Pierre Cochat

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. pmc Growth after renal transplantation
    Jérôme Harambat
    Département de Pédiatrie and Inserm U820, Hôpital Edouard Herriot and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Nephrol 24:1297-306. 2009
  2. ncbi request reprint Primary hyperoxaluria type 1: practical and ethical issues
    Pierre Cochat
    Centre de référence des maladies rénales rares and EPICIME, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Nephrol 28:2273-81. 2013
  3. pmc Reduced elastogenesis: a clue to the arteriosclerosis and emphysematous changes in Schimke immuno-osseous dysplasia?
    Marie Morimoto
    Provincial Medical Genetics Program, Department of Medical Genetics, Children s and Women s Health Centre of BC, 4500 Oak Street, Room C234, Vancouver, BC, V6H 3N1, Canada
    Orphanet J Rare Dis 7:70. 2012
  4. doi request reprint Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment
    Pierre Cochat
    Reference Center for Rare Renal Diseases and EPICIME, Department of Paediatrics, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Nephrol Dial Transplant 27:1729-36. 2012
  5. pmc Takayasu arteritis in children
    Safia Al Abrawi
    Departement de Pediatrie, Hôpital Edouard Herriot and Université Claude Bernard Lyon1, Lyon, France
    Pediatr Rheumatol Online J 6:17. 2008
  6. doi request reprint [Primary hyperoxaluria]
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, Hospices Civils de Lyon, 59, boulevard Pinel, 69677 Bron Cedex, France
    Nephrol Ther 7:249-59. 2011
  7. ncbi request reprint [Paediatric nephrology in developing countries]
    P Cochat
    Departement de Pediatrie, Hopital Edouard Herriot, 5, Place d Arsonval, 69437 Lyon Cedex 03, France Université Claude Bernard, Lyon, France
    Arch Pediatr 12:723-5. 2005
  8. pmc Disease recurrence in paediatric renal transplantation
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, INSERM U, Hôpital Femme Mère Enfant and Université de Lyon, Bron, France
    Pediatr Nephrol 24:2097-108. 2009
  9. doi request reprint Primary hyperoxaluria type 1: strategy for organ transplantation
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon, France
    Curr Opin Organ Transplant 15:590-3. 2010
  10. ncbi request reprint [Aging with chronic renal failure from childhood]
    P Cochat
    Departement de Pediatrie, INSERM U499, Centre de Référence des Maladies Rénales Héréditaires, Hopital Edouard Herriot, Universite Claude Bernard, Lyon, France
    Arch Pediatr 13:609-11. 2006

Detail Information

Publications96

  1. pmc Growth after renal transplantation
    Jérôme Harambat
    Département de Pédiatrie and Inserm U820, Hôpital Edouard Herriot and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Nephrol 24:1297-306. 2009
    ....
  2. ncbi request reprint Primary hyperoxaluria type 1: practical and ethical issues
    Pierre Cochat
    Centre de référence des maladies rénales rares and EPICIME, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Nephrol 28:2273-81. 2013
    ....
  3. pmc Reduced elastogenesis: a clue to the arteriosclerosis and emphysematous changes in Schimke immuno-osseous dysplasia?
    Marie Morimoto
    Provincial Medical Genetics Program, Department of Medical Genetics, Children s and Women s Health Centre of BC, 4500 Oak Street, Room C234, Vancouver, BC, V6H 3N1, Canada
    Orphanet J Rare Dis 7:70. 2012
    ..However, the mechanism by which the vascular and pulmonary disease arises in SIOD remains unknown...
  4. doi request reprint Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment
    Pierre Cochat
    Reference Center for Rare Renal Diseases and EPICIME, Department of Paediatrics, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Nephrol Dial Transplant 27:1729-36. 2012
    ..In chronic kidney disease Stages 4 and 5, the best outcomes to date were achieved with combined liver-kidney transplantation...
  5. pmc Takayasu arteritis in children
    Safia Al Abrawi
    Departement de Pediatrie, Hôpital Edouard Herriot and Université Claude Bernard Lyon1, Lyon, France
    Pediatr Rheumatol Online J 6:17. 2008
    ..Surgery was required in two patients. Follow-up ranged from 3 to 10 years since diagnosis. In three cases antihypertensive drugs and methotrexate were stopped, and prednisone was reduced to 7.5 mg/day...
  6. doi request reprint [Primary hyperoxaluria]
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, Hospices Civils de Lyon, 59, boulevard Pinel, 69677 Bron Cedex, France
    Nephrol Ther 7:249-59. 2011
    ..In the future, primary hyperoxaluria type 1 may benefit from hepatocyte transplantation, chaperone molecules, etc...
  7. ncbi request reprint [Paediatric nephrology in developing countries]
    P Cochat
    Departement de Pediatrie, Hopital Edouard Herriot, 5, Place d Arsonval, 69437 Lyon Cedex 03, France Université Claude Bernard, Lyon, France
    Arch Pediatr 12:723-5. 2005
  8. pmc Disease recurrence in paediatric renal transplantation
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, INSERM U, Hôpital Femme Mère Enfant and Université de Lyon, Bron, France
    Pediatr Nephrol 24:2097-108. 2009
    ..In the near future the issue of DR after kidney Tx may benefit from alternatives to organ Tx, such as recombinant proteins, specific monoclonal antibodies, cell/gene therapy, and chaperone molecules...
