J J Lefrere

Summary

Affiliation: Hopital Foch
Country: France

Publications

  1. ncbi Natural history of the TT virus infection through follow-up of TTV DNA-positive multiple-transfused patients
    J J Lefrere
    Institut National de la Transfusion Sanguine, and Faculté Saint Antoine, Université Pierre et Marie Curie 75012 Paris, France
    Blood 95:347-51. 2000
  2. ncbi The risk of disease progression is determined during the first year of human immunodeficiency virus type 1 infection
    J J Lefrere
    Institut National de la Transfusion Sanguine Laboratoire de Virologie, Hopital Saint Antoine, Paris, France
    J Infect Dis 177:1541-8. 1998
  3. ncbi Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons
    J J Lefrere
    Institut National de la Transfusion Sanguine, 75012 Paris, France
    J Infect Dis 179:783-9. 1999
  4. ncbi Plasma human immunodeficiency virus RNA below 40 Copies/mL is rare in untreated persons even in the first years of infection
    J J Lefrere
    Institut National de la Transfusion Sanguine, 75012 Paris, France
    J Infect Dis 180:526-9. 1999
  5. ncbi Screening for HBV, HCV and HIV genomes in blood donations: shortcomings of pooling revealed by a multicentre study simulating real-time testing
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 80:33-44. 1999
  6. ncbi GBV-C/hepatitis G virus (HGV) RNA load in immunodeficient individuals and in immunocompetent individuals
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    J Med Virol 59:32-7. 1999
  7. ncbi [Human T-lymphotropic virus type I (HTLV-I): risk of transmission with transfusion]
    J J Lefrere
    Unité de Recherches biocliniques et transfusionnelles, Institut National de la Transfusion Sanguine, Paris
    Presse Med 29:1134-8. 2000
  8. ncbi Natural history of GBV-C/hepatitis G virus infection through the follow-up of GBV-C/hepatitis G virus-infected blood donors and recipients studied by RNA polymerase chain reaction and anti-E2 serology
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    Blood 90:3776-80. 1997
  9. ncbi Lessons from a multicentre study of the detectability of viral genomes based on a two-round quality control of GB virus C (GBV-C)/hepatitis G virus (HGV) polymerase chain reaction assay
    J J Lefrere
    Unité de recherches biocliniques, Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 85:117-24. 2000
  10. doi [Genetic diversity of human erythroviruses. Consequences on infectious safety of plasma derivatives]
    A Servant-Delmas
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
    Transfus Clin Biol 16:482-8. 2009

