C Confavreux

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. ncbi request reprint [Hepatitis B vaccination and multiple sclerosis: where are we?]
    Christian Confavreux
    Service de neurologie A Hôpital neurologique BP Lyon Montchat 69394 Lyon
    Rev Prat 52:2093-5. 2002
  2. ncbi request reprint [Multiple sclerosis]
    Christian Confavreux
    Service neurologie, Hopital Neurologique, 69394 Lyon
    Rev Prat 52:529-38. 2002
  3. ncbi request reprint Natural history of multiple sclerosis: a unifying concept
    Christian Confavreux
    Service de Neurologie A, the European Database for Multiple Sclerosis EDMUS Coordinating Center and INSERM U 433, Hopital Neurologique, Lyon, France
    Brain 129:606-16. 2006
  4. ncbi request reprint Secondary progressive multiple sclerosis: current knowledge and future challenges
    Marco Rovaris
    Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
    Lancet Neurol 5:343-54. 2006
  5. ncbi request reprint [Multiple sclerosis: the new frontier]
    Christian Confavreux
    Service de neurologie A et centre de coordination Edmus et Inserm U433, Hospices Civils de Lyon, Universite Claude Bernard Lyon I, Hopital Neurologique Pierre Wertheimer, 69677 Lyon Bron
    Rev Prat 56:1290-2. 2006
  6. pmc Long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years
    Christian Confavreux
    Hopital Neurologique, Universite Claude Bernard Lyon 1, France
    Mult Scler 18:1278-89. 2012
  7. doi request reprint The clinical epidemiology of multiple sclerosis
    Christian Confavreux
    Service de Neurologie A, Centre de Coordination EDMUS et INSERM U842, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Neuroimaging Clin N Am 18:589-622, ix-x. 2008
  8. ncbi request reprint [Multiple sclerosis: a degenerative disease?]
    Christian Confavreux
    Service de Neurologie A et Centre de Coordination EDMUS sur la sclérose en plaques, INSERM Unité 842, Hospices Civils de Lyon, Universite Lyon 1, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron
    Bull Acad Natl Med 192:483-91; discussion 492-3. 2008
  9. ncbi request reprint [The natural history of multiple sclerosis]
    Christian Confavreux
    Service de Neurologie A, centre de coordination Edmus et Inserm U433, Hopital Neurologique Pierre Wertheimer, 69677 Lyon, Bron
    Rev Prat 56:1313-20. 2006
  10. ncbi request reprint Age at disability milestones in multiple sclerosis
    Christian Confavreux
    The European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique, Hospices Civils de Lyon, Lyon, France
    Brain 129:595-605. 2006

Detail Information

Publications57

  1. ncbi request reprint [Hepatitis B vaccination and multiple sclerosis: where are we?]
    Christian Confavreux
    Service de neurologie A Hôpital neurologique BP Lyon Montchat 69394 Lyon
    Rev Prat 52:2093-5. 2002
  2. ncbi request reprint [Multiple sclerosis]
    Christian Confavreux
    Service neurologie, Hopital Neurologique, 69394 Lyon
    Rev Prat 52:529-38. 2002
  3. ncbi request reprint Natural history of multiple sclerosis: a unifying concept
    Christian Confavreux
    Service de Neurologie A, the European Database for Multiple Sclerosis EDMUS Coordinating Center and INSERM U 433, Hopital Neurologique, Lyon, France
    Brain 129:606-16. 2006
    ....
  4. ncbi request reprint Secondary progressive multiple sclerosis: current knowledge and future challenges
    Marco Rovaris
    Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy
    Lancet Neurol 5:343-54. 2006
    ....
  5. ncbi request reprint [Multiple sclerosis: the new frontier]
    Christian Confavreux
    Service de neurologie A et centre de coordination Edmus et Inserm U433, Hospices Civils de Lyon, Universite Claude Bernard Lyon I, Hopital Neurologique Pierre Wertheimer, 69677 Lyon Bron
    Rev Prat 56:1290-2. 2006
  6. pmc Long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years
    Christian Confavreux
    Hopital Neurologique, Universite Claude Bernard Lyon 1, France
    Mult Scler 18:1278-89. 2012
    ....
  7. doi request reprint The clinical epidemiology of multiple sclerosis
    Christian Confavreux
    Service de Neurologie A, Centre de Coordination EDMUS et INSERM U842, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Neuroimaging Clin N Am 18:589-622, ix-x. 2008
    ..Precise, consistent, and reliable data from appropriate cohorts have become available and knowledge is fairly comprehensive...
