Jean Pierre Grunfeld

Summary

Country: France

Publications

  1. doi request reprint Lithium nephrotoxicity revisited
    Jean Pierre Grunfeld
    Department of Nephrology, Necker Hospital, Universite Paris Descartes, Paris, France
    Nat Rev Nephrol 5:270-6. 2009
  2. ncbi request reprint [Alport's syndrome: apropos of 2 families]
    J P Grunfeld
    Service de Nephrologie, Hopital Necker, Paris
    Nephrologie 21:295-8. 2000
  3. ncbi request reprint Ethics in renal genetics
    J P Grunfeld
    Service de Nephrologie, Hôpital Necker 149, rue de Sevres, AP HP Université Paris V René Descartes, 75743 Paris
    Nefrologia 23:11-3. 2003
  4. ncbi request reprint Congenital/inherited kidney diseases: how to identify them early and how to manage them
    Jean Pierre Grunfeld
    Hopital Necker, Universite Paris V, René Descartes, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Clin Exp Nephrol 9:192-4. 2005
  5. ncbi request reprint [Chronic glomerular diseases: understanding, detecting, treating]
    Jean Pierre Grunfeld
    Service de Nephrologie, hôpital Necker et université Paris V, 75743 Paris Cedex 15
    Rev Prat 53:1991-2. 2003
  6. ncbi request reprint [Kidney involvement in Fabry disease: results of enzyme replacement therapy.]
    Jean Pierre Grunfeld
    Universite Paris Descartes, INSERM U 507, AP HP, Hopital Necker Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Med Sci (Paris) 21:23-5. 2005
  7. ncbi request reprint Anderson-Fabry disease: its place among other genetic causes of renal disease
    Jean Pierre Grunfeld
    Service of Nephrology, Hopital Necker, INSERM U507, 147 Rue de Sevres, 75743 Paris Cedex 15, France
    J Am Soc Nephrol 13:S126-9. 2002
  8. ncbi request reprint Renal disease in Fabry patients
    J P Grunfeld
    Service de Nephrologie, Hopital Necker, Paris, France
    J Inherit Metab Dis 24:71-4; discussion 65. 2001
  9. ncbi request reprint The expanding spectrum of renal diseases associated with antiphospholipid syndrome
    Fadi Fakhouri
    Department of Nephrology, AP HP, Hopital Necker, Paris, France
    Am J Kidney Dis 41:1205-11. 2003
  10. doi request reprint Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
    Aude Servais
    Department of Nephrology, Hôpital Necker Enfants Malades AP HP, Paris, France
    Kidney Int 82:454-64. 2012

Detail Information

Publications47

  1. doi request reprint Lithium nephrotoxicity revisited
    Jean Pierre Grunfeld
    Department of Nephrology, Necker Hospital, Universite Paris Descartes, Paris, France
    Nat Rev Nephrol 5:270-6. 2009
    ..Experimental and clinical evidence demonstrates the efficacy of the ENaC inhibitor amiloride for the treatment of lithium-induced NDI; however, whether this agent can prevent the long-term adverse effects of lithium is not yet known...
  2. ncbi request reprint [Alport's syndrome: apropos of 2 families]
    J P Grunfeld
    Service de Nephrologie, Hopital Necker, Paris
    Nephrologie 21:295-8. 2000
    ..The consequences of these data on diagnosis and genetic counseling are discussed...
  3. ncbi request reprint Ethics in renal genetics
    J P Grunfeld
    Service de Nephrologie, Hôpital Necker 149, rue de Sevres, AP HP Université Paris V René Descartes, 75743 Paris
    Nefrologia 23:11-3. 2003
  4. ncbi request reprint Congenital/inherited kidney diseases: how to identify them early and how to manage them
    Jean Pierre Grunfeld
    Hopital Necker, Universite Paris V, René Descartes, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Clin Exp Nephrol 9:192-4. 2005
  5. ncbi request reprint [Chronic glomerular diseases: understanding, detecting, treating]
    Jean Pierre Grunfeld
    Service de Nephrologie, hôpital Necker et université Paris V, 75743 Paris Cedex 15
    Rev Prat 53:1991-2. 2003
  6. ncbi request reprint [Kidney involvement in Fabry disease: results of enzyme replacement therapy.]
