A M Ghoumari

Summary

Country: France

Publications

  1. pmc Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum
    A M Ghoumari
    Institut National de la Santé et de la Recherche Médicale U488, Batiment Gregory Pincus, 80 rue du General Leclerc, 94276 Kremlin Bicêtre, France
    Proc Natl Acad Sci U S A 100:7953-8. 2003
  2. ncbi request reprint Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum
    A M Ghoumari
    INSERM U488, Bicetre, France
    J Neurochem 86:848-59. 2003
  3. ncbi request reprint Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures
    A M Ghoumari
    INSERM U488, Batiment Gregory Pincus, 80 rue du General Leclerc, 94276 Bicêtre, France
    Neuroscience 135:47-58. 2005
  4. ncbi request reprint Neuroprotective effect of mifepristone involves neuron depolarization
    A M Ghoumari
    INSERM UMR788 and University Paris XI, Bicetre, France
    FASEB J 20:1377-86. 2006
  5. ncbi request reprint Bcl-2 protection of axotomized Purkinje cells in organotypic culture is age dependent and not associated with an enhancement of axonal regeneration
    A M Ghoumari
    INSERM U106, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
    Prog Brain Res 148:37-44. 2005

Detail Information

Publications5

  1. pmc Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum
    A M Ghoumari
    Institut National de la Santé et de la Recherche Médicale U488, Batiment Gregory Pincus, 80 rue du General Leclerc, 94276 Kremlin Bicêtre, France
    Proc Natl Acad Sci U S A 100:7953-8. 2003
    ..2-fold the survival of pcd/pcd Purkinje cells. Our results show that RU486 may act through a new mechanism, not yet elucidated, to protect Purkinje cells from death...
  2. ncbi request reprint Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum
    A M Ghoumari
    INSERM U488, Bicetre, France
    J Neurochem 86:848-59. 2003
    ....
  3. ncbi request reprint Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures
    A M Ghoumari
    INSERM U488, Batiment Gregory Pincus, 80 rue du General Leclerc, 94276 Bicêtre, France
    Neuroscience 135:47-58. 2005
    ..These results point to novel mechanisms by which progesterone may promote myelination in the CNS, specifically by stimulating the proliferation and maturation of oligodendrocyte precursors into myelinating oligodendrocytes...
  4. ncbi request reprint Neuroprotective effect of mifepristone involves neuron depolarization
    A M Ghoumari
    INSERM UMR788 and University Paris XI, Bicetre, France
    FASEB J 20:1377-86. 2006
    ..Mifepristone may be a useful lead compound in the development of novel therapeutic approaches for maintaining the resting potential of neurons at values favorable for their survival under neuropathological conditions...
  5. ncbi request reprint Bcl-2 protection of axotomized Purkinje cells in organotypic culture is age dependent and not associated with an enhancement of axonal regeneration
    A M Ghoumari
    INSERM U106, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
    Prog Brain Res 148:37-44. 2005