V Cottin

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. ncbi request reprint [Churg-Strauss syndrome]
    V Cottin
    Service de Pneumologie, Hopital Louis Pradel, Universite Claude Bernard, BP Lyon Montchat, 69394 Lyon Cedex 03
    Rev Pneumol Clin 59:17-24. 2003
  2. ncbi request reprint [Idiopathic pulmonary fibrosis]
    Vincent Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, UMR 754, Université Lyon I, Bron
    Rev Prat 56:1165-71. 2006
  3. ncbi request reprint Pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: a series of 126 patients
    Vincent Cottin
    Centre de Référence pour les Maladies Orphelines Pulmonaires, Hopital Louis Pradel, Université Lyon I, UMR 754 INRA ENVL UCBL IFR 128, Lyon, France
    Medicine (Baltimore) 86:1-17. 2007
  4. ncbi request reprint Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease)
    Vincent Cottin
    Reference Center for Orphan Lung Disorders, Louis Pradel Hospital, Hospices Civils de Lyon, University Lyon I, Research Network on Rendu Osler Disease, Lyon, France
    Respiration 74:361-78. 2007
  5. ncbi request reprint Cryptogenic organizing pneumonia
    Vincent Cottin
    Hospices Civils de Lyon, Louis Pradel Hospital, National Reference Centre for Rare Pulmonary Diseases, Department of Respiratory Medicine, University Claude Bernard Lyon I, University of Lyon, Lyon, France
    Semin Respir Crit Care Med 33:462-75. 2012
  6. ncbi request reprint Diagnosis and management of idiopathic pulmonary fibrosis: French practical guidelines
    Vincent Cottin
    For a full list of the authors affiliations see the Acknowledgements section
    Eur Respir Rev 23:193-214. 2014
  7. ncbi request reprint Current approaches to the diagnosis and treatment of idiopathic pulmonary fibrosis in Europe: the AIR survey
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Lyon, France Université de Lyon, Universite Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, FranceHospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Lyon, France Université de Lyon, Universite Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, France
    Eur Respir Rev 23:225-30. 2014
  8. doi request reprint Management of idiopathic pulmonary fibrosis in France: a survey of 1244 pulmonologists
    V Cottin
    National Reference Centre for Rare Pulmonary Diseases, Louis Pradel University Hospital, Lyon, France Electronic address
    Respir Med 108:195-202. 2014
  9. doi request reprint Significance of connective tissue diseases features in pulmonary fibrosis
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Lyon, France
    Eur Respir Rev 22:273-80. 2013
  10. doi request reprint The impact of emphysema in pulmonary fibrosis
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, et centre de compétences de l hypertension artérielle pulmonaire, Lyon, France
    Eur Respir Rev 22:153-7. 2013

Detail Information

Publications94

  1. ncbi request reprint [Churg-Strauss syndrome]
    V Cottin
    Service de Pneumologie, Hopital Louis Pradel, Universite Claude Bernard, BP Lyon Montchat, 69394 Lyon Cedex 03
    Rev Pneumol Clin 59:17-24. 2003
    ..Treatment includes corticosteroids, which should be associated with immunosuppressive agents (cyclophosphamide) in severe cases...
  2. ncbi request reprint [Idiopathic pulmonary fibrosis]
    Vincent Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, UMR 754, Université Lyon I, Bron
    Rev Prat 56:1165-71. 2006
    ..Clinical trials are strongly needed in this still uncurable disease with median survival at 3 years of only about 50%...
  3. ncbi request reprint Pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia: a series of 126 patients
    Vincent Cottin
    Centre de Référence pour les Maladies Orphelines Pulmonaires, Hopital Louis Pradel, Université Lyon I, UMR 754 INRA ENVL UCBL IFR 128, Lyon, France
    Medicine (Baltimore) 86:1-17. 2007
    ....
  4. ncbi request reprint Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease)
    Vincent Cottin
    Reference Center for Orphan Lung Disorders, Louis Pradel Hospital, Hospices Civils de Lyon, University Lyon I, Research Network on Rendu Osler Disease, Lyon, France
    Respiration 74:361-78. 2007
    ..Pulmonary hypertension is detected by systematic examination of right cardiac cavities and tricuspid regurgitation flow at echocardiography, and the diagnosis is established by right heart catheterization...
  5. ncbi request reprint Cryptogenic organizing pneumonia
    Vincent Cottin
    Hospices Civils de Lyon, Louis Pradel Hospital, National Reference Centre for Rare Pulmonary Diseases, Department of Respiratory Medicine, University Claude Bernard Lyon I, University of Lyon, Lyon, France
    Semin Respir Crit Care Med 33:462-75. 2012
    ..Patients and clinicians must be aware of frequent relapses after stopping corticosteroid treatment...
