H Hocini

Summary

Country: France

Publications

  1. ncbi request reprint High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160
    H Hocini
    Unité INSERM U430 Immunopathologie Humaine, Hopital Broussais, Paris, France
    AIDS Res Hum Retroviruses 13:1179-85. 1997
  2. ncbi request reprint An ELISA method to measure total and specific human secretory IgA subclasses based on selective degradation by IgA1-protease
    H Hocini
    Unité INSERM U430, Hopital Broussais, 96 rue Didot 75674, Cedex 14, Paris, France
    J Immunol Methods 235:53-60. 2000
  3. pmc Active and selective transcytosis of cell-free human immunodeficiency virus through a tight polarized monolayer of human endometrial cells
    H Hocini
    INSERM U430, Paris, France
    J Virol 75:5370-4. 2001
  4. ncbi request reprint Secretory anti-human immunodeficiency virus (HIV) antibodies in colostrum and breast milk are not a major determinant of the protection of early postnatal transmission of HIV
    P Becquart
    Institut National de la Santé et de la Recherche Médicale U430, Hopital Broussais, Paris, France
    J Infect Dis 181:532-9. 2000
  5. ncbi request reprint Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women
    L Belec
    Unité INSERM U430, Immunopathologie Humaine, Hopital Broussais, and Université Pierre et Marie Curie Paris VI and Laboratoire de Virologie, Hopital Europeen Georges Pompidou, Paris, France
    J Infect Dis 184:1412-22. 2001
  6. pmc Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers
    H Hocini
    Unité INSERM U430, Paris, France
    Clin Diagn Lab Immunol 7:515-8. 2000
  7. ncbi request reprint Cervicovaginal synthesis of IgG antibodies to the immunodominant 175-199 domain of the surface glycoprotein gp46 of human T-cell leukemia virus type I
    L Belec
    Laboratory of Virology, Broussais Hospital, Paris, France
    J Med Virol 50:42-9. 1996
  8. ncbi request reprint Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM
    M Bomsel
    U332 INSERM ICGM, Paris, France
    Immunity 9:277-87. 1998
  9. ncbi request reprint Opposite effects of IL-10 on the ability of dendritic cells and macrophages to replicate primary CXCR4-dependent HIV-1 strains
    P Ancuta
    Unite d Immunopathologie Humaine, Institut National de la Sante et de la Recherche Medicale, Broussais Hospital, Paris, France
    J Immunol 166:4244-53. 2001
  10. ncbi request reprint Induction in mucosa of IgG and IgA antibodies against parenterally administered soluble immunogens
    N Decroix
    , Paris, France
    Scand J Immunol 53:401-9. 2001