Detail Information

Publications22

  1. ncbi Natural history of the TT virus infection through follow-up of TTV DNA-positive multiple-transfused patients
    J J Lefrere
    Institut National de la Transfusion Sanguine, and Faculté Saint Antoine, Université Pierre et Marie Curie 75012 Paris, France
    Blood 95:347-51. 2000
    ..The prevalence of TTV DNA observed in blood recipients is consistent with that of TTV infection observed in blood donors. TTV infection frequently tends to persist. (Blood. 2000;95:347-351)..
  2. ncbi The risk of disease progression is determined during the first year of human immunodeficiency virus type 1 infection
    J J Lefrere
    Institut National de la Transfusion Sanguine Laboratoire de Virologie, Hopital Saint Antoine, Paris, France
    J Infect Dis 177:1541-8. 1998
    ..Baseline HIV RNA load was a CD4+ T cell-independent predictor of progression to death. The major finding was that the disease outcome for HIV-1-infected persons is already determined during the first year of infection...
  3. ncbi Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons
    J J Lefrere
    Institut National de la Transfusion Sanguine, 75012 Paris, France
    J Infect Dis 179:783-9. 1999
    ..The carriage of GBV-C/HGV RNA is associated with a slower progression of HIV disease in coinfected persons...
  4. ncbi Plasma human immunodeficiency virus RNA below 40 Copies/mL is rare in untreated persons even in the first years of infection
    J J Lefrere
    Institut National de la Transfusion Sanguine, 75012 Paris, France
    J Infect Dis 180:526-9. 1999
    ..Such data confirm the general trend of disease progression in the entire population of HIV carriers...
  5. ncbi Screening for HBV, HCV and HIV genomes in blood donations: shortcomings of pooling revealed by a multicentre study simulating real-time testing
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 80:33-44. 1999
    ..The improvement and standardization of assays needs to be attained, and training of laboratories appears to be a step crucial for routine screening of viral genomes in blood donations...
  6. ncbi GBV-C/hepatitis G virus (HGV) RNA load in immunodeficient individuals and in immunocompetent individuals
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    J Med Virol 59:32-7. 1999
    ....
  7. ncbi [Human T-lymphotropic virus type I (HTLV-I): risk of transmission with transfusion]
    J J Lefrere
    Unité de Recherches biocliniques et transfusionnelles, Institut National de la Transfusion Sanguine, Paris
    Presse Med 29:1134-8. 2000
    ....
  8. ncbi Natural history of GBV-C/hepatitis G virus infection through the follow-up of GBV-C/hepatitis G virus-infected blood donors and recipients studied by RNA polymerase chain reaction and anti-E2 serology
    J J Lefrere
    Institut National de la Transfusion Sanguine, Paris, France
    Blood 90:3776-80. 1997
    ..7 months. The persistent infection rate was 100% in this donor cohort. Once acquired, the infection to GBV-C/HGV generally tends to persist in immunocompetent patients...
  9. ncbi Lessons from a multicentre study of the detectability of viral genomes based on a two-round quality control of GB virus C (GBV-C)/hepatitis G virus (HGV) polymerase chain reaction assay
    J J Lefrere
    Unité de recherches biocliniques, Institut National de la Transfusion Sanguine, Paris, France
    J Virol Methods 85:117-24. 2000
    ....
  10. doi [Genetic diversity of human erythroviruses. Consequences on infectious safety of plasma derivatives]
    A Servant-Delmas
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
    Transfus Clin Biol 16:482-8. 2009
    ..Recently, a new human parvovirus (PARV4) has been discovered. The consequences on blood transfusion of this blood-borne agent and its pathogenicity are still unknown...
  11. doi HIV-1 DNA for the measurement of the HIV reservoir is predictive of disease progression in seroconverters whatever the mode of result expression is
    Véronique Avettand-Fenoel
    AP HP, CHU Necker Enfants Malades, Laboratoire de Virologie, Paris, France
    J Clin Virol 42:399-404. 2008
    ..Previously, HIV-DNA levels have sometimes been reported by other means: copies/10(6) CD4(+)T cells, reflecting the proportion of infected cells; or copies/mL whole blood, reflecting the global blood reservoir size...
  12. ncbi [Safety of blood products and B19 parvovirus]
    J J Lefrere
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75709 Paris cedex 15, France
    Transfus Clin Biol 13:235-41. 2006
    ..If not, a screening of blood donors positive for B19 IgG would be a sufficient preventive measure...
  13. ncbi [The BOTIA project ("Blood and Organ Transmissible Infectious Agents"): a European collection of blood samples and an observatory of agents transmitted by blood transfusion or organ transplantation]
    J J Lefrere
    Département des Agents Transmissibles par le Sang, Institut National de la Transfusion Sanguine, Paris, France
    Transfus Clin Biol 12:93-4. 2005
  14. ncbi [Discussions about Europe]
    J J Lefrere
    Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75739 Paris cedex 15, France
    Transfus Clin Biol 11:257-9. 2004
  15. doi [Doctor Brown-Sequard's therapy]
    J J Lefrere
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris, France
    Ann Endocrinol (Paris) 71:69-75. 2010
    ..He even had followers in the following century, amongst whom Serge Voronoff (1866-1951), who grafted monkey testicles in replacement of human ones, or Paul Niehans (1882-1971) who practiced therapy using calf embryo cells in Switzerland...
  16. pmc [Teaching transfusion medicine research in the francophone world]
    J J Lefrere
    Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
    Transfus Clin Biol 16:427-30. 2009
    ..As part of the course, each student develops a study protocol that can be implemented in his/her blood center of hospital...
  17. ncbi [In memory of Jean-Pierre Soulier, the writer]
    J J Lefrere
    Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015, Paris, France
    Transfus Clin Biol 11:71-3. 2004
  18. ncbi [Electronic learning: interactive learning in medicine or Socrates in electronic guise]
    J L Wautier
    Institut National de la Transfusion Sanguine, Paris, France
    Transfus Clin Biol 12:150-2. 2005
    ..Several electronic companies have given a free access to the programmes and sites. The use of electronic media leads to an adaptation of teaching methods making them more interactive...
  19. doi [Karl Landsteiner discovers the blood groups]
    J J Lefrere
    Institut National de la Transfusion Sanguine, rue Alexandre Cabanel, Paris, France
    Transfus Clin Biol 17:1-8. 2010
    ..This paper retraces the hard career of this American scientist of Austrian origin, and describes the circumstances that led his research to the discoveries, which were turning points in the history of the immunology...
  20. doi Hepatitis G virus: a suitable marker of in vivo efficacy for pathogen inactivation
    J J Lefrere
    Department of Blood Transmissible Agents, National Institute of Blood Transfusion, Paris, France
    Vox Sang 95:76-8. 2008
    ..The in vivo efficacy of pathogen inactivation methods could be assessed by the absence of hepatitis G virus markers after transfusion of pathogen-inactivated blood products, in recipients susceptible to infection before the transfusion...
  21. doi [First French transfusions (1667-1668)]
    P Jaulin
    Institut National de la Transfusion Sanguine, 6, rue Alexandre Cabanel, 75015 Paris, France
    Transfus Clin Biol 17:205-17. 2010
    ..Following the death of a transfused patient, a death most likely related to acute intravascular hemolysis, the practice of transfusion was prohibited, on both sides of the Channel, by decision of Parliament...
  22. doi [Expected limits (and possible consequences) of pathogen inactivation technology]
    J J Lefrere
    Département d études des agents transmissibles par le sang, Institut National de la Transfusion Sanguine, Paris, France
    Transfus Clin Biol 18:468-71. 2011
    ..We can distinguish limitations due to adverse events related to the technology itself or to recipient susceptibility, the limits of effectiveness depending on the target, the technology, organizational, economic and geographical limits...