  6. ncbi request reprint Diagnosis and management of idiopathic pulmonary fibrosis: French practical guidelines
    Vincent Cottin
    For a full list of the authors affiliations see the Acknowledgements section
    Eur Respir Rev 23:193-214. 2014
    ..All recommendations included in this article received at least 90% agreement by the reviewing panel. Herein, we summarise the main conclusions and practical recommendations of the French guidelines...
  7. ncbi request reprint Current approaches to the diagnosis and treatment of idiopathic pulmonary fibrosis in Europe: the AIR survey
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Lyon, France Université de Lyon, Universite Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, FranceHospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Lyon, France Université de Lyon, Universite Claude Bernard Lyon 1, INRA, UMR754 IFR 128, Lyon, France
    Eur Respir Rev 23:225-30. 2014
    ..This survey, when taken together with the French survey, suggests that there is still a need to improve earlier diagnosis of IPF...
  8. doi request reprint Management of idiopathic pulmonary fibrosis in France: a survey of 1244 pulmonologists
    V Cottin
    National Reference Centre for Rare Pulmonary Diseases, Louis Pradel University Hospital, Lyon, France Electronic address
    Respir Med 108:195-202. 2014
    ..The present survey coordinated by the French expert centres for rare pulmonary diseases investigated French pulmonologists' current diagnostic and therapeutic practice for idiopathic pulmonary fibrosis (IPF)...
  9. doi request reprint Significance of connective tissue diseases features in pulmonary fibrosis
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Lyon, France
    Eur Respir Rev 22:273-80. 2013
    ..However, autoantibodies alone when present in IPF patients do not seem to impact prognosis or management. Referral to a rheumatologist and multidisciplinary discussion may contribute to management of patients with undifferentiated CTD. ..
  10. doi request reprint The impact of emphysema in pulmonary fibrosis
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, et centre de compétences de l hypertension artérielle pulmonaire, Lyon, France
    Eur Respir Rev 22:153-7. 2013
    ..Further studies are needed to ascertain the aetiology, morbidity, mortality and management of the CPFE syndrome, with or without PH, and to evaluate novel therapeutic options in CPFE...
  11. pmc The role of pirfenidone in the treatment of idiopathic pulmonary fibrosis
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Universite Claude Bernard Lyon 1, Lyon, France
    Respir Res 14:S5. 2013
    ..The efficacy data, coupled with long-term safety data, provide further evidence of a clinically-meaningful treatment effect with pirfenidone in patients with IPF...
  12. pmc Clinical case: Combined pulmonary fibrosis and emphysema with pulmonary hypertension--clinical management
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Universite Claude Bernard Lyon, Lyon, France
    BMC Res Notes 6:S2. 2013
    ..While CPFE is a strong determinant of secondary precapillary pulmonary hypertension (PH), there is limited evidence regarding the management of patients with CPFE and PH...
  13. doi request reprint Interstitial lung disease
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Universite de Lyon, Universite Claude Bernard Lyon 1, Lyon, France
    Eur Respir Rev 22:26-32. 2013
    ....
  14. doi request reprint Eosinophilic lung diseases
    Vincent Cottin
    Service de Pneumologie, Hospices Civils de Lyon, Centre de Référence National des Maladies Pulmonaires Rares, Hopital Louis Pradel, Lyon Cedex 69677, France
    Immunol Allergy Clin North Am 32:557-86. 2012
    ..All possible causes of eosinophilia (especially fungus infection or drug or toxic exposure) must be thoroughly investigated before the diagnosis of idiopathic disease is made...
  15. doi request reprint Combined pulmonary fibrosis and emphysema in connective tissue disease
    Vincent Cottin
    Hospices Civils de Lyon, National Reference Center for Rare Pulmonary Diseases, Department of Respiratory Medicine, Louis Pradel Hospital, University Claude Bernard Lyon 1, University of Lyon, UMR 754 INRA, Lyon, France
    Curr Opin Pulm Med 18:418-27. 2012
    ..This review discusses combined pulmonary fibrosis and emphysema (CPFE) in the setting of connective tissue disease...
  16. doi request reprint Changing the idiopathic pulmonary fibrosis treatment approach and improving patient outcomes
    Vincent Cottin
    Hopital Louis Pradel, Service de Pneumologie, Lyon, France
    Eur Respir Rev 21:161-7. 2012
    ..The pooled study results, coupled with recent data regarding the prognostic significance of changes in FVC and 6MWT, provide further evidence of a clinically meaningful treatment benefit with pirfenidone in patients with IPF...
  17. pmc Clinical highlights from the 2011 ERS Congress in Amsterdam
    Martijn A Spruit
    Program Development Centre of CIRO, centre of expertise for chronic organ failure, Horn, France
    Eur Respir J 39:1501-10. 2012
    ..The hot topics and selected abstracts from the scientific groups of the Clinical Assembly are discussed here in the context of recent literature...
