Sophie Grabar

Summary

Country: France

Publications

  1. ncbi request reprint HIV infection in older patients in the HAART era
    Sophie Grabar
    Service de Biostatistique et Informatique Médicale, Universite Paris Descartes, Faculte de Medecine, Hopital Cochin, Paris, France
    J Antimicrob Chemother 57:4-7. 2006
  2. ncbi request reprint Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV
    Sophie Grabar
    Department of Biostatistics, Cochin Hospital, University Paris V, Paris, France
    AIDS 18:2029-38. 2004
  3. ncbi request reprint Response to highly active antiretroviral therapy at 6 months and long-term disease progression in HIV-1 infection
    Sophie Grabar
    INSERM U720, Faculté de Médecine Pitié Salpêtrière, Universite Paris VI, and Service de Biostatistique et Informatique Médicale, Hopital Cochin, Universite Paris V, Paris, France
    J Acquir Immune Defic Syndr 39:284-92. 2005
  4. doi request reprint Maintaining antiretroviral therapy reduces the risk of AIDS-defining events in patients with uncontrolled viral replication and profound immunodeficiency
    Isabelle Kousignian
    INSERM U720, 56 Blvd Vincent Auriol, BP 335, 75625 Paris Cedex 13, France
    Clin Infect Dis 46:296-304. 2008
  5. pmc Risk of Kaposi sarcoma during the first months on combination antiretroviral therapy
    Jean Marc Lacombe
    Univ Paris 06 UMR S 943, INSERM Transfert, Paris, France
    AIDS 27:635-43. 2013
  6. doi request reprint TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
    Olivier Kosmider
    Assistance Publique Hopitaux de Paris AP HP, Service d Hematologie Biologique, Hôpital Cochin Hôtel Dieu, Paris, France
    Blood 114:3285-91. 2009
  7. ncbi request reprint Time to AIDS from 1992 to 1999 in HIV-1-infected subjects with known date of infection
    Jean Michel Tassie
    Institut National de la Santé et de la Recherche Médicale SC4, Faculte de Medecine, St Antoine Université Pierre et Marie Curie, Paris, France Epicentre, Paris, France
    J Acquir Immune Defic Syndr 30:81-7. 2002
  8. ncbi request reprint Differential impact of combination antiretroviral therapy in preventing Kaposi's sarcoma with and without visceral involvement
    Sophie Grabar
    Service de Biostatistique et Informatique Médicale, Hopital Cochin, Paris, France
    J Clin Oncol 24:3408-14. 2006
  9. doi request reprint Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy
    Christophe Piketty
    AP HP, Department of Clinical Immunology, Georges Pompidou European Hospital, Rene Descartes University, Paris, France
    AIDS 22:1203-11. 2008
  10. ncbi request reprint Effect of early syphilis infection on plasma viral load and CD4 cell count in human immunodeficiency virus-infected men: results from the FHDH-ANRS CO4 cohort
    Witold Jarzebowski
    Assistance Publique Hopitaux de Paris, Groupe Hospitalier Cochin Broca Hôtel Dieu, Unité de Biostatistique et Epidémiologie, Paris, France
    Arch Intern Med 172:1237-43. 2012

