Zannetti C, Parroche P, Panaye M, Roblot G, Gruffat H, Manet E, et al
. TLR9 transcriptional regulation in response to double-stranded DNA viruses. J Immunol. 2014;193:3398-408 pubmed publisher
..These results provide a framework for understanding the complex pathways involved in transcriptional regulation of TLR9, immune induction, and inflammation against viruses. ..
Zannetti C, Roblot G, Charrier E, Ainouze M, Tout I, Briat F, et al
. Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens. J Immunol. 2016;197:356-67 pubmed publisher
..We think our findings could potentially aid therapeutic approaches against chronic liver diseases that activate the inflammasome. ..
Hasan U, Zannetti C, Parroche P, Goutagny N, Malfroy M, Roblot G, et al
. The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter. J Exp Med. 2013;210:1369-87 pubmed publisher
..Our studies highlight a novel HPV16-mediated mechanism that combines epigenetic and transcriptional events to suppress a key innate immune sensor...