Sylvain Glemin

Summary

Country: France

Publications

  1. doi request reprint Extinction and fixation times with dominance and inbreeding
    Sylvain Glemin
    Institut des Sciences de l Evolution de Montpellier, UMR 5554 CNRS CC64 Université Montpellier II, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    Theor Popul Biol 81:310-6. 2012
  2. pmc The erratic mitochondrial clock: variations of mutation rate, not population size, affect mtDNA diversity across birds and mammals
    Benoit Nabholz
    Université Montpellier 2 CNRS UMR 5554 Institut des Sciences de l Evolution Place E Bataillon CC064, Montpellier, France
    BMC Evol Biol 9:54. 2009
  3. pmc Surprising fitness consequences of GC-biased gene conversion. II. Heterosis
    Sylvain Glemin
    Institut des Sciences de l Evolution, Universite Montpellier II, 34095 Montpellier, France
    Genetics 187:217-27. 2011
  4. pmc Surprising fitness consequences of GC-biased gene conversion: I. Mutation load and inbreeding depression
    Sylvain Glemin
    Institut des Sciences de l Evolution, Universite Montpellier II, Montpellier 34095, France
    Genetics 185:939-59. 2010
  5. doi request reprint A comparative view of the evolution of grasses under domestication
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier 2, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    New Phytol 183:273-90. 2009
  6. pmc Patterns of inbreeding depression and architecture of the load in subdivided populations
    Sylvain Glemin
    Institut National de la Recherche Agronomique SGAP Montpellier, F 34130 Mauguio, France
    Genetics 165:2193-212. 2003
  7. doi request reprint Consequences of low mate availability in the rare self-incompatible species Brassica insularis
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier 2, France
    Conserv Biol 22:216-21. 2008
  8. pmc Mating systems and the efficacy of selection at the molecular level
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier II, 34095 Montpellier Cedex 5, France
    Genetics 177:905-16. 2007
  9. pmc Impact of mating systems on patterns of sequence polymorphism in flowering plants
    Sylvain Glemin
    UMR 5171 Genome, Populations, Interactions, Adaptation, Universite Montpellier II, 34095 Montpellier, France
    Proc Biol Sci 273:3011-9. 2006
  10. ncbi request reprint Marker-based investigation of inbreeding depression in the endangered species Brassica insularis
    S Glemin
    UMR Génome, Populations, Interactions, Adaptations, Universite Montpellier II, F 34095 Montpellier, Cedex 05, France
    Heredity (Edinb) 97:304-11. 2006

