Bruno P Guiard

Summary

Country: France

Publications

  1. ncbi request reprint The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs
    Gaël Quesseveur
    Laboratory of Neuropharmacology, EA3544, University of Paris X1, 92290 Chatenay Malabry, Cedex, France
    Curr Drug Targets 14:1277-94. 2013
  2. doi request reprint 5-HT2 ligands in the treatment of anxiety and depression
    Gaël Quesseveur
    EA3544 University Paris XI, Laboratoire de Neuropharmacologie, Fac Pharmacie, F 92296, Chatenay Malabry Cedex, France
    Expert Opin Investig Drugs 21:1701-25. 2012
  3. doi request reprint Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration
    Quentin Rainer
    Equipe d Accueil 3544, Laboratoire de Neuropharmacologie, Universite Paris XI, Chatenay Malabry, France
    Mol Pharmacol 81:106-12. 2012
  4. ncbi request reprint Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa K1Z7K4 ON, Canada
    Curr Drug Targets 10:1069-84. 2009
  5. doi request reprint Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons
    Noam S Katz
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Psychopharmacol 24:1223-35. 2010
  6. doi request reprint Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review
    Alain M Gardier
    Fac Pharmacie, Univ Paris Sud, EA 3544, Chatenay Malabry Cedex F 92296, France
    Fundam Clin Pharmacol 23:23-42. 2009
  7. pmc Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder
    Mostafa El Mansari
    University of Ottawa Institute of Mental Health Research, Ontario, Canada
    CNS Neurosci Ther 16:e1-17. 2010
  8. ncbi request reprint Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus
    Thierry Deltheil
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex F 92296, France
    Pharmacol Biochem Behav 90:174-83. 2008
  9. ncbi request reprint Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex
    Bruno P Guiard
    Univ Paris Sud EA 3544, Fac Pharmacie, Chatenay Malabry cedex F92296, France
    Mol Pharmacol 72:1411-8. 2007
  10. doi request reprint A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain
    Daniela Popa
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex, France
    Eur J Pharmacol 628:83-90. 2010

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs
    Gaël Quesseveur
    Laboratory of Neuropharmacology, EA3544, University of Paris X1, 92290 Chatenay Malabry, Cedex, France
    Curr Drug Targets 14:1277-94. 2013
    ....
  2. doi request reprint 5-HT2 ligands in the treatment of anxiety and depression
    Gaël Quesseveur
    EA3544 University Paris XI, Laboratoire de Neuropharmacologie, Fac Pharmacie, F 92296, Chatenay Malabry Cedex, France
    Expert Opin Investig Drugs 21:1701-25. 2012
    ..In this context, the 5-HT(2) receptor subtypes represent promising targets but their precise roles have yet to be determined...
  3. doi request reprint Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration
    Quentin Rainer
    Equipe d Accueil 3544, Laboratoire de Neuropharmacologie, Universite Paris XI, Chatenay Malabry, France
    Mol Pharmacol 81:106-12. 2012
    ..These results provide cellular explanations for the antidepressant effects produced by SSRIs in subjects with pathological conditions but not in naive animals or healthy volunteers...
  4. ncbi request reprint Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa K1Z7K4 ON, Canada
    Curr Drug Targets 10:1069-84. 2009
    ..This review synthetizes the pertinent litterature, focusing on the contribution of DA, to illustrate the rationale for designing improved antidepressants...
  5. doi request reprint Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons
    Noam S Katz
    University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada
    J Psychopharmacol 24:1223-35. 2010
    ..Nomifensine likely treated depression by acting on dopamine, norepinephrine and 5-HT neurons, highlighting the importance of the functional connectivity between these three monoaminergic systems...
  6. doi request reprint Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review
    Alain M Gardier
    Fac Pharmacie, Univ Paris Sud, EA 3544, Chatenay Malabry Cedex F 92296, France
    Fundam Clin Pharmacol 23:23-42. 2009
    ....
  7. pmc Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder
    Mostafa El Mansari
    University of Ottawa Institute of Mental Health Research, Ontario, Canada
    CNS Neurosci Ther 16:e1-17. 2010
    ..The elucidation of such relationships can help design new treatment strategies for MDD, especially treatment-resistant depression...
  8. ncbi request reprint Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus
    Thierry Deltheil
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex F 92296, France
    Pharmacol Biochem Behav 90:174-83. 2008
    ..Thus, the neurochemical sight of this question will be addressed here by examining the consequences of either a constitutive decrease or increase in brain BDNF protein levels on hippocampal extracellular levels of 5-HT in conscious mice...
  9. ncbi request reprint Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex
    Bruno P Guiard
    Univ Paris Sud EA 3544, Fac Pharmacie, Chatenay Malabry cedex F92296, France
    Mol Pharmacol 72:1411-8. 2007
    ..A better knowledge of the complex relationship between tachykininergic, serotonergic, and glutamatergic systems within the DRN might help better understand the pathophysiology and subsequent treatment of depression...
  10. doi request reprint A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain
    Daniela Popa
    Univ Paris Sud, EA 3544, Fac Pharmacie, Chatenay Malabry Cedex, France
    Eur J Pharmacol 628:83-90. 2010
    ....
  11. doi request reprint Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus
    Bruno P Guiard
    University of Ottawa Institute of Mental Health Research, 1145 Carling Avenue, Ottawa, K1Z 7K4, Ontario, Canada
    Mol Pharmacol 74:1463-75. 2008
    ..These findings might help in designing new antidepressant strategies aimed at enhancing DA and NE neurotransmission...
  12. ncbi request reprint Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: a review
    Bruno P Guiard
    Laboratoire de Neuropharmacologie, EA 3544 MJENR, Faculte de Pharmacie, 5, rue J B Clement, 92296 Chatenay Malabry Cedex, France
    Curr Drug Targets 7:187-201. 2006
    ..This review describes our current knowledge of the role of SP and its preferred NK1 receptors mainly in the modulation of brain serotonergic activity...
  13. doi request reprint Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice
    Jean Philippe Guilloux
    Univ Paris Sud, EA3544, Faculte de Pharmacie, Chatenay Malabry F 92296, France
    Neuropharmacology 73:147-59. 2013
    ..Vortioxetine effects were observed at low levels of 5-HT transporter occupancy, suggesting an alternative mechanism of action to 5-HT reuptake inhibition...