P Gorwood

Summary

Country: France

Publications

  1. ncbi [Comorbid addictions in bipolar disorder]
    P Gorwood
    AP-HP CHU Louis Mourier, , 178 rue des Renouillers, Colombes
    Encephale 34:S138-42. 2008
  2. ncbi Meeting everyday challenges: antipsychotic therapy in the real world
    Philip Gorwood
    AP HP, Hopital Louis Mourier, Colombes, France
    Eur Neuropsychopharmacol 16:S156-62. 2006
  3. ncbi Toxic effects of depression on brain function: impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients
    Philip Gorwood
    INSERM U675, Faculty of Medicine Bichat IFR02, 16 rue Henri Huchard, 75018 Paris, France
    Am J Psychiatry 165:731-9. 2008
  4. ncbi Neurobiological mechanisms of anhedonia
    Philip Gorwood
    INSERM U675, Institut Fédératif de Recherche IFR 02, Faculty Xavier Bichat, Paris, France
    Dialogues Clin Neurosci 10:291-9. 2008
  5. ncbi Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT2A receptor gene in patients with schizophrenia responsive to antipsychotics
    Dalila Benmessaoud
    Etablissement Hospitalier Spécialisé Psychiatrique M Boucebci Cheraga, Alger, Algeria
    BMC Psychiatry 8:40. 2008
  6. ncbi Gene-environment interactions in addictive disorders: epidemiological and methodological aspects
    Philip Gorwood
    INSERM U675, Institut Fédératif de Recherche IFR 02, Faculte Xavier Bichat, 16, rue Henri Huchard, 75018 Paris, France
    C R Biol 330:329-38. 2007
  7. ncbi Escitalopram prevents relapse in older patients with major depressive disorder
    Philip Gorwood
    From INSERM U675, Paris, France
    Am J Geriatr Psychiatry 15:581-93. 2007
  8. ncbi Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: association with the dopamine transporter gene (SLC6A3)
    D Purper-Ouakil
    AP HP, Robert Debre Hospital, Paris, France
    Am J Med Genet B Neuropsychiatr Genet 147:1425-30. 2008
  9. ncbi Lack of association of the dopamine transporter gene in a French ADHD sample
    M Wohl
    INSERM U 675, University Xavier Bichat IFR02, Paris, France
    Am J Med Genet B Neuropsychiatr Genet 147:1509-10. 2008
  10. ncbi Influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study
    M De Pradier
    INSERM U675 U894, Center of Psychiatry and Neurosciences, Paris, France
    Eur Psychiatry 25:323-7. 2010

Collaborators

Detail Information

Publications62

  1. ncbi [Comorbid addictions in bipolar disorder]
    P Gorwood
    AP-HP CHU Louis Mourier, , 178 rue des Renouillers, Colombes
    Encephale 34:S138-42. 2008
  2. ncbi Meeting everyday challenges: antipsychotic therapy in the real world
    Philip Gorwood
    AP HP, Hopital Louis Mourier, Colombes, France
    Eur Neuropsychopharmacol 16:S156-62. 2006
    ..Such naturalistic studies will continue to provide important data on the real-world effectiveness of atypical antipsychotics with respect to key outcomes such as treatment continuation and prolonged recovery...
  3. ncbi Toxic effects of depression on brain function: impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients
    Philip Gorwood
    INSERM U675, Faculty of Medicine Bichat IFR02, 16 rue Henri Huchard, 75018 Paris, France
    Am J Psychiatry 165:731-9. 2008
    ..The purpose of this study was to assess the generalizability of the impact of depression on hippocampal function...
  4. ncbi Neurobiological mechanisms of anhedonia
    Philip Gorwood
    INSERM U675, Institut Fédératif de Recherche IFR 02, Faculty Xavier Bichat, Paris, France
    Dialogues Clin Neurosci 10:291-9. 2008
    ....
