Claude Guerin

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. doi request reprint Inhaled bronchodilator administration during mechanical ventilation: how to optimize it, and for which clinical benefit?
    Claude Guerin
    Creatis INSERM, CNRS, Lyon, France
    J Aerosol Med Pulm Drug Deliv 21:85-96. 2008
  2. ncbi request reprint Prone ventilation in acute respiratory distress syndrome
    Claude Guerin
    Réanimation Médicale, Hopital de la Croix Rousse, Hospices Civils de Lyon, Universite de Lyon, Créatis INSERM 1044, Lyon, France
    Eur Respir Rev 23:249-57. 2014
  3. doi request reprint Prone positioning in severe acute respiratory distress syndrome
    Claude Guerin
    Réanimation Médicale, Hopital de la Croix Rousse, Hospices Civils de Lyon Université de Lyon and Creatis INSERM 1044, Lyon, France
    N Engl J Med 368:2159-68. 2013
  4. doi request reprint Comparison of 2 correction methods for absolute values of esophageal pressure in subjects with acute hypoxemic respiratory failure, mechanically ventilated in the ICU
    Claude Guerin
    University of Lyon, Lyon, France
    Respir Care 57:2045-51. 2012
  5. pmc Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: an experimental study
    J C Richard
    Service de Réanimation Médicale et d Assistance Respiratoire, Hôpital de la Croix Rousse 103 Grande Rue de la Croix Rousse, Lyon, 69004, France
    Crit Care 13:R82. 2009
  6. pmc Efficacy and safety of recruitment maneuvers in acute respiratory distress syndrome
    Claude Guerin
    Service de Reanimation Medicale, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon, 69004 France
    Ann Intensive Care 1:9. 2011
  7. doi request reprint Performance of the coughassist insufflation-exsufflation device in the presence of an endotracheal tube or tracheostomy tube: a bench study
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Respir Care 56:1108-14. 2011
  8. ncbi request reprint Measurement of respiratory system resistance during mechanical ventilation
    Claude Guerin
    Hôpital de la Croix Rousse and Université de Lyon, Service de Reanimation Medicale, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Intensive Care Med 33:1046-9. 2007
  9. ncbi request reprint Viscoelastic properties of lungs and thoracic wall of anesthetized mechanically ventilated piglets
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Vet Anaesth Analg 34:331-8. 2007
  10. ncbi request reprint Ventilation in the prone position in patients with acute lung injury/acute respiratory distress syndrome
    Claude Guerin
    Medical Intensive Care Unit and Ventilatory Assistance and CREATIS, Research and Applications Center in Image and Signal Processing, Lyon, France
    Curr Opin Crit Care 12:50-4. 2006

Collaborators

Detail Information

Publications49

  1. doi request reprint Inhaled bronchodilator administration during mechanical ventilation: how to optimize it, and for which clinical benefit?
    Claude Guerin
    Creatis INSERM, CNRS, Lyon, France
    J Aerosol Med Pulm Drug Deliv 21:85-96. 2008
    ..Further studies should investigate the effects of inhaled bronchodilators on patient outcome and methods to optimize delivery of inhaled bronchodilators during non-invasive ventilation...
  2. ncbi request reprint Prone ventilation in acute respiratory distress syndrome
    Claude Guerin
    Réanimation Médicale, Hopital de la Croix Rousse, Hospices Civils de Lyon, Universite de Lyon, Créatis INSERM 1044, Lyon, France
    Eur Respir Rev 23:249-57. 2014
    ..From the currently available data, prone positioning should be used as a first-line therapy in patients with severe ALI/ARDS. ..
  3. doi request reprint Prone positioning in severe acute respiratory distress syndrome
    Claude Guerin
    Réanimation Médicale, Hopital de la Croix Rousse, Hospices Civils de Lyon Université de Lyon and Creatis INSERM 1044, Lyon, France
    N Engl J Med 368:2159-68. 2013
    ..We evaluated the effect of early application of prone positioning on outcomes in patients with severe ARDS...
  4. doi request reprint Comparison of 2 correction methods for absolute values of esophageal pressure in subjects with acute hypoxemic respiratory failure, mechanically ventilated in the ICU
    Claude Guerin
    University of Lyon, Lyon, France
    Respir Care 57:2045-51. 2012
    ..The goal of the present study was to compare 2 methods for correcting absolute P(es) values in terms of resulting P(pl,ee) and recommended PEEP...
