Jean Antoine Girault

Summary

Country: France

Publications

  1. pmc Nodes of ranvier and paranodes in chronic acquired neuropathies
    Carmen Cifuentes-Diaz
    Institut National de la Sante et de la Recherche Medicale, Unité Mixte de Recherche en Santé 839, Paris, France
    PLoS ONE 6:e14533. 2011
  2. ncbi request reprint The neurobiology of dopamine signaling
    Jean Antoine Girault
    Institut National de la Santé et de la Recherche Médicale and Université Pierre et Marie Curie Unit 536, Institut du Fer a Moulin, Paris, France
    Arch Neurol 61:641-4. 2004
  3. ncbi request reprint ERK2: a logical AND gate critical for drug-induced plasticity?
    Jean Antoine Girault
    INSERM, UMR S536, F 75005, Paris, France
    Curr Opin Pharmacol 7:77-85. 2007
  4. doi request reprint Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol
    Jesus Bertran-Gonzalez
    Inserm UMR S 839, Paris, France
    J Neurosci 28:5671-85. 2008
  5. pmc Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol
    Emmanuel Valjent
    Inserm UMR S 839, Paris, France
    Neuropsychopharmacology 35:401-15. 2010
  6. ncbi request reprint Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus
    Pascal Derkinderen
    Institut National de la Santé et de la Recherche Médicale Université Pierre et Marie Curie U536, Institut du Fer a Moulin, Paris, France 75005
    J Neurosci 23:2371-82. 2003
  7. ncbi request reprint Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants
    Jean Christophe Corvol
    INSERM, U536, Paris, France
    Neuropsychopharmacology 32:1109-21. 2007
  8. pmc Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
    Emmanuel Valjent
    Institut National de la Santé et de la Recherche Médicale and Université Pierre et Marie Curie U536, Signal Transduction and Plasticity in the Nervous System, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    Proc Natl Acad Sci U S A 102:491-6. 2005
  9. ncbi request reprint PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation
    Gress Kadaré
    INSERM UPMC U536, Institut National de la Santé et de la Recherche Médicale et Université Pierre et Marie Curie, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    J Biol Chem 278:47434-40. 2003
  10. doi request reprint Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation
    Vincent Pascoli
    Centre National de la Recherche Scientifique Unite Mixte de Recherche, Paris, France
    Biol Psychiatry 69:218-27. 2011

Collaborators

Detail Information

Publications65

  1. pmc Nodes of ranvier and paranodes in chronic acquired neuropathies
    Carmen Cifuentes-Diaz
    Institut National de la Sante et de la Recherche Medicale, Unité Mixte de Recherche en Santé 839, Paris, France
    PLoS ONE 6:e14533. 2011
    ..Marked differences were observed between CIDP and CIAP and the alterations in paranodin immunofluorescence may be an interesting tool for their differential diagnosis...
  2. ncbi request reprint The neurobiology of dopamine signaling
    Jean Antoine Girault
    Institut National de la Santé et de la Recherche Médicale and Université Pierre et Marie Curie Unit 536, Institut du Fer a Moulin, Paris, France
    Arch Neurol 61:641-4. 2004
    ..Recent findings allow us to identify molecules that may represent future therapeutic targets in neurology and psychiatry...
  3. ncbi request reprint ERK2: a logical AND gate critical for drug-induced plasticity?
    Jean Antoine Girault
    INSERM, UMR S536, F 75005, Paris, France
    Curr Opin Pharmacol 7:77-85. 2007
    ..We suggest that the ERK2 pathway acts as a logical AND gate, permissive for plasticity, in neurons on which dopamine-mediated reward signals and glutamate-mediated contextual information converge...
  4. doi request reprint Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol
    Jesus Bertran-Gonzalez
    Inserm UMR S 839, Paris, France
    J Neurosci 28:5671-85. 2008
    ....
  5. pmc Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol
    Emmanuel Valjent
    Inserm UMR S 839, Paris, France
    Neuropsychopharmacology 35:401-15. 2010
    ..It provides a simple and sensitive paradigm to study the mechanisms of long-term effects of drugs of abuse...
  6. ncbi request reprint Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus
    Pascal Derkinderen
    Institut National de la Santé et de la Recherche Médicale Université Pierre et Marie Curie U536, Institut du Fer a Moulin, Paris, France 75005
    J Neurosci 23:2371-82. 2003
    ....