  5. ncbi Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT2A receptor gene in patients with schizophrenia responsive to antipsychotics
    Dalila Benmessaoud
    Etablissement Hospitalier Spécialisé Psychiatrique M Boucebci Cheraga, Alger, Algeria
    BMC Psychiatry 8:40. 2008
    ....
  6. ncbi Gene-environment interactions in addictive disorders: epidemiological and methodological aspects
    Philip Gorwood
    INSERM U675, Institut Fédératif de Recherche IFR 02, Faculte Xavier Bichat, 16, rue Henri Huchard, 75018 Paris, France
    C R Biol 330:329-38. 2007
    ..e. more efficient, prevention strategies...
  7. ncbi Escitalopram prevents relapse in older patients with major depressive disorder
    Philip Gorwood
    From INSERM U675, Paris, France
    Am J Geriatr Psychiatry 15:581-93. 2007
    ..The present study investigated the efficacy and tolerability of escitalopram in the prevention of relapse of major depressive disorder (MDD) in older patients who had responded to acute treatment with escitalopram...
  8. ncbi Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: association with the dopamine transporter gene (SLC6A3)
    D Purper-Ouakil
    AP HP, Robert Debre Hospital, Paris, France
    Am J Med Genet B Neuropsychiatr Genet 147:1425-30. 2008
    ..28-0.76]). Heterogeneity between these studies did not reach a significant level but, as publications with different endpoints were excluded from this meta-analysis, our results do not rule out a possible influence of study design...
  9. ncbi Lack of association of the dopamine transporter gene in a French ADHD sample
    M Wohl
    INSERM U 675, University Xavier Bichat IFR02, Paris, France
    Am J Med Genet B Neuropsychiatr Genet 147:1509-10. 2008
    ..00 exactly, this possibility may be considered as not very likely...
  10. ncbi Influence of the serotonin transporter gene polymorphism, cannabis and childhood sexual abuse on phenotype of bipolar disorder: a preliminary study
    M De Pradier
    INSERM U675 U894, Center of Psychiatry and Neurosciences, Paris, France
    Eur Psychiatry 25:323-7. 2010
    ..The gene × environment interaction approach offers the opportunity to disentangle the latter, including childhood sexual abuse and cannabis abuse...
  11. ncbi Psychometric properties of a French version of the junior temperament and character inventory
    M Asch
    AP HP, Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, Paris, France
    Eur Child Adolesc Psychiatry 18:144-53. 2009
    ..Further studies are required to improve the psychometric properties of the child-rated JTCI, and to provide insight about lacking fit of our data with the theoretical model...
  12. ncbi Family-based association study of the serotonin-6 receptor gene (C267T polymorphism) in schizophrenia
    C Dubertret
    Service de Psychiatrie Adultes, Faculty of medicine Bichat Claude Bernard, Hôpital Louis Mourier AP HP, 178 rue des Renouillers, 92701 Colombes Cedex, France
    Am J Med Genet B Neuropsychiatr Genet 126:10-5. 2004
    ..These data do not support the idea that the 5-HT(6) receptor gene plays a major role in the etiopathogenesis of schizophrenia...
  13. ncbi Treatment response in major depression: effects of personality dysfunction and prior depression
    P Gorwood
    INSERM U675, CMME Sainte Anne Hospital, 100 rue de Santé, 75014 Paris, France
    Br J Psychiatry 196:139-42. 2010
    ..The impact of personality dysfunction on the outcome of treatment for depression remains debated...
  14. ncbi Rheumatoid arthritis and schizophrenia: a negative association at a dimensional level
    P Gorwood
    Hôpital Louis Mourier AP HP, Service de Psychiatrie, 178 rue des Renouillers, 92700 Colombes, France
    Schizophr Res 66:21-9. 2004
    ....
