C Gicquel

Summary

Country: France

Publications

  1. ncbi Hormonal regulation of fetal growth
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Armand Trousseau, Paris, France
    Horm Res 65:28-33. 2006
  2. ncbi Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome
    Christine Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Inserm U515 et UPMC Paris 6, Hopital Armand Trousseau, AP HP, 26 Avenue Arnold Netter, 75012 Paris, France
    Nat Genet 37:1003-7. 2005
  3. ncbi Alterations of the 11p15 imprinted region and the IGFs system in a case of recurrent non-islet-cell tumour hypoglycaemia (NICTH)
    J Bertherat
    Clinique des Maladies Endocriniennes et Métaboliques CNRS UPR 1524, Hopital Cochin, Universite Rene Descartes, Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Armand Trousseau, Paris, France
    Clin Endocrinol (Oxf) 53:213-20. 2000
  4. ncbi Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith-Wiedemann syndrome
    V Gaston
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, AP HP, Paris, France
    Eur J Hum Genet 9:409-18. 2001
  5. ncbi Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, AP HP, 75012 Paris, France
    Cancer Res 61:6762-7. 2001
  6. ncbi Epigenetics, genomic imprinting and assisted reproductive technology
    Y Le Bouc
    Explorations Fonctionnelles Endocriniennes, Hopital d Enfants Armand Trousseau, AP HP, 75571 Paris, France
    Ann Endocrinol (Paris) 71:237-8. 2010
  7. ncbi Fibroblast growth factor-2 inhibits the maturation of pro-insulin-like growth factor-II (Pro-IGF-II) and the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in the human adrenocortical tumor cell line NCI-H295R
    N Boulle
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, Paris, France
    Endocrinology 141:3127-36. 2000
  8. ncbi Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors
    N Boulle
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, 26 Avenue Arnold Netter, AP HP and Unité INSERM U515, Hôpital Saint Antoine 75012 Paris, France
    Eur J Endocrinol 144:29-36. 2001
  9. ncbi Monoclonality of corticotroph macroadenomas in Cushing's disease
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, Paris, France
    J Clin Endocrinol Metab 75:472-5. 1992
  10. ncbi The epigenetic imprinting defect of patients with Beckwith-Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region
    S Rossignol
    Laboratoire d'Explorations Fonctionnelles Endocriniennes, , , Paris, France
    J Med Genet 43:902-7. 2006