  7. ncbi request reprint Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants
    Jean Christophe Corvol
    INSERM, U536, Paris, France
    Neuropsychopharmacology 32:1109-21. 2007
    ....
  8. pmc Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
    Emmanuel Valjent
    Institut National de la Santé et de la Recherche Médicale and Université Pierre et Marie Curie U536, Signal Transduction and Plasticity in the Nervous System, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    Proc Natl Acad Sci U S A 102:491-6. 2005
    ....
  9. ncbi request reprint PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation
    Gress Kadaré
    INSERM UPMC U536, Institut National de la Santé et de la Recherche Médicale et Université Pierre et Marie Curie, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    J Biol Chem 278:47434-40. 2003
    ..These observations show that sumoylation controls the activity of a protein kinase and suggest that FAK may play a novel role in signaling between the plasma membrane and the nucleus...
  10. doi request reprint Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation
    Vincent Pascoli
    Centre National de la Recherche Scientifique Unite Mixte de Recherche, Paris, France
    Biol Psychiatry 69:218-27. 2011
    ..However, the mechanisms responsible for this activation, especially the respective contribution of D1R and NMDAR, remain unknown...
  11. ncbi request reprint Association of Caspr/paranodin with tumour suppressor schwannomin/merlin and beta1 integrin in the central nervous system
    Natalia Denisenko-Nehrbass
    INSERM UPMC U536, Institut du Fer a Moulin, Paris, France
    J Neurochem 84:209-21. 2003
    ..Since integrin beta1 and schwannomin do not appear to be enriched in paranodes they may be quantitatively minor partners of paranodin in these regions and/or be associated with paranodin at other locations...
  12. pmc A phosphatase cascade by which rewarding stimuli control nucleosomal response
    Alexandre Stipanovich
    INSERM, UMR S 839, 75005 Paris, France
    Nature 453:879-84. 2008
    ..Mutation of Ser 97 profoundly alters behavioural effects of drugs of abuse and decreases motivation for food, underlining the functional importance of this signalling cascade...
  13. ncbi request reprint Depolarization activates ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal slices
    Jean Christophe Corvol
    Signal Transduction and Plasticity in the Nervous System Unit, INSERM Université Pierre et Marie Curie U536, Institut du Fer a Moulin, 75005 Paris, France
    J Biol Chem 280:660-8. 2005
    ....
  14. ncbi request reprint Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain
    Emmanuel Valjent
    Signal Transduction and Plasticity in the Nervous System, INSERM UPMC U536, Institut du Fer a Moulin, Paris, France
    Eur J Neurosci 19:1826-36. 2004
    ....
  15. pmc Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference
    Emmanuel Valjent
    Institut National de la Sante et de la Recherche Medicale, U536, Paris, France
    Proc Natl Acad Sci U S A 103:2932-7. 2006
    ..These results suggest potential therapeutic strategies to explore in the context of addiction...
  16. doi request reprint Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation
    Camille Faure
    INSERM, UMR S 839, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005, Paris, France
    Cell Mol Life Sci 70:137-52. 2013
    ..Our results elucidate the mechanisms of Ca(2+)-induced nuclear accumulation of Pyk2. They also suggest that Pyk2 nuclear accumulation is a novel type of signaling response that may contribute to specific long-term adaptations in neurons...
  17. doi request reprint Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia
    Jean Antoine Girault
    Institut du Fer a Moulin, Paris, France
    Prog Mol Biol Transl Sci 106:33-62. 2012
    ..It is hypothesized that these pathways are particularly adapted to the specific computing properties of MSNs and the function of the basal ganglia circuits in which they participate...
  18. ncbi request reprint Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres
    Natalia Denisenko-Nehrbass
    INSERM UPMC U536, Institut du Fer a Moulin, 17, rue du Fer à Moulin, 75005 Paris, France
    Eur J Neurosci 17:411-6. 2003
    ..Our results provide strong evidence for the association of 4.1B with Caspr/paranodin at paranodes and with Caspr2 at juxtaparanodes. We propose that 4.1B anchors these axonal proteins to the actin-based cytoskeleton in these two regions...
  19. ncbi request reprint cAMP and extracellular signal-regulated kinase signaling in response to d-amphetamine and methylphenidate in the prefrontal cortex in vivo: role of beta 1-adrenoceptors
    Vincent Pascoli
    INSERM UPMC UMR 536, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    Mol Pharmacol 68:421-9. 2005
    ..This activation could have behavioral consequences and contribute to the treatment of attention-deficit/hyperactivity disorder...