    Jean Pierre Grunfeld
    Universite Paris Descartes, INSERM U 507, AP HP, Hopital Necker Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Med Sci (Paris) 21:23-5. 2005
    ..However, when enzyme therapy is initiated too late, when renal scars are already present, it should be associated with additional therapy as in other glomerular diseases. double dagger...
  7. ncbi request reprint Anderson-Fabry disease: its place among other genetic causes of renal disease
    Jean Pierre Grunfeld
    Service of Nephrology, Hopital Necker, INSERM U507, 147 Rue de Sevres, 75743 Paris Cedex 15, France
    J Am Soc Nephrol 13:S126-9. 2002
  8. ncbi request reprint Renal disease in Fabry patients
    J P Grunfeld
    Service de Nephrologie, Hopital Necker, Paris, France
    J Inherit Metab Dis 24:71-4; discussion 65. 2001
    ..Significant renal disease is much less common in women carriers of the disease. However, renal changes do occur, which may progress to ESRF as in male patients...
  9. ncbi request reprint The expanding spectrum of renal diseases associated with antiphospholipid syndrome
    Fadi Fakhouri
    Department of Nephrology, AP HP, Hopital Necker, Paris, France
    Am J Kidney Dis 41:1205-11. 2003
    ..We report 9 cases of glomerulonephritis associated with APS. These cases are characterized by predominant pathological features distinct from vascular APS nephropathy...
  10. doi request reprint Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies
    Aude Servais
    Department of Nephrology, Hôpital Necker Enfants Malades AP HP, Paris, France
    Kidney Int 82:454-64. 2012
    ..The localization of the C3 deposits may be under the influence of MCP expression...
  11. ncbi request reprint SLE and idiopathic nephrotic syndrome: coincidence or not?
    Alexandre Hertig
    Department of Nephrology, Necker Hospital, Paris, France
    Am J Kidney Dis 40:1179-84. 2002
    ..The association of systemic lupus erythematosus (SLE) with minimal change disease (MCD) and/or focal and segmental glomerulosclerosis (FSGS) has been described in isolated case reports. The relevance of this association is still debated...
  12. pmc Late-onset nephropathic cystinosis: clinical presentation, outcome, and genotyping
    Aude Servais
    Department of Nephrology, Necker Hospital, 149 rue de Sevres, 75015 Paris, France
    Clin J Am Soc Nephrol 3:27-35. 2008
    ....
  13. ncbi request reprint Mesangial IgG glomerulonephritis: a distinct type of primary glomerulonephritis
    Fadi Fakhouri
    Department of Nephrology, INSERM Unit 345, Hopital Necker, Paris, France
    J Am Soc Nephrol 13:379-87. 2002
    ..Mesangial IgG glomerulonephritis is a distinct, albeit rare, type of glomerulonephritis that exhibits far from benign outcome and may recur in renal transplants...
  14. ncbi request reprint Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis
    Marie Lino
    Service d Hépatologie AP HP, Hopital Necker, Paris, France
    Am J Kidney Dis 46:e41-6. 2005
    ..Tubulointerstitial nephritis and Fanconi syndrome have to be added to the spectrum of renal diseases associated with primary biliary cirrhosis...
  15. ncbi request reprint Lithium-induced nephropathy: Rate of progression and prognostic factors
    Claire Presne
    AP HP, Hopital Necker, Service de Néphrologie et Université Paris V, Paris, France
    Kidney Int 64:585-92. 2003
    ..The aim of this study is to document the rate of progression of lithium-induced nephropathy and its prognostic factors, and to provide an estimation of the percentage of lithium-induced ESRD in France...
