Claude Guerin

..Further studies should investigate the effects of inhaled bronchodilators on patient outcome and methods to optimize delivery of inhaled bronchodilators during non-invasive ventilation...

..The goal of the present study was to compare 2 methods for correcting absolute P(es) values in terms of resulting P(pl,ee) and recommended PEEP...

..This experiment systematically compared both techniques in injured and non-injured lungs...

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..The objective of this study was to investigate the occurrence of EFL in two experimental models of ALI...

..To investigate the viscoelastic properties of lungs and thoracic wall in piglets...

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..To contrast the beneficial effects of the prone position on the lungs and the lack of proven clinical benefits on patient outcome...

..One drawback is hemodynamic impairment. To date, this strategy has not been found to be associated with an improvement of patient outcome...

..The conventional approach measures standardized base excess, bicarbonate (HCO₃⁻), and the anion gap...

..A recent trial showed that placing patients with acute lung injury in the prone position did not increase survival; however, whether those results hold true for patients with hypoxemic acute respiratory failure (ARF) is unclear...

..To deliver optimal PEEP to those ARDS patients with the highest lung recruitability, this technique should be monitored at the bedside. Alternative methods are under investigation as part of a decremental PEEP trial...

..In this review, we describe the balance between the beneficial effects and the harmful consequences of RM. Recent animal studies are discussed...

..We conducted a prospective physiologic short-term study in stable neuromuscular patients to determine the effects of IPBB, with and without abdominal belt, on regional lung ventilation...

..The device may benefit intubated and tracheotomized patients. We assessed the impact of various artificial airways on peak expiratory flow (PEF) with the CoughAssist...

..To describe the current practice of hemodialysis in acute renal failure (ARF) and to estimate the impact of hemodialysis modality on patient outcome...

..This study was conducted to decipher the respective effects of positive end-expiratory pressure and posture during lung injury on regional lung ventilation, perfusion and recruitment assessed by positron emission tomography...

..Little has been reported regarding either ICU management of acute respiratory failure (ARF) in the era of noninvasive mechanical ventilation (NIV) or long-term outcomes...

..To assess a sigmoidal equation for describing airway closure...

..We aimed at assessing the effect of APC on regional lung perfusion, aerated lung volume, cytokine production and oxygenation in experimental ALI...

..61) and PaCO(2) (R (2)=0.40) variations induced by PEEP. CONCLUSIONS: PET is a new reliable tool of scientific interest to image lung volume and alveolar recruitment during acute lung injury...

..Expiratory flow-volume (EFV) loops are continuously displayed on the screen of intensive care unit (ICU) ventilators...

..To determine whether gas exchange response to a first prone position session can predict patient outcome in hypoxemic acute respiratory failure...

..Both can also be used for intubated or tracheotomized patients. We assessed the impact of various artificial airways on the ability of the Alpha 200 and CoughAssist to generate insufflated volume...

..Recruitment maneuvers are closely linked to the selection of positive end-expiratory pressure (PEEP), which is also a subject of debate...

..The sigmoidal equation is able to determine precisely the point of the maximal compliance increase of lung and chest wall...

..The objective was to estimate early-onset VAP occurrence in ICUs within 48 hours after admission...

..The patient was put back onto volume-controlled mode, and 2 days later there were no air leaks. In pressure-support ventilation, V(T) must be closely monitored to ensure lung-protective mechanical ventilation...

..We describe our experience in early rehabilitation of ICU patients, and its effects on physiologic outcomes...

..CONCLUSIONS: Inflation and deflation V-P curves at different PEEPs can be fitted by the sigmoid equation. However, further work is needed to investigate the meaning of negative values for Pmci...

..To study the cardiorespiratory effects of inspiratory flow rate and waveform in COPD patients...

..To assess quality of life (QOL), mortality rate and renal function 6 months after onset of renal replacement therapy (RRT) for acute kidney injury (AKI) in the ICU...

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..96, P < 0.001) and injured (R(2) = 0.96, P < 0.001) animals. CONCLUSION: Measurement of (13)N-N(2) washout using PET is accurate to assess regional alveolar volume and ventilation during experimental acute lung injury...

..The strength of the association between intensive care unit (ICU)-acquired nosocomial infections (NIs) and mortality might differ according to the methodological approach taken...

..Better understanding of those changes may affect NIV management and improve our understanding of the relationship of night-to-night variability of respiratory and sleep variables and morning gas exchange...

..krusei. A reduction in the proportion of C. krusei isolates was observed from 2000-2010 (P = 0.028) as a result of its decreased recovery in the hematological department...

..2 +/- 8% to 30.4 +/- 7% (p < 0.05). CONCLUSIONS: Pigs in the PP had altered gravitational dependence of PBF compared to that observed when pigs were in the SP. This effect was enhanced by using a PEEP of 10 cm H(2)O...

..The C(max,rs) values found with the two methods were similar. CONCLUSIONS: An LCFI less than or equal to 10 l/min seems to be a quick, safe, and reliable method to determine LIP(rs) and C(max,rs) at the bedside...

..To compare risk factors of early- (E) and late-onset (L) ventilator-associated pneumonia (VAP)...