  20. doi request reprint Integrating neurotransmission in striatal medium spiny neurons
    Jean Antoine Girault
    Institut du Fer a Moulin, UMR S 839, INSERM and Université Pierre et Marie Curie, 17 Rue du Fer a Moulin, 75005 Paris, France
    Adv Exp Med Biol 970:407-29. 2012
    ....
  21. pmc Role of the ERK pathway in psychostimulant-induced locomotor sensitization
    Emmanuel Valjent
    INSERM, U536, F 75005, Université Pierre et Marie Curie UPMC Paris 6, F 75005, Paris
    BMC Neurosci 7:20. 2006
    ....
  22. ncbi request reprint Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants
    Anne Gaëlle Corbillé
    INSERM, U839, F 75005 Paris, France
    J Neurosci 27:6937-47. 2007
    ....
  23. pmc Protein 4.1B contributes to the organization of peripheral myelinated axons
    Carmen Cifuentes-Diaz
    INSERM, UMR S 839, Paris, France
    PLoS ONE 6:e25043. 2011
    ..Thus, our results show that in myelinated axons 4.1B contributes to the stabilization of membrane proteins at paranodes, to the clustering of juxtaparanodal proteins, and to the regulation of the internodal axon caliber...
  24. doi request reprint Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice
    Emmanuel Valjent
    INSERM, UMR S 839, 75005 Paris, France
    Trends Neurosci 32:538-47. 2009
    ..Thus, BAC transgenic mice are changing the way to conceive experiments and provide an opportunity to fill the gaps between molecular and systems neurosciences...
  25. pmc Syndecan-3 and syndecan-4 are enriched in Schwann cell perinodal processes
    Laurence Goutebroze
    INSERM U536, UPMC, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    BMC Neurosci 4:29. 2003
    ..The aim of this study is to identify by immunocytochemistry transmembrane proteins enriched in Schwann cells processes that could interact, directly or indirectly, with axonal proteins...
  26. pmc Alternative splicing controls the mechanisms of FAK autophosphorylation
    Madeleine Toutant
    INSERM UPMC U536, Institut du Fer a Moulin, 75005 Paris, France
    Mol Cell Biol 22:7731-43. 2002
    ..Our results clarify the mechanisms of FAK activation and show how alternative splicing can dramatically alter the mechanism of autophosphorylation of a protein kinase...
  27. pmc Striatal medium-sized spiny neurons: identification by nuclear staining and study of neuronal subpopulations in BAC transgenic mice
    Miriam Matamales
    Inserm UMR S 839, Paris, France
    PLoS ONE 4:e4770. 2009
    ..It also unambiguously confirms the degree of segregation of MSNs in the mouse striatum and allows the full exploitation of results obtained with BAC-transgenic mice...
  28. ncbi request reprint A molecular view on paranodal junctions of myelinated fibers
    Natalia Denisenko-Nehrbass
    INSERM U536, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    J Physiol Paris 96:99-103. 2002
    ..Thus, paranodin plays a central role in the assembly of multiprotein complexes necessary for the formation and maintenance of paranodal junctions...
  29. ncbi request reprint [Cellular contacts in myelinated fibers of the peripheral nervous system]
    Ksenia Oguievetskaia
    Laboratoire de transduction du signal et plasticité dans le système nerveux, Inserm U 536 et Université Pierre et Marie Curie, Institut du Fer a Moulin, 17, rue du Fer à Moulin, 75005 Paris, France
    Med Sci (Paris) 21:162-9. 2005
    ..Understanding more precisely their molecular basis now appears essential as a requisite step to further examine their involvement in the pathogenesis of peripheral neuropathies in general...
  30. doi request reprint FAK dimerization controls its kinase-dependent functions at focal adhesions
    Karen Brami-Cherrier
    Inserm UMR S839, Paris, France
    EMBO J 33:356-70. 2014
    ..Our results provide a structural and mechanistic framework to explain how FAK combines multiple stimuli into a site-specific function. The dimer interfaces we describe are promising targets for blocking FAK activation...