  16. doi request reprint Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome
    Fadi Fakhouri
    Department of Nephrology, Assistance Publique Hopitaux de Paris, Hopital Necker, Universite Paris Descartes, INSERM U845, Paris, France
    Blood 112:4542-5. 2008
    ..Our results suggest that an abnormal control of the complement alternative pathway is a risk factor for the occurrence of HELLP syndrome...
  17. ncbi request reprint Steroid-sensitive nephrotic syndrome: from childhood to adulthood
    Fadi Fakhouri
    Department of Nephrology, Assistance Publique Hopitaux de Paris, Hopital Necker Enfants Malades, Paris, France
    Am J Kidney Dis 41:550-7. 2003
    ..We undertook to conduct a retrospective study of the outcome in adulthood of a large cohort of patients diagnosed with an SSNS during childhood...
  18. pmc Urinary procollagen III aminoterminal propeptide (PIIINP): a fibrotest for the nephrologist
    Balsam El Ghoul
    Department of Nephrology, Universite Paris Descartes, Hopital Necker, Paris, France
    Clin J Am Soc Nephrol 5:205-10. 2010
    ..Thus, a noninvasive alternative to KB is required. Collagen type III amino-terminal propeptide (PIIINP) is a degradation product of collagen type III, the increase of which may reflect an ongoing fibrotic process...
  19. pmc Renal involvement in cystic fibrosis: diseases spectrum and clinical relevance
    Yasmina Yahiaoui
    Department of Nephrology, Hôpital du Kremlin Bicêtre, 78 rue du Général Leclerc 94275 Le Kremlin Bicêtre, France
    Clin J Am Soc Nephrol 4:921-8. 2009
    ..Clinically relevant kidney involvement is uncommonly described in adult patients with cystic fibrosis (CF). We sought to report on a series of patients with CF and kidney biopsy-documented renal involvement...
  20. ncbi request reprint Cyclosporin therapy in patients with Alport syndrome
    Marina Charbit
    Service de Nephrologie Pediatrique, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743, Paris Cedex 15, France
    Pediatr Nephrol 22:57-63. 2007
    ..Based on these results we conclude that while cyclosporin therapy can decrease proteinuria in most patients with AS, it may be associated with nephrotoxicity, thereby precluding its long-term use...
  21. doi request reprint Nonprogressive kidney dysfunction and outcomes in older adults with chronic kidney disease
    Balsam El-Ghoul
    Department of Nephrology, Necker Enfants Malades Hospital, Assistance Publique, Hopitaux de Paris, Paris, France
    J Am Geriatr Soc 57:2217-23. 2009
    ..To determine whether a subgroup of patients with severe but nonprogressive renal dysfunction exist and to characterize this subgroup...
  22. ncbi request reprint Recovery of acute renal failure and nephrotic syndrome following autologous stem cell transplantation for primary (AL) amyloidosis
    Renaud Snanoudj
    Nephrology Department, Hopital Necker, Assistance Publique Hopitaux de Paris, France
    Nephrol Dial Transplant 18:2175-7. 2003
  23. ncbi request reprint [Continued late referral of patients with chronic kidney disease. Causes, consequences, and approaches to improvement]
    Paul Jungers
    Service de Nephrologie, INSERM U507, Universite Paris Descartes, Faculte de Medecine, AP HP, Hopital Necker Enfants Malades, Paris
    Presse Med 35:17-22. 2006
    ..We sought to determine whether these efforts have led to improved predialysis care of these patients...
  24. ncbi request reprint The spectrum of systemic involvement in adults presenting with renal lesion and mitochondrial tRNA(Leu) gene mutation
    Bruno Guery
    Service de Néphrologie and INSERM U507, Hopital Necker, Paris
    J Am Soc Nephrol 14:2099-108. 2003
    ..Renal transplantation may be offered to these patients, despite a high incidence of steroid-induced diabetes mellitus...
  25. ncbi request reprint Antiphospholipid syndrome nephropathy
    Dominique Nochy
    Service of Pathology, Georges Pompidou European Hospital, Paris, France
    J Nephrol 15:446-61. 2002
  26. ncbi request reprint Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes
    Christelle Arrondel
    INSERM U 423, Universite Rene Descartes, Hopital Necker Enfants Malades, Paris, France
    J Am Soc Nephrol 13:65-74. 2002
    ..The two others (R1165L and S96L) are new mutations, although one of them affects a codon (R1165), found elsewhere to be mutated in Sebastian syndrome...