  5. pmc Electrical impedance tomography compared to positron emission tomography for the measurement of regional lung ventilation: an experimental study
    J C Richard
    Service de Réanimation Médicale et d Assistance Respiratoire, Hôpital de la Croix Rousse 103 Grande Rue de la Croix Rousse, Lyon, 69004, France
    Crit Care 13:R82. 2009
    ..This experiment systematically compared both techniques in injured and non-injured lungs...
  6. pmc Efficacy and safety of recruitment maneuvers in acute respiratory distress syndrome
    Claude Guerin
    Service de Reanimation Medicale, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon, 69004 France
    Ann Intensive Care 1:9. 2011
    ..In this review, we describe the balance between the beneficial effects and the harmful consequences of RM. Recent animal studies are discussed...
  7. doi request reprint Performance of the coughassist insufflation-exsufflation device in the presence of an endotracheal tube or tracheostomy tube: a bench study
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Respir Care 56:1108-14. 2011
    ..The device may benefit intubated and tracheotomized patients. We assessed the impact of various artificial airways on peak expiratory flow (PEF) with the CoughAssist...
  8. ncbi request reprint Measurement of respiratory system resistance during mechanical ventilation
    Claude Guerin
    Hôpital de la Croix Rousse and Université de Lyon, Service de Reanimation Medicale, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Intensive Care Med 33:1046-9. 2007
    ....
  9. ncbi request reprint Viscoelastic properties of lungs and thoracic wall of anesthetized mechanically ventilated piglets
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Vet Anaesth Analg 34:331-8. 2007
    ..To investigate the viscoelastic properties of lungs and thoracic wall in piglets...
  10. ncbi request reprint Ventilation in the prone position in patients with acute lung injury/acute respiratory distress syndrome
    Claude Guerin
    Medical Intensive Care Unit and Ventilatory Assistance and CREATIS, Research and Applications Center in Image and Signal Processing, Lyon, France
    Curr Opin Crit Care 12:50-4. 2006
    ..To contrast the beneficial effects of the prone position on the lungs and the lack of proven clinical benefits on patient outcome...
  11. ncbi request reprint Effects of inhaled fenoterol and positive end-expiratory pressure on the respiratory mechanics of patients with chronic obstructive pulmonary disease
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon
    Can Respir J 12:329-35. 2005
    ....
  12. ncbi request reprint Current ventilatory management of patients with acute lung injury/acute respiratory distress syndrome
    Claude Guerin
    Professor of Critical Care Medicine and Head, , , 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Expert Rev Respir Med 2:119-33. 2008
    ..One drawback is hemodynamic impairment. To date, this strategy has not been found to be associated with an improvement of patient outcome...
  13. ncbi request reprint The preventive role of higher PEEP in treating severely hypoxemic ARDS
    C Guerin
    Service de Reanimation Medicale, Hopital de la Croix Rousse, Lyon, France
    Minerva Anestesiol 77:835-45. 2011
    ..To deliver optimal PEEP to those ARDS patients with the highest lung recruitability, this technique should be monitored at the bedside. Alternative methods are under investigation as part of a decremental PEEP trial...
  14. ncbi request reprint Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial
    Claude Guerin
    Service de Reanimation Medicale, Hopital de la Croix Rousse, Lyon, France
    JAMA 292:2379-87. 2004
    ..A recent trial showed that placing patients with acute lung injury in the prone position did not increase survival; however, whether those results hold true for patients with hypoxemic acute respiratory failure (ARF) is unclear...
  15. doi request reprint A study of experimental acute lung injury in pigs on zero end-expiratory pressure
    Claude Guerin
    Service de Réanimation Médicale et Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Vet Anaesth Analg 35:122-31. 2008
    ..The objective of this study was to investigate the occurrence of EFL in two experimental models of ALI...
  16. ncbi request reprint Quantitative analysis of acid-base disorders in patients with chronic respiratory failure in stable or unstable respiratory condition
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Respir Care 55:1453-63. 2010
    ..The conventional approach measures standardized base excess, bicarbonate (HCO₃⁻), and the anion gap...