  9. doi request reprint Primary hyperoxaluria type 1: strategy for organ transplantation
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon, France
    Curr Opin Organ Transplant 15:590-3. 2010
    ..As glomerular filtration rate decreases due to progressive renal involvement, oxalate accumulates and results in systemic oxalosis...
  10. ncbi request reprint [Aging with chronic renal failure from childhood]
    P Cochat
    Departement de Pediatrie, INSERM U499, Centre de Référence des Maladies Rénales Héréditaires, Hopital Edouard Herriot, Universite Claude Bernard, Lyon, France
    Arch Pediatr 13:609-11. 2006
  11. doi request reprint Survey of first-year medical students to assess their knowledge and attitudes toward organ transplantation and donation
    D Mekahli
    Département de Pédiatrie and Centre de Référence des Maladies Rénales Rares, Hôpital Edouard Herriot and Université Lyon 1, Lyon, France
    Transplant Proc 41:634-8. 2009
    ..The aim of this survey was to evaluate the level of knowledge of medical students and their gaps about organ donation prior to any medical course...
  12. ncbi request reprint Primary hyperoxaluria type 1: still challenging!
    Pierre Cochat
    Centre de Référence des Maladies Rénales Héréditaires, Hopital Edouard Herriot, Lyon, France
    Pediatr Nephrol 21:1075-81. 2006
    ..Aggressive dialysis therapies are required to avoid progressive oxalate deposition in established end-stage renal disease (ESRD), and minimization of the time on dialysis will improve both the patient's quality of life and survival...
  13. ncbi request reprint [Current management of Fabry disease]
    Pierre Cochat
    Centre de Référence des Maladies Rénales Héréditaires, Hopital Edouard Herriot, Lyon, France
    Nephrol Ther 2:S167-71. 2006
    ..Such a treatment is safe and efficient but its biweekly intravenous administration is still uncomfortable, so that further alternative therapeutic approaches may be encouraged...
  14. ncbi request reprint [Pediatric nephrology in developing countries]
    P Cochat
    Service de pédiatrie et centre de référence des maladies rénales rares, Hôpitalfemme mère enfant et Université Lyon 1, Lyon, France
    Med Trop (Mars) 69:543-7. 2009
    ..The improvement in the care of renal children therefore requires better medical knowledge, nurse training and population information...
  15. ncbi request reprint [Living-donor kidney transplantation in children]
    Pierre Cochat
    Departement de Pediatrie, Hopital Edouard Herriot, université Lyon Lyon cedex, France
    Nephrol Ther 4:77-80. 2008
    ..In the medical evaluation of the donor, specific explorations, such as the search of a genetic mutation, could be necessary in the case of hereditary renal disease...
  16. doi request reprint Maximizing growth in children after renal transplantation
    Pierre Cochat
    Service de Pediatrie, Centre de Référence des Maladies Rénales Rares and Inserm U820, Hospices Civils de Lyon and Université de Lyon, Lyon, France
    Transplantation 88:1321-2. 2009
    ....
  17. pmc Nephrolithiasis related to inborn metabolic diseases
    Pierre Cochat
    Centre de Référence des Maladies Rénales Rares and Inserm U820, Hospices Civils de Lyon and Université de Lyon, Lyon, France
    Pediatr Nephrol 25:415-24. 2010
    ..Compliance is a major issue regarding the progression of renal damage, but the overall outcome mainly depends on extra-renal involvement in relation to the metabolic defect...
  18. ncbi request reprint [What is new in pediatric nephrology?]
    P Cochat
    Centre de Référence des Maladies Rénales Héréditaires, département de pédiatrie et Inserm U499, hôpital Edouard Herriot et université Claude Bernard, Lyon, France
    Arch Pediatr 13:64-8. 2006
    ..In addition, a large number of epidemiological studies and clinical trials have allowed guidelines and recommendations to be provided for chronic and end-stage renal failure, urinary tract infection, glomerular diseases, etc...
  19. ncbi request reprint Renal outcome of children exposed to cyclosporine in utero
    P Cochat
    Departement de Pediatrie, Hôpital Edouard Herriot and Université Claude Bernard, Lyon, France
    Transplant Proc 36:208S-210S. 2004
    ..However further studies based on large series are required in order to demonstrate that renal fetal effects have limited clinical consequences...