  18. pmc Right-to-left shunt with hypoxemia in pulmonary hypertension
    Jean Frédéric Vodoz
    Service de pneumologie et centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, Lyon, France
    BMC Cardiovasc Disord 9:15. 2009
    ..Hypoxemia is common in pulmonary hypertension (PH) and may be partly related to ventilation/perfusion mismatch, low diffusion capacity, low cardiac output, and/or right-to-left (RL) shunting...
  19. doi request reprint [Pulmonary sarcoidosis: Diagnostic challenges]
    V Cottin
    Service de Pneumologie, centre de référence des maladies pulmonaires rares, Hopital Louis Pradel, Hospices Civils de Lyon, 28, avenue du doyen Lepine, 69677 Lyon Cedex, France
    Rev Med Interne 32:93-100. 2011
    ..In-depth knowledge of pulmonary sarcoidosis is required to ensure the diagnosis of this non-rare disorder of multiple presentation, to identify potentially severe cases and to guide therapeutic decision...
  20. ncbi request reprint [Idiopathic interstitial pneumonia: treatment]
    V Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Université Lyon I, 28, avenue du Doyen Lepine 69677 Lyon, France
    Rev Mal Respir 23:10S97-10S102. 2006
  21. ncbi request reprint Clinical genetics for the pulmonologist: introduction
    Vincent Cottin
    Department of Respiratory Diseases, Reference Center for Orphan Lung Disorders, Hospices Civils de Lyon, Louis Pradel Hospital, University Lyon I, UMR 754 INRA ENVL UCBL IFR 128, Lyon, France
    Respiration 74:3-7. 2007
  22. ncbi request reprint [Lipid pneumonia]
    Vincent Cottin
    centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Universite de Lyon, 69677 Lyon, Bron
    Rev Prat 57:21. 2007
  23. ncbi request reprint [Combined pulmonary fibrosis and emphysema]
    Vincent Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Lyon, France
    Presse Med 36:936-44. 2007
    ..Pulmonary hypertension is present in almost half of all patients and represents the principal negative prognostic factor for this condition, which has a median survival of 6 years...
  24. ncbi request reprint [Pulmonary rheumatoid nodule]
    Vincent Cottin
    centre de référence des maladies orphelines pulmonaires, Hospices Civils de Lyon, Universite de Lyon
    Presse Med 36:1214-5. 2007
  25. ncbi request reprint [Pulmonary MALT lymphoma]
    Vincent Cottin
    centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Universite de Lyon, 69677 Lyon, Bron
    Rev Prat 57:1636. 2007
  26. ncbi request reprint [Evidence based respiratory medicine. 6th update workshop of SPLF March 30th, 2007. Interstitial lung diseases]
    V Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de pneumologie et centre de référence des maladies orphelines pulmonaires, Universite Lyon 1, UMR 754 INRA UCBL ENVL, Lyon, France
    Rev Mal Respir 24:1162-7. 2007
  27. doi request reprint Syndrome of pleural and retrosternal "bridging" fibrosis and retroperitoneal fibrosis in patients with asbestos exposure
    V Cottin
    Hospices Civils de Lyon, Lyon I University, Louis Pradel Hospital, Department of Respiratory Diseases Reference Center for Orphan Lung Disorders, Lyon, France
    Thorax 63:177-9. 2008
    ..These cases represent an unusual new presentation of pleural and retrosternal fibrosis extending beyond the anatomical structures and associated with retroperitoneal fibrosis...
  28. ncbi request reprint [Interstitial lung disease in connective tissue diseases]
    Vincent Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, Université Lyon I, Universite de Lyon, UMR 754 INRA ENVL UCBL IFR128, 69677 Lyon, Bron
    Rev Prat 57:2235-42. 2007
    ..Little information is available regarding treatment of ILD in connective tissue disease. Clinically modest short-term efficacy of cyclophosphamide treatment has been shown in systemic sclerosis, but was not maintained at 2 years...
  29. doi request reprint [Idiopathic pulmonary fibrosis]
    Vincent Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, Université Lyon I, UMR 754 INRA ENVL IFR128, Lyon, France
    Presse Med 37:1581-90. 2008
    ..Clinical trials are in progress to improve the treatment of this still incurable disease...
  30. pmc Centrilobular emphysema combined with pulmonary fibrosis results in improved survival: a response
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de Pneumologie Centre de Référence National des Maladies Pulmonaires Rares, Lyon, France
    Fibrogenesis Tissue Repair 4:16. 2011
    ..Fibrogenesis & Tissue Repair 2011, 4:6.Please see related letter http://fibrogenesis.com/content/4/1/17...
