Research Topics
| Th ConrozierSummaryAffiliation: Hospices Civils de Lyon Country: France Publications
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Detail Information
Publications
Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter studyXavier Chevalier
Department of Rheumatology, Hospital Henri Mondor, University Paris XII, Paris, France
J Rheumatol 32:1317-23. 2005..In animal models of OA, IL-1 blockade by IL-1 receptor antagonist (IL-1Ra) can slow the progression of disease. We examined the safety of intraarticular (IA) injections of recombinant human IL-1Ra in patients with knee OA...- Differences in the osteoarthritic synovial fluid composition and rheology between patients with or without flare: a pilot studyThierry Conrozier
Department of Rheumatology, Lyon Sud University Hospital, Pierre Benite, France
Clin Exp Rheumatol 30:729-34. 2012..To study the influence of the inflammatory status (flare or not) on hyaluronic acid (HA) and protein composition and on the intrinsic viscosity of the synoviol fluid (SF) from patients with knee osteoarthritis (KOA)... 
Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategyXavier Chevalier
Department of Rheumatology, University of Paris XII, Henri Mondor Hospital, Bd de Lattre de Tassigny, Creteil 94010, France
Arthritis Res Ther 13:124. 2011..Although these data may suggest cessation of IL-1 therapy in osteoarthritis, other methods such as limited intraarticular anti-IL-1 delivery should still be considered...
Early effect of hyaluronic acid intra-articular injections on serum and urine biomarkers in patients with knee osteoarthritis: An open-label observational prospective studyThierry Conrozier
Rheumatology, Pavillon 2B, Centre Hospitalier Lyon Sud, 165 chemin du grand revoyet 69495, Pierre Benite Cedex, France
J Orthop Res 30:679-85. 2012..This study showed that 90 days after HA IA injections, U-CTX II levels significantly decrease compared to baseline, suggesting a slowdown of type II collagen degradation...- Clinical response to intra-articular injections of hylan G-F 20 in symptomatic hip osteoarthritis: the OMERACT-OARSI criteria applied to the results of a pilot studyThierry Conrozier
Department of Rheumatology, Centre Hospitalier Lyon Sud, 165, Chemin du Grand Revoyet, 69495 Pierre Benite Cedex, France
Joint Bone Spine 73:705-9. 2006..To assess, using the OMERACT-OARSI criteria, the clinical response of patients presenting with symptomatic hip osteoarthritis (OA) to one intra-articular injection of hylan G-F 20... - Differences in biomarkers of type II collagen in atrophic and hypertrophic osteoarthritis of the hip: implications for the differing pathobiologiesT Conrozier
Department of Rheumatology, University Hospital Lyon Sud, Lyon, France
Osteoarthritis Cartilage 15:462-7. 2007..Cartilage serum biomarkers may offer an opportunity to identify such differences in patients... - Prospective, multi-centre, randomised evaluation of the safety and efficacy of five dosing regimens of viscosupplementation with hylan G-F 20 in patients with symptomatic tibio-femoral osteoarthritis: a pilot studyT Conrozier
Department of Rheumatology, Centre Hospitalier Lyon Sud, Pierre Benite, France
Arch Orthop Trauma Surg 129:417-23. 2009..The aim of this study was to assess different dosing regimens of hylan G-F 20, a high molecular-weight cross-linked derivative of HA, in the treatment of pain due to knee OA... - Long-term experience with hylan GF-20 in the treatment of knee osteoarthritisThierry Conrozier
Service de Rhumatologie, Centre Hospitalier Lyon Sud, 165 Chemin du Grand Revoyet, 69495 Pierre Benite Cedex, France
Expert Opin Pharmacother 9:1797-804. 2008..Hylan GF-20 is a cross-linked hyaluronic acid derivative, FDA approved as a medical device since 1997 for the treatment of patients with symptomatic knee osteoarthritis... - Serum concentrations of type II collagen biomarkers (C2C, C1, 2C and CPII) suggest different pathophysiologies in patients with hip osteoarthritisT Conrozier
Department of Rheumatology, University Hospital Lyon Sud, Lyon, France
Clin Exp Rheumatol 26:430-5. 2008..Cartilage biomarkers exist for the measurement of cartilage matrix turnover and may reveal differences in patients with OA... - Safety, efficacy and predictive factors of efficacy of a single intra-articular injection of non-animal-stabilized-hyaluronic-acid in the hip joint: results of a standardized follow-up of patients treated for hip osteoarthritis in daily practiceThierry Conrozier
Department of Rheumatology Pr VIGNON, University Hospital Lyon Sud, Pierre Benite Cedex, France
Arch Orthop Trauma Surg 129:843-8. 2009..To evaluate, in daily clinical practice, the efficacy and tolerability of a single intra-articular injection of non-animal-stabilized hyaluronic acid (NASHA) in patients treated for symptomatic hip OA (HOA)... - Reproducibility and sensitivity to change of a new method of computer measurement of joint space width in hip osteoarthritis. Performance of three radiographic views obtained at a 3-year intervalT Conrozier