  31. ncbi request reprint Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease
    Jean Christophe Corvol
    Institut National de la Santé et de la Recherche Médicale Université Pierre et Marie Curie Unité 536, Institut du Fer a Moulin, 75005 Paris, France
    J Neurosci 24:7007-14. 2004
    ..In conclusion, our results revealed in the parkinsonian putamen a prolonged elevation of Galphaolf levels that may lead to a persistent D1 receptor hypersensitivity and contribute to the genesis of long-term complications of L-dopa...
  32. ncbi request reprint Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments
    Pierre Marie Martin
    Unité Mixte de Recherche S 839, INSERM, Universite Pierre et Marie Curie, Institut du Fer a Moulin, Paris 75005, France
    J Neurosci 28:6111-7. 2008
    ..We suggest that IQCJ-SCHIP-1 might participate, along with AnkG and betaIV-spectrin, in the stabilization or function of the multimolecular complexes of AISs and NRs, possibly by participating in Ca(2+)-mediated responses...
  33. doi request reprint Role of the ERK/MSK1 signalling pathway in chromatin remodelling and brain responses to drugs of abuse
    Karen Brami-Cherrier
    UMR 7102, CNRS, Laboratoire de Neurobiologie des Processus Adaptatifs, corrected Université Pierre et Marie Curie Paris 6, Paris, France
    J Neurochem 108:1323-35. 2009
    ..Thus, ERK plays a dual role in gene regulation and drug addiction by direct activation of transcription factors and by chromatin remodelling...
  34. ncbi request reprint Development of nodes of Ranvier
    Jean Antoine Girault
    INSERM U 536, Institut du Fer a Moulin, 17 Rue du Fer a Moulin, 75005 Paris, France
    Curr Opin Neurobiol 12:476-85. 2002
    ....
  35. doi request reprint Transient and rapid activation of Akt/GSK-3β and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens
    Marie Josèphe Salles
    Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
    J Neurochem 125:532-44. 2013
    ..This effect may contribute to the influence of D3R ligands on reward, cognition, and processes disrupted in schizophrenia, drug abuse, and Parkinson's disease...
  36. ncbi request reprint Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons
    Camille Faure
    INSERM, U839, Paris F 75005, France
    J Cell Sci 120:3034-44. 2007
    ..We suggest that PYK2 exerts some of its actions in the nucleus and that the effects of calcineurin inhibitors may involve PYK2 inhibition...
  37. ncbi request reprint FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3
    Lucilla Bongiorno-Borbone
    INSERM, U536, Paris, France
    Biochem Biophys Res Commun 337:641-6. 2005
    ..Our results suggest that SAPAP3 is an anchoring protein for FAK and PYK2 in post-synaptic densities and may contribute to the synaptic function of these tyrosine kinases...
  38. doi request reprint Role of the plasticity-associated transcription factor zif268 in the early phase of instrumental learning
    Matthieu Maroteaux
    Inserm UMR S 839, Paris, France Université Pierre et Marie Curie, Paris, France Institut du Fer à Moulin, Paris, France
    PLoS ONE 9:e81868. 2014
    ..In conclusion, Zif268 participates in the processes underlying performance and motivation to execute food-conditioned instrumental task. ..
  39. ncbi request reprint Transmembrane scaffolding proteins in the formation and stability of nodes of Ranvier
    Jean Antoine Girault
    Signal Transduction and Plasticity in the Nervous, System Institut National de la Santé et de la Recherche Médicale and Université Pierre et Marie Curie, INSERM UPMC U536, Institut du Fer a Moulin, rue du Fer à Moulin, Paris, France
    Biol Cell 95:447-52. 2003
    ....
  40. pmc Organization and post-transcriptional processing of focal adhesion kinase gene
    Jean Marc Corsi
    Unité Mixte de Recherche Santé UMR S 536, Institut National de la Santé et de la Recherche Médicale INSERM F 75005, Paris, France
    BMC Genomics 7:198. 2006
    ..Here, we study the phylogeny of FAK, the organization of its gene, and its post-transcriptional processing in rodents and human...
  41. pmc Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons
    Jesus Bertran-Gonzalez
    INSERM, UMR S 839, Paris, France
    Neuropsychopharmacology 34:1710-20. 2009
    ..Thus, blockade of D2Rs promotes histone H3 phosphorylation through the A2AR-mediated activation of Galpha(olf) and inhibition of protein phosphatase-1 (PP-1) through the PKA-dependent phosphorylation of DARPP-32...