  31. doi request reprint [Lymphangioleiomyomatosis]
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de pneumologie et centre de référence des maladies pulmonaires rares F 69677 Lyon Cedex, France
    Presse Med 39:116-25. 2010
    ..Hopes are high for mTor inhibitors (sirolimus and everolimus) and treatment trials are currently underway. Lung transplantation must be considered when chronic respiratory failure occurs in patients younger than 60 years...
  32. doi request reprint [Pulmonary hypertension in interstitial lung diseases: diagnostic and therapeutic approach in 2011?]
    Vincent Cottin
    Centre de Référence National des Maladies Pulmonaires Rares, Centre de Compétences de l HTAP, Service de Pneumologie, Hopital Louis Pradel, Hospices Civils de Lyon, Lyon, France
    Presse Med 40:1S39-45. 2011
    ..Pulmonary transplantation should be considered in the absence of contra-indication...
  33. ncbi request reprint [Clinical pathologic classification of idiopathic interstitial pneumonia: review and perspectives]
    Vincent Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de pneumologie et Centre de référence des maladies pulmonaires rares, Universite de Lyon, Universite Lyon 1, UMR 754, 28 avenue Doyen Lépine 69677 Bron
    Bull Acad Natl Med 194:327-40; discussion 340-2. 2010
    ..The classification is currently being revised in order to better integrate the recently identified syndrome of combined pulmonary fibrosis and emphysema, acute exacerbations of fibrosis, and new pathophysiologic and genetic findings...
  34. ncbi request reprint [Pulmonary arterial hypertension in connective tissue disease]
    V Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Hospices Civils de Lyon, Universite de Lyon, UMR 754 INRA ENVL UCBL IFR128, Lyon, France
    Rev Mal Respir 23:13S61-72. 2006
    ..PAH is defined by mean arterial pulmonary pressure > 25 mmHg at rest (or 30 mmHg during exercise) during right heart catheterisation...
  35. ncbi request reprint [Alveolar hemorrhages: observation]
    V Cottin
    Service de pneumologie Centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Université Lyon I, 28 avenue du Doyen Lepine, 69677 Lyon, France
    Rev Mal Respir 23:5S28-5S38. 2006
  36. ncbi request reprint Interstitial pulmonary amyloidosis
    Vincent Cottin
    Department of Pulmonary Medicine, Center for Orphan Lung Diseases, Louis Pradel University Hospital, Claude Bernard University, Lyon, France
    Respiration 75:210. 2008
  37. ncbi request reprint Pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia
    Vincent Cottin
    Service de Pneumologie, Centre des Maladies Orphelines Pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, 69677 Bron Cedex, France
    Am J Respir Crit Care Med 169:994-1000. 2004
    ..An alternative is to screen directly by chest CT. However, this algorithm may obviate the need for chest CT in patients without PAVM, who represent a majority of patients with hereditary hemorrhagic telangiectasia...
  38. ncbi request reprint [Wegener's granulomatosis]
    Vincent Cottin
    centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Lyon
    Rev Prat 56:129. 2006
  39. ncbi request reprint [Treatment of pulmonary fibrosis]
    Vincent Cottin
    Service de Pneumologie, Hopital Louis Pradel, 69394 Lyon
    Presse Med 31:1613-23. 2002
    ..Young patients should be assessed with a view of pulmonary transplantation...
  40. ncbi request reprint [Pulmonary manifestations of hereditary hemorrhagic telangiectasia]
    V Cottin
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Université Lyon I, Réseau de recherche sur la maladie de Rendu Osler, UMR 754, IFR 128 Lyon, France
    Rev Mal Respir 23:4S53-4S66. 2006
    ..It is estimated to affect at least one in ten thousand of the population in France. The diagnosis is clinical and depends on the association of epistaxis, telangiectasia, visceral manifestations of the disease, and familial occurrence...
  41. ncbi request reprint Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity
    V Cottin
    Groupe d Etudes et de Recherche sur les Maladies Orphelines Pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, Lyon Bron, France
    Eur Respir J 26:586-93. 2005
    ....
  42. doi request reprint [Alveolar hemorrhage]
    J Traclet
    INRA, UMR754 INRA Vetagrosup EPHE IFR 128, Universite de Lyon, Universite Claude Bernard Lyon 1, Lyon, France
    Rev Med Interne 34:214-23. 2013
    ..Treatment of non-immune DAH is that of its cause. Whatever the cause, DAH is an emergency requiring prompt assessment and early treatment...
  43. doi request reprint Characterisation of severe obliterative bronchiolitis in rheumatoid arthritis
    G Devouassoux
    Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service de Pneumologie, Pierre Benite, Universite de Lyon, France
    Eur Respir J 33:1053-61. 2009
    ..Obliterative bronchiolitis associated with rheumatoid arthritis is a severe and under-recognised condition leading to respiratory failure and death in a high proportion of patients...