Collaborators

Detail Information

Publications29

  1. doi request reprint Extinction and fixation times with dominance and inbreeding
    Sylvain Glemin
    Institut des Sciences de l Evolution de Montpellier, UMR 5554 CNRS CC64 Université Montpellier II, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    Theor Popul Biol 81:310-6. 2012
    ..These findings extend previous results obtained for random mating populations and help clarifying previous simulation and numerical results on the effect of inbreeding on the dynamics of selected alleles...
  2. pmc The erratic mitochondrial clock: variations of mutation rate, not population size, affect mtDNA diversity across birds and mammals
    Benoit Nabholz
    Université Montpellier 2 CNRS UMR 5554 Institut des Sciences de l Evolution Place E Bataillon CC064, Montpellier, France
    BMC Evol Biol 9:54. 2009
    ..These properties make birds the ideal model to directly test for population size effects, and to discriminate between competing hypotheses about the causes of substitution rate variation...
  3. pmc Surprising fitness consequences of GC-biased gene conversion. II. Heterosis
    Sylvain Glemin
    Institut des Sciences de l Evolution, Universite Montpellier II, 34095 Montpellier, France
    Genetics 187:217-27. 2011
    ..To do so, I analyzed the infinite island model both by numerical computations and by analytical approximations. I showed that gBGC might have little impact on the total amount of heterosis but could greatly affect its genetic basis...
  4. pmc Surprising fitness consequences of GC-biased gene conversion: I. Mutation load and inbreeding depression
    Sylvain Glemin
    Institut des Sciences de l Evolution, Universite Montpellier II, Montpellier 34095, France
    Genetics 185:939-59. 2010
    ..These surprising results suggest that gBGC may have nonnegligible fitness consequences and could play a significant role in the evolution of genetic systems. They also shed light on the evolution of gBGC itself...
  5. doi request reprint A comparative view of the evolution of grasses under domestication
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier 2, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    New Phytol 183:273-90. 2009
    ..We close by suggesting future directions for the study of domestication in grasses...
  6. pmc Patterns of inbreeding depression and architecture of the load in subdivided populations
    Sylvain Glemin
    Institut National de la Recherche Agronomique SGAP Montpellier, F 34130 Mauguio, France
    Genetics 165:2193-212. 2003
    ..We also discuss the possible effects of migration and subdivision on the evolution of mating systems...
  7. doi request reprint Consequences of low mate availability in the rare self-incompatible species Brassica insularis
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier 2, France
    Conserv Biol 22:216-21. 2008
    ..Nevertheless, other populations also had reduced fruit set that could not be attributed to self-incompatibility alone...
  8. pmc Mating systems and the efficacy of selection at the molecular level
    Sylvain Glemin
    Institut des Sciences de l Evolution UM2 CNRS, Universite Montpellier II, 34095 Montpellier Cedex 5, France
    Genetics 177:905-16. 2007
    ..Different ways of testing these predictions are suggested, and implications of these results for the evolution of self-fertilizing species are also discussed...
  9. pmc Impact of mating systems on patterns of sequence polymorphism in flowering plants
    Sylvain Glemin
    UMR 5171 Genome, Populations, Interactions, Adaptation, Universite Montpellier II, 34095 Montpellier, France
    Proc Biol Sci 273:3011-9. 2006
    ..We show that among various life-history traits, mating systems have the greatest influence on patterns of polymorphism...
  10. ncbi request reprint Marker-based investigation of inbreeding depression in the endangered species Brassica insularis
    S Glemin
    UMR Génome, Populations, Interactions, Adaptations, Universite Montpellier II, F 34095 Montpellier, Cedex 05, France
    Heredity (Edinb) 97:304-11. 2006
    ..However, using molecular markers may give insight into the genetic basis of inbreeding depression, such as the occurrence of epistatic interactions among deleterious alleles or purging...
  11. ncbi request reprint Lethals in subdivided populations
    Sylvain Glemin
    UMR, CC63 Bat 24, Universite Montpellier II, Place Eugene Bataillon, 34095 Montpellier, France
    Genet Res 86:41-51. 2005
    ..These patterns are compared with those caused by mildly deleterious mutations to give a general picture of the effect of population structure on inbreeding depression, heterosis, and the mutation load...
  12. pmc Balancing selection in the wild: testing population genetics theory of self-incompatibility in the rare species Brassica insularis
    Sylvain Glemin
    UMR 5171 Genome, Populations, Interactions, Adaptations, Universite Montpellier II, F 34095 Montpellier, France
    Genetics 171:279-89. 2005
    ..insularis has a sporophytic SI system for which molecular markers are available. Our results match well the theoretical predictions and constitute the first general comparison of S-allele and neutral polymorphism...
  13. ncbi request reprint Population size does not influence mitochondrial genetic diversity in animals
    Eric Bazin
    CNRS UMR 5171 Génome, Populations, Interactions, Adaptation Université Montpellier 2 34095 Montpellier Cedex 5, France
    Science 312:570-2. 2006
    ..The unexpected mitochondrial diversity distribution is explained by recurrent adaptive evolution, challenging the neutral theory of molecular evolution and questioning the relevance of mtDNA in biodiversity and conservation studies...
  14. pmc Patterns and evolution of nucleotide landscapes in seed plants
    Laurana Serres-Giardi
    Institut des Sciences de l Evolution de Montpellier, Unite Mixte de Recherche 5554, Centre National de la Recherche Scientifique, Universite Montpellier 2, F 34095 Montpellier, France
    Plant Cell 24:1379-97. 2012
    ..Our results suggest that gBGC could play a significant role in the evolution of GC content in plant genomes...
  15. ncbi request reprint How are deleterious mutations purged? Drift versus nonrandom mating
    Sylvain Glemin
    UMR 1097 Diversité et Génome des Plantes Cultivées, INRA, Domaine de Melgueil, F 34130 Mauguio, France
    Evolution 57:2678-87. 2003
    ..The limitations derived here on the efficiency of purging are compatible with some experimental studies. Implications of these results for conservation and evolution of mating systems are discussed...
