Jean Louis Herrmann
Dubois V, Viljoen A, Laencina L, Le Moigne V, Bernut A, Dubar F, et al
. MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family. Proc Natl Acad Sci U S A. 2018;: pubmed publisher
Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, et al
. Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus. Proc Natl Acad Sci U S A. 2018;115:E1002-E1011 pubmed publisher
..This study attributes an unexpected and genuine biological role to the underexplored mycobacterial ESX-4 system and its substrates. ..
Le Moigne V, Belon C, Goulard C, Accard G, Bernut A, Pitard B, et al
. MgtC as a Host-Induced Factor and Vaccine Candidate against Mycobacterium abscessus Infection. Infect Immun. 2016;84:2895-903 pubmed publisher
..abscessus infection. These results emphasize the importance of M. abscessus MgtC in vivo and provide a basis for the development of novel therapeutic tools against pulmonary M. abscessus infections in CF patients. ..
Dubois V, Laencina L, Bories A, Le Moigne V, Pawlik A, Herrmann J, et al
. Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes. J Vis Exp. 2018;: pubmed publisher
..abscessus adaptation to intracellular life. Both approaches give us an insight into M. abscessus virulence factors that enable M. abscessus to colonize the airways in humans. ..
Roux A, Viljoen A, Bah A, Simeone R, Bernut A, Laencina L, et al
. The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages. Open Biol. 2016;6: pubmed
..In conclusion, M. abscessus S exhibits traits inside macrophages that are reminiscent of slow-growing mycobacterial species. ..