Department of Rheumatology, Lyon Sud University Hospital, Pierre Benite, France
Osteoarthritis Cartilage 17:864-70. 2009..A standard radiographic view of the pelvis is commonly used for measurement of hip OA but other views are available... - Is there evidence to support the inclusion of viscosupplementation in the treatment paradigm for patients with hip osteoarthritis?T Conrozier
Department of Rheumatology, Lyon Sud University Hospital, F 69495 Pierre Benite Cedex, France
Clin Exp Rheumatol 23:711-6. 2005..The aim of this study was to review the literature on viscosupplementation as a symptomatic treatment of hip OA... - Epidemiological, clinical, biological and radiological differences between atrophic and hypertrophic patterns of hip osteoarthritis: a case-control studyTh Conrozier
Department of Rheumatology, Centre Hospitalier Lyon Sud, Pierre Benite, France
Clin Exp Rheumatol 22:403-8. 2004..The aim of this study was to determine the epidemiological, radiological and biological differences between the hypertrophic and atrophic forms of hip osteoarthritis... - [Current management of osteoarthritis. Part 1: pharmacological strategies]T Conrozier
Service de Rhumatologie, Centre Hospitalier Lyon Sud, 69495 cedex, Pierre Benite, France
Rev Med Interne 24:183-8. 2003..The place and the modalities of use of the slow-acting symptom modifying drugs remain to be determined more precisely... - Factors predicting long-term efficacy of Hylan GF-20 viscosupplementation in knee osteoarthritisThierry Conrozier
Rheumatology Department, Centre Hospitalier Lyon Sud, 69495 Pierre Benite Cedex, France
Joint Bone Spine 70:128-33. 2003..To describe the long-term effects of Hylan GF-20 viscosupplementation in patients with knee osteoarthritis and to identify factors predicting efficacy... - Intra-articular injections of hylan G-F 20 in patients with symptomatic hip osteoarthritis: an open-label, multicentre, pilot studyT Conrozier
Department of Rheumatology, Centre Hospitalier Lyon Sud, Pierre Benite, France
Clin Exp Rheumatol 21:605-10. 2003..To obtain prospective data on feasibility and safety of intra-articular injections of hylan G-F20 in patients with symptomatic hip osteoarthritis (OA)... - Influence of the quality of tibial plateau alignment on the reproducibility of computer joint space measurement from Lyon schuss radiographic views of the knee in patients with knee osteoarthritisT Conrozier
Service de Rhumatologie, Centre Hospitalier Lyon Sud, Pierre Benite, France
Osteoarthritis Cartilage 12:765-70. 2004..The quality of medial tibial plateau (MT-Plateau) alignment is one of the key elements for accuracy and sensitivity to change of knee radiography in knee osteoarthritis (OA)... - Lyon Schuss radiographic view of the knee. Utility of fluoroscopy for the quality of tibial plateau alignmentThierry Conrozier
Service de Rhumatologie, Centre Hospitalier Lyon Sud, Pierre Benite, France
J Rheumatol 31:584-90. 2004.... - Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss viewsEric Vignon
Claude Bernard University, Lyon, France
Arthritis Rheum 48:378-84. 2003..To evaluate progression of joint space narrowing in radiographs of osteoarthritic (OA) knees imaged in both the standing anteroposterior (AP) and the Lyon schuss positions, using alternative methods to measure joint space width (JSW)... - Comparison of hylan and hyaluronic acid for knee osteoarthritis: comment on the article by Jüni et alXavier Chevalier
Arthritis Rheum 58:1560-1; author reply 1561-2. 2008 - Cross-sectional study of pain and disability at knee replacement surgery for osteoarthritis in 299 patientsFlorence Merle-Vincent
Rheumatology Department, Pavilion 2B, Lyon South Hospital Center, 69495 Pierre Benite, France
Joint Bone Spine 74:612-6. 2007..To evaluate pain and disability at the time of knee replacement surgery for osteoarthritis... - Biological markers for osteoarthritis: an updateXavier Chevalier
Joint Bone Spine 72:106-9. 2005 - Selection of knee radiographs for trials of structure-modifying drugs in patients with knee osteoarthritis: a prospective, longitudinal study of Lyon Schuss knee radiographs with the definition of adequate alignment of the medial tibial plateauThierry Conrozier
Centre Hospitalier Lyon-Sud, , France
Arthritis Rheum 52:1411-7. 2005..To obtain relevant data, only radiographs showing an IMD of </=1.2 mm at both baseline and the end point would have to be analyzed in studies of structure-modifying OA drugs... - Advances in radiographic imaging of progression of hip and knee osteoarthritisEric Vignon
Service de Rheumatologie, Centre Hosptalier Lyon-Sud, France
J Rheumatol 32:1143-5. 2005 - Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis?Kenneth D Brandt
Rheumatology Division, Indiana University School of Medicine, Indianapolis 46202 5100, USA
J Rheumatol 29:1308-20. 2002