Pierre Antoine Gourraud

Summary

Country: France

Publications

  1. ncbi Handling missing values in population data: consequences for maximum likelihood estimation of haplotype frequencies
    Pierre Antoine Gourraud
    Unité INSERM 558 Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Eur J Hum Genet 12:805-12. 2004
  2. ncbi Integration of microsatellite characteristics in the MHC region: a literature and sequence based analysis
    P A Gourraud
    INSERM unit 558, Toulouse, France
    Tissue Antigens 64:543-55. 2004
  3. ncbi Inferred HLA haplotype information for donors from hematopoietic stem cells donor registries
    Pierre Antoine Gourraud
    Faculty of Medicine, INSERM, Toulouse, France
    Hum Immunol 66:563-70. 2005
  4. ncbi Introduction to statistical analysis of population data in immunogenetics
    Pierre Antoine Gourraud
    Unite INSERM 558, Department of Epidemiology Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Transpl Immunol 14:245-53. 2005
  5. ncbi Preliminary analysis of a KIR haplotype estimation algorithm: a simulation study
    P A Gourraud
    INSERM U558, Department of Epidemiology, Faculty of Medicine, France
    Tissue Antigens 69:96-100. 2007
  6. ncbi A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for rheumatoid arthritis structural severity
    Pierre Antoine Gourraud
    INSERM U558, Toulouse, France
    Arthritis Rheum 54:593-9. 2006
  7. pmc A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis
    Pierre Antoine Gourraud
    Service d Epidémiologie CHU Toulouse, INSERM, U558, Universite Paul Sabatier Toulouse III, Faculte de Medecine, 37 Allees Jules Guesde, Toulouse Cedex 7, 31073, France
    Arthritis Res Ther 9:R27. 2007
  8. ncbi Strategies in analysis of the genetic component of multifactorial diseases; biostatistical aspects
    Thomas Barnetche
    Unite INSERM 558, Department of Epidemiology Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Transpl Immunol 14:255-66. 2005
  9. pmc IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients
    Nicolas Couturier
    INSERM U563, and Pôle des neurosciences, Université Toulouse 3, Toulouse, France
    Eur J Hum Genet 17:844-7. 2009
  10. pmc New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples
    Thomas Barnetche
    Department of Epidemiology and Public Health, UMR Inserm U 558, University Paul Sabatier Toulouse III, Faculty of Medicine Purpan, 37 Allees Jules Guesde, Toulouse Cedex 7, 31073, France
    Arthritis Res Ther 10:R26. 2008

Detail Information

Publications11

  1. ncbi Handling missing values in population data: consequences for maximum likelihood estimation of haplotype frequencies
    Pierre Antoine Gourraud
    Unité INSERM 558 Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Eur J Hum Genet 12:805-12. 2004
    ..We discuss the influence of missing values on the algorithm's efficiency and the advantages and disadvantages of deleting incomplete genotypes. We propose guidelines for missing data handling in routine analysis...
  2. ncbi Integration of microsatellite characteristics in the MHC region: a literature and sequence based analysis
    P A Gourraud
    INSERM unit 558, Toulouse, France
    Tissue Antigens 64:543-55. 2004
    ..The sequence of primers was corrected according to the consensus sequence. Table of synonymous names for individual microsatellite loci is provided...
  3. ncbi Inferred HLA haplotype information for donors from hematopoietic stem cells donor registries
    Pierre Antoine Gourraud
    Faculty of Medicine, INSERM, Toulouse, France
    Hum Immunol 66:563-70. 2005
    ..Limits and relevance of the method are related to limits of haplotype estimation. Relevance of the method is discussed in the context of HLA matching refinement...
  4. ncbi Introduction to statistical analysis of population data in immunogenetics
    Pierre Antoine Gourraud
    Unite INSERM 558, Department of Epidemiology Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Transpl Immunol 14:245-53. 2005
    ....
  5. ncbi Preliminary analysis of a KIR haplotype estimation algorithm: a simulation study
    P A Gourraud
    INSERM U558, Department of Epidemiology, Faculty of Medicine, France
    Tissue Antigens 69:96-100. 2007
    ..Large sample size studies are required using phase-known data and/or simulations. It would allow a genotype-based approach to explore the KIR gene haplotype diversity. The haplotype frequencies may be used to compare populations...
  6. ncbi A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for rheumatoid arthritis structural severity
    Pierre Antoine Gourraud
    INSERM U558, Toulouse, France
    Arthritis Rheum 54:593-9. 2006
    ..We investigated the relevance of this classification in terms of the structural severity of RA...
  7. pmc A new classification of HLA-DRB1 alleles differentiates predisposing and protective alleles for autoantibody production in rheumatoid arthritis
    Pierre Antoine Gourraud
    Service d Epidémiologie CHU Toulouse, INSERM, U558, Universite Paul Sabatier Toulouse III, Faculte de Medecine, 37 Allees Jules Guesde, Toulouse Cedex 7, 31073, France
    Arthritis Res Ther 9:R27. 2007
    ..The new classification of HLA-DRB1 SE+ alleles is relevant in terms of autoantibody production in early RA patients by differentiating predisposing and protective alleles for RF or ACPA production...
  8. ncbi Strategies in analysis of the genetic component of multifactorial diseases; biostatistical aspects
    Thomas Barnetche
    Unite INSERM 558, Department of Epidemiology Faculté de médecine, 37 Allees Jules Guesde, F 31073 Toulouse, France
    Transpl Immunol 14:255-66. 2005
    ..For this reason, in this article, we present the most important classical methodologies in genetic epidemiology of complex disorders. References and examples are given to illustrate...
  9. pmc IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients
    Nicolas Couturier
    INSERM U563, and Pôle des neurosciences, Université Toulouse 3, Toulouse, France
    Eur J Hum Genet 17:844-7. 2009
    ..45 and rs2068330, P=0.27). Similarly, no significant association was detected after stratification for HLA-DRB1*1501 carriers. Reasons that may explain this discrepancy between the original report and our study are discussed...
  10. pmc New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples
    Thomas Barnetche
    Department of Epidemiology and Public Health, UMR Inserm U 558, University Paul Sabatier Toulouse III, Faculty of Medicine Purpan, 37 Allees Jules Guesde, Toulouse Cedex 7, 31073, France
    Arthritis Res Ther 10:R26. 2008
    ..In the present study, we used RA samples collected worldwide to investigate the relevance of this new HLA-DRB1 classification in terms of RA susceptibility across various Caucasoid and non-Caucasoid patients...
  11. doi [Direct-to-consumer genetic testing through Internet: marketing, ethical and social issues]
    Pascal Ducournau
    INSERM U558, Épidémiologie et Analyses en Santé Publique, Risques, Maladies Chroniques, Handicaps, CUFR J F Champollion, Albi, France
    Med Sci (Paris) 27:95-102. 2011
    ..These three commercial strategies underlie various ethical and societal issues justifying a general analysis...