Alexis Arzimanoglou

Summary

Affiliation: Hospices Civils de Lyon
Country: France

Publications

  1. doi request reprint Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy IDEE, University Hospitals of Lyon and INSERM U821, Lyon, France
    Lancet Neurol 8:82-93. 2009
  2. ncbi request reprint Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
  3. doi request reprint GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction
    Gaetan Lesca
    Department of Genetics, University Hospitals of Lyon, Lyon, France
    Nat Genet 45:1061-6. 2013
  4. doi request reprint Dravet syndrome: from electroclinical characteristics to molecular biology
    Alexis Arzimanoglou
    Epilepsy, Sleep and Pediatric Neurophysiology Department, Institute for Children and Adolescents with Epilepsy IDEE, University Hospitals of Lyon, Lyon, France
    Epilepsia 50:3-9. 2009
  5. doi request reprint Epileptic encephalopathies of the Landau-Kleffner and continuous spike and waves during slow-wave sleep types: genomic dissection makes the link with autism
    Gaetan Lesca
    Department of Constitutional Cytogenetics, Lyon Hospices Civils, Lyon, France
    Epilepsia 53:1526-38. 2012
  6. pmc Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    PLoS Med 5:e166. 2008
  7. doi request reprint All children who experience epileptic falls do not necessarily have Lennox-Gastaut syndrome... but many do
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy IDEE, University Hospital of Lyon HCL Lyon, France
    Epileptic Disord 13:S3-13. 2011
  8. doi request reprint Evidence of a non-progressive course of alternating hemiplegia of childhood: study of a large cohort of children and adults
    Eleni Panagiotakaki
    Institute for Children and Adolescents with Epilepsy IDEE, Hopital Femme Mere Enfant, University Hospitals of Lyon HCL, France
    Brain 133:3598-610. 2010
  9. doi request reprint The evolution of antiepileptic drug development and regulation
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy, Epilepsy, Sleep and Paediatric Neurophysiology Department, University Hospitals of Lyon HCL and Inserm U821, Lyon, France
    Epileptic Disord 12:3-15. 2010
  10. doi request reprint Outcome and prognosis of status epilepticus in children
    Karine Ostrowsky
    Institute for Children and Adolescents with Epilepsy IDEE and Paediatric Neurophysiology, University Hospitals of Lyon, Hopital Femme Mere Enfant, Lyon, France
    Semin Pediatr Neurol 17:195-200. 2010

Collaborators

Detail Information

Publications12

  1. doi request reprint Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy IDEE, University Hospitals of Lyon and INSERM U821, Lyon, France
    Lancet Neurol 8:82-93. 2009
    ..We also suggest key considerations for future trials and highlight the importance of a comprehensive approach to the assessment and management of this syndrome...
  2. ncbi request reprint Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
    ....
  3. doi request reprint GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction
    Gaetan Lesca
    Department of Genetics, University Hospitals of Lyon, Lyon, France
    Nat Genet 45:1061-6. 2013
    ..The identification of GRIN2A as a major gene for these epileptic encephalopathies provides crucial insights into the underlying pathophysiology. ..
  4. doi request reprint Dravet syndrome: from electroclinical characteristics to molecular biology
    Alexis Arzimanoglou
    Epilepsy, Sleep and Pediatric Neurophysiology Department, Institute for Children and Adolescents with Epilepsy IDEE, University Hospitals of Lyon, Lyon, France
    Epilepsia 50:3-9. 2009
    ..However, the defining characteristics of seizure type and EEG patterns initially identified by Dravet remain fundamental to diagnosis...
  5. doi request reprint Epileptic encephalopathies of the Landau-Kleffner and continuous spike and waves during slow-wave sleep types: genomic dissection makes the link with autism
    Gaetan Lesca
    Department of Constitutional Cytogenetics, Lyon Hospices Civils, Lyon, France
    Epilepsia 53:1526-38. 2012
    ..A role for autoimmunity has been proposed but the pathophysiology of CSWSS and of LKS remains uncharacterized...
  6. pmc Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    PLoS Med 5:e166. 2008
    ....
  7. doi request reprint All children who experience epileptic falls do not necessarily have Lennox-Gastaut syndrome... but many do
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy IDEE, University Hospital of Lyon HCL Lyon, France
    Epileptic Disord 13:S3-13. 2011
    ..Effective management of LGS requires regular reappraisal of the evolving symptoms and features, and adjustment of the treatment accordingly...
  8. doi request reprint Evidence of a non-progressive course of alternating hemiplegia of childhood: study of a large cohort of children and adults
    Eleni Panagiotakaki
    Institute for Children and Adolescents with Epilepsy IDEE, Hopital Femme Mere Enfant, University Hospitals of Lyon HCL, France
    Brain 133:3598-610. 2010
    ....
  9. doi request reprint The evolution of antiepileptic drug development and regulation
    Alexis Arzimanoglou
    Institute for Children and Adolescents with Epilepsy, Epilepsy, Sleep and Paediatric Neurophysiology Department, University Hospitals of Lyon HCL and Inserm U821, Lyon, France
    Epileptic Disord 12:3-15. 2010
    ..Alongside these changes in approach, the modern era has witnessed important advances in antiepileptic drugs themselves, either through development of novel molecules, or targeted, structural improvements of older agents...
  10. doi request reprint Outcome and prognosis of status epilepticus in children
    Karine Ostrowsky
    Institute for Children and Adolescents with Epilepsy IDEE and Paediatric Neurophysiology, University Hospitals of Lyon, Hopital Femme Mere Enfant, Lyon, France
    Semin Pediatr Neurol 17:195-200. 2010
    ..Future studies will need to address some of these methodological issues to provide the best information when discussing outcome with the family members of children with status epilepticus...
  11. doi request reprint A novel three base-pair LGI1 deletion leading to loss of function in a family with autosomal dominant lateral temporal epilepsy and migraine-like episodes
    Julitta de Bellescize
    Service Epilepsie, sommeil, Explorations Fonctionnelles Neurolopédiatriques et CTRS IDEE, Hopital Femme Mere Enfant, Hospices Civils de Lyon, Lyon, France
    Epilepsy Res 85:118-22. 2009
    ..Functional studies showed that the mutated protein was not secreted when transfected in COS cells, consistent with a causative role in the disease...
  12. ncbi request reprint Positron emission tomography in epileptogenic hypothalamic hamartomas
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Neurology Hospital, Lyon, France
    Epileptic Disord 5:219-27. 2003
    ..Whether these cortical abnormalities only reflect the propagation of ictal discharges, or a potentially independent seizure onset zone remains unknown...