  27. doi request reprint Progress in nephron sparing therapy for renal cell carcinoma and von Hippel-Lindau disease
    Dominique Joly
    Faculte de Medicine, Universite Paris Descartes, Paris, France
    J Urol 185:2056-60. 2011
    ..We evaluated renal cell carcinoma treatments in the long term in a large series of patients with von Hippel-Lindau disease...
  28. doi request reprint [Renal biopsies in Fabry disease: a multicenter French study]
    Laure Helene Noel
    Service d Anatomopathologie, Inserm U1016, Hopital Necker, Université Descartes, Sorbonne Cité, AP HP, 75015 Paris, France
    Nephrol Ther 8:433-8. 2012
    ..The extend of fibrous changes was not tightly correlated with age of the patients. The results of this study suggest that renal biopsy is of value before initiating enzyme replacement therapy, in patients older than 30 to 40 years...
  29. ncbi request reprint Renal involvement in monoclonal (type I) cryoglobulinemia: two cases associated with IgG3 kappa cryoglobulin
    Alexandre Karras
    Service de Nephrologie, Laboratoire d Immunologie, INSERM U507, Hopital Necker, Paris, France
    Am J Kidney Dis 40:1091-6. 2002
    ..Although 18 cases of type I cryoglobulinemia with biopsy-proven glomerulonephritis have been reported to date, this is the first characterization of immunoglobulin heavy-chain isotype in this disease...
  30. ncbi request reprint Octogenarians reaching end-stage renal disease: cohort study of decision-making and clinical outcomes
    Dominique Joly
    Nephrology Unit, Necker Hospital and Université René Descartes Paris V, Paris, France
    J Am Soc Nephrol 14:1012-21. 2003
    ....
  31. ncbi request reprint Renal and thymic pathology in thymoma-associated nephropathy: report of 21 cases and review of the literature
    Alexandre Karras
    Service de Nephrologie, Hopital Necker, Paris, France
    Nephrol Dial Transplant 20:1075-82. 2005
    ..Renal disease has rarely been observed in association with thymoma...
  32. ncbi request reprint Cystic kidney disease, chromophobe renal cell carcinoma and TCF2 (HNF1 beta) mutations
    Gaetan Lebrun
    Universite Paris Descartes, Faculte de Medecine, AP HP, Hopital Necker Enfants Malades, Paris, France
    Nat Clin Pract Nephrol 1:115-9. 2005
    ..One of the proband's two sons had hyperechogenic kidneys and the other had renal cortical microcysts. Her 71-year-old mother had mild renal failure and small renal cysts...
  33. pmc Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome
    Aude Servais
    Department of Nephrology, Necker Hospital, Paris, France
    J Med Genet 44:193-9. 2007
    ..In some instances, HUS may be associated with an unusual glomerulonephritis with isolated C3 deposits (glomerulonephritis C3). We determined whether HUS and glomerulonephritis C3 share common genetic susceptibility factors...
  34. ncbi request reprint Enzyme replacement therapy in Anderson-Fabry's disease: beneficial clinical effect on vital organ function
    Gert De Schoenmakere
    Service de Nephrologie, Hopital Necker, Paris, France
    Nephrol Dial Transplant 18:33-5. 2003
    ..To our knowledge this is the first observation of clinical efficacy of the enzyme replacement therapy in Anderson-Fabry's disease in patients with moderately impaired renal function...
  35. ncbi request reprint Diagnosis of pheochromocytoma and laparoscopic adrenalectomy in two anephric patients with von Hippel-Lindau disease
    Dominique Chauveau
    Service de Néphrologie and INSERM U 507, Hopital Necker, Paris, France
    Am J Kidney Dis 39:E6. 2002
    ..Computed tomography scan allows early recognition, and patients on hemodialysis are responsive to laparoscopic adrenalectomy...