  8. ncbi request reprint [Multiple sclerosis: a degenerative disease?]
    Christian Confavreux
    Service de Neurologie A et Centre de Coordination EDMUS sur la sclérose en plaques, INSERM Unité 842, Hospices Civils de Lyon, Universite Lyon 1, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron
    Bull Acad Natl Med 192:483-91; discussion 492-3. 2008
    ..It will also be necessary to extinguish the slow-burning diffuse inflammation nested in the central nervous system behind the blood-brain barrier. This is the new therapeutic challenge in MS...
  9. ncbi request reprint [The natural history of multiple sclerosis]
    Christian Confavreux
    Service de Neurologie A, centre de coordination Edmus et Inserm U433, Hopital Neurologique Pierre Wertheimer, 69677 Lyon, Bron
    Rev Prat 56:1313-20. 2006
    ..In spite of the outstanding clinical polymorphism of MS, a unifying concept of the disease ("complexity vs heterogeneity") can be put forward...
  10. ncbi request reprint Age at disability milestones in multiple sclerosis
    Christian Confavreux
    The European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique, Hospices Civils de Lyon, Lyon, France
    Brain 129:595-605. 2006
    ..Aside acute focal recurrent inflammation and diffuse chronic neurodegeneration, accelerated ageing-related mechanisms may operate in the central nervous system of multiple sclerosis patients...
  11. ncbi request reprint Accumulation of irreversible disability in multiple sclerosis: from epidemiology to treatment
    Christian Confavreux
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex 03, France
    Clin Neurol Neurosurg 108:327-32. 2006
    ....
  12. ncbi request reprint Non-specific immunosuppressants in the treatment of multiple sclerosis
    Christian Confavreux
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Clin Neurol Neurosurg 106:263-9. 2004
    ....
  13. ncbi request reprint Intravenous immunoglobulins, pregnancy and multiple sclerosis
    Christian Confavreux
    European Database for Multiple Sclerosis EDMUS Coordinating Center, Service de Neurologie A, INSERM U433, Hopital Neurologique Pierre Wertheimer, Lyon, France
    J Neurol 251:1138-9. 2004
  14. ncbi request reprint Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process
    Christian Confavreux
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Lyon, France
    Brain 126:770-82. 2003
    ..Early assessable clinical variables significantly influence the time from the onset of multiple sclerosis to the assignment of a disability score of 4, but not the subsequent progression of irreversible disability...
  15. ncbi request reprint Natural history of multiple sclerosis: implications for counselling and therapy
    Christian Confavreux
    INSERM U 433, Service of Neurology A and EDMUS Coordinating Centre, Hopital Neurologique, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Curr Opin Neurol 15:257-66. 2002
    ..Thus multiple sclerosis should be considered to be as much neurodegenerative as inflammatory and disease-modifying therapeutic strategies should be reconsidered by focusing on protection and repair of the nervous system...
  16. ncbi request reprint [Diagnostic criteria of different clinical forms ]
    C Confavreux
    Centre de Coordination Européen EDMUS European Database for MUltiple Sclerosis sur la Sclérose en Plaques, Service de Neurologie A, Hopital Neurologique, 59, bd Pinel, 69003 Lyon, France
    Rev Neurol (Paris) 157:907-13. 2001
    ..Time will say whether this new classification will replace the previous one...
  17. doi request reprint Multiple sclerosis and epileptic seizures
    H Catenoix
    Service de Neurologie Fonctionnelle et d Epileptologie, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France
    Mult Scler 17:96-102. 2011
    ..The association between epilepsy and multiple sclerosis (MS) is not a coincidence...
  18. ncbi request reprint [Multiple sclerosis and pregnancy]
    S Vukusic
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59, boulevard Pinel, 69677 Bron Cedex
    Rev Neurol (Paris) 162:299-309. 2006
    ..The preventive effect of progesterone combined with estradiol on post partum relapses will be tested in a large-scale randomized and placebo-controlled European trial, the POPART'MUS study...
  19. doi request reprint The Prevention of Post-Partum Relapses with Progestin and Estradiol in Multiple Sclerosis (POPART'MUS) trial: rationale, objectives and state of advancement
    S Vukusic
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron F 69677, France
    J Neurol Sci 286:114-8. 2009
    ..The trial is registered under the reference NTC00127075...