  15. ncbi Parental alcohol dependence, socioeconomic disadvantage and alcohol and cannabis dependence among young adults in the community
    M Melchior
    Inserm U1018, Centre for research in Epidemiology and Population Health, Epidemiology of Occupational and Social Determinants of Health, Hopital Paul Brousse, 16, avenue Paul Vaillant Couturier, 948070 Villejuif, France
    Eur Psychiatry 26:13-7. 2011
    ..8%) and cannabis dependence (DSM IV criteria, 7.3%) was doubled in the presence of combined parental alcohol dependence and socioeconomic disadvantage...
  16. ncbi Agomelatine, an innovative pharmacological response to unmet needs
    Y Le Strat
    INSERM U675, IFR02, Faculté de Médecine Xavier Bichat Université Paris, Paris, France
    J Psychopharmacol 22:4-8. 2008
    ..Furthermore, several randomized, double-blind, placebo-controlled and comparator-controlled studies of agomelatine in the treatment of major depressive disorder indicate that agomelatine is effective and well tolerated...
  17. ncbi Clinical characteristics of familial versus sporadic alcoholism in a sample of male and female patients
    F Limosin
    Service de Psychiatrie, Hopital Louis Mourier, 178 rue des Renouillers, 92701 Colombes Cedex, France
    Eur Psychiatry 16:151-6. 2001
    ....
  18. ncbi Predictors of diagnostic delay in a clinical sample of French children with attention-deficit/hyperactivity disorder
    D Purper-Ouakil
    AP HP, Hopital Robert Debre, Paris, France
    Eur Child Adolesc Psychiatry 16:505-9. 2007
    ....
  19. ncbi The CNR1 gene as a pharmacogenetic factor for antipsychotics rather than a susceptibility gene for schizophrenia
    Nora Hamdani
    AP HP, Hôpital Louis Mourier Paris VII, Service de Psychiatrie, 178 rue des Renouillers, 92700 Colombes, France
    Eur Neuropsychopharmacol 18:34-40. 2008
    ..The G allele of the CNR1 gene polymorphisms could be a psychopharmacogenetic rather than a vulnerability factor regarding schizophrenia and its treatment...
  20. ncbi Clinical and etiopathogenic specificities of the French concept of psychose hallucinatoire chronique compared to schizophrenia
    Caroline Dubertret
    INSERM U288, , Paris, France
    Schizophr Bull 30:173-84. 2004
    ..This study provides evidence that PHC may be a possible diagnosis in clinical practice, although it is difficult to reach a conclusion on its relationship with schizophrenia...
  21. ncbi The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia
    Caroline Dubertret
    Service de Psychiatrie Adulte, Faculty of Bichat Claude Bernard, Louis Mourier hospital AP HP, 178 rue des Renouillers, 92701 Colombes Cedex, France
    Schizophr Res 67:75-85. 2004
    ..As the analysis of the other markers within the DRD2 gene does not improve the strength of the association, our data are in favor of a specific role of the 3' chromosomic region of the DRD2 gene in the vulnerability to schizophrenia...
  22. ncbi A haplotype of the DRD1 gene is associated with alcohol dependence
    P Batel
    INSERM U675, Faculty of Medicine Bichat IFR02 Paris 7, Paris, France
    Alcohol Clin Exp Res 32:567-72. 2008
    ..The D1.1/r4532 marker of the DRD1 gene has been associated with a large set of phenotypes including addictive behaviors, but none with alcohol dependence per se...
  23. ncbi Meta-analysis of family-based association studies between the dopamine transporter gene and attention deficit hyperactivity disorder
    D Purper-Ouakil
    CHU Robert Debré AP HP, Paris VII, Paris, France
    Psychiatr Genet 15:53-9. 2005
    ..A recent meta-analysis showed that the DRD4 gene has a significant role in the vulnerability to ADHD...
  24. ncbi Paternal ages below or above 35 years old are associated with a different risk of schizophrenia in the offspring
    M Wohl
    INSERM U675, 16 rue Henri Huchard 75018 Paris, France
    Eur Psychiatry 22:22-6. 2007
    ..Defining a cut-off at which the risk is significantly increased in the offspring could have an important impact on public health...