  44. doi request reprint Persistent airflow obstruction in asthma of patients with Churg-Strauss syndrome and long-term follow-up
    V Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, centre de référence des maladies orphelines pulmonaires, Universite de Lyon, UCBL INRA ENVL EPHE, UMR, IFR, France
    Allergy 64:589-95. 2009
    ..Little is known about the long-term outcome of airflow obstruction in asthma of patients with Churg-Strauss syndrome (CSS)...
  45. ncbi request reprint [Pulmonary vascular manifestations in hereditary hemorrhagic telangiectasia]
    A S Blanchet
    Service de Pneumologie, Centre des Maladies Orphelines Pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Lyon
    Presse Med 34:1487-95. 2005
    ..Pulmonary arterial hypertension is rare in this disease. It may be due to systemic arteriovenous shunting in the liver, which increases cardiac output, or be similar to idiopathic pulmonary hypertension...
  46. ncbi request reprint [Nonspecific interstitial pneumonitis: a new anatomoclinical entity among idiopathic diffuse interstitial pneumonias]
    V Cottin
    Service de Pneumologie, , , Lyon, France
    Rev Mal Respir 18:25-33. 2001
    ..These etiologic and prognostic features justify the individualization of nonspecific interstitial pneumonitis with fibrosis as a distinct clinicopathological entity...
  47. ncbi request reprint [Urinary incontinence due to chronic cough in interstitial lung disease]
    F Bradaia
    Service de Pneumologie, centre de référence des maladies pulmonaires rares, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Lyon, France
    Rev Mal Respir 26:499-504. 2009
    ..In interstitial lung disease, chronic cough may lead to development of urinary incontinence, but the prevalence and impact of this symptom are unknown...
  48. ncbi request reprint Interstitial lung disease in amyopathic dermatomyositis, dermatomyositis and polymyositis
    V Cottin
    Dept of Respiratory Medicine, Louis Pradel Hospital, Claude Bernard University, Lyon, France
    Eur Respir J 22:245-50. 2003
    ..Survival at 5 yrs was 50%. This study shows the clinician should remain alert to potential muscular or cutaneous manifestations whenever a pathological diagnosis of nonspecific interstitial pneumonia is made...
  49. doi request reprint Respiratory failure with diffuse bronchiectases and cryoglobulinaemia
    N Girard
    Reference Center for Rare Lung Diseases, Dept of Respiratory Medicine, Louis Pradel Hospital, Hospices Civils de Lyon, Lyon I University, Lyon, France
    Eur Respir J 31:1374-8. 2008
  50. doi request reprint Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome
    V Cottin
    Hospices Civils de Lyon, Hopital Louis Pradel, Service de pneumologie Centre de référence des maladies pulmonaires rares, Universite de Lyon, Université Lyon I, UCBL INRA ENVL EPHE, UMR754, IFR128, Lyon, France
    Eur Respir J 35:105-11. 2010
    ....
  51. ncbi request reprint [Diffuse idiopathic interstitial pneumonias. International multidisciplinary consensus classification by the American Thoracic Society and the European Respiratory Society, principal clinico-pathological entities, and diagnosis]
    V Cottin
    Service de Pneumologie, Hopital Louis Pradel, Universite Claude Bernard, Lyon, France
    Rev Mal Respir 21:299-318. 2004
    ..The diagnosis is based on a multidisciplinary approach, integrating the clinical evaluation, the high-resolution computerised tomography, and the pathological pattern...
  52. doi request reprint [Interstitial lung disease and anti-TNF-alpha therapy in rheumatoid arthritis: Two different patterns?]
    A Schuller
    Service de Pneumologie, centre de référence des maladies pulmonaires rares, Hopital Louis Pradel, 69677 Lyon Cedex, France
    Rev Mal Respir 27:232-7. 2010
    ..Other features that may differ between these two presentations include the risk factors, the anti-TNF-alpha molecule used, the histopathological pattern, and the prognosis...
  53. ncbi request reprint Alveolar hemorrhage in anti-basement membrane antibody disease: a series of 28 cases
    Romain Lazor
    Department of Respiratory Medicine and Reference Center for Orphan Pulmonary Diseases, Louis Pradel Hospital, Claude Bernard University, Lyon, France
    Medicine (Baltimore) 86:181-93. 2007
    ..Renal outcome was excellent in the subgroup of patients with predominant pulmonary involvement...
  54. doi request reprint Isolated recurrent pleuritis revealing familial mediterranean Fever in adulthood
    J C Lega
    Reference Center for Rare Pulmonary Diseases, Department of Respiratory Medicine, Louis Pradel Hospital, Claude Bernard University Lyon I, Lyon, France
    Respiration 79:508-10. 2010
    ..Disappearance of attacks with one dose of colchicine (1 mg/day) strengthened the presumptive diagnosis of atypical FMF, which was further confirmed by genetic testing identifying the homozygous mutation M694I/M694I of the MEFV gene...