  20. ncbi request reprint [Organ transplantation in children]
    P Cochat
    Departement de Pediatrie, INSERM U499, Hopital Edouard Herriot, Universite Claude Bernard, 69437 Lyon Cedex 03, France
    Arch Pediatr 11:529-31. 2004
  21. ncbi request reprint [Management of acute bronchiolitis in infants]
    A Bourrillon
    Service de Pediatrie Generale, Hopital Robert Debre, 48, boulevard Serurier, 75019 Paris, France
    Arch Pediatr 11:709-11. 2004
  22. ncbi request reprint [Causes of apparent life threatening events in infants: questions, exams, investigations for clinical use]
    P Foucaud
    Service de pédiatrie néonatologie, Centre Hospitalier de Versailles, Hopital Andre Mignot, 177, rue de Versailles, 78157 Le Chesnay Cedex, France
    Arch Pediatr 11:700-2. 2004
  23. ncbi request reprint [Use of procalcitonin at the pediatric emergency room]
    D Gendrel
    Hopital Saint Vincent de Paul, Paris, France
    Arch Pediatr 11:582-4. 2004
  24. ncbi request reprint [Post-traumatic anorexia: challenging multidisciplinary management]
    M Paradis-Guennou
    Service de médecine psychologique enfants adolescents, Hopital Saint Eloi, 34295 Montpellier cedex 05, France
    Arch Pediatr 11:607-9. 2004
  25. ncbi request reprint [Urinary infections in children. Leukocyturia]
    Pierre Cochat
    Département de pédiatrie Hôpital Edouard Herriot and Université Claude Bernard 69437 Lyon
    Rev Prat 53:571-5. 2003
  26. doi request reprint What about the renal function during childhood of children born from dialysed mothers?
    Pauline Abou-Jaoude
    Service de Néphrologie et Rhumatologie Pédiatriques, Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, Bron, France
    Nephrol Dial Transplant 27:2365-9. 2012
    ..e. exposure to uraemic toxins, therapies, intermittent haemodynamic changes during sessions, prematurity, growth retardation)...
  27. doi request reprint Long-term critical issues in pediatric renal transplant recipients: a single-center experience
    Jérôme Harambat
    Service de néphrologie et rhumatologie pédiatrique, Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, Hospices Civils de Lyon, Bron, France
    Transpl Int 26:154-61. 2013
    ..Excellent long-term outcomes can be achieved in pediatric renal Tx, but specific problems such as malignancies, growth, and social outcome remain challenging...
  28. doi request reprint Renal function in pediatric liver transplantation: a long-term follow-up study
    Jérôme Harambat
    Service de pédiatrie et centre de référence des maladies rénales rares, Hospices Civils de Lyon et Université Claude Bernard Lyon 1, Lyon, France
    Transplantation 86:1028-34. 2008
    ..The purpose of this study was to determine incidence, determinants, and progression of long-term chronic renal insufficiency (CRI) in a single-center series of pediatric liver transplant recipients...
  29. pmc Which creatinine and cystatin C equations can be reliably used in children?
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques Hôpital Femme Mère Enfant, boulevard Pinel, 69677 Bron Cedex, France
    Clin J Am Soc Nephrol 6:552-60. 2011
    ....
  30. doi request reprint Hyperuricemia after liver transplantation in children
    Jérôme Harambat
    Service de Pédiatrie et Centre de références des Maladies Rénales Rares, Hopital Edouard Herriot, Hospices Civils de Lyon et Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Transplant 12:847-53. 2008
    ..Hyperuricemia after liver transplantation in children is a frequent problem which needs further investigation...
  31. doi request reprint Genotype-phenotype correlation in primary hyperoxaluria type 1: the p.Gly170Arg AGXT mutation is associated with a better outcome
    Jérôme Harambat
    Service de Pediatrie, Centre de Référence des Maladies Rénales Rares du Sud Ouest, Centre Hospitalier Universitaire, Bordeaux, France
    Kidney Int 77:443-9. 2010
    ..Our results underscore the severe prognosis of primary hyperoxaluria type 1 and the necessity for early diagnosis and treatment, as well as confirm a better prognosis of the p.Gly170Arg mutation...
  32. doi request reprint Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients
    Wei Zhao
    Department of Pediatric Pharmacology and Pharmacogenetics, Hopital Robert Debre, Paris, France
    J Clin Pharmacol 50:1280-91. 2010
    ..Body weight, concomitant medication, and UGT2B7 genotype contribute significantly to the interindividual variability of MMF disposition in pediatric renal-transplant patients...
  33. doi request reprint GFR estimation in adolescents and young adults
    Luciano Selistre
    Exploration Fonctionnelle Rénale et Métabolique Pavillon P, Hopital Edouard Herriot, 5 Place d Arsonval, Lyon Cedex 03, France
    J Am Soc Nephrol 23:989-96. 2012
    ..In conclusion, we recommend the use of pediatric equations to estimate GFR from childhood to early adulthood...
  34. ncbi request reprint Recurrence of nephrotic syndrome after renal transplantation: influence of increased immunosuppression
    Sylvie Nathanson
    Pediatric Nephrology Unit, Hopital Armand Trousseau, Paris, France
    Pediatr Nephrol 20:1801-4. 2005
    ....
  35. doi request reprint Long-term effects of cyclophosphamide therapy in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome
    Benoit Cammas
    Centre Hospitalier Universitaire de Bordeaux, Service de Pediatrie, Centre de référence Maladies Rénales Rares du Sud Ouest, Bordeaux, France
    Nephrol Dial Transplant 26:178-84. 2011
    ..Little is known about prognostic factors in SDNS and FRNS treated by CYP. The objectives of this study are to determine long-term outcomes and factors associated with sustained remission in these patients...
