Romain K Gherardi

Summary

Country: France

Publications

  1. pmc Clinical heterogeneity of duchenne muscular dystrophy (DMD): definition of sub-phenotypes and predictive criteria by long-term follow-up
    Isabelle Desguerre
    Department of Neuropediatrics, Neuromuscular Disease Reference Center Garches Necker Mondor Hendaye, Necker Enfants Malades Hospital, Paris, France
    PLoS ONE 4:e4347. 2009
  2. ncbi request reprint Selective elevation of circulating CCL2/MCP1 levels in patients with longstanding post-vaccinal macrophagic myofasciitis and ASIA
    Josette Cadusseau
    Universite Paris Est, Faculté de Sciences et Technologie, Creteil, 94000, France
    Curr Med Chem 21:511-7. 2014
  3. doi request reprint Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis
    Romain K Gherardi
    CHU Henri Mondor, AP HP, centre de référence des maladies neuromusculaires Garches Necker_Mondor Hendaye, Service d Histologie, 94010 Creteil, France
    Presse Med 40:e209-18. 2011
  4. ncbi request reprint Endomysial fibrosis in Duchenne muscular dystrophy: a marker of poor outcome associated with macrophage alternative activation
    Isabelle Desguerre
    AP HP, Necker Enfants Malades Hospital, Neuropediatry Unit, Paris, France
    J Neuropathol Exp Neurol 68:762-73. 2009
  5. doi request reprint Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury
    Madly Brigitte
    INSERM U955, Groupe Hospitalier Henri Mondor Albert Chenevier, Assistance Publique Hopitaux de Paris, Universite Paris 12 Val de Marne, Creteil, France
    Arthritis Rheum 62:268-79. 2010
  6. pmc Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle
    Pierre François Lesault
    INSERM, U955, Creteil, France
    PLoS ONE 7:e46698. 2012
  7. ncbi request reprint Distinctive clinical features in arthro-myalgic patients with and without aluminum hydroxyde-induced macrophagic myofasciitis: an exploratory study
    Nilusha Ragunathan-Thangarajah
    INSERM U955 Equipe 10, Université Paris Est Créteil, Creteil, France
    J Inorg Biochem 128:262-6. 2013
  8. doi request reprint Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal
    Rana Abou-Khalil
    INSERM, U955, Creteil, France
    Cell Stem Cell 5:298-309. 2009
  9. pmc In vivo fusion of circulating fluorescent cells with dystrophin-deficient myofibers results in extensive sarcoplasmic fluorescence expression but limited dystrophin sarcolemmal expression
    Fabrice Chretien
    INSERM E0011, Cellular Interactions in the Neuromuscular System, Faculty of Medicine, Paris XII University, Creteil, France
    Am J Pathol 166:1741-8. 2005
  10. doi request reprint A new model of experimental fibrosis in hindlimb skeletal muscle of adult mdx mouse mimicking muscular dystrophy
    Isabelle Desguerre
    INSERM, U1016, Institut Cochin Département Génétique et Développement, Paris, France
    Muscle Nerve 45:803-14. 2012