  25. ncbi [Recurrent depression: episodes neurotoxicity and recurrences prevention]
    P Gorwood
    INSERM U894, Universite Paris Descartes, Centre de Psychiatrie et Neuroscience, CMME, Hopital Sainte Anne, Paris, France
    Encephale 36:S136-9. 2010
    ..This neurotoxicity hypothesis of major depressive disorder, apart from allowing a different way of communicating with our patients and to facilitate their compliance, strengthen the necessity to prevent recurrent depressive episodes...
  26. ncbi Association between age of onset and symptom profiles of late-life depression
    E Corruble
    Department of Psychiatry, Bicetre University Hospital, INSERM U 669, Paris XI University, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, France
    Acta Psychiatr Scand 118:389-94. 2008
    ..The recognition of later late-onset (LLO) major depression (MD) is a matter of concern...
  27. ncbi Lifetime positive symptoms in patients with schizophrenia and cannabis abuse are partially explained by co-morbid addiction
    Caroline Dubertret
    INSERM U675, Institut Fédératif de Recherche IFR 02, Faculty of Xavier Bichat 16 rue Henri Huchard, 75018 Paris, France
    Schizophr Res 86:284-90. 2006
    ..Distinguishing the effects of co-occurring addictive disorder(s) in patients with schizophrenia and cannabis dependence may thus be important when attempting to analyse the impact of cannabis abuse...
  28. ncbi Life events exposure before a treated major depressive episode depends on the number of past episodes
    Emmanuelle Corruble
    Department of Psychiatry, Assistance Publique Hopitaux de Paris, Bicetre University Hospital, INSERM U 669, Paris XI University, 78 rue du General Leclerc, 94230 Le Kremlin Bicêtre, France
    Eur Psychiatry 21:364-6. 2006
    ..A linear decline of average life events exposure is observed for more frequent past episodes, even when age, gender and severity are taken into account...
  29. ncbi [Neurobiology of attention deficit/hyperactivity disorder]
    Diane Purper-Ouakil
    INSERM U894, Centre de psychiatrie et Neurosciences, Equipe 1, Analyse génétique et clinique des comportements addictifs et psychiatriques, 2 ter, rue d Alesia, Paris, France
    Med Sci (Paris) 26:487-96. 2010
    ..Further insight into neurobiological mechanisms involved in ADHD will arise from collaborative networks and combination of imaging, genetic and neurobiological techniques with consideration of the developmental aspects of ADHD...
  30. ncbi A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes
    Caroline Dubertret
    INSERM U894 exU675, Center of Psychiatry and Neurosciences, Paris, France
    Prog Neuropsychopharmacol Biol Psychiatry 34:492-9. 2010
    ..However, genetic studies have yielded conflicting results whereas the promising TaqIA variant/rs1800497 has been mapped in a novel gene, ANKK1...
  31. ncbi Does lower response to alcohol explain the high co-morbidity between bipolar disorder and alcohol dependence?
    Y Le Strat
    INSERM U675, IFR02, Faculté de Médecine Xavier Bichat Université Paris 7, 16 rue Henri Huchard, 75018 Paris, France
    Med Hypotheses 71:81-4. 2008
    ..We discuss the neurobiological findings supporting our assumption, including the decreased reward-related brain activation in mania and further propose a brief study design to test this hypothesis...
  32. ncbi The genetics of addiction: alcohol-dependence and D3 dopamine receptor gene
    P Gorwood
    Hopital Louis Mourier, Service de Psychiatrie Adultes, 178, rue des Renouillers, 92700 Colombes, France
    Pathol Biol (Paris) 49:710-7. 2001
    ..There is good evidence that gene coding for the dopamine receptor D3 does not play a major role in the genetic vulnerability to alcoholism...