  36. doi request reprint Long-term results of rhGH treatment in children with renal failure: experience of the French Society of Pediatric Nephrology
    Etienne Berard
    Service de Pediatrie, CHU de Nice, Hopital de l Archet 2, Nice, France
    Pediatr Nephrol 23:2031-8. 2008
    ..Early rhGH administration during CT gives better height SDS at both the end of rhGH therapy and in adulthood...
  37. doi request reprint The influence of glomerular filtration rate and age on fibroblast growth factor 23 serum levels in pediatric chronic kidney disease
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, boulevard Pinel, 69677 Bron Cedex, France
    J Clin Endocrinol Metab 95:1741-8. 2010
    ..Although its importance in chronic kidney disease (CKD) has been demonstrated in adults, there is little information in pediatric patients...
  38. doi request reprint Both extrauterine and intrauterine growth restriction impair renal function in children born very preterm
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, Bron Cedex, France
    Kidney Int 76:445-52. 2009
    ..Extrauterine growth restriction represents a new risk factor for long-term renal impairment in premature children...
  39. doi request reprint Early renal abnormalities in children with postnatally diagnosed autosomal dominant polycystic kidney disease
    Luciano Selistre
    Exploration Fonctionnelle Rénale et Métabolique, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France
    Pediatr Nephrol 27:1589-93. 2012
    ..However, previous studies pointed out renal-related anomalies which may benefit from early appropriate treatments. This study was conducted to evaluate the prevalence and severity of early renal dysfunction in ADPKD children...
  40. doi request reprint Long-lasting extracorporeal albumin dialysis in a child with end-stage renal disease and severe cholestasis
    Etienne Javouhey
    Service d urgences et de réanimation pédiatriques, Hopital Edouard Herriot, Hospices Civils de Lyon, 5 Place d Arsonval, Lyon, France
    Pediatr Transplant 13:235-9. 2009
    ..Long-lasting MARS dialysis is feasible in children, decreases adverse effects of severe chronic cholestasis, and may help to preserve nutritional status prior to combined liver-kidney transplantation...
  41. doi request reprint Bone metabolism in oxalosis: a single-center study using new imaging techniques and biomarkers
    Justine Bacchetta
    Service de Néphrologie et Rhumatologie Pédiatriques, Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, 59 Bd Pinel, 69677 Bron, France
    Pediatr Nephrol 25:1081-9. 2010
    ....
  42. ncbi request reprint Switch from cyclosporine A to mycophenolate mofetil in nephrotic children
    Tim Ulinski
    Department of Pediatrics, Nephrology Unit, Hopital Edouard Herriot, 69437 Lyon Cedex 03, France
    Pediatr Nephrol 20:482-5. 2005
    ..Interruption of CyA treatment lead to rapid amelioration of kidney function in these children, often associated with steroid sparing, which may lead to additional benefit for growth velocity, blood pressure and physical appearance...
  43. pmc Schwartz formula: is one k-coefficient adequate for all children?
    Vandrea Carla De Souza
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hospices Civils de Lyon, Lyon, France
    PLoS ONE 7:e53439. 2012
    ..5 for all patients). We reevaluated the coefficient of the 2009-Schwartz formula according to sex and age in a pediatric population...
  44. pmc The consequences of chronic kidney disease on bone metabolism and growth in children
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, Bron, France
    Nephrol Dial Transplant 27:3063-71. 2012
    ..The aim of this review is to provide an overview of the mineral, bone and vascular abnormalities associated with CKD in children in terms of pathophysiology, diagnosis and clinical management...
  45. doi request reprint Malignancy incidence after renal transplantation in children: a 20-year single-centre experience
    Foteini Koukourgianni
    Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant et Université de Lyon, Lyon, France
    Nephrol Dial Transplant 25:611-6. 2010
    ..The pattern of malignancies that occur in the paediatric graft population is different from that in the general paediatric population and in the population of adult organ transplant recipients...
  46. doi request reprint Effect of conservative treatment on the renal outcome of children with primary hyperoxaluria type 1
    Sonia Fargue
    Service de Pediatrie, Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon and Université Lyon 1, Lyon, France
    Kidney Int 76:767-73. 2009
    ..7 per year. Our study strongly suggests that early and aggressive conservative management may preserve renal function of compliant children with this disorder, thereby avoiding dialysis and postponing transplantation...
  47. doi request reprint Congenital versus acquired solitary kidney: is the difference relevant?
    Pauline Abou Jaoude
    Service de Nephrologie Pediatrique, Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant Université de Lyon, Lyon, France
    Nephrol Dial Transplant 26:2188-94. 2011
    ..The aim of the study was to assess mid- and long-term outcome of children with SK, with special highlight on the differential functional outcome of congenital and acquired forms of SK...
  48. doi request reprint Recurrence of a dysgerminoma in Frasier syndrome
    Guillaume Mestrallet
    Service de Pédiatrie and Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon, Hôpital Femme Mère Enfant and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Transplant 15:e53-5. 2011
    ..We report on a patient followed for FS revealed by acute peritoneal syndrome because of ovarian dysgerminoma. Therapeutic options had led to an unusual course with recurrent neoplastic disease after renal transplantation...