Collaborators

Detail Information

Publications23

  1. pmc Clinical heterogeneity of duchenne muscular dystrophy (DMD): definition of sub-phenotypes and predictive criteria by long-term follow-up
    Isabelle Desguerre
    Department of Neuropediatrics, Neuromuscular Disease Reference Center Garches Necker Mondor Hendaye, Necker Enfants Malades Hospital, Paris, France
    PLoS ONE 4:e4347. 2009
    ..To explore clinical heterogeneity of Duchenne muscular dystrophy (DMD), viewed as a major obstacle to the interpretation of therapeutic trials..
  2. ncbi request reprint Selective elevation of circulating CCL2/MCP1 levels in patients with longstanding post-vaccinal macrophagic myofasciitis and ASIA
    Josette Cadusseau
    Universite Paris Est, Faculté de Sciences et Technologie, Creteil, 94000, France
    Curr Med Chem 21:511-7. 2014
    ..These results suggest that CCL2 may represent a biological marker relevant to the pathophysiology of MMF rather than a non specific inflammatory marker and that it should be checked in the other syndromes constitutive of ASIA. ..
  3. doi request reprint Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis
    Romain K Gherardi
    CHU Henri Mondor, AP HP, centre de référence des maladies neuromusculaires Garches Necker_Mondor Hendaye, Service d Histologie, 94010 Creteil, France
    Presse Med 40:e209-18. 2011
    ....
  4. ncbi request reprint Endomysial fibrosis in Duchenne muscular dystrophy: a marker of poor outcome associated with macrophage alternative activation
    Isabelle Desguerre
    AP HP, Necker Enfants Malades Hospital, Neuropediatry Unit, Paris, France
    J Neuropathol Exp Neurol 68:762-73. 2009
    ....
  5. doi request reprint Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury
    Madly Brigitte
    INSERM U955, Groupe Hospitalier Henri Mondor Albert Chenevier, Assistance Publique Hopitaux de Paris, Universite Paris 12 Val de Marne, Creteil, France
    Arthritis Rheum 62:268-79. 2010
    ..This study was undertaken to explore both the cell dynamics and functions of resident macrophages and dendritic cells (DCs) in damaged muscle, using a mouse model of notexin-induced myoinjury to study innate immune cell reactions...
  6. pmc Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle
    Pierre François Lesault
    INSERM, U955, Creteil, France
    PLoS ONE 7:e46698. 2012
    ....
  7. ncbi request reprint Distinctive clinical features in arthro-myalgic patients with and without aluminum hydroxyde-induced macrophagic myofasciitis: an exploratory study
    Nilusha Ragunathan-Thangarajah
    INSERM U955 Equipe 10, Université Paris Est Créteil, Creteil, France
    J Inorg Biochem 128:262-6. 2013
    ....
  8. doi request reprint Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal
    Rana Abou-Khalil
    INSERM, U955, Creteil, France
    Cell Stem Cell 5:298-309. 2009
    ..We propose that Ang1/Tie-2 signaling regulates mpc self-renewal by controlling the return to quiescence of a subset of satellite cells...
  9. pmc In vivo fusion of circulating fluorescent cells with dystrophin-deficient myofibers results in extensive sarcoplasmic fluorescence expression but limited dystrophin sarcolemmal expression
    Fabrice Chretien
    INSERM E0011, Cellular Interactions in the Neuromuscular System, Faculty of Medicine, Paris XII University, Creteil, France
    Am J Pathol 166:1741-8. 2005
    ....
  10. doi request reprint A new model of experimental fibrosis in hindlimb skeletal muscle of adult mdx mouse mimicking muscular dystrophy
    Isabelle Desguerre
    INSERM, U1016, Institut Cochin Département Génétique et Développement, Paris, France
    Muscle Nerve 45:803-14. 2012
    ..However, the dystrophin-deficient mdx mouse does not have fibrotic lesions in adult limb muscles. Here, we describe a model of chronic mechanical muscle injury that triggers chronic lesions in mdx hindlimb muscle...
  11. doi request reprint Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction
    Maryline Couette
    INSERM, Unite U955, Team 1, Creteil F 94010, France
    J Inorg Biochem 103:1571-8. 2009
    ..In conclusion, long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction, not solely due to chronic pain, fatigue and depression...
  12. doi request reprint Bone grafts cultured with bone marrow stromal cells for the repair of critical bone defects: an experimental study in mice
    Aline Dumas