Collaborators

Detail Information

Publications15

  1. ncbi Hormonal regulation of fetal growth
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Armand Trousseau, Paris, France
    Horm Res 65:28-33. 2006
    ....
  2. ncbi Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome
    Christine Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Inserm U515 et UPMC Paris 6, Hopital Armand Trousseau, AP HP, 26 Avenue Arnold Netter, 75012 Paris, France
    Nat Genet 37:1003-7. 2005
    ..These findings provide new insight into the pathogenesis of SRS and strongly suggest that the 11p15 imprinted region, in addition to those of 7p11.2-p13 and 7q31-qter, is involved in SRS...
  3. ncbi Alterations of the 11p15 imprinted region and the IGFs system in a case of recurrent non-islet-cell tumour hypoglycaemia (NICTH)
    J Bertherat
    Clinique des Maladies Endocriniennes et Métaboliques CNRS UPR 1524, Hopital Cochin, Universite Rene Descartes, Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Armand Trousseau, Paris, France
    Clin Endocrinol (Oxf) 53:213-20. 2000
    ..We report an extensive study of IGF-II and IGFBPs as well as chromosome 11p15 gene expression regulation in a case of a pleural fibrosarcoma in a 63-year-old patient presenting with NICTH...
  4. ncbi Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith-Wiedemann syndrome
    V Gaston
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, AP HP, Paris, France
    Eur J Hum Genet 9:409-18. 2001
    ..We also evaluated clinical and molecular features as prognostic factors for tumour and showed that mosaicism for 11p15 UPD and hypermethylation of the H19 gene in blood cells were associated with an increased risk of tumour...
  5. ncbi Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, AP HP, 75012 Paris, France
    Cancer Res 61:6762-7. 2001
    ..In patients who have undergone curative surgery, routine assessment of these tumor markers is a useful complement to histological scoring for predicting recurrence and guiding decisions for subsequent follow-up and management...
  6. ncbi Epigenetics, genomic imprinting and assisted reproductive technology
    Y Le Bouc
    Explorations Fonctionnelles Endocriniennes, Hopital d Enfants Armand Trousseau, AP HP, 75571 Paris, France
    Ann Endocrinol (Paris) 71:237-8. 2010
    ..3]). This suggests that unfaithful maintenance of DNA methylation marks following fertilization involves the dysregulation of a trans-acting regulatory factor that could be altered by ART...
  7. ncbi Fibroblast growth factor-2 inhibits the maturation of pro-insulin-like growth factor-II (Pro-IGF-II) and the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in the human adrenocortical tumor cell line NCI-H295R
    N Boulle
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, Paris, France
    Endocrinology 141:3127-36. 2000
    ..Moreover, this study shows a novel effect of FGF-2, by which this growth factor modulates the processing of pro-IGF-II...
  8. ncbi Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors
    N Boulle
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, 26 Avenue Arnold Netter, AP HP and Unité INSERM U515, Hôpital Saint Antoine 75012 Paris, France
    Eur J Endocrinol 144:29-36. 2001
    ..Circulating markers specific for adrenocortical carcinoma are needed and the aim of this study was to evaluate plasma IGFBP-2 as a marker for these malignant tumors...
  9. ncbi Monoclonality of corticotroph macroadenomas in Cushing's disease
    C Gicquel
    Laboratoire d Explorations Fonctionnelles Endocriniennes, Hopital Trousseau, Paris, France
    J Clin Endocrinol Metab 75:472-5. 1992
    ..Ours results show that a somatic modification plays an important role in the pathogenesis of corticotroph macroadenomas allowing monoclonal expansion of a genetically aberrant cell...
  10. ncbi The epigenetic imprinting defect of patients with Beckwith-Wiedemann syndrome born after assisted reproductive technology is not restricted to the 11p15 region
    S Rossignol
    Laboratoire d'Explorations Fonctionnelles Endocriniennes, , , Paris, France
    J Med Genet 43:902-7. 2006
    ..Moreover, the mosaic distribution of epimutations suggests that imprinting is lost after fertilisation owing to a failure to maintain methylation marks during pre-implantation development...
  11. ncbi Insights into the molecular biology of adrenocortical tumors
    L Groussin
    , Endocrinology Department, , Paris, France
    Exp Clin Endocrinol Diabetes 115:175-8. 2007
  12. ncbi Epigenetic abnormalities of the mannose-6-phosphate/IGF2 receptor gene are uncommon in human overgrowth syndromes
    C Gicquel
    J Med Genet 41:e4. 2004
  13. ncbi Sonographic findings in Beckwith-Wiedemann syndrome related to H19 hypermethylation
    C Le Caignec
    Service de Genetique Medicale, Centre Hospitalo Universitaire, Nantes, France
    Prenat Diagn 24:165-8. 2004
    ..The rest of the fetal anatomy and the amniotic fluid volume appeared normal. After termination of the pregnancy, molecular analysis confirmed the diagnosis of BWS by showing an isolated hypermethylation of the H19 gene...
  14. ncbi Mutation and methylation analysis of TP53 in adrenal carcinogenesis
    S Sidhu
    Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Eur J Surg Oncol 31:549-54. 2005
    ..To investigate the role of coding region mutation and promoter hypermethylation of TP53 in adrenocortical cancer formation...
  15. ncbi [Involvement of the IGF system in the pathogenesis of adrenocortical tumors]
    C Gicquel
    Laboratoire d'Explorations Fonctionnelles Endocriniennes, , 75012 Paris
    Ann Endocrinol (Paris) 62:189-92. 2001
    ..These markers of the malignant phenotype might markedly improve our diagnosis and prognosis abilities...