  42. ncbi request reprint Fluorescence-activated sorting of fixed nuclei: a general method for studying nuclei from specific cell populations that preserves post-translational modifications
    Lucile Marion-Poll
    Inserm UMR S 839, Paris, France Université Pierre and Marie Curie, Sorbonne Universités, Paris, France Institut du Fer à Moulin, Paris, France
    Eur J Neurosci 39:1234-44. 2014
    ..FAST-FIN allows the preservation and study of dynamic and labile post-translational protein modifications. It should be applicable to other tissues and species, and allow study of DNA and its modifications. ..
  43. doi request reprint Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32
    Natalia Sánchez
    Millennium Nucleus in Stress and Addiction NEDA, Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Pontificia Universidad Catolica de Chile, Chile Inserm, UMR S 839, Paris, France Université Pierre et Marie Curie UPMC, Paris, France Institut du Fer à Moulin, Paris, France
    Neuropharmacology 79:559-66. 2014
    ..Our results clarify the mechanisms of Nur77 induction by antipsychotic and its possible contribution to extrapyramidal effects. ..
  44. doi request reprint Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves
    Natalia Denisenko
    INSERM, Unité Mixte de Recherche en Santé 839, Paris, 75005, France
    J Neurosci 28:10472-81. 2008
    ..Thus, schwannomin plays an important role in the control of Schwann cell number and is necessary for the correct organization and regulation of axoglial heterotypic and glio-glial autotypic contacts...
  45. doi request reprint Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia
    Cristina Alcacer
    Inserm UMR S 839, F 75005 Paris, France
    J Neurosci 32:5900-10. 2012
    ..In contrast, the persistence of L-DOPA-induced ERK activation in Gnal⁺/⁻ mice supports its causal role in LID development...
  46. pmc Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers
    Maria Traka
    Department of Basic Science, University of Crete Medical School, Heraklion 71110, Crete, Greece
    J Cell Biol 162:1161-72. 2003
    ..This complex is analogous to that described previously at paranodes, suggesting that similar molecules are crucial for different types of axo-glial interactions...
  47. ncbi request reprint The paranodal complex of F3/contactin and caspr/paranodin traffics to the cell surface via a non-conventional pathway
    Carine Bonnon
    Neurobiologie des Interactions Cellulaires et Neuropathologie, FRE 2533 CNRS, Institut Jean Roche, 13916 Marseille, France
    J Biol Chem 278:48339-47. 2003
    ..Our results indicate a Golgi-independent pathway for the paranodal cell adhesion complex that may be implicated in the segregation of axonal subdomains...
  48. ncbi request reprint Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice
    Karen Brami-Cherrier
    Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie, Unite Mixte de Recherche 7102, 75005 Paris, France
    J Neurosci 25:11444-54. 2005
    ..Our results show that MSK1 is a major striatal kinase, downstream from ERK, responsible for the phosphorylation of CREB and H3 and is required specifically for the induction of c-Fos and dynorphin as well as for locomotor sensitization...
  49. ncbi request reprint DARPP-32: an integrator of neurotransmission
    Per Svenningsson
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Annu Rev Pharmacol Toxicol 44:269-96. 2004
    ....
  50. ncbi request reprint The role of DARPP-32 in the actions of drugs of abuse
    Angus C Nairn
    Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA
    Neuropharmacology 47:14-23. 2004
    ..This review focuses on the critical role that DARPP-32 plays in mediating the actions of a broad range of drugs of abuse...
  51. ncbi request reprint Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment
    Hélène Rangone
    UMR 146 CNRS Institut Curie, Centre Universitaire, 91405 Orsay Cedex, France
    J Biol Chem 280:22021-8. 2005
    ..This study points out a new mechanism by which Akt promotes neuroprotection in HD, emphasizing the potential therapeutic interest of this pathway in the disease...
  52. ncbi request reprint F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination
    Julien Falk
    Neurogenèse et Morphogenèse dans Développement et chez l Adulte, UMR 6156, IBDM, Marseille, France
    Biol Cell 94:327-34. 2002
    ..Finally, the recent identification of a Drosophila homologue of F3/contactin indicated that this family of GPI-anchored CAMs plays a conserved function in axonal insulation...
  53. ncbi request reprint Plasticity-associated gene Krox24/Zif268 is required for long-lasting behavioral effects of cocaine
    Emmanuel Valjent
    Institut National de la Sante et de la Recherche Medicale, Unité 536, F 75005 Paris, France
    J Neurosci 26:4956-60. 2006
    ..They also underline the common molecular machinery involved in long-lasting drug-induced behavioral alterations and the formation of other types of memory...