  49. doi request reprint Deferasirox-induced renal impairment in children: an increasing concern for pediatricians
    Laurence Dubourg
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, Hospices Civils de Lyon, Bron, France
    Pediatr Nephrol 27:2115-22. 2012
    ..The aim of this study was to evaluate tubular and glomerular function before and after the initiation of DFX therapy in a pediatric patient population...
  50. doi request reprint HHV-6 infection in a pediatric kidney transplant patient
    Foteini Koukourgianni
    Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant and Université Lyon 1, Bron Cedex, France
    Pediatr Nephrol 24:2445-8. 2009
    ..The patient had a successful recovery without specific treatment. This case report highlights the wide spectrum of complications resulting from HHV-6 infection in immunosuppressed patients...
  51. pmc Uric acid and IGF1 as possible determinants of FGF23 metabolism in children with normal renal function
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, 59 Bd Pinel, 69677, Bron, France
    Pediatr Nephrol 27:1131-8. 2012
    ..Although circulating values of FGF23 are increased in early chronic kidney disease (CKD), the interplay between FGF23 levels, growth and nutritional biomarkers has not been evaluated in children with normal renal function...
  52. pmc Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: phenotype-genotype correlation and outcome in 32 patients with CLDN16 or CLDN19 mutations
    Astrid Godron
    Département de génétique, Hopital Europeen Georges Pompidou, Paris, France
    Clin J Am Soc Nephrol 7:801-9. 2012
    ..The objectives of this study were to describe the clinical and genetic features of familial hypomagnesemia with hypercalciuria and nephrocalcinosis and analyze phenotype-genotype associations in patients with CLDN16 or CLDN19 mutations...
  53. doi request reprint Cysteamine therapy delays the progression of nephropathic cystinosis in late adolescents and adults
    Albane Brodin-Sartorius
    Department of Nephrology, Necker Enfants Malades Hospital, Paris, France
    Kidney Int 81:179-89. 2012
    ..Thus, cysteamine decreases and delays the onset of complications and improves life expectancy in cystinosis. Hence, cysteamine therapy should be introduced as early as possible during childhood and maintained lifelong...
  54. doi request reprint Bone assessment in children with chronic kidney disease: data from two new bone imaging techniques in a single-center pilot study
    Justine Bacchetta
    Service de Néphrologie et Rhumatologie Pédiatriques, Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, 59 Bd Pinel, 69677, Bron, France
    Pediatr Nephrol 26:587-95. 2011
    ..Novel bone imaging techniques seem feasible in children, and further longitudinal studies are required to thoroughly explore long-term cardiovascular and bone consequences of phosphate-calcium metabolism deregulation during CKD...
  55. doi request reprint Influence of age at disease onset in the outcome of paediatric systemic lupus erythematosus
    Elodie Descloux
    Service de Medecine Interne, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France
    Rheumatology (Oxford) 48:779-84. 2009
    ..The aim of this study was to investigate the influence of age at disease onset in the outcome of paediatric SLE (pSLE)...
  56. doi request reprint [Kidney transplantation in childhood: from milimeter to centimeters]
    Bruno Ranchin
    Service de Nephrologie Pediatrique, Hopital Femme Mere Enfant, Hospices Civils de Lyon et Université de Lyon
    Nephrol Ther 7:604-7. 2011
    ..Normal growth is a major objective of the management of transplanted children. The mean final height increased during the 20 last years to be between -1.63 and -0.92 SDS depending on age and period of the transplantation...
  57. doi request reprint Long-term outcome of idiopathic steroid-resistant nephrotic syndrome: a multicenter study
    Djalila Mekahli
    Service de Pediatrie, Centre de Référence des Maladies Rénales Rares, Hôpital Femme Mère Enfant and Université de Lyon, Lyon, France
    Pediatr Nephrol 24:1525-32. 2009
    ..Further prospective controlled trials will delineate the potential benefit of new immunosuppressive treatment...
  58. doi request reprint 'Renal hypersensitivity' to inulin and IgA nephropathy
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Hospices Civils de Lyon et Université Lyon 1, Lyon, France
    Pediatr Nephrol 23:1883-5. 2008
    ..We can hypothesize that inulin had activated the innate immune system. Inulin may, thus, have been the initiating event of the renal relapse, acting like an infection, in a patient with IgA-mediated immunological dysregulation...
  59. ncbi request reprint Hypertensive crisis, hepatitis B virus and polyarteritis nodosa in a child
    Alexandre Belot
    Nephrologie Pediatrique, Hopital Edouard Herriot, Lyon, France
    Pediatr Nephrol 22:97-100. 2007
    ..Nine years later, he had no sign of PAN, normal blood pressure and normal renal function in the absence of any treatment...
  60. doi request reprint Familial nephrogenic syndrome of inappropriate antidiuresis: dissociation between aquaporin-2 and vasopressin excretion
    Bruno Ranchin
    Centre de Réfé rence des Maladies Rénales Rares, Hospices Civils de Lyon, 69317 Lyon, France
    J Clin Endocrinol Metab 95:E37-43. 2010
    ....