  17. ncbi request reprint Intermittent versus continuous renal replacement therapy for acute renal failure in intensive care units: results from a multicenter prospective epidemiological survey
    Claude Guerin
    Service de Réanimation Médicale et Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69317 Lyon, France
    Intensive Care Med 28:1411-8. 2002
    ..To describe the current practice of hemodialysis in acute renal failure (ARF) and to estimate the impact of hemodialysis modality on patient outcome...
  18. ncbi request reprint The short-term effects of intermittent positive pressure breathing treatments on ventilation in patients with neuromuscular disease
    Claude Guerin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Respir Care 55:866-72. 2010
    ..We conducted a prospective physiologic short-term study in stable neuromuscular patients to determine the effects of IPBB, with and without abdominal belt, on regional lung ventilation...
  19. doi request reprint Effects of prone position and positive end-expiratory pressure on lung perfusion and ventilation
    Jean Christophe Richard
    Hospices Civils de Lyon, Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Crit Care Med 36:2373-80. 2008
    ..This study was conducted to decipher the respective effects of positive end-expiratory pressure and posture during lung injury on regional lung ventilation, perfusion and recruitment assessed by positron emission tomography...
  20. ncbi request reprint Effect of activated protein C on pulmonary blood flow and cytokine production in experimental acute lung injury
    Jean Christophe Richard
    Service de Reanimation Medicale, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004, Lyon, France
    Intensive Care Med 33:2199-206. 2007
    ..We aimed at assessing the effect of APC on regional lung perfusion, aerated lung volume, cytokine production and oxygenation in experimental ALI...
  21. ncbi request reprint Alveolar recruitment assessed by positron emission tomography during experimental acute lung injury
    Jean Christophe Richard
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 93 Grande Rue de la Croix Rousse, 69004, Lyon, France
    Intensive Care Med 32:1889-94. 2006
    ..To compare changes in aerated lung volumes measured by positron emission tomography (PET) and inflation volume-pressure curve (V-P) of the respiratory system, and to evaluate the reliability of PET to assess alveolar recruitment...
  22. doi request reprint Management and long-term outcome of patients with chronic neuromuscular disease admitted to the intensive care unit for acute respiratory failure: a single-center retrospective study
    Ghislain Flandreau
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Respir Care 56:953-60. 2011
    ..Little has been reported regarding either ICU management of acute respiratory failure (ARF) in the era of noninvasive mechanical ventilation (NIV) or long-term outcomes...
  23. doi request reprint Evaluation of recruited lung volume at inspiratory plateau pressure with PEEP using bedside digital chest X-ray in patients with acute lung injury/ARDS
    Florent Wallet
    Medical ICU, Lyon, France
    Respir Care 58:416-23. 2013
    ....
  24. ncbi request reprint Sigmoidal equation for lung and chest wall volume-pressure curves in acute respiratory failure
    Cécile Pereira
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 69004 Lyon, France
    J Appl Physiol 95:2064-71. 2003
    ..The sigmoidal equation is able to determine precisely the point of the maximal compliance increase of lung and chest wall...
  25. ncbi request reprint Assessment of airway closure from deflation lung volume-pressure curve: sigmoidal equation revisited
    Frederique Bayle
    Hopital de la Croix Rousse, Service de Réanimation Médicale et d Assistance Respiratoire, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Intensive Care Med 32:894-8. 2006
    ..To assess a sigmoidal equation for describing airway closure...
  26. doi request reprint Expiratory flow-volume loop profile and patient outcome in chronic obstructive pulmonary disease in acute respiratory failure: a prospective observational study in a single intensive care unit
    Véronique Porot
    Service de Reanimation Medicale, hôpital de Croix Rousse, Lyon, France
    Respiration 84:27-35. 2012
    ..Expiratory flow-volume (EFV) loops are continuously displayed on the screen of intensive care unit (ICU) ventilators...
  27. ncbi request reprint Does gas exchange response to prone position predict mortality in hypoxemic acute respiratory failure?
    Stephane Lemasson
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 103, Grande rue de la Croix Rousse, Lyon, France
    Intensive Care Med 32:1987-93. 2006
    ..To determine whether gas exchange response to a first prone position session can predict patient outcome in hypoxemic acute respiratory failure...
  28. doi request reprint Comparison of Alpha 200 and CoughAssist as intermittent positive pressure breathing devices: a bench study
    Gael Bourdin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, France
    Respir Care 57:1129-36. 2012
    ..Both can also be used for intubated or tracheotomized patients. We assessed the impact of various artificial airways on the ability of the Alpha 200 and CoughAssist to generate insufflated volume...