  55. ncbi request reprint Telomerase activation in a model of lung adenocarcinoma
    F Suau
    UMR754, Lyon Gerland, Université Lyon I, 50 avenue Tony Garnier, 69007 Lyon, France
    Eur Respir J 27:1175-82. 2006
    ..Further work is necessary to identify alternative signalling pathways of telomerase activation in tumours...
  56. ncbi request reprint Eosinophilic pneumonias
    V Cottin
    Department of Pulmonary Medicine, and Center for Orphan Lung Diseases, Louis Pradel University Hospital, Claude Bernard University, UMR 754 INRA ENVL UCBL and IFR128 Biosciences, Lyon, France
    Allergy 60:841-57. 2005
    ..The adjunction of immunosuppressants to corticosteroids is necessary in patients with CSS and poor prognosis factors. Imatinib has recently proven effective in the treatment of the myeloproliferative variant of the HES...
  57. doi request reprint Infiltrative lung diseases in pregnancy
    N Freymond
    Department of Respiratory Medicine, Reference Centre for Rare Pulmonary Diseases, Hospices Civils de Lyon, Louis Pradel Hospital, University of Lyon I, UMR754 INRA, IFR 128, Lyon, France
    Clin Chest Med 32:133-46, ix. 2011
    ..Preexisting ILD no longer contraindicates pregnancy systematically, but thorough evaluation of ILD before pregnancy is required to identify potential contraindications and adapt monitoring...
  58. doi request reprint Selected clinical highlights from the 2010 ERS Congress in Barcelona
    C Robalo Cordeiro
    Dept of Pulmonology, Coimbra University Hospital, Research Centre of Pulmonology, Coimbra University, Coimbra, Portugal
    Eur Respir J 38:209-17. 2011
    ....
  59. ncbi request reprint Chronic eosinophilic pneumonia after radiation therapy for breast cancer
    V Cottin
    Service de Pneumologie, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, Lyon, France
    Eur Respir J 23:9-13. 2004
    ....
  60. doi request reprint [Epstein-Barr virus associated pulmonary lymphoma in Sjögren's syndrome]
    J Traclet
    UMR 754, Service de Pneumologie, centre de référence des maladies pulmonaires rares, Hopital Louis Pradel, Universite de Lyon, 69677 Lyon Bron Cedex, France
    Rev Mal Respir 27:500-4. 2010
    ..The condition initially improved with rituximab-CHOP treatment, but recurrence of the lymphoma was fatal...
  61. ncbi request reprint FDG-PET improves tumour detection in patients with paraneoplastic neurological syndromes
    S Younes-Mhenni
    Neurology B, Hôpital Pierre Wertheimer, Universite Claude Bernard, Lyon, France
    Brain 127:2331-8. 2004
    ....
  62. doi request reprint [Unusual pulmonary presentation of systemic Langerhans cell histiocytosis]
    J C Lega
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital L Pradel, Universite Lyon 1, 28, avenue Lépine, 69677 Lyon, France
    Rev Med Interne 29:669-72. 2008
    ..Investigations revealed anterior and posterior hypopituitarism. An important improvement occurred with corticosteroid and vinblastine treatment...
  63. ncbi request reprint Hemorrhagic hereditary telangiectasia (Rendu-Osler disease) and infectious diseases: an underestimated association
    Sophie Dupuis-Girod
    Service de Génétique et Centre de Référence sur la Maladie de Rendu Osler, hôpital de l Hôtel dieu, Lyon, France
    Clin Infect Dis 44:841-5. 2007
    ..Cerebral infections accounted for 33% of all infections, were mainly due to multiple and anaerobic bacteria, and were associated with the presence of pulmonary arteriovenous malformations and a short duration of epistaxis...
  64. ncbi request reprint Genotype-phenotype correlations in hereditary hemorrhagic telangiectasia: data from the French-Italian HHT network
    Gaetan Lesca
    Service de Génétique Moléculaire et Médicale, Hopital Edouard Herriot, Lyon, France, and Genetica Medica, Università di Pavia and IRCCS S Matteo, Pavia, Italy
    Genet Med 9:14-22. 2007
    ..We studied the relationship between the phenotype and genotype in patients with a proven mutation in either ENG (HHT1) or ACVRL1 (HHT2)...
  65. ncbi request reprint Early variations of circulating interleukin-6 and interleukin-10 levels during thoracic radiotherapy are predictive for radiation pneumonitis
    Dominique Arpin
    Department of Pneumology, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69317 Lyon Cedex 04, France
    J Clin Oncol 23:8748-56. 2005
    ....