  33. ncbi Psychoeducation for patients with bipolar disorder receiving lithium: short and long term impact on locus of control and knowledge about lithium
    C Even
    Clinique des maladies mentales et de l Encéphale, Centre Hospitalier Sainte Anne, université Paris V René Descartes, Paris, France
    J Affect Disord 123:299-302. 2010
    ..Psychoeducation is now considered as part of the integrated treatment for bipolar disorder. But the psychological changes involved in it have been poorly studied...
  34. ncbi [Confusing clinical presentations and differential diagnosis of bipolar disorder]
    P Gorwood
    , Service de Psychiatrie, 178, rue des Renouillers, 92700 Colombes, Paris, France
    Encephale 30:182-93. 2004
    ..The assessment of mood cycling and their follow-up in adulthood may thus be particularly important. Lastly, presence of some anxious disorders may delay the diagnosis of comorbid bipolar disorder...
  35. ncbi Estrogen receptor 1 gene (ESR1) is associated with restrictive anorexia nervosa
    Audrey Versini
    INSERM U894 Team 1, Center of Psychiatry and Neurosciences, University Paris Descartes, 2ter rue d Alesia, Paris, France
    Neuropsychopharmacology 35:1818-25. 2010
    ..In particular, ESR1 gene confers a high risk of vulnerability to the restrictive subtype of AN, and suggests that the estrogen pathway has to be further analyzed in AN...
  36. ncbi Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism
    Gilles Maussion
    INSERM U675, IFR2, Faculte de Medecine Xavier Bichat, Universite Denis Diderot Paris 7, Paris, France
    Hum Mol Genet 17:2541-51. 2008
    ..As expected for a gene encoding a key polarity determinant Par-1 protein kinase, MARK1 is involved in axon-dendrite specification. Thus, MARK1 overexpression in humans may be responsible for subtle changes in dendritic functioning...
  37. ncbi A haplotype of the norepinephrine transporter (Net) gene Slc6a2 is associated with clinical response to atomoxetine in attention-deficit hyperactivity disorder (ADHD)
    Nicolas Ramoz
    INSERM U675, IFR02, Faculty Xavier Bichat, University of Paris, Paris, France
    Neuropsychopharmacology 34:2135-42. 2009
    ....
  38. ncbi Negative symptoms of schizophrenia could explain discrepant data on the association between the 5-HT2A receptor gene and response to antipsychotics
    Nora Hamdani
    Hôpital Louis Mourier AP HP, Service de Psychiatrie, 178 rue des Renouillers, 92700 Colombes, France
    Neurosci Lett 377:69-74. 2005
    ..This data indicate that negative symptoms are worth being systematically assessed in pharmacogenetic studies aimed at analysing candidate genes in schizophrenia...
  39. ncbi [Affective disorders and biological rhythms]
    Y Le Strat
    INSERM U675, IFR02, Faculte Xavier Bichat, Universite Paris VII, Paris, France
    Ann Pharm Fr 66:169-74. 2008
    ..Finally, all antidepressant medications could improve biological rhythms, but some new agents are now totally focusing this novel approach for the treatment of depression...
  40. ncbi Genetics and anorexia nervosa: a review of candidate genes
    P Gorwood
    Psychiatric Department, Hospital Louis Mourier, Colombes, France
    Psychiatr Genet 8:1-12. 1998
    ..Attention is paid to psychological dimensions, clinical symptoms, co-morbidity frequency, pharmacological data, and biological measures that characterize anorexia nervosa...
  41. ncbi SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects
    A M Lepagnol-Bestel
    INSERM U675, IFR2, Faculte de Medecine Xavier Bichat, Paris, France
    Mol Psychiatry 13:385-97. 2008
    ....
  42. ncbi [Criteria of remission in schizophrenia]
    P Gorwood
    INSERM U675, 16, rue Henri-Huchard, 75018 Paris, France
    Encephale 31:S18-20. 2005
  43. ncbi The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophrenia
    Yann Le Strat
    INSERM U675, Faculte de Medecine X Bichat, Universite Paris 7, Paris, France
    Curr Mol Med 9:506-18. 2009
    ..The literature supporting this gene x environment hypothesis is reviewed, with emphasis on some molecular pathways, raising the possibility to propose more specific molecular medicine...