  20. doi request reprint Reliability of longitudinal brain volume loss measurements between 2 sites in patients with multiple sclerosis: comparison of 7 quantification techniques
    F Durand-Dubief
    Service de Neurologie A et Fondation Eugène Devic EDMUS pour la Sclérose en Plaques, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Bron Cedex, France
    AJNR Am J Neuroradiol 33:1918-24. 2012
    ..Therefore, the purpose of this work was to assess the robustness of 7 different postprocessing algorithms applied to images acquired from different MR imaging systems...
  21. ncbi request reprint [Multiple sclerosis: spontaneous course, natural history]
    S Vukusic
    Service du Neurologie A, Pr Ch Confavreux, Hôpital Neurologique Pierre Wertheimer 59, boulevard Pinel, 69003 Lyon, France
    Rev Neurol (Paris) 157:753-6. 2001
    ..At the present time early prediction of outcome remains impossible. In the near future, new imaging techniques may provide a solution to this problem allowing selection of patients at risk who could benefit from early treatment...
  22. doi request reprint Mycophenolate mofetil may be effective in CNS sarcoidosis but not in sarcoid myopathy
    G Androdias
    Department of Neurology A, Hopital Neurologique, Hospices Civils de Lyon, France
    Neurology 76:1168-72. 2011
    ..To describe effectiveness, steroid-sparing effect, and tolerance of the antiproliferative immunosuppressant mycophenolate mofetil (MMF) in neurosarcoidosis...
  23. doi request reprint The natural history of multiple sclerosis with childhood onset
    Christel Renoux
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France
    Clin Neurol Neurosurg 110:897-904. 2008
    ....
  24. doi request reprint NMO-IgG and Devic's neuromyelitis optica: a French experience
    Romain Marignier
    Service de Neurologie A and EDMUS Co ordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 59 boulevard Pinel Lyon Bron cedex, F 69677, France
    Mult Scler 14:440-5. 2008
    ..Our objectives were to replicate the test and to assess its usefulness...
  25. pmc Regional variations in the prevalence of multiple sclerosis in French farmers
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    J Neurol Neurosurg Psychiatry 78:707-9. 2007
    ..Studies on the prevalence of multiple sclerosis have been carried out worldwide, showing a heterogeneous distribution between countries and even between the different regions of the same country...
  26. ncbi request reprint Prognostic factors for progression of disability in the secondary progressive phase of multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyon Cedex 03, 69394, France
    J Neurol Sci 206:135-7. 2003
    ..We review here information available from the literature and from the Lyon MS database about this secondary progressive phase...
  27. ncbi request reprint Primary and secondary progressive multiple sclerosis
    Sandra Vukusic
    European Database for Multiple Sclerosis EDMUS Coordinating Center and Service de Neurologie A, Hopital Neurologique, Hospices Civils de Lyon, 59 Boulevard Pinel, Lyons Cedex 03, 69394, France
    J Neurol Sci 206:153-5. 2003
    ..A clue to this question could be the comparison between the different MS subtypes with a progressive phase. We discuss here the clinical similarities and differences between secondary and primary progressive MS...
  28. ncbi request reprint [Cytoimmunological profile of cerebrospinal fluid in diagnosis of multiple sclerosis]
    Christiane Caudie
    Fédération de biologie, service d immunologie et de neuro immunologie, Hopital Neurologique et Neurochirurgical Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron, France
    Pathol Biol (Paris) 53:68-74. 2005
    ..65 x 10(-2)), IgG index for intrathecal synthesis of IgG is increased in 69% (N < 0.70), sensitive detection of oligoclonal IgG restricted to CSF by isoelectric focusing is positive in 91% (86-96%) with a specificity of 96% (93-99%)...
  29. ncbi request reprint Natural history of multiple sclerosis: risk factors and prognostic indicators
    Sandra Vukusic
    Service de Neurologie A and EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    Curr Opin Neurol 20:269-74. 2007
    ..To highlight progress in the description of the natural course and prognosis of multiple sclerosis...
  30. doi request reprint [Devic's neuromyelitis optica and related neurological disorders]
    Romain Marignier
    Service de Neurologie A, EDMUS Coordinating Center, Hopital Neurologique Pierre Wertheimer, 69677 Lyon Bron Cedex, France
    Presse Med 39:371-80. 2010
    ..Finally, NMO-IgG, which seems to be directly pathogenic, might be a clue for a better understanding of intimate DNMO immunopathology...
