M Guerre-Millo

Summary

Country: France

Publications

  1. ncbi Adipose tissue hormones
    M Guerre-Millo
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, Paris, France
    J Endocrinol Invest 25:855-61. 2002
  2. ncbi Extending the glucose/fatty acid cycle: a glucose/adipose tissue cycle
    M Guerre-Millo
    U 465 INSERM, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Biochem Soc Trans 31:1161-4. 2003
  3. ncbi Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity
    Corneliu Henegar
    INSERM, UMR S 872, Les Cordeliers, Eq, 7 Nutriomique and Eq, 13, Paris, F 75006 France
    Genome Biol 9:R14. 2008
  4. ncbi Adiponectin: an update
    M Guerre-Millo
    Service de Nutrition, Inserm U872, Hopital Hotel Dieu, 1, place du parvis de Notre Dame, 75181 Paris Cedex 04, France
    Diabetes Metab 34:12-8. 2008
  5. ncbi [Adipose tissue secretory function: implication in metabolic and cardiovascular complications of obesity]
    Michele Guerre-Millo
    INSERM, U755 Nutriomique, 75004 Paris, France
    J Soc Biol 200:37-43. 2006
  6. ncbi Adipose tissue and adipokines: for better or worse
    M Guerre-Millo
    U 465 INSERM, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, 15, rue de l Ecole de Medecine, 75006 Paris, France
    Diabetes Metab 30:13-9. 2004
  7. ncbi Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans
    V Poitout
    INSERM U341, Service de Diabetologie, Paris, France
    Endocrinology 139:822-6. 1998
  8. ncbi Transcriptional effect of hypoxia on placental leptin
    A Grosfeld
    INSERM U 465, Paris, France
    FEBS Lett 502:122-6. 2001
  9. ncbi Regulation of glucose transport and transporter 4 (GLUT-4) in muscle and adipocytes of sucrose-fed rats: effects of N-3 poly- and monounsaturated fatty acids
    E Peyron-Caso
    Department of Diabetes INSERM U341, Hotel Dieu Hospital, Paris, France
    Horm Metab Res 34:360-6. 2002
  10. ncbi Adipose tissue inflammation and liver pathology in human obesity
    J Tordjman
    INSERM, U872, 15, rue de l Ecole de Medecine, 75007 Paris, F 75006 France
    Diabetes Metab 34:658-63. 2008