Collaborators

Detail Information

Publications14

  1. ncbi request reprint High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160
    H Hocini
    Unité INSERM U430 Immunopathologie Humaine, Hopital Broussais, Paris, France
    AIDS Res Hum Retroviruses 13:1179-85. 1997
    ..However, specific S-IgA was more efficient than IgG. These features suggest that mucosal specific S-IgA to HIV-1 could be relevant in decreasing infectivity of HIV-1 in corporal fluids...
  2. ncbi request reprint An ELISA method to measure total and specific human secretory IgA subclasses based on selective degradation by IgA1-protease
    H Hocini
    Unité INSERM U430, Hopital Broussais, 96 rue Didot 75674, Cedex 14, Paris, France
    J Immunol Methods 235:53-60. 2000
    ..The major subclass of colostral S-IgA antibodies to gp160 was found to be of the alpha1 isotype but the specific activity of anti-HIV-gp160 S-IgA2 was, however, higher than that of S-IgA1...
  3. pmc Active and selective transcytosis of cell-free human immunodeficiency virus through a tight polarized monolayer of human endometrial cells
    H Hocini
    INSERM U430, Paris, France
    J Virol 75:5370-4. 2001
    ..These findings provide new insights into the initial events occurring during heterosexual transmission of the virus...
  4. ncbi request reprint Secretory anti-human immunodeficiency virus (HIV) antibodies in colostrum and breast milk are not a major determinant of the protection of early postnatal transmission of HIV
    P Becquart
    Institut National de la Santé et de la Recherche Médicale U430, Hopital Broussais, Paris, France
    J Infect Dis 181:532-9. 2000
    ..These results suggest that humoral mucosal immunity to HIV does not appear as a predominant factor for protection against viral transmission through breast milk...
  5. ncbi request reprint Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women
    L Belec
    Unité INSERM U430, Immunopathologie Humaine, Hopital Broussais, and Université Pierre et Marie Curie Paris VI and Laboratoire de Virologie, Hopital Europeen Georges Pompidou, Paris, France
    J Infect Dis 184:1412-22. 2001
    ....
  6. pmc Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers
    H Hocini
    Unité INSERM U430, Paris, France
    Clin Diagn Lab Immunol 7:515-8. 2000
    ..These observations indicate that the inhibitory effect of SLPI is restricted to free HIV-1 in corporal fluids...
  7. ncbi request reprint Cervicovaginal synthesis of IgG antibodies to the immunodominant 175-199 domain of the surface glycoprotein gp46 of human T-cell leukemia virus type I
    L Belec
    Laboratory of Virology, Broussais Hospital, Paris, France
    J Med Virol 50:42-9. 1996
    ..Since anti-gp46/175-Pro-199 antibodies usually support reactivities to neutralizing domains, their presence could be relevant for limiting HTLV-I transmission via cervicovaginal secretions...
  8. ncbi request reprint Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM
    M Bomsel
    U332 INSERM ICGM, Paris, France
    Immunity 9:277-87. 1998
    ..These results suggest that induction of mucosal immunity to HIV envelope proteins may impair the transcytotic route of HIV mucosal transmission...
  9. ncbi request reprint Opposite effects of IL-10 on the ability of dendritic cells and macrophages to replicate primary CXCR4-dependent HIV-1 strains
    P Ancuta
    Unite d Immunopathologie Humaine, Institut National de la Sante et de la Recherche Medicale, Broussais Hospital, Paris, France
    J Immunol 166:4244-53. 2001
    ..These findings suggest that increased levels of IL-10 observed in HIV-1-infected patients with disease progression may favor the replication of X4 HIV-1 strains in vivo...
  10. ncbi request reprint Induction in mucosa of IgG and IgA antibodies against parenterally administered soluble immunogens
    N Decroix
    , Paris, France
    Scand J Immunol 53:401-9. 2001
    ..The results indicate that mucosal immunity to peptides that are candidates for human vaccinations may be achieved by parenteral adjuvant-free immunization with peptide coupled to TT...
  11. ncbi request reprint Antibodies to C-C chemokine receptor 5 in normal human IgG block infection of macrophages and lymphocytes with primary R5-tropic strains of HIV-1
    H Bouhlal
    , , Paris, France
    J Immunol 166:7606-11. 2001
    ..Our results suggest that anti-CCR5 Abs from healthy immunocompetent donors may be suitable for development of novel passive immunotherapy regimens in specific clinical settings in HIV infection...
  12. pmc Detection of Y chromosome DNA as evidence of semen in cervicovaginal secretions of sexually active women
    N Chomont
    INSERM U430, , Paris, France
    Clin Diagn Lab Immunol 8:955-8. 2001
    ..The detection of cell-associated male DNA with a highly sensitive and specific procedure such as Y PCR constitutes a method of choice to detect semen traces in female genital secretions...
  13. ncbi request reprint [Breast lobular carcinoma in situ: diagnosis and evolution]
    M Espie
    Centre des Maladies du Sein, Hopital Saint Louis, Paris, France
    Gynecol Obstet Fertil 33:964-9. 2005
    ..The clinical and radiological diagnosis remains difficult and the choice of therapies varies according to teams, ranging from mere surveillance to mastectomy...
  14. ncbi request reprint [Invasive lobular carcinoma of the breast: specific diagnosis and evolution]
    M Espie
    Centre des Maladies du Sein, Hopital Saint Louis, 1, avenue Claude Vellefaux, 75475 Paris Cedex 10, France
    Gynecol Obstet Fertil 34:3-7. 2006
    ..The choice of therapies depends on the individual characteristics of each patient and of the biological features of each tumour. However, lobular carcinomas seem to be less responsive to chemotherapy...