    INSERM, U922, LHEA, Faculte de Medecine, 49045 Angers Cedex, France
    J Biomed Mater Res A 90:1218-29. 2009
    ..No GFP+ cell was noted after 8 weeks. However, pre-implantation culture of the biomaterial with allogenic BMSC greatly enhanced the bone regeneration...
  13. pmc Adult bone marrow-derived stem cells in muscle connective tissue and satellite cell niches
    Patrick A Dreyfus
    INSERM EMI 0011, Universite Paris XII, Creteil, France
    Am J Pathol 164:773-9. 2004
    ..We conclude that both muscle satellite cells and stem cell marker-expressing cells located in muscle connective tissue can derive from BM in adulthood...
  14. ncbi request reprint Skeletal muscle involvement in human immunodeficiency virus (HIV)-infected patients in the era of highly active antiretroviral therapy (HAART)
    François Jérome Authier
    Hopital Henri Mondor, Departement de Pathologie, Creteil F 94010, France
    Muscle Nerve 32:247-60. 2005
    ....
  15. pmc Muscle satellite cells and endothelial cells: close neighbors and privileged partners
    Christo Christov
    INSERM, Unite 841, IMRB, Team No 10, Creteil, F 94000, France
    Mol Biol Cell 18:1397-409. 2007
    ..Thus, SCs are largely juxtavascular and reciprocally interact with ECs during differentiation to support angio-myogenesis...
  16. pmc Slow CCL2-dependent translocation of biopersistent particles from muscle to brain
    Zakir Khan
    INSERM, U955, 8 rue du General Sarrail, Creteil, 94010, France
    BMC Med 11:99. 2013
    ....
  17. doi request reprint Whole microvascular unit deletions in dermatomyositis
    Cyril Gitiaux
    Neuropediatry Unit, AP HP, Necker Enfants Malades, Hospital, Paris, France
    Ann Rheum Dis 72:445-52. 2013
    ..The study is a reappraisal of the microvascular involvement in light of the microvascular organisation in normal human muscle...
  18. doi request reprint Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model
    Hua Liao
    INSERM U955, E10, Universite Paris Est, Creteil, France
    Arthritis Rheum 64:3441-51. 2012
    ..To investigate the influence of myoinjury on antigen presentation to T cells in draining lymph nodes (LNs)...
  19. pmc Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    Ludovic Arnold
    Institut National de la Sante et de la Recherche Medicale, Unite 841, Institut Mondor de Recherche Biomedicale, Cell Interactions in the Neuromuscular System Team, Universite Paris 12 Val de Marne, Creteil, France
    J Exp Med 204:1057-69. 2007
    ..In conclusion, injured skeletal muscle recruits MOs exhibiting inflammatory profiles that operate phagocytosis and rapidly convert to antiinflammatory MPs that stimulate myogenesis and fiber growth...
  20. doi request reprint Dual effects of exercise in dysferlinopathy
    Olivier Biondi
    Cellular Interactions in the Neuromuscular System Team, INSERM U955 E 10, Université Paris Est Créteil, Creteil, France
    Am J Pathol 182:2298-309. 2013
    ..Transposed to humans, our results may suggest that the past activity profile shapes the clinical phenotype of the myopathy and that patients with dysferlinopathy should likely benefit from concentric exercise-based physiotherapy...
  21. ncbi request reprint Aluminum inclusion macrophagic myofasciitis: a recently identified condition
    Romain K Gherardi
    Muscle and Nerve Group, Henri Mondor University Hospital, Creteil, France
    Immunol Allergy Clin North Am 23:699-712. 2003
    ....
  22. doi request reprint Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF)
    Elodie Passeri
    Paris Est Creteil University and Henri Mondor University Hospital APHP Reference Center for Neuromuscular Diseases Garches Necker Mondor Hendaye, Creteil, F 94010, France
    J Inorg Biochem 105:1457-63. 2011
    ..Long-term follow-up of a subset of patients with 3 or 4 consecutive neuropsychological evaluations confirmed the stability of MACD with time, despite marked fluctuations...
  23. pmc Satellite cells attract monocytes and use macrophages as a support to escape apoptosis and enhance muscle growth
    Bénédicte Chazaud
    Institut National de la Sante et de la Recherche Medicale, EMI 00 11, Faculte de Medecine, 8 rue du General Sarrail, 94000 Creteil, France
    J Cell Biol 163:1133-43. 2003
    ..We conclude that once activated, mpc, which are located close by capillaries, initiate monocyte recruitment and interplay with MP to amplify chemotaxis and enhance muscle growth...