  61. ncbi request reprint Triamcinolone acetonide: a new management of noncompliance in nephrotic children
    Tim Ulinski
    Department of Pediatrics, Hopital Edouard Herriot, Lyon, France
    Pediatr Nephrol 20:759-62. 2005
    ..Patients who do not benefit from the TA can be classified as very probably steroid-dependent. TA seems to be a useful therapeutic strategy in those patients for whom noncompliance is strongly suspected...
  62. doi request reprint Mutations of NPHP2 and NPHP3 in infantile nephronophthisis
    Kalman Tory
    INSERM, Paris, France
    Kidney Int 75:839-47. 2009
    ..We show that NPHP3 mutations in both infantile and adolescent nephronophthisis point to a common pathophysiological mechanism despite their different clinical presentations...
  63. doi request reprint Non-drug-induced nephrotoxicity
    Justine Bacchetta
    Centre de Référence des Maladies Rénales Rares, Service de Néphrologie et Rhumatologie Pédiatriques, Hopital Femme Mere Enfant, boulevard Pinel, 69677 Bron, France
    Pediatr Nephrol 24:2291-300. 2009
    ..Nephrotoxicity should be considered when there is any unexplained renal impairment, especially in children...
  64. doi request reprint Precocious puberty and unlicensed paediatric drugs for severe hyperparathyroidism
    Justine Bacchetta
    Service de Néphrologie et Rhumatologie Pédiatriques, Centre de Référence des Maladies Rénales Rares, Hopital Femme Mere Enfant, Bron, France
    Nephrol Dial Transplant 24:2595-8. 2009
    ..Monitoring of plasma testosterone in patients receiving unlicensed paediatric drugs for managing hyperparathyroidism and presenting with a change in genitals is therefore recommended...
  65. ncbi request reprint Maternal isodisomy of the telomeric end of chromosome 2 is responsible for a case of primary hyperoxaluria type 1
    Françoise Chevalier-Porst
    Biochimie Pédiatrique, Hopital Debrousse, Lyon, France
    Am J Med Genet A 132:80-3. 2005
    ..Quantitative PCR of AGXT exons 1 and 3 on the patient's and parents genomic DNA revealed the presence of two copies of the gene. This is the first case of PH1 caused by segmental maternal isodisomy of 2q37.3...
  66. doi request reprint Pseudohypoaldosteronisms, report on a 10-patient series
    Alexandre Belot
    Departement de Pediatrie, Hopital Edouard Herriot, 69437 Lyon Cedex 03, France
    Nephrol Dial Transplant 23:1636-41. 2008
    ..Autosomal recessive and dominant hereditary forms are caused by Epithelial Na Channel and Mineralocorticoid Receptor mutation respectively, while secondary PHA1 is usually associated with urological problems...
  67. pmc Decisions concerning potentially life-sustaining treatments in paediatric nephrology: a multicentre study in French-speaking countries
    Isabelle Fauriel
    Laboratoire d éthique médicale, de droit de la santé et de santé publique, Faculte de Medecine Necker, Paris, France
    Nephrol Dial Transplant 19:1252-7. 2004
    ..The aim of this work was to evaluate such practices in all nephrology centres in French-speaking European countries, so that guidelines could be discussed and drawn up by professionals...
  68. pmc Primary hyperoxaluria
    Jérôme Harambat
    Service de Pediatrie, Centre de référence Maladies Rénales Rares du Sud Ouest, Centre Hospitalier Universitaire de Bordeaux, 33076 Bordeaux, France
    Int J Nephrol 2011:864580. 2011
    ..In end-stage renal disease patients, the best outcomes have been achieved with combined liver-kidney transplantation which corrects the enzyme defect...
  69. doi request reprint Pediatric en bloc kidney transplantation into pediatric recipients: the French experience
    Mickael Afanetti
    Department of Pediatric Nephrology, Hôpitaux pédiatriques de Nice CHU Lenval et Université de Nice Sophia Antipolis, Nice, France
    Pediatr Transplant 16:183-6. 2012
    ..Median glomerular filtration rate at three months, one, five, and 10 yr was 90.8, 106, 87.8, and 66.1 mL/1.73 m(2) /min. We believe that en bloc transplantation may be an option for children with end-stage kidney disease...
  70. ncbi request reprint Neonatal hemolytic uremic syndrome after mother-to-child transmission of Escherichia coli O157
    Tim Ulinski
    Department of Pediatrics, Hopital Edouard Herriot, 3 Place d Arsonval, 69437 Lyon Cedex 03, France
    Pediatr Nephrol 20:1334-5. 2005
    ..E. coli 0157:H7 and SLT 2 were detected in the stool. SLT 2 was also found in the mother's stool. This is the first report of mother-to-child transmission of SLT-producing E. coli...
  71. ncbi request reprint Long-term follow-up of metachronous marrow-kidney transplantation in severe type II sialidosis: what does success mean?