Detail Information

Publications28

  1. ncbi request reprint HIV infection in older patients in the HAART era
    Sophie Grabar
    Service de Biostatistique et Informatique Médicale, Universite Paris Descartes, Faculte de Medecine, Hopital Cochin, Paris, France
    J Antimicrob Chemother 57:4-7. 2006
    ..Information campaigns targeting older patients and their doctors are also needed to ensure timely diagnosis of HIV infection and antiretroviral treatment initiation...
  2. ncbi request reprint Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV
    Sophie Grabar
    Department of Biostatistics, Cochin Hospital, University Paris V, Paris, France
    AIDS 18:2029-38. 2004
    ..To study immunologic and clinical responses to HAART in patients over 50 years old...
  3. ncbi request reprint Response to highly active antiretroviral therapy at 6 months and long-term disease progression in HIV-1 infection
    Sophie Grabar
    INSERM U720, Faculté de Médecine Pitié Salpêtrière, Universite Paris VI, and Service de Biostatistique et Informatique Médicale, Hopital Cochin, Universite Paris V, Paris, France
    J Acquir Immune Defic Syndr 39:284-92. 2005
    ..To compare the long-term prognostic significance of different definitions of immunologic and virologic responses to highly active antiretroviral therapy (HAART) at 6 months...
  4. doi request reprint Maintaining antiretroviral therapy reduces the risk of AIDS-defining events in patients with uncontrolled viral replication and profound immunodeficiency
    Isabelle Kousignian
    INSERM U720, 56 Blvd Vincent Auriol, BP 335, 75625 Paris Cedex 13, France
    Clin Infect Dis 46:296-304. 2008
    ..The benefits of continuing antiretroviral therapy are questionable in human immunodeficiency virus (HIV) type 1-infected patients with profound immunodeficiency and multiple treatment failure due to viral resistance...
  5. pmc Risk of Kaposi sarcoma during the first months on combination antiretroviral therapy
    Jean Marc Lacombe
    Univ Paris 06 UMR S 943, INSERM Transfert, Paris, France
    AIDS 27:635-43. 2013
    ..To determine whether incident AIDS-defining Kaposi sarcoma or Pneumocystis jiroveci pneumonia (PJP) is associated with combination antiretroviral therapy (cART) initiation...
  6. doi request reprint TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
    Olivier Kosmider
    Assistance Publique Hopitaux de Paris AP HP, Service d Hematologie Biologique, Hôpital Cochin Hôtel Dieu, Paris, France
    Blood 114:3285-91. 2009
    ..3; P = .005). These results indicate that TET2 mutations observed in approximately 20% of patients, irrespective of the World Health Organization or French-American-British subtype, represent a molecular marker for good prognosis in MDS...
  7. ncbi request reprint Time to AIDS from 1992 to 1999 in HIV-1-infected subjects with known date of infection
    Jean Michel Tassie
    Institut National de la Santé et de la Recherche Médicale SC4, Faculte de Medecine, St Antoine Université Pierre et Marie Curie, Paris, France Epicentre, Paris, France
    J Acquir Immune Defic Syndr 30:81-7. 2002
    ..5, 11.2), and 20.0 years in period 3 (CI: 17.1-23.3). This lengthening in time to AIDS from 1992 to 1999 was particularly marked in the period after the introduction of triple therapy, including protease inhibitors...
  8. ncbi request reprint Differential impact of combination antiretroviral therapy in preventing Kaposi's sarcoma with and without visceral involvement
    Sophie Grabar
    Service de Biostatistique et Informatique Médicale, Hopital Cochin, Paris, France
    J Clin Oncol 24:3408-14. 2006
    ..To study the impact of different potent combined antiretroviral treatment (cART) on the incidence of HIV-associated Kaposi's sarcoma (KS) with and without visceral involvement...
  9. doi request reprint Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy
    Christophe Piketty
    AP HP, Department of Clinical Immunology, Georges Pompidou European Hospital, Rene Descartes University, Paris, France
    AIDS 22:1203-11. 2008
    ..To describe the cases of anal cancer that appeared in the French Hospital Database on HIV between 1992 and 2004 and to study risk factors of anal cancer...
  10. ncbi request reprint Effect of early syphilis infection on plasma viral load and CD4 cell count in human immunodeficiency virus-infected men: results from the FHDH-ANRS CO4 cohort
    Witold Jarzebowski
    Assistance Publique Hopitaux de Paris, Groupe Hospitalier Cochin Broca Hôtel Dieu, Unité de Biostatistique et Epidémiologie, Paris, France
    Arch Intern Med 172:1237-43. 2012
    ..Concomitant syphilis and human immunodeficiency virus (HIV) infection is increasingly frequent in industrialized countries...
  11. ncbi request reprint Use of well-defined HIV-derived epitopes to evaluate CD4(+) and CD8(+) T cell responses in patients with chronic HIV-1 infection treated with HAART
    Nathalie Daniel
    Department of Immunology, Cochin Institute, INSERM U567, CNRS UMR 8104, Rene Descartes University, Department of Internal Medicine, Cochin Hospital, Paris, France
    AIDS Res Hum Retroviruses 20:827-35. 2004
    ..In conclusion, the experimental approach used in this study shows that CD4(+) T cell responses may persist during HAART but are not associated with strong CD8(+) T cell responses..
  12. ncbi request reprint Predictive factors of response and survival in myelodysplastic syndrome treated with erythropoietin and G-CSF: the GFM experience
    Sophie Park
    Service d Hematologie, Hopital Cochin, Assistance Publique des Hopitaux de Paris, Universite Paris, France
    Blood 111:574-82. 2008
    ....
  13. doi request reprint Effect of sublingual administration of interferon-alpha on the immune response to influenza vaccination in institutionalized elderly individuals
    Odile Launay
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    Vaccine 26:4073-9. 2008