  31. doi request reprint [Natural history of multiple sclerosis]
    Sandra Vukusic
    Service de Neurologie A, centre de coordination EDMUS pour la sclérose en plaques, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69677 Bron Cedex, France
    Presse Med 39:359-62. 2010
    ..Recent studies suggest that the clinical phenotype of MS is mostly age-related and that relapses play a minimal role in the long-term accumulation of disability...
  32. ncbi request reprint Pregnancy and multiple sclerosis: the children of PRIMS
    Sandra Vukusic
    The European Database for Multiple Sclerosis Coordinating Center and Service de Neurologie A, INSERM U 433, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69677 Lyon Bron Cedex, France
    Clin Neurol Neurosurg 108:266-70. 2006
    ..The preventive effect of progesterone combined with estradiol on post partum relapses is about to be tested in a large randomized and placebo-controlled European trial, the POPART'MUS study...
  33. ncbi request reprint Pregnancy and multiple sclerosis (the PRIMS study): clinical predictors of post-partum relapse
    Sandra Vukusic
    Service de Neurologie A, Hopital Neurologique Pierre Wertheimer, 59 Boulevard Pinel, 69394 Lyon Cedex 03, France
    Brain 127:1353-60. 2004
    ..This is, however, not sufficient to identify in advance women with multiple sclerosis who are more likely to relapse, especially for planning therapeutic trials aiming to prevent post-partum relapses...
  34. ncbi request reprint Natural history of multiple sclerosis with childhood onset
    Christel Renoux
    Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France
    N Engl J Med 356:2603-13. 2007
    ..The course and prognosis of childhood-onset multiple sclerosis have not been well described...
  35. doi request reprint Primary angiitis of the central nervous system: response to mycophenolate mofetil
    F Chenevier
    Service de Neurologie A and the European Database for Multiple Sclerosis Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Lyon Bron Cedex, France
    J Neurol Neurosurg Psychiatry 80:1159-61. 2009
    ..Successful treatment with mycophenolate mofetil in combination with steroids is described...
  36. ncbi request reprint Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment
    X Perrot
    Department of Neurology A, Hopital Neurologique, Hospices Civils de Lyon, France
    Neurology 67:2256-8. 2006
    ..An important common feature was that, in seven cases, symptomatology occurred within 2 hours of first telithromycin intake--notably in cases of severe exacerbation...
  37. doi request reprint Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords
    Geraldine Androdias
    National Institute for Medical Research U842, Lyon, France
    Ann Neurol 68:465-76. 2010
    ..In the present paper, we sought to determine whether such a link could be similarly demonstrated in the spinal cord of patients with progressive MS...
  38. doi request reprint Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury
    Romain Marignier
    Service de Neurologie A and EDMUS Coordinating Centre, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France
    Brain 133:2578-91. 2010
    ..These mechanisms could add to the complement-induced damage, particularly the demyelination, seen in vivo...
  39. doi request reprint Uveitis associated with multiple sclerosis
    Julie Le Scanff
    Department of Internal Medicine, Hospices Civils de Lyon, Hotel Dieu, 1 Place de l Hopital, 69288 Lyon Cedex 02, France
    Mult Scler 14:415-7. 2008
    ..The topography and timing of uveitis were not associated with any significant difference in MS course and prognosis. There was no difference in the course and prognosis in patients with or without uveitis...
  40. doi request reprint Metabotropic glutamate receptor type 1 autoantibody-associated cerebellitis: a primary autoimmune disease?
    Romain Marignier
    Service de Neurologie A and European Database for Multiple Sclerosis Coordinating Center, Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, 69677 Lyon Bron Cedex, France
    Arch Neurol 67:627-30. 2010
    ....
  41. ncbi request reprint Mismatch negativity (MMN) in multiple sclerosis: an event-related potentials study in 46 patients
    Julien Jung
    Department of Clinical Neurophysiology, Hopital Neurologique, Lyon, France
    Clin Neurophysiol 117:85-93. 2006
    ..To assess pre-attentive detection mechanisms indexed by MMN component of auditory Event-Related Potentials (ERPs) in Multiple Sclerosis (MS) patients...
  42. ncbi request reprint [Multiple sclerosis (MS), an inflammatory or degenerative disease?]
    Christian Confavreux
    Presse Med 33:151-2. 2004
  43. ncbi request reprint MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood
    Yann Mikaeloff
    Service de Neurologie Pediatrique, CHU, Angers, France
    Brain 127:1942-7. 2004
    ..Their low sensitivity, however, shows that this prediction remains difficult...