  29. ncbi request reprint Comparison of optimal positive end-expiratory pressure and recruitment maneuvers during lung-protective mechanical ventilation in patients with acute lung injury/acute respiratory distress syndrome
    Michel Badet
    Service de Réanimation Médicale et Assistance Respiratoire, Hopital de la Croix Rousse, 69004 Lyon, France
    Respir Care 54:847-54. 2009
    ..Recruitment maneuvers are closely linked to the selection of positive end-expiratory pressure (PEEP), which is also a subject of debate...
  30. pmc Early-onset ventilator-associated pneumonia incidence in intensive care units: a surveillance-based study
    Philippe Vanhems
    Hospices Civils de Lyon, Infection Control Unit, Edouard Herriot Hospital, Lyon, France
    BMC Infect Dis 11:236. 2011
    ..The objective was to estimate early-onset VAP occurrence in ICUs within 48 hours after admission...
  31. ncbi request reprint The feasibility of early physical activity in intensive care unit patients: a prospective observational one-center study
    Gael Bourdin
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Respir Care 55:400-7. 2010
    ..We describe our experience in early rehabilitation of ICU patients, and its effects on physiologic outcomes...
  32. ncbi request reprint A case of pneumomediastinum in a patient with acute respiratory distress syndrome on pressure support ventilation
    Veronique Leray
    Service de Reanimation Medicale, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Respir Care 55:770-3. 2010
    ..The patient was put back onto volume-controlled mode, and 2 days later there were no air leaks. In pressure-support ventilation, V(T) must be closely monitored to ensure lung-protective mechanical ventilation...
  33. ncbi request reprint Effects of positive end-expiratory pressure and body position on pulmonary blood flow redistribution in mechanically ventilated normal pigs
    Jean Christophe Richard
    Centre Etude et de Recherches en Tomographie par Emission de Positrons, Hôpital Neuro Cardiologique, Lyon, France
    Chest 122:998-1005. 2002
    ..To assess the respective effects of position and positive end-expiratory pressure (PEEP) on the distribution of regional pulmonary blood flow (PBF)...
  34. ncbi request reprint Effects of positive end-expiratory pressure on the sigmoid equation in experimental acute lung injury
    Frederique Bayle
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Intensive Care Med 30:2121-5. 2004
    ..To describe inflation and deflation volume-pressure (V-P) curves of the respiratory system by the sigmoidal equation at different levels of positive end-expiratory pressure (PEEP) in acute lung injury...
  35. doi request reprint Bench assessment of a new insufflation-exsufflation device
    Véronique Porot
    Service de Reanimation Medicale, Hopital de la Croix Rousse, Hospices Civils de Lyon, Universite de Lyon, Lyon, France
    Respir Care 58:1536-40. 2013
    ..The Nippy Clearway is a new mechanical insufflation-exsufflation device used to assist cough...
  36. ncbi request reprint Sleep and respiratory function after withdrawal of noninvasive ventilation in patients with chronic respiratory failure
    Thierry Petitjean
    Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
    Respir Care 53:1316-23. 2008
    ..Better understanding of those changes may affect NIV management and improve our understanding of the relationship of night-to-night variability of respiratory and sleep variables and morning gas exchange...
  37. doi request reprint Six-month outcome in acute kidney injury requiring renal replacement therapy in the ICU: a multicentre prospective study
    B Delannoy
    Service de Réanimation Médicale et Assistance Respiratoire, Hopital de la Croix Rousse, CHU de Lyon and Université de Lyon, 103 Grande Rue de la Croix Rousse, 69004, Lyon, France
    Intensive Care Med 35:1907-15. 2009
    ..To assess quality of life (QOL), mortality rate and renal function 6 months after onset of renal replacement therapy (RRT) for acute kidney injury (AKI) in the ICU...
  38. ncbi request reprint Physiological effects of constant versus decelerating inflation flow in patients with chronic obstructive pulmonary disease under controlled mechanical ventilation
    Claude Guerin
    Service de Reanimation Medicale, Centre Hospitalier Lyon Sud, 69495 Pierre Benite Cedex, France
    Intensive Care Med 28:164-9. 2002
    ..To study the cardiorespiratory effects of inspiratory flow rate and waveform in COPD patients...