    Manuel Schiff
    Hopital Edouard Herriot, Pediatrics, Centre de référence Maladies Héréditaires du Métabolisme, Lyon, France
    Nephrol Dial Transplant 20:2563-5. 2005
  72. ncbi request reprint Transient hyperphosphatasemia after organ transplantation in children
    Bruno Ranchin
    Department of Pediatrics, Edouard Herriot Hospital, Lyon, France
    Pediatr Transplant 6:308-12. 2002
    ..Hence, an isolated increase in the serum alkaline phosphatase level following transplantation should not be of concern in this population of patients...
  73. ncbi request reprint [Renal transplantation techniques in children with impaired patency of the inferior vena cava or iliac vein]
    Lionel Badet
    Service de Chirurgie et de la Transplantation et d Urologie, Hopital Edouard Herriot, Lyon, France
    Prog Urol 15:285-90. 2005
    ..More generally, they also discuss the available technical options based on a review of the literature...
  74. doi request reprint Nephronophthisis-like nephritis associated with fibrous dysplasia of bone
    Justine Bacchetta
    Departement de Pediatrie, Centre de Référence des Maladies Rénales Rares, Hôpital Edouard Herriot and Université Claude Bernard Lyon 1, Lyon, France
    Pediatr Nephrol 23:1559-63. 2008
    ..However, a fortuitous association between these two conditions is also possible...
  75. doi request reprint Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
    Agnes Doreau
    Universite de Lyon, Institut Fédératif de Recherche 128, Lyon, France
    Nat Immunol 10:778-85. 2009
    ....
  76. doi request reprint Phenotype-genotype correlation in antenatal and neonatal variants of Bartter syndrome
    Karine Brochard
    Hopitaux de Toulouse, Université Paul Sabathier, Departement de Pediatrie, Centre de Référence des Maladies Rénales Rares, Toulouse F31000, France
    Nephrol Dial Transplant 24:1455-64. 2009
    ..Our aim was to study the frequency, clinical characteristics and outcome of each genetic subtype...
  77. ncbi request reprint Skin cancers following pediatric organ transplantation
    Sylvie Euvrard
    Dermatology Department, Hopital Edouard Herriott, Lyon, France
    Dermatol Surg 30:616-21. 2004
    ..Although several studies have been devoted to adult transplant patients, few data are available on the long-term skin malignancies following pediatric organ transplantation...
  78. ncbi request reprint Munchausen syndrome by proxy with massive proteinuria and gastrointestinal hemorrhage
    Tim Ulinski
    Department of Pediatrics, Hopital Edouard Herriot, 3 Place d Arsonval, 69437 Lyon Cedex 03, France
    Pediatr Nephrol 19:798-800. 2004
    ..These were all negative for protein. The mother, who was a nurse, finally confessed to adding human albumin to the urine samples...
  79. ncbi request reprint Fatal neurologic involvement in pediatric Wegener's granulomatosis
    Tim Ulinski
    Department of Pediatrics, Hopital Edouard Herriot, Lyon, France
    Pediatr Neurol 32:278-81. 2005
    ..This case emphasizes the need for activity scores to identify patients at risk for progressive systemic vasculitis requiring early and long-term aggressive immunosuppressive therapy...
  80. doi request reprint Paraneoplastic glomerular diseases and malignancies
    Justine Bacchetta
    Reference Centre for Rare Renla Diseases, Hopital Femme Mere Enfant, Bron F 69600, France
    Crit Rev Oncol Hematol 70:39-58. 2009
    ..Thus, epidemiologic and mechanistic studies are needed to determine the true prevalence of paraneoplastic glomerulopathies and investigate new pathophysiologic approaches...
  81. ncbi request reprint Better long-term functional adaptation to the child's size with pediatric compared to adult kidney donors
    Laurence Dubourg
    Departement de Pediatrie, Service d Exploration Fonctionnelle Rénale et Métabolique, Hôpital Edouard Herriot and Université Claude Bernard, INSERM U 499, Faculte Laennec, Lyon, France
    Kidney Int 62:1454-60. 2002
    ....
  82. ncbi request reprint Bilateral urinary calculi after treatment with a silicate-containing milk thickener
    Tim Ulinski
    Department of Paediatrics, Hopital Edouard Herriot, 3, Place d Arsonval, 69437 Lyon Cedex 03, France
    Eur J Pediatr 163:239-40. 2004
    ..After replacement of the silicate-containing agent by a silicate-free milk thickener, the lesions were completely reversible as confirmed by repeated renal ultrasound examinations over a 2-month period...
  83. ncbi request reprint Four-year follow-up of oral health surveillance in renal transplant children
    Pierre Farge
    Departement de Pediatrie, Hopital Edouard Herriot, 69437 Lyon, France
    Pediatr Nephrol 21:851-5. 2006
    ..Twenty-one demands originated from the parents. Over a 4-year period the attendance of a dental specialist resulted in a significant improvement in the oral health of the renal transplant children...
  84. doi request reprint European best practice quo vadis? From European Best Practice Guidelines (EBPG) to European Renal Best Practice (ERBP)
    Carmine Zoccali
    Nephrol Dial Transplant 23:2162-6. 2008
    ..The present publication reviews the arguments based on which this decision was taken...