  44. ncbi request reprint Steroid hormones in multiple sclerosis
    Martine El-Etr
    INSERM U 488, Le Kremlin Bicetre, France
    J Neurol Sci 233:49-54. 2005
    ..These clinical and experimental data have led to consider sexual steroids as potential therapeutic tools for preventing relapses in women with MS, in particular in the post-partum period...
  45. ncbi request reprint First episode of acute CNS inflammatory demyelination in childhood: prognostic factors for multiple sclerosis and disability
    Yann Mikaeloff
    Service de Neurologie Pediatrique, Hopital Roger Salengro, Lille, France
    J Pediatr 144:246-52. 2004
    ..To evaluate prognostic factors for second attack and for disability in children presenting with an initial episode of central nervous system (CNS) demyelination...
  46. ncbi request reprint Natalizumab plus interferon beta-1a for relapsing multiple sclerosis
    Richard A Rudick
    Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    N Engl J Med 354:911-23. 2006
    ..Despite interferon beta therapy, many patients have relapses. Natalizumab, an alpha4 integrin antagonist, appeared to be safe and effective alone and when added to interferon beta-1a in preliminary studies...
  47. ncbi request reprint [Etiology of multiple sclerosis]
    David Axel Laplaud
    Service de Neurologie, INSERM U643, CIC de neurologie, CHU de Nantes, Hôpital G et R Laënnec, 44093 Nantes 01
    Rev Prat 56:1306-12. 2006
    ..However, it appears, on the basis of recent findings, that multiple sclerosis is not only a disease of the immune system but also implies specific neurobiological factors which must be determined in studies to come...
  48. ncbi request reprint Health-related quality of life in multiple sclerosis: effects of natalizumab
    Richard A Rudick
    Department of Neurology, Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Ann Neurol 62:335-46. 2007
    ..To report the relationship between disease activity and health-related quality of life (HRQoL) in relapsing multiple sclerosis, and the impact of natalizumab...
  49. ncbi request reprint "Absolute" quantification in magnetic resonance spectroscopy: validation of a clinical protocol in multiple sclerosis
    Matthieu Bagory
    Creatis LRMN, CNRS UMR 5220 and INSERM U630, Universite de Lyon, 69621 Villeurbanne, France
    Conf Proc IEEE Eng Med Biol Soc 2007:3458-61. 2007
    ..This "absolute" quantification method was applied to patients with Multiple Sclerosis (MS). The results show a significant decrease in both N-Acetyl Aspartate (NAA) and choline concentrations...
  50. ncbi request reprint [New frontiers in multiple sclerosis]
    Christian Confavreux
    Presse Med 37:77-9. 2008
  51. ncbi request reprint [Hepatitis B vaccination and multiple sclerosis]
    Christian Confavreux
    Presse Med 34:1205-8. 2005
  52. ncbi request reprint [Contribution of nuclear magnetic resonance imaging in multiple sclerosis]
    Jean Philippe Ranjeva
    Centre d exploration du métabolisme par résonance magnétique, UMR CNRS 6612, CHU Timone, 13005 Marseille
    Rev Prat 56:1326-35. 2006
    ..They lead to new approaches for analysing the pathophysiological processes at work in MS and their course in time...
  53. ncbi request reprint [Multiple sclerosis: positive diagnosis]
    Jerome De Seze
    Clinique Neurologique, Hopital Civil, 67091 Strasbourg
    Rev Prat 56:1321-5. 2006
    ..The recently proposed criteria for MS include MRI data as a possible definition of this dissemination. These new criteria make possible a very early diagnosis of MS...
  54. ncbi request reprint [Myasthenia]
    Francoise Bouhour
    Service de pathologies neuromusculaires, Hopital Neurologique Pierre Wertheimer, 69394 Lyon
    Rev Prat 55:1927-32. 2005
  55. ncbi request reprint European validation of a standardized clinical description of multiple sclerosis
    Maria Pia Amato
    Department of Neurological Sciences, University of Florence, Viale Morgagni, 85, 50134, Florence, Italy
    J Neurol 251:1472-80. 2004
    ....
  56. ncbi request reprint Infections and the risk of relapse in multiple sclerosis
    Christian Confavreux
    Brain 125:933-4. 2002
  57. ncbi request reprint Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum
    Giovanni Stevanin
    INSERM, UMR679, Federal Institute for Neuroscience Research, Pitie Salpetriere Hospital, Paris, France
    Nat Genet 39:366-72. 2007
    ..The identification of the function of the gene will provide insight into the mechanisms leading to the degeneration of the corticospinal tract and other brain structures in this frequent form of ARHSP...