  66. ncbi request reprint Pulmonary varix mimicking pulmonary arteriovenous malformation in a patient with Turner syndrome
    Jacques Olivier Maillard
    Service de Pneumologie, Centre des Maladies Orphelines Pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, Lyon, France
    Respiration 74:110-3. 2007
    ..Contrast echocardiography may help to distinguish between pulmonary varix and arteriovenous malformation...
  67. ncbi request reprint [Renal AA amyloidosis secondary to bronchiectasis: a report of two cases (including one with Mounier-Kuhn syndrome)]
    C Youakim
    Service de Pneumologie, Hopital Louis Pradel, Lyon, France
    Rev Mal Respir 21:821-4. 2004
    ..We describe 2 patients with AA renal amyloidosis secondary to bronchiectasis (one patient had tracheobronchomegaly or Mounier-Kuhn syndrome)...
  68. ncbi request reprint [Base pulmonary fibrosis associated with summit emphysema: a new clinical entity?]
    V Cottin
    Service de Pneumologie et Centre des maladies orphelines pulmonaires, Hopital Cardiovasculaire et Pneumologique Louis Pradel, Universite Claude Bernard, Lyon, France
    Rev Mal Respir 21:205-6. 2004
  69. ncbi request reprint Mesenchymal cystic hamartoma of the lung in Cowden's disease
    V Cottin
    Service de Pneumologie, Hopital Cardiovasculaire et Pneumologique Louis Pradel, France
    Respir Med 97:188-91. 2003
  70. ncbi request reprint [Opportunistic infections and sarcoidosis]
    N Girard
    Service de Pneumologie Centre des Maladies Orphelines Pulmonaires, Hopital Louis Pradel, Lyon, France
    Rev Mal Respir 21:1083-90. 2004
    ..In spite of CD4+ T-lymphocytopenia and corticosteroids-induced immune suppression, the risk of opportunistic infection is not usually considered to be increased in sarcoidosis...
  71. ncbi request reprint [Pulmonary MALT lymphoma revealing AIDS]
    A B Cortot
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Université de Lyon UMR 754, Lyon, France
    Rev Mal Respir 23:353-7. 2006
    ..We report the case of a patient with an isolated pulmonary mucosa associated lymphoid tissue (MALT) lymphoma that revealed an acquired immune deficiency syndrome (AIDS)...
  72. ncbi request reprint [Rendu-Osler disease]
    Chahera Khouatra
    centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Universite de Lyon
    Rev Prat 58:476. 2008
  73. ncbi request reprint [Diffuse pulmonary diseases]
    V Cottin
    Service de Pneumologie, Hopital Louis Pradel, Universite Claude Bernard, Lyon
    Rev Mal Respir 19:S44-56. 2002
  74. doi request reprint [Unusual pulmonary presentation of lysinuric protein intolerance]
    E Berthoux
    UMR 754 INRA, centre de référence des maladies pulmonaires rares, Hopital Louis Pradel, Hospices Civils de Lyon, Universite de Lyon, Université Lyon I, 69677 Lyon, France
    Rev Mal Respir 27:770-4. 2010
    ..At the age of 25, nocturnal non-invasive ventilation was initiated. Lysinuric protein intolerance is an exceptional genetic cause of interstitial lung disease...
  75. ncbi request reprint [Pulmonary alveolar proteinosis]
    Anne Sophie Blanchet
    Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Université Lyon I, 69677 Lyon
    Rev Prat 55:1865. 2005
  76. ncbi request reprint Chemotherapy is the cornerstone of the combined surgical treatment of lung cancer with synchronous brain metastases
    Nicolas Girard
    Department of Respiratory Medicine, Hopital Louis Pradel, Hospices Civils de Lyon, Lyon, France
    Lung Cancer 53:51-8. 2006
    ..How to manage the primary lung carcinoma remains elusive...
  77. ncbi request reprint Alveolar type II cells isolated from pulmonary adenocarcinoma: a model for JSRV expression in vitro
    Fabienne Archer
    Universite de Lyon, INRA, UMR754, and Department of Respiratory Diseases, Reference Center for Orphan Lung Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, France
    Am J Respir Cell Mol Biol 36:534-40. 2007
    ..This novel experimental model will set up the stage for elucidating lung epithelial transformation in the JSRV-induced tumor...
  78. ncbi request reprint Cough-induced intercostal lung herniation requiring surgery: Report of a case
    Abdulrazzaq Sulaiman
    Department of Thoracic Surgery, Hopital Louis Pradel, 28, avenue du doyen Lepine, 69677, Bron Cedex, France
    Surg Today 36:978-80. 2006
    ..We repaired the herniation by approximating the ribs with heavy stitches. The mechanism of intercostal muscle disruption, and the etiology and treatment of lung herniations, are discussed...