  85. pmc Decision making concerning life-sustaining treatment in paediatric nephrology: professionals' experiences and values
    Isabelle Fauriel
    laboratoire d éthique médicale et de médecine légale, Faculté de médecine de Paris 5, 45 Rue des Saints Peres, 75006 Paris, France
    Nephrol Dial Transplant 20:2746-50. 2005
    ..The second paper deals exclusively with the interviews with doctors and analyses their lifetime's experience and perception...
  86. ncbi request reprint A report of the Lisbon Conference on the care of the kidney transplant recipient
    Mario Abbud-Filho
    Instituto de Urologia e Nefrologia and Medical School FAMERP, Sao Jose do Rio Preto SP, Brazil
    Transplantation 83:S1-22. 2007
  87. ncbi request reprint Longitudinal growth in children following kidney transplantation: from conservative to pharmacological strategies
    Tim Ulinski
    Department of Pediatric Nephrology and INSERM U515, Hopital Trousseau, AP HP, Universite Paris VI, 26, avenue du Docteur Arnold Netter, 75012 Paris, France
    Pediatr Nephrol 21:903-9. 2006
    ..As long as corticosteroids are believed to be essential after renal Tx, rhGH should be considered to optimize longitudinal growth in children...
  88. ncbi request reprint Current management of infants with fetal renal pelvis dilation: a survey by French-speaking pediatric nephrologists and urologists
    Khalid Ismaili
    Department of Perinatal and Pediatric Nephrology, Hopital Universitaire des Enfants Reine Fabiola, Brussels, Belgium
    Pediatr Nephrol 19:966-71. 2004
    ..The variability in attitudes is most probably due to the absence of clear guidelines based on prospective and controlled trials...
  89. ncbi request reprint A multicenter, open-label, pharmacokinetic/pharmacodynamic safety, and tolerability study of basiliximab (Simulect) in pediatric de novo renal transplant recipients
    Gisela Offner
    Kinderklinik der Medizinische Hochschule, Hannover, Germany
    Transplantation 74:961-6. 2002
    ..We report on the safety and preliminary efficacy of basiliximab in pediatric de novo renal transplant recipients...
  90. ncbi request reprint A rational dosing algorithm for basiliximab (Simulect) in pediatric renal transplantation based on pharmacokinetic-dynamic evaluations
    John M Kovarik
    Novartis Pharmaceuticals, Basel, Switzerland
    Transplantation 74:966-71. 2002
    ..The pharmacokinetics and immunodynamics of basiliximab were assessed in 39 pediatric de novo kidney allograft recipients to rationally chose a dose regimen for this age group...
  91. ncbi request reprint A cluster of mutations in the UMOD gene causes familial juvenile hyperuricemic nephropathy with abnormal expression of uromodulin
    Karin Dahan
    Universite Catholique de Louvain, Center for Human Genetics, Brussels, Belgium
    J Am Soc Nephrol 14:2883-93. 2003
    ..Mutations in UMOD may critically affect the function of uromodulin, resulting in abnormal accumulation within tubular cells and reduced urinary excretion...
  92. ncbi request reprint Is decreased bone mineral density in pediatric transplant recipients really a problem?
    Janusz Feber
    Pediatr Transplant 7:342-4. 2003
  93. ncbi request reprint Genetic investigation of autosomal recessive distal renal tubular acidosis: evidence for early sensorineural hearing loss associated with mutations in the ATP6V0A4 gene
    Rosa Vargas-Poussou
    Centre Hospitalier Universitaire de Rouen, Département de Pédiatrie Médicale, and Faculté de Médecine et de Pharmacie, Rouen, France
    J Am Soc Nephrol 17:1437-43. 2006
    ..The data also demonstrate that mutations in either of these genes may cause early deafness, and they highlight the importance of genetic screening for recessive forms of dRTA independent of hearing status...
  94. ncbi request reprint Body growth after combined liver-kidney transplantation in children with primary hyperoxaluria type 1
    Richard Nissel
    Department of Pediatric Nephrology, Charite Children s Hospital, Berlin, Germany
    Transplantation 82:48-54. 2006
    ..Combined liver and kidney transplantation (LKT) corrects the underlying metabolic defect and restores renal function in these children...
  95. ncbi request reprint The challenge of renal function in heart transplant children
    Sylvie Di Filippo
    Department of Pediatric Cardiology, Hopital Cardiologique de Lyon, 28 Avenue Doyen Lepine, 69677, Bron Cedex, France
    Pediatr Nephrol 22:333-42. 2007
    ..Of high interest is the impact of genetic polymorphism on the development of renal dysfunction...
  96. ncbi request reprint IgACE: a placebo-controlled, randomized trial of angiotensin-converting enzyme inhibitors in children and young people with IgA nephropathy and moderate proteinuria
    Rosanna Coppo
    Nephrology, Dialysis and Transplantation Unit, Regina Margherita University Hospital, 10127 Turin, Italy
    J Am Soc Nephrol 18:1880-8. 2007
    ....