  44. ncbi Association and excess of transmission of a DRD2 haplotype in a sample of French schizophrenic patients
    C Dubertret
    Service de Psychiatrie Adulte Pr ADES, Hôpital Louis Mourier AP HP, 178 rue des Renouillers, 92701 Cedex, Colombes, France
    Schizophr Res 49:203-12. 2001
    ..This haplotype may be more specifically involved in the disorder's onset at a later age in some patients, or, alternatively, may be implicated as a modifying factor acting on age of onset...
  45. ncbi Biological markers for suicidal behavior in alcohol dependence
    P Gorwood
    Hôpital Louis Mourier AP HP, Service de Psychiatrie, 178 rue des Renouillers, 92700 Colombes, France
    Eur Psychiatry 16:410-7. 2001
    ..Considering the complex but significant impact of alcohol on serotonin metabolism and turnover, it is likely that serotonin mediates a large part of the proneness of ethanol to commit impulsive-aggressive behavior...
  46. ncbi Eating disorders, serotonin transporter polymorphisms and potential treatment response
    Philip Gorwood
    Service de Psychiatrie, Hôpital Louis Mourier AP HP, 178 rue des Renouillers, 92700 Colombes, France
    Am J Pharmacogenomics 4:9-17. 2004
    ..SLC6A4 genotyping would allow physicians to individualize selective serotonin reuptake therapy for their patients...
  47. ncbi Temperament and character dimensions associated with clinical characteristics and treatment outcome in attention-deficit/hyperactivity disorder boys
    Diane Purper-Ouakil
    AP HP, Robert Debre Hospital, 75019 Paris, France
    Compr Psychiatry 51:286-92. 2010
    ....
  48. ncbi Reappraisal of the serotonin 5-HT(1B) receptor gene in alcoholism: of mice and men
    Philip Gorwood
    Hopital Louis Mourier, Service de Psychiatrie, Colombes, France
    Brain Res Bull 57:103-7. 2002
    ....
  49. ncbi Restoring circadian rhythms: a new way to successfully manage depression
    Philip Gorwood
    CMME, Hospital Sainte Anne, Paris, France
    J Psychopharmacol 24:15-9. 2010
    ..Together, these data suggest that agomelatine, through its innovative mechanism of action, may result in a more complete and sustained remission for chronically depressed patients...
  50. ncbi The A9 allele of the dopamine transporter gene is associated with delirium tremens and alcohol-withdrawal seizure
    Philip Gorwood
    Service de Psychiatrie, Hopital Louis Mourier, Assistance Publique Hopitaux de Paris AP HP, Colombes, France
    Biol Psychiatry 53:85-92. 2003
    ..Interestingly, an association was found between the DAT gene (9-copy repeat) and the risk for these symptoms in two previous case-control studies...
  51. ncbi Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders
    Fabrice Laroche
    INSERM Avenir, Institut Jacques Monod UMR7592, Paris, France
    Psychiatr Genet 18:295-301. 2008
    ..Our goal was to identify variations of coding trinucleotide repeats in schizophrenia, autism, and idiopathic mental retardation...
  52. ncbi Eating disorders: an overview of treatment responses and the potential impact of vulnerability genes and endophenotypes
    Nicolas Ramoz
    1INSERM U675, Universite Paris 7, IFR02, Faculte de Medecine Xavier Bichat, Paris, France
    Expert Opin Pharmacother 8:2029-44. 2007
    ....
  53. ncbi DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome
    Aude Marie Lepagnol-Bestel
    INSERM U675, IFR02, Faculte de Medecine Xavier Bichat, Universite Paris Diderot Paris 7, Paris, France
    Hum Mol Genet 18:1405-14. 2009
    ....
