α-dependent invasive phenotype in synoviocytes
    Arnaud Hot
    Department of Clinical Immunology and Rheumatology and Immunogenomics and Inflammation Research Unit, Hopital Edouard Herriot, University of Lyon 1, Lyon, France
    Ann Rheum Dis 71:1393-401. 2012
    ..To examine the effect of interleukin-17 (IL-17) on rheumatoid arthritis (RA) synoviocyte migration and invasiveness...
  3. doi Reactive hemophagocytic syndrome in adult-onset Still disease: clinical features and long-term outcome: a case-control study of 8 patients
    Arnaud Hot
    Service de Medecine Interne, HCL Biomérieux, Hopital Edouard Herriot, Lyon, France
    Medicine (Baltimore) 89:37-46. 2010
    ..Low haptoglobin levels, very high ferritin levels (>10,000 microg/L), and a normal or low neutrophil count seem to be predictive factors of the occurrence of RHS in AOSD...
  4. ncbi Successful treatment of cytomegalovirus-associated hemophagocytic syndrome by intravenous immunoglobulins
    Arnaud Hot
    Service de Medecine Interne, Hopital Edouard Herriot, Universite Claude Bernard, Lyon, France
    Am J Hematol 83:159-62. 2008
    ..IVIG was administered after the diagnosis of CMV-associated VAHS. Her symptoms and laboratory abnormalities improved dramatically after the onset of the treatment and she did not require antiviral agent...
  5. doi Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells
    Arnaud Hot
    Department of Immunology and Rheumatology and the Immunogenomics and inflammation, Hospices Civils de Lyon, University of Lyon 1 mixed research unit, Hospital Edouard Herriot, Lyon, France
    Ann Rheum Dis 72:754-60. 2013
    ..The aim of this study was to assess whether simvastatin modulates the vascular effects of interleukin (IL)-17, an emerging actor in atherosclerosis...
  6. doi Combination of IL-17 and TNFα induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells
    Arnaud Hot
    Department of Clinical Immunology and Rheumatology, Immunogenomics and Infl ammation Research Unit, Hopital Edouard Herriot, University of Lyon, Lyon, France
    Ann Rheum Dis 71:768-76. 2012
    ..To study the role of cytokines in these observations, the effects of tumour necrosis factor α (TNFα) and interleukin (IL)-17, a classical and a new key player in RA, were assessed in endothelial cell (EC) dysfunction...
  7. pmc Importance of correlation between gene expression levels: application to the type I interferon signature in rheumatoid arthritis
    Frederic Reynier
    Joint Unit Hospices Civils de Lyon bioMérieux, Hopital Edouard Herriot, Lyon, France
    PLoS ONE 6:e24828. 2011
    ..Here, we investigated the co-expression patterns in gene expression data and proposed a correlation-based research method to stratify individuals...
  8. doi Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition
    Myew Ling Toh
    Department of Immunology and Rheumatology, Immunogenomics and inflammation research Unit EA 4130, University of Lyon, Edouard Herriot Hospital, Lyon, France
    Ann Rheum Dis 69:1562-7. 2010
    ..Patients with rheumatoid arthritis (RA) have a systemic Th1 defect associated with inflammation...
  9. doi Yield of bone marrow examination in diagnosing the source of fever of unknown origin
    Arnaud Hot
    Service de Medecine Interne, Hopital Edouard Herriot, 5 Place d Arsonval, 69437 Lyon Cedex 03, France
    Arch Intern Med 169:2018-23. 2009
    ..The role of tissue biopsy is crucial in the diagnostic approach. We report a series of 130 consecutive patients with FUO who had undergone a bone marrow biopsy (BMB)...
  10. doi Severe autoimmune cytopenias in treatment-naive hepatitis C virus infection: clinical description of 16 cases
    Jean Francois Dufour
    Department of Internal Medicine, University Claude Bernard, Lyon 1, Lyon, France
    Eur J Gastroenterol Hepatol 21:245-53. 2009
    ..To describe the prevalence, main characteristics, and treatment of severe autoimmune cytopenias [autoimmune hemolytic anemia (AIHA), autoimmune thrombocytopenic purpura (AITP)] in patients with chronic hepatitis C virus (HCV) infection...
  11. ncbi Marked improvement of Churg-Strauss vasculitis with intravenous gamma globulins during pregnancy
    Arnaud Hot
    Service de Medecine Interne, Hopital Edouard Herriot, 3 Place Arsonval, Lyon, Cedex 03, 69003, France
    Clin Rheumatol 26:2149-51. 2007
    ..We discuss the indication of IVIg during the course of anti-neutrophil cytoplasm antigen (ANCA) vasculitis during the pregnancy...