  79. ncbi request reprint [Acute and chronic chest pain]
    Vincent Cottin
    Service de Pneumologie, Hopital Louis Pradel, Universite Claude Bernard, BP Lyon Montchat, 69394 Lyon
    Rev Prat 52:1585-93. 2002
  80. doi request reprint Interstitial lung disease associated with anti-PM/Scl or anti-aminoacyl-tRNA synthetase autoantibodies: a similar condition?
    Jean Christophe Lega
    Department of Respiratory Medicine, Reference Centre for Rare Pulmonary Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, Claude Bernard University Lyon I, University of Lyon, Lyon, France
    J Rheumatol 37:1000-9. 2010
    ..To compare anti-PM/Scl autoantibody-associated interstitial lung disease (ILD) with anti-aminoacyl-tRNA synthetases (anti-ARS) autoantibody-associated ILD...
  81. ncbi request reprint Jaagsiekte Sheep Retrovirus (JSRV): from virus to lung cancer in sheep
    Caroline Leroux
    Universite de Lyon 1, INRA, UMR754, Ecole Nationale Veterinaire de Lyon, IFR 128, F 69007, Lyon, France
    Vet Res 38:211-28. 2007
    ..Activation of the PI3K/Akt and MAPK pathways participates in the envelope-induced transformation. Tumour development is associated with telomerase activation. This review will focus on the induction of cancer by JSRV...
  82. ncbi request reprint [Chronic necrotizing aspergillosis]
    Daniel Cristea
    Hospices Civils de Lyon, Universite de Lyon, Universite Lyon 1, Lyon, France
    Rev Prat 58:1517. 2008
  83. ncbi request reprint [Opacities and intra-thoracic masses]
    Nicolas Girard
    Service de Pneumologie, Hopital Louis Pradel, Hospices Civils de Lyon, Universite Lyon 1, 69677 Lyon Bron Cedex
    Rev Prat 58:767-75. 2008
  84. ncbi request reprint [Saddle nose deformity]
    Marie Coudurier
    centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Universite de Lyon, 69677 Bron
    Rev Prat 57:1863. 2007
  85. ncbi request reprint When to stop in the quest of formes frustes of connective tissue disease?
    Vincent Cottin
    Clin Rheumatol 26:615-6. 2007
  86. ncbi request reprint Pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia: follow-up and pathophysiologic considerations
    Vincent Cottin
    J Vasc Interv Radiol 18:938-9; author reply 939. 2007
  87. ncbi request reprint Combined pulmonary fibrosis and emphysema: an experimental and clinically relevant phenotype
    Vincent Cottin
    Am J Respir Crit Care Med 172:1605; author reply 1605-6. 2005
  88. ncbi request reprint Long-term follow-up in 12 children with pulmonary arteriovenous malformations: confirmation of hereditary hemorrhagic telangiectasia in all cases
    Aurore Curie
    Department of Clinical Genetics and National Reference Centre of Rendu Osler Disease, Hotel Dieu Hospital, Civil Hospices of Lyon, University of Claude Bernard Lyon 1, France
    J Pediatr 151:299-306. 2007
    ..To assess whether pulmonary arteriovenous malformation (PAVM) is associated with hereditary hemorrhagic telangiectasia (HHT)...
  89. ncbi request reprint Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites
    Annemie A Van Linden
    Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Biochemistry 44:6980-9. 2005
    ..These findings support the conclusion that p42(mapk/erk2) promotes extensive phosphorylation of the membrane proximal region in a hierarchical fashion at both consensus and nonconsensus ERK-phosphorylation sites...
  90. ncbi request reprint [Induced interstitial pneumonitis: role of pegylated interferon alpha 2b]
    Pierre Rocca
    Fédération des spécialités digestives, Hopital Edouard Herriot, France
    Gastroenterol Clin Biol 26:405-8. 2002
    ..We discuss the causes of these rare pulmonary alpha-interferon induced complications and the different way to suggest that the pegylated interferon alpha 2b could be related to the risk of pulmonary toxicity of this treatment...
  91. ncbi request reprint Impairment of macrophage survival by NaCl: implications for early pulmonary inflammation in cystic fibrosis
    Gwendolyn S Kerby
    Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Am J Physiol Lung Cell Mol Physiol 283:L188-97. 2002
    ..We speculate that augmentation of macrophage apoptosis in CF airways may result in decreased clearance of neutrophils and in deficiencies in the elimination of common CF pathogens...
  92. ncbi request reprint Ambivalence of CD4 lymphocytopenia in sarcoidosis
    Béatrice Gentil
    Sarcoidosis Vasc Diffuse Lung Dis 20:74-5. 2003
  93. ncbi request reprint Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain
    Vincent Cottin
    Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Immunol 168:4095-102. 2002
    ..Collectively, these findings suggest that in addition to its role in CD120a signaling, an appropriately folded and functionally active DD is required for the localization of the receptor to lipid rafts...