  54. ncbi request reprint Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia
    Emanuela Santini
    Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden
    J Neurosci 27:6995-7005. 2007
    ....
  55. ncbi request reprint Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction
    Perrine Charles
    INSERM U 495, Biologie des Interactions Neurones Glie, UPMC, Hopital de la Salpetriere, 75651 Paris Cedex 13, France
    Curr Biol 12:217-20. 2002
    ..These results demonstrate that the paranodin/Caspr-contactin complex interacts biochemically with NF155 and that this interaction is likely to be biologically relevant at the axoglial junction...
  56. ncbi request reprint [Paranodal junctions of myelinated fibers: site of anchorage and interactions]
    Catherine Lubetzki
    Med Sci (Paris) 19:22-4. 2003
  57. ncbi request reprint Adenylate cyclase 1 as a key actor in the refinement of retinal projection maps
    Anne Ravary
    Institut National de la Santé et de la Recherche Médicale Unite 106, Hopital Pitie Salpetriere, 75651 Paris, France
    J Neurosci 23:2228-38. 2003
    ..Calcium-modulated cAMP production in the RGCs could constitute an important link between activity-dependent changes and the anatomical restructuring of the retinal terminal arbors within central targets...
  58. ncbi request reprint The translocation of focal adhesion kinase in brain synaptosomes is regulated by phosphorylation and actin assembly
    Lucilla Bongiorno-Borbone
    Department of Experimental Medicine, Section of Human Physiology, University of Genova, Viale Benedetto, Genova, Italy
    J Neurochem 81:1212-22. 2002
    ....
  59. ncbi request reprint Focal adhesion kinase pp125FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: potential role in mechanotransduction
    Roger Rezzonico
    Faculte de Medecine, INSERM U364, Nice, France
    J Bone Miner Res 18:1863-71. 2003
    ..We show that the mechanosensitive BK channels open and recruit the focal adhesion kinase FAK in osteoblasts on hypotonic shock. This could convert mechanical signals in biochemical events, leading to osteoblast activation...
  60. ncbi request reprint Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin
    Samantha Messina
    Department of Experimental Medicine, Section of Human Physiology, University of Genova, Italy
    J Neurochem 84:253-65. 2003
    ....
  61. ncbi request reprint [Drugs of abuse, protein phosphatases, and ERK pathway]
    Emmanuel Valjent
    Med Sci (Paris) 21:453-4. 2005
  62. ncbi request reprint Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A
    Gilliane Maton
    Laboratoire de Biologie du Developpement, UMR CNRS 7622, Universite Pierre et Marie Curie, Boite 24, 4 place Jussieu, 75252 Paris, Cedex 5, France
    J Cell Sci 118:2485-94. 2005
    ..This strongly suggests that in Xenopus oocytes, Aurora-A activation is mainly controlled by the specific stimulation of kinases under the control of Cdc2 and not by downregulation of phosphatase...
  63. ncbi request reprint MafA transcription factor is phosphorylated by p38 MAP kinase
    Karine Sii-Felice
    UMR 146 CNRS Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay Cedex, France
    FEBS Lett 579:3547-54. 2005
    ..Furthermore, we show that p38 also phosphorylates MafB and c-Maf. Together, these findings suggest that the p38 MAP kinase pathway is a novel regulator of large Maf transcription factors...
  64. pmc PGY repeats and N-glycans govern the trafficking of paranodin and its selective association with contactin and neurofascin-155
    Carine Bonnon
    Neurobiologie des Interactions Cellulaires et Neurophysiopathologie, CNRS UMR 6184, Universite de la Mediterranee, Institut Jean Roche, 13916 Marseille Cedex 20, France
    Mol Biol Cell 18:229-41. 2007
    ..Thus, the unconventional processing of paranodin and contactin may determine the selective association of axo-glial complexes at paranodes...
  65. pmc DARPP-32 is a robust integrator of dopamine and glutamate signals
    Eric Fernandez
    EMBL EBI, Wellcome Trust Genome Campus, Hinxton, United Kingdom
    PLoS Comput Biol 2:e176. 2006
    ..Progressive inclusion of additional components should lead to a realistic model of signalling networks underlying the function of striatal neurons...