  54. ncbi [Role of genetics in psychiatric treatment]
    Nora Hamdani
    INSERM U675, Faculte Xavier Bichat, F 75018 Paris, France
    Presse Med 37:902-11. 2008
    ..Psychopharmacogenetic studies currently assess patients' capacity for acetylation or detoxification, coded by the NAT gene, whose genetic variants affect the metabolism of many psychotropic drugs...
  55. ncbi The 3' part of the dopamine transporter gene DAT1/SLC6A3 is associated with withdrawal seizures in patients with alcohol dependence
    Yann Le Strat
    INSERM U675, IFR02, Faculté de Médecine Xavier Bichat Université, Henri Huchard, Paris, France
    Alcohol Clin Exp Res 32:27-35. 2008
    ..We investigated whether polymorphisms within the DAT1 gene are associated with WS taking into account some of the confounding factors such as the severity of alcohol dependence...
  56. ncbi The short allele of the serotonin transporter promoter polymorphism influences relapse in alcohol dependence
    Emmanuel Pinto
    Department of Psychiatry, University of Liege, CHU Sart Tilman B35, B 4000 Liege, Belgium
    Alcohol Alcohol 43:398-400. 2008
    ..The short (S) allele of the serotonin transporter gene promoter polymorphism (5-HTTLPR) contributes to the risk of alcohol dependence and co-occurring clinical features. We studied the putative link between this allele and relapse...
  57. ncbi Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders
    Josep Maria Mercader
    Genes and Disease Program, Center for Genomic Regulation, 08003 Barcelona, Catalonia, Spain
    Hum Mol Genet 17:1234-44. 2008
    ..The reported data, in addition to the previous reported findings for BDNF and NTRK2, point neurotrophin signaling genes as key regulators of eating behavior and their altered cross-regulation as susceptibility factors for EDs...
  58. ncbi The A9 allele of the dopamine transporter gene increases the risk of visual hallucinations during alcohol withdrawal in alcohol-dependent women
    Frederic Limosin
    Department of Psychiatry, Albert Chenevier Hospital, 40 rue de Mesly, F 94000 Creteil, France
    Neurosci Lett 362:91-4. 2004
    ..Our results suggest that the A9 allele of the DAT gene is involved in vulnerability to alcohol withdrawal complications in women, but that these complications differ from those associated with this polymorphism in alcohol-dependent men...
  59. ncbi Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: the case of a subgroup of bipolar disorder with low suicide risk
    Beatrice Bonnier
    Hôpital Mignot, Service de Psychiatrie, Le Chesney, France
    Biol Psychiatry 51:762-5. 2002
    ..The implication of serotonin in suicide and affective disease explains why the 5-HT(2A) receptor gene has been proposed as a candidate gene in these disorders, although with conflicting results...
  60. ncbi Association between dopamine receptor D1 gene DdeI polymorphism and sensation seeking in alcohol-dependent men
    Frederic Limosin
    Department of Psychiatry, Albert Chenevier Hospital, France
    Alcohol Clin Exp Res 27:1226-8. 2003
    ..Moreover, it is suggested that higher levels of sensation seeking could be associated with a modification of sensitivity to dopamine in postsynaptic receptors...
  61. ncbi Family-based association study of the 5-HT transporter gene and schizophrenia
    Caroline Dubertret
    Service de Psychiatrie Adultes, Faculty of medicine Bichat Claude Bernard, Louis Mourier hospital AP HP, Colombes Cedex, France
    Int J Neuropsychopharmacol 8:87-92. 2005
    ..03). As the haplotype analyses did not improve the strength of the association, our data provide convergent evidence for a significant role of the 5-HTTLPR promoter polymorphism of the 5-HTT gene in the vulnerability to schizophrenia...
  62. ncbi Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset
    Roland M Dardennes
    Universite Paris Descartes, Faculte de Medecine, Hopital Sainte Anne, 1 rue Cabanis, 75674 Paris Cedex 14, France
    Psychoneuroendocrinology 32:106-13. 2007
    ....