    ..At the dose tested sublingual administration of IFNalpha reduces the immune response to influenza vaccination in elderly institutionalized individuals...
  14. doi request reprint Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV
    Sophie Grabar
    INSERM U943, Bobigny, France
    AIDS 23:1163-9. 2009
    ..To estimate the prevalence and characteristics of long-term nonprogressor (LTNP) and HIV controller patients in a very large French cohort of HIV1-infected patients...
  15. doi request reprint Intracytoplasmic sperm injection with microsurgically retrieved spermatozoa in azoospermic men infected with human immunodeficiency virus 1 or hepatitis C virus: the EP43 AZONECO ANRS study
    Marianne Leruez-Ville
    Laboratoire de Virologie, Hopital Necker Enfants Malades, Assistance Publique de Paris, Universite Paris Descartes, Sorbonne Paris Cité, Paris, France
    Fertil Steril 99:713-7. 2013
    ....
  16. doi request reprint Bacteremia and MR-proANP changes in mild community-acquired pneumonia
    Solweig Guinard-Barbier
    Department of Emergency Medicine, Groupe Hospitalier Broca Cochin Hôtel Dieu, Paris, France
    Biomarkers 16:637-41. 2011
    ..Mid-regional pro-atrial natriuretic peptide (MR-proANP) increases with severity in community-acquired pneumonia (CAP). We investigated whether changes of MR-proANP correlated to bacteremia...
  17. doi request reprint Immunological efficacy of a three-dose schedule of hepatitis A vaccine in HIV-infected adults: HEPAVAC study
    Odile Launay
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    J Acquir Immune Defic Syndr 49:272-5. 2008
    ..The immunogenicity of vaccines, including vaccine against hepatitis A virus (HAV), is impaired in patients with HIV infection, requiring revised immunization regimens...
  18. ncbi request reprint The effect of erythropoietin on allogeneic blood requirement in patients undergoing elective liver resection: a model simulation
    Claude Lentschener
    Departments of Anesthesia and Critical Care, université Paris V René Descartes, Hopital Cochin, Paris, France
    Anesth Analg 98:921-6, table of contents. 2004
    ..02). rHuEPO administration to these 66 patients would have cost 186000 Euro. The 63 RBC saved would have cost 10,710 Euro...
  19. doi request reprint Do patients diagnosed with Alzheimer's disease benefit from a psycho-educational programme for family caregivers? A randomised controlled study
    Jocelyne De Rotrou
    Broca Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Int J Geriatr Psychiatry 26:833-42. 2011
    ....
  20. doi request reprint Accuracy of C-reactive protein, procalcitonin, and mid-regional pro-atrial natriuretic peptide to guide site of care of community-acquired pneumonia
    Yann Erick Claessens
    Department of Emergency Medicine, Hopital Cochin, APHP, 27 rue du Faubourg Saint Jacques, Paris Cedex 14, France
    Intensive Care Med 36:799-809. 2010
    ..The use at bedside of C-reactive protein (CRP), procalcitonin (PCT) or mid-regional pro-atrial natriuretic peptide (ANP) has been advocated to help management of patients with community-acquired pneumonia (CAP) in emergency medicine...
  21. doi request reprint Respective roles of acquired and congenital infections in presumed ocular toxoplasmosis
    Emmanuelle Delair
    Universite Paris Descartes, Faculte de Medecine, Service d Ophtalmologie, Hopital Cochin, Paris, France
    Am J Ophthalmol 146:851-5. 2008
    ..To analyze the roles of acquired or congenital infections in cases of ocular toxoplasmosis, and to compare their clinical manifestations...
  22. ncbi request reprint Cyclin E correlates with malignancy and adverse prognosis in adrenocortical tumors
    Frederique Tissier
    Service d Anatomie Pathologique, Hopital Cochin, AP HP, 75014 Paris, France
    Eur J Endocrinol 150:809-17. 2004
    ..In many cases, the prognosis of an adrenocortical tumor cannot be determined from pathologic findings alone. We investigated cyclin E levels as a potential marker...
  23. ncbi request reprint Plasma levels and expression of vascular endothelial growth factor-A in human localized prostate cancer
    Michael Peyromaure
    Department of Urology, Cichin Hospital, Paris, France
    Oncol Rep 18:145-9. 2007
    ..01). Our results suggest that the expression of VEGF may have a prognostic impact in clinically-localized PCa...
  24. ncbi request reprint Emergence of HIV-1 mutated strains after interruption of highly active antiretroviral therapy in chronically infected patients
    Nathalie Daniel
    AIDS 17:2126-9. 2003
  25. ncbi request reprint The changing incidence of AIDS events in patients receiving highly active antiretroviral therapy
    Antonella d'Arminio Monforte
    ICONA, Institute of Infectious and Tropical Diseases, University of Milan, Italy
    Arch Intern Med 165:416-23. 2005
    ....
  26. ncbi request reprint Incidence of Tuberculosis among HIV-infected patients receiving highly active antiretroviral therapy in Europe and North America
    Enrico Girardi
    Dipartimento di Epidemiologia, Istituto Nazionale per le Malattie Infettive L Spallanzani IRCCS, Via Portuense 292, 00149 Rome, Italy
    Clin Infect Dis 41:1772-82. 2005
    ..We obtained estimates of the incidence of tuberculosis (TB) among patients receiving HAART and identified determinants of the incidence...
  27. ncbi request reprint Long-term outcome of pediatric liver transplantation for biliary atresia: a 10-year follow-up in a single center
    Virginie Fouquet
    Department of Pediatric Surgery, Hopital Bicetre, Le Kremlin Bicetre, France
    Liver Transpl 11:152-60. 2005
    ..In conclusion, we discovered that a good long-term survival could be achieved after liver transplantation for BA, with a 82% survival rate at 10 years with normal scholastic studies in the majority of recipients...