Collaborators

Detail Information

Publications24

  1. ncbi Adipose tissue hormones
    M Guerre-Millo
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, Paris, France
    J Endocrinol Invest 25:855-61. 2002
    ..The rationale for therapeutic strategies aimed at compensating adverse effects resulting from overproduction or lack of a specific adipose secretory product will be discussed...
  2. ncbi Extending the glucose/fatty acid cycle: a glucose/adipose tissue cycle
    M Guerre-Millo
    U 465 INSERM, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Biochem Soc Trans 31:1161-4. 2003
    ....
  3. ncbi Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity
    Corneliu Henegar
    INSERM, UMR S 872, Les Cordeliers, Eq, 7 Nutriomique and Eq, 13, Paris, F 75006 France
    Genome Biol 9:R14. 2008
    ..However, the overall importance of these alterations, and their long-term impact on the metabolic functions of the WAT and on its morphology, remain unclear...
  4. ncbi Adiponectin: an update
    M Guerre-Millo
    Service de Nutrition, Inserm U872, Hopital Hotel Dieu, 1, place du parvis de Notre Dame, 75181 Paris Cedex 04, France
    Diabetes Metab 34:12-8. 2008
    ..Finally, AdipoR activation to mimic adiponectin actions could prove beneficial to reduce metabolic risk factors in conditions, such as obesity, where low adiponectinemia prevails...
  5. ncbi [Adipose tissue secretory function: implication in metabolic and cardiovascular complications of obesity]
    Michele Guerre-Millo
    INSERM, U755 Nutriomique, 75004 Paris, France
    J Soc Biol 200:37-43. 2006
    ..The local and systemic consequences of interactions between macrophages and adipocytes are currently actively studied, to understand their potential implication in the metabolic and cardiovascular complications associated with obesity...
  6. ncbi Adipose tissue and adipokines: for better or worse
    M Guerre-Millo
    U 465 INSERM, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, 15, rue de l Ecole de Medecine, 75006 Paris, France
    Diabetes Metab 30:13-9. 2004
    ....
  7. ncbi Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans
    V Poitout
    INSERM U341, Service de Diabetologie, Paris, France
    Endocrinology 139:822-6. 1998
    ..These results suggest that, in normal rodent islets, leptin specifically inhibits IBMX-potentiated glucose-induced insulin secretion, through a direct effect involving at least one of the three isoforms of OB-R expressed in islets...
  8. ncbi Transcriptional effect of hypoxia on placental leptin
    A Grosfeld
    INSERM U 465, Paris, France
    FEBS Lett 502:122-6. 2001
    ..These data indicate that leptin is up-regulated by hypoxia through a transcriptional mechanism likely to involve distinct hypoxia-responsive cis-acting sequences on the promoter...
  9. ncbi Regulation of glucose transport and transporter 4 (GLUT-4) in muscle and adipocytes of sucrose-fed rats: effects of N-3 poly- and monounsaturated fatty acids
    E Peyron-Caso
    Department of Diabetes INSERM U341, Hotel Dieu Hospital, Paris, France
    Horm Metab Res 34:360-6. 2002
    ..Dietary regulation of Glut-4 proteins appears to be tissue specific and might depend on insulin stimulation and/or duration of dietary interventions...
  10. ncbi Adipose tissue inflammation and liver pathology in human obesity
    J Tordjman
    INSERM, U872, 15, rue de l Ecole de Medecine, 75007 Paris, F 75006 France
    Diabetes Metab 34:658-63. 2008
    ..The aim of this review is to present the most upto-date knowledge regarding the relationships between inflammatory processes in WAT and non-alcoholic liver disease in human obesity...
  11. ncbi PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance
    M Guerre-Millo
    Unit 465, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    Diabetes 50:2809-14. 2001
    ..These data suggest that PPAR-alpha plays a role for the development of IR in response to a Western-type high-fat diet...
  12. ncbi Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen
    S Turban
    U 465 INSERM, , 75006 Paris, France
    J Cell Biochem 82:666-73. 2001
    ..These characteristics might account for the differential response of these adipose proteins to variations in the systemic environment...
  13. ncbi Relevance of increased serum cystatin C to vascular alterations in obese children
    B Dubern
    Institute of Cardiometabolism and Nutrition, Paris, France INSERM, Paris, France
    Pediatr Obes 7:374-81. 2012
    ..Epidemiological studies report a positive relationship between serum cystatin C and cardiovascular outcomes in adults. Here, we tested the relevance of cystatin C as a biomarker for early vascular alterations in severely obese children...
  14. ncbi Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation
    I Sahly
    CERTO, Faculte Necker, 156 rue de Vaugirard, 75015 Paris, France and INSERM U465, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Hum Mol Genet 7:1437-47. 1998
    ....
  15. ncbi Specific increase in leptin production in obese (falfa) rat adipose cells
    Sophie Turban
    U 465 INSERM, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Biochem J 362:113-8. 2002
    ..Increased leptin production might be related to disruption of leptin signalling by the fa mutation...
  16. ncbi Promoter adiponectin polymorphisms and waist/hip ratio variation in a prospective French adults study
    G Dolley
    INSERM, U872, Nutriomique team 7, Cordelier Research Center, Paris, France
    Int J Obes (Lond) 32:669-75. 2008
    ..Some of these adiponectin polymorphisms have been associated with BMI in cross-sectional studies...
  17. ncbi Hypoxia increases leptin expression in human PAZ6 adipose cells
    A Grosfeld
    INSERM U 465, Paris, France
    Diabetologia 45:527-30. 2002
    ..CONCLUSION/INTERPRETATION: Hypoxia markedly and specifically increased leptin gene expression through activation of the leptin gene promoter, and this resulted in an increased leptin production by human PAZ6 adipocytes...
  18. ncbi Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose
    Marc Gilbert
    CNRS UMR 7059, Universite Pierre et Marie Curie, Paris, France
    Diabetes 52:277-82. 2003
    ..This process could contribute to the limiting of hyperphagia, primarily when leptin signaling is altered, as in the obese state...
  19. ncbi Potential contribution of adipose tissue to elevated serum cystatin C in human obesity
    Nadia Naour
    INSERM, U872, Paris, France
    Obesity (Silver Spring) 17:2121-6. 2009
    ....
  20. ncbi Leptin: a potential marker of placental insufficiency
    Jacques Lepercq
    Service de Gynecologie Obstetrique, Hopital Cochin Saint Vincent de Paul, Paris, France
    Gynecol Obstet Invest 55:151-5. 2003
    ..60). These data demonstrate that placental insufficiency is associated with a dramatic increase in placental leptin production. This results in a rise in maternal leptinemia that may be taken as an early index of placental dysfunction...
  21. ncbi Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance
    Laurent Yvan-Charvet
    Unit 465, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    Diabetes 54:991-9. 2005
    ..These data support the idea that AT2R-dependent Ang II signaling increases adipose cell mass and glucose intolerance and thus could participate to the deleterious effects of a high-fat diet...
  22. ncbi Hypoxia-inducible factor 1 transactivates the human leptin gene promoter
    Alexandra Grosfeld
    INSERM U 465, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, 15 rue de l Ecole de Medecine, 75006 Paris, France
    J Biol Chem 277:42953-7. 2002
    ..These data demonstrate that leptin is a new hypoxia-inducible gene, which is stimulated in a placental cell line through HIF-1 interaction with a consensus HRE site located at -116 in the proximal promoter...
  23. ncbi Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status
    Joan Tordjman
    INSERM, U872, Eq7, 15 Rue de l Ecole de Medicine, 75007 Paris, France
    J Hepatol 51:354-62. 2009
    ..Here, we evaluated the influence of glycemic status and extended the analysis to the spectrum of obesity-linked liver damage...
  24. ncbi Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women
    Soraya Taleb
    Institut National de la Santé et de la Recherche Médicale U755, Nutrition Department, Hotel Dieu, Place du Parvis Notre Dame, 75004 Paris, France
    J Clin Endocrinol Metab 91:1042-7. 2006
    ..Obesity is characterized by high levels of CTSS in the circulation and in sc white adipose tissue (scWAT)...