  36. ncbi request reprint Genotype-phenotype correlation in von Hippel-Lindau families with renal lesions
    Catherine Gallou
    INSERM U 383, Hopital Necker Enfants Malades, Paris, France
    Hum Mutat 24:215-24. 2004
    ..Overall, our data argued for a substantial contribution of the genetic change in the VHL gene to susceptibility to renal phenotype in VHL patients...
  37. doi request reprint Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant
    Eduardo Machuca
    INSERM, U574, Hopital Necker, Paris, France
    Kidney Int 75:727-35. 2009
    ..Screening for the p.R229Q variant is recommended in these patients along with further NPHS2 mutation analysis in those carrying the variant...
  38. ncbi request reprint Crystals from fat. Acute oxalate nephropathy
    Fadi Fakhouri
    Department of Nephrology, Hopital Necker, Paris, France
    Nephrol Dial Transplant 17:1348-50. 2002
  39. ncbi request reprint Monogenic renal diseases: a clinical introduction
    Jean Pierre Grunfeld
    université Paris V René Descartes, Service de Nephrologie, Hopital Necker, Paris, France
    J Nephrol 15:S43-6. 2002
    ..The post-gene era has begun and the field of research in monogenic disorders is wide open...
  40. ncbi request reprint Alagille syndrome in adult patients: it is never too late
    Antoine Jacquet
    Department of Nephrology, AP HP, Universite Paris V, Hopital Necker, Paris
    Am J Kidney Dis 49:705-9. 2007
    ..We report 2 patients in whom AGS was diagnosed in adulthood during the workup of renal disease in the absence of a well-defined familial history. Renal disease caused by AGS probably is underdiagnosed in adult patients...
  41. ncbi request reprint End-stage renal failure in Lowe syndrome
    Leila Tricot
    Service de Nephrologie, Hopital Necker, Paris, Service de Nephrologie, AURA, Paris, France
    Nephrol Dial Transplant 18:1923-5. 2003
  42. pmc Cyst infections in patients with autosomal dominant polycystic kidney disease
    Marion Sallée
    Department of Nephrology, Hopital Necker, Paris, France
    Clin J Am Soc Nephrol 4:1183-9. 2009
    ....
  43. pmc Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis
    Olivia Boyer
    INSERM U983, Tour Lavoisier, 6 étage, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    J Am Soc Nephrol 22:239-45. 2011
    ....
  44. ncbi request reprint Monitoring of glomerular filtration rate in lithium-treated outpatients--an ambulatory laboratory database surveillance
    Nader Bassilios
    Réseau Néphropar and Nephrology Department, AP HP, Necker Hospital, Paris, France
    Nephrol Dial Transplant 23:562-5. 2008
    ..The long-term risk of chronic kidney disease (CKD) in lithium (Li)-treated patients has been well established in the recent years...
  45. ncbi request reprint [Is chronic renal failure in aged patients avoidable?]
    Jean Pierre Grunfeld
    Universite Paris Descartes, Hopital Necker, 75743 Paris Cedex
    Rev Prat 55:2221-2. 2005
  46. ncbi request reprint Predictors of cardiovascular events in patients with end-stage renal disease: an analysis from the Fosinopril in dialysis study
    Michele Kessler
    Department of Nephrology, University Hospital of Nancy, Nancy, France
    Nephrol Dial Transplant 22:3573-9. 2007
    ..A risk prediction model was created from the FOSIDIAL trial to identify factors predictive of CVE and to evaluate the relative strength of known predictors when considered together in a multivariate model...
  47. ncbi request reprint Efficiency of curative and prophylactic treatment with rituximab in ADAMTS13-deficient thrombotic thrombocytopenic purpura: a study of 11 cases
    Fadi Fakhouri
    Service de Nephrologie, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Blood 106:1932-7. 2005
    ..Tolerance of rituximab was good. Rituximab is a promising first-line immunosuppressive treatment in patients with acute refractory and severe relapsing TTP related to anti-ADAMTS13 antibodies...