  16. doi request reprint GC-biased gene conversion promotes the fixation of deleterious amino acid changes in primates
    Nicolas Galtier
    Universite Montpellier 2, CNRS UMR 5554, Institut des Sciences de l Evolution, Place E Bataillon, CC64, 34095 Montpellier, France
    Trends Genet 25:1-5. 2009
    ..This demonstrates that gBGC has substantially (negatively) impacted the evolutionary trajectory of human proteins by promoting the fixation of deleterious AT-->GC mutations...
  17. doi request reprint GC-biased gene conversion and selection affect GC content in the Oryza genus (rice)
    Aline Muyle
    Institut des Sciences de l Evolution, UMR 5554 CNRS, Universite Montpellier II, France
    Mol Biol Evol 28:2695-706. 2011
    ..Our results suggest that both gBGC and selection on codon usage affect GC content in the Oryza genus and likely in other grass species...
  18. ncbi request reprint When genes go to sleep: the population genetic consequences of seed dormancy and monocarpic perenniality
    Renaud Vitalis
    Laboratoire Genetique et Environnement, C C 065, Institut des Sciences de l Evolution de Montpellier, Universite Montpellier II, 34095 Montpellier Cedex 05, France
    Am Nat 163:295-311. 2004
    ..We discuss our results in the light of recent population genetics surveys of annual plants with seed banks...
  19. doi request reprint GC-biased gene conversion impacts ribosomal DNA evolution in vertebrates, angiosperms, and other eukaryotes
    Juan S Escobar
    Institut des Sciences de l Evolution, Unité Mixte de Recherche 5554 Centre National de la Recherche Scientifique, Universite Montpellier II, Montpellier, France
    Mol Biol Evol 28:2561-75. 2011
    ..We extend analyses to major lineages of eukaryotes and suggest that gBGC might have also affected base composition in Giardia (Diplomonadina), nudibranch gastropods (Mollusca), and Asterozoa (Echinodermata)...
  20. pmc Bio++: a set of C++ libraries for sequence analysis, phylogenetics, molecular evolution and population genetics
    Julien Dutheil
    CNRS UMR 5171 Génome, Populations, Interactions, Adaptation GPIA, Universite Montpellier 2, France
    BMC Bioinformatics 7:188. 2006
    ..Such common features may be conveniently bundled into re-usable libraries, which enable the rapid development of new methods and robust applications...
  21. doi request reprint An integrative test of the dead-end hypothesis of selfing evolution in Triticeae (Poaceae)
    Juan S Escobar
    Institut National de la Recherche Agronomique, Centre de Montpellier, UMR Diversité et Adaptation des Plantes Cultivées, Domaine de Melgueil, Mauguio, France
    Evolution 64:2855-72. 2010
    ..We suggest that, in Triticeae, although recombination patterns have remained stable, selfing lineages are of recent origin and inbreeding may have persisted for insufficient time for differences between the two mating systems to evolve...
  22. ncbi request reprint Strong variations of mitochondrial mutation rate across mammals--the longevity hypothesis
    Benoit Nabholz
    Institut des Sciences de l Evolution CC64, Centre National de la Recherche Scientifique Université Montpellier 2, Montpellier, France
    Mol Biol Evol 25:120-30. 2008
    ..We propose that natural selection tends to decrease the mitochondrial mutation rate in long-lived species, in agreement with the mitochondrial theory of aging...
  23. doi request reprint Complexity, pleiotropy, and the fitness effect of mutations
    João Lourenço
    Université Montpellier II CNRS UMR 5554 Institut des Sciences de l Evolution Montpellier, France
    Evolution 65:1559-71. 2011
    ..We discuss the plausibility of the model...
  24. pmc Determination of mitochondrial genetic diversity in mammals
    Benoit Nabholz
    CNRS UMR 5554 Institut des Sciences de l Evolution, Montpellier, France
    Genetics 178:351-61. 2008
    ..They suggest that, even in the absence of selection, mtDNA genetic diversity is essentially unpredictable, knowing species biology, and probably uncorrelated to species abundance...
  25. pmc Reference-free population genomics from next-generation transcriptome data and the vertebrate-invertebrate gap
    Philippe Gayral
    Universite Montpellier 2, CNRS UMR 5554, Institut des Sciences de l Evolution de Montpellier, Montpellier, France
    PLoS Genet 9:e1003457. 2013
    ..This study opens promising perspective regarding genome-wide population analyses of non-model organisms and the influence of population size on non-synonymous versus synonymous diversity...
  26. doi request reprint Adaptation and maladaptation in selfing and outcrossing species: new mutations versus standing variation
    Sylvain Glemin
    Institut des Sciences de l Evolution de Montpellier, UMR 5554 CNRS, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    Evolution 67:225-40. 2013
    ..Our results bear implications for the evolution of the selfing syndrome, the dynamics of the domestication process, and the dead-end hypothesis that posits that selfing lineages are doomed to extinction on the long run...
  27. doi request reprint The rate of molecular adaptation in a changing environment
    João M Lourenço
    Universite Montpellier 2, CNRS UMR 5554, Institut des Sciences de l Évolution Place E Bataillon, CC64, Montpellier, France
    Mol Biol Evol 30:1292-301. 2013
    ..We discuss the reasons why verbal arguments have been misleading on that subject and revisit the empirical evidence. Our results question the relevance of the "α" parameter as an indicator of the efficiency of molecular adaptation...
  28. pmc Mitochondrial whims: metabolic rate, longevity and the rate of molecular evolution
    Nicolas Galtier
    Institut des Sciences de l Evolution, CNRS UMR 5554, Universite Montpellier 2, Place E Bataillon, 34095 Montpellier, France
    Biol Lett 5:413-6. 2009
    ..We suggest that natural selection could act to reduce the (somatic) mtDNA mutation rate in long-lived species, in agreement with the mitochondrial theory of ageing...
  29. doi request reprint Genome evolution in outcrossing versus selfing versus asexual species
    Sylvain Glemin
    Institut des Sciences de l Evolution, UMR5554, Universite Montpellier II, Montpellier, France
    Methods Mol Biol 855:311-35. 2012
    ..We discuss the possible reasons to potentially explain this paradox. In reverse, comparative and population genomic data and approaches help revisiting old questions on the long-term evolution of breeding systems...