  39. ncbi request reprint Quantitative assessment of regional alveolar ventilation and gas volume using 13N-N2 washout and PET
    Jean Christophe Richard
    Service de Réanimation Médicale et d Assistance Respiratoire, Lyon, France
    J Nucl Med 46:1375-83. 2005
    ..This study aims to validate Va and a regional assessment with PET, using inhaled (13)N-N(2) in pigs...
  40. doi request reprint Estimating attributable mortality due to nosocomial infections acquired in intensive care units
    Jean Marie Januel
    Laboratory of Biometry and Evolutionary Biology, CNRS, UMR 5558, Claude Bernard University of Lyon, Lyon, France
    Infect Control Hosp Epidemiol 31:388-94. 2010
    ..The strength of the association between intensive care unit (ICU)-acquired nosocomial infections (NIs) and mortality might differ according to the methodological approach taken...
  41. ncbi request reprint Inspiratory pressure-volume curves obtained using automated low constant flow inflation and automated occlusion methods in ARDS patients with a new device
    Quentin Blanc
    Service de Réanimation Médicale et Assistance Respiratoire, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004 Lyon, France
    Intensive Care Med 28:990-4. 2002
    ....
  42. doi request reprint The impact of patient positioning on pressure ulcers in patients with severe ARDS: results from a multicentre randomised controlled trial on prone positioning
    Raphaele Girard
    Réanimation Médicale, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69004, Lyon, France
    Intensive Care Med 40:397-403. 2014
    ..However, a higher frequency of pressure ulcers has been reported in patients in the prone position. The objective of this study was to verify the impact of prone positioning on pressure ulcers in patients with severe ARDS...
  43. doi request reprint Absence of airway secretion accumulation predicts tolerance of noninvasive ventilation in subjects with amyotrophic lateral sclerosis
    Nadia Vandenberghe
    Service d Electroneuromyographie et Service de Neurologie C, Centre Sclérose Latérale Amyotrophique de Lyon, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    Respir Care 58:1424-32. 2013
    ..To assess factors that predict good tolerance of noninvasive ventilation (NIV), in order to improve survival and quality of life in subjects with amyotrophic lateral sclerosis...
  44. ncbi request reprint Idiopathic acute eosinophilic pneumonia: a study of 22 patients
    Francois Philit
    Service d Assistance Respiratoire et Réanimation Médicale, Hopital de la Croix Rousse, Paris, France
    Am J Respir Crit Care Med 166:1235-9. 2002
    ....
  45. doi request reprint Candida albicans and non-Candida albicans fungemia in an institutional hospital during a decade
    Laurence Parmeland
    Service de parasitologie et mycologie médicale, Hospices Civils de Lyon, 103, Grande rue de la Croix Rousse, 69004 Lyon, France
    Med Mycol 51:33-7. 2013
    ..krusei. A reduction in the proportion of C. krusei isolates was observed from 2000-2010 (P = 0.028) as a result of its decreased recovery in the hematological department...
  46. pmc Ward-specific rates of nasal cocolonization with methicillin-susceptible and -resistant Staphylococcus spp. and potential impact on molecular methicillin-resistant Staphylococcus aureus screening tests
    Sophie Trouillet-Assant
    Department of Clinical Microbiology, Northern Hospital Group, Hospices Civils de Lyon, Lyon, France
    J Clin Microbiol 51:2418-20. 2013
    ..Such cocolonization can greatly influence the performance of molecular methicillin-resistant S. aureus (MRSA) screening tests depending on the methods used and targets selected...
  47. ncbi request reprint Questions on the reversibility of lung collapse in early acute ARDS
    Claude Guerin
    Am J Respir Crit Care Med 177:555; author reply 555. 2008
  48. ncbi request reprint Prone positioning: do not turn it off!
    Claude Guerin
    Intensive Care Med 31:1012-3. 2005
  49. doi request reprint Early- and late-onset ventilator-associated pneumonia acquired in the intensive care unit: comparison of risk factors
    Marine Giard
    Laboratory of Epidemiology and Public Health, CNRS UMR 5558, Lyon 1 University, 69008 Lyon, France
    J Crit Care 23:27-33. 2008
    ..To compare risk factors of early- (E) and late-onset (L) ventilator-associated pneumonia (VAP)...