Bruno P Guiard

Summary

Country: France

Publications

  1. ncbi 5-HT2 ligands in the treatment of anxiety and depression
    Gaël Quesseveur
    EA3544 University Paris XI, Laboratoire de Neuropharmacologie, Fac Pharmacie, F 92296, Chatenay Malabry Cedex, France
    Expert Opin Investig Drugs 21:1701-25. 2012
  2. ncbi Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration
    Quentin Rainer
    Equipe d Accueil 3544, Laboratoire de Neuropharmacologie, Universite Paris XI, Chatenay Malabry, France
    Mol Pharmacol 81:106-12. 2012
  3. ncbi Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa K1Z7K4 ON, Canada
    Curr Drug Targets 10:1069-84. 2009
  4. ncbi Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons
    Noam S Katz
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Psychopharmacol 24:1223-35. 2010
  5. ncbi Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review
    Alain M Gardier
    Fac Pharmacie, Univ Paris Sud, EA 3544, Chatenay Malabry Cedex F 92296, France
    Fundam Clin Pharmacol 23:23-42. 2009
  6. ncbi Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus
    Thierry Deltheil
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex F 92296, France
    Pharmacol Biochem Behav 90:174-83. 2008
  7. ncbi Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder
    Mostafa El Mansari
    University of Ottawa Institute of Mental Health Research, Ontario, Canada
    CNS Neurosci Ther 16:e1-17. 2010
  8. ncbi Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex
    Bruno P Guiard
    Univ Paris Sud EA 3544, Fac Pharmacie, Chatenay Malabry cedex F92296, France
    Mol Pharmacol 72:1411-8. 2007
  9. ncbi A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain
    Daniela Popa
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex, France
    Eur J Pharmacol 628:83-90. 2010
  10. ncbi Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, K1Z 7K4, Ontario, Canada
    Mol Pharmacol 74:1463-75. 2008

Collaborators

Detail Information

Publications11

  1. ncbi 5-HT2 ligands in the treatment of anxiety and depression
    Gaël Quesseveur
    EA3544 University Paris XI, Laboratoire de Neuropharmacologie, Fac Pharmacie, F 92296, Chatenay Malabry Cedex, France
    Expert Opin Investig Drugs 21:1701-25. 2012
    ..However, the potential risks related to the enhancement of monoaminergic neurotransmissions could represent a major concern...
  2. ncbi Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration
    Quentin Rainer
    Equipe d Accueil 3544, Laboratoire de Neuropharmacologie, Universite Paris XI, Chatenay Malabry, France
    Mol Pharmacol 81:106-12. 2012
    ..These results provide cellular explanations for the antidepressant effects produced by SSRIs in subjects with pathological conditions but not in naive animals or healthy volunteers...
  3. ncbi Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa K1Z7K4 ON, Canada
    Curr Drug Targets 10:1069-84. 2009
    ..This review synthetizes the pertinent litterature, focusing on the contribution of DA, to illustrate the rationale for designing improved antidepressants...
  4. ncbi Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons
    Noam S Katz
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Psychopharmacol 24:1223-35. 2010
    ..Nomifensine likely treated depression by acting on dopamine, norepinephrine and 5-HT neurons, highlighting the importance of the functional connectivity between these three monoaminergic systems...
  5. ncbi Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review
    Alain M Gardier
    Fac Pharmacie, Univ Paris Sud, EA 3544, Chatenay Malabry Cedex F 92296, France
    Fundam Clin Pharmacol 23:23-42. 2009
    ....
  6. ncbi Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus
    Thierry Deltheil
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex F 92296, France
    Pharmacol Biochem Behav 90:174-83. 2008
    ..Thus, the neurochemical sight of this question will be addressed here by examining the consequences of either a constitutive decrease or increase in brain BDNF protein levels on hippocampal extracellular levels of 5-HT in conscious mice...
  7. ncbi Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder
    Mostafa El Mansari
    University of Ottawa Institute of Mental Health Research, Ontario, Canada
    CNS Neurosci Ther 16:e1-17. 2010
    ..The elucidation of such relationships can help design new treatment strategies for MDD, especially treatment-resistant depression...
  8. ncbi Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex
    Bruno P Guiard
    Univ Paris Sud EA 3544, Fac Pharmacie, Chatenay Malabry cedex F92296, France
    Mol Pharmacol 72:1411-8. 2007
    ..A better knowledge of the complex relationship between tachykininergic, serotonergic, and glutamatergic systems within the DRN might help better understand the pathophysiology and subsequent treatment of depression...
  9. ncbi A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain
    Daniela Popa
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex, France
    Eur J Pharmacol 628:83-90. 2010
    ....
  10. ncbi Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, K1Z 7K4, Ontario, Canada
    Mol Pharmacol 74:1463-75. 2008
    ..These findings might help in designing new antidepressant strategies aimed at enhancing DA and NE neurotransmission...
  11. ncbi Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: a review
    Bruno P Guiard
    Laboratoire de Neuropharmacologie, EA 3544 MJENR, , 5, , , France
    Curr Drug Targets 7:187-201. 2006
    ..This review describes our current knowledge of the role of SP and its preferred NK1 receptors mainly in the modulation of brain serotonergic activity...