Kamel Ghedira

Summary

Country: France

Publications

  1. doi request reprint A comparative evaluation of mutagenic, antimutagenic, radical scavenging and antibacterial activities of essential oils of Pituranthos chloranthus (Coss. et Dur.)
    Aicha Neffati
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03 Faculté de Pharmacie de Monastir, Monastir, Tunisie
    Drug Chem Toxicol 32:372-80. 2009
  2. pmc Pharmacological, antioxidant, genotoxic studies and modulation of rat splenocyte functions by Cyperus rotundus extracts
    Kilani Jaziri Soumaya
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculté de Médecine dentaire de Monastir, Universite de Monastir, Monastir, Tunisie
    BMC Complement Altern Med 13:28. 2013
  3. doi request reprint Antioxidant and antigenotoxic activities in Acacia salicina extracts and its protective role against DNA strand scission induced by hydroxyl radical
    Ines Bouhlel Chatti
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Tunisia
    Food Chem Toxicol 49:1753-8. 2011
  4. doi request reprint Antigenotoxic and antioxidant activities of isorhamnetin 3-O neohesperidoside from Acacia salicina
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Rue Avicenne, 5000 Monastir, Tunisie
    Drug Chem Toxicol 32:258-67. 2009
  5. ncbi request reprint Phytochemical, antibacterial, antiproliferative, and antioxidant potentials and DNA damage-protecting activity of Acacia salicina extracts
    Ines Bouhlel Chatti
    Unité de Pharmacognosie Biologie Moléculaire UR, Faculté de Pharmacie de Monastir, Tunisie
    J Med Food 12:675-83. 2009
  6. ncbi request reprint Antiproliferative, antioxidant, and antimutagenic activities of flavonoid-enriched extracts from (Tunisian) Rhamnus alaternus L.: combination with the phytochemical composition
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Monastir, Tunisie
    Drug Chem Toxicol 31:61-80. 2008
  7. doi request reprint Antioxidant activity and inhibition of aflatoxin B1-, nifuroxazide-, and sodium azide-induced mutagenicity by extracts from Rhamnus alaternus L
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Rue Avicenne, Monastir 5000, Tunisia
    Chem Biol Interact 174:1-10. 2008
  8. ncbi request reprint Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne 5000 Monastir, Tunisia
    Toxicol In Vitro 22:1264-72. 2008
  9. doi request reprint In vitro antioxidant and antigenotoxic potentials of myricetin-3-o-galactoside and myricetin-3-o-rhamnoside from Myrtus communis: modulation of expression of genes involved in cell defence system using cDNA microarray
    Nawel Hayder
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Toxicol In Vitro 22:567-81. 2008
  10. ncbi request reprint Mutagenic, antimutagenic and antioxidant potency of leaf extracts from Nitraria retusa
    Jihed Boubaker
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, Rue Avicenne, Monastir 5000, Tunisia
    Food Chem Toxicol 48:2283-90. 2010

Collaborators

  • Leila Chekir-Ghedira
  • Jihed Boubaker
  • Hedi Harizi
  • Isabelle Hininger-Favier
  • Fadwa Chaabane
  • Adel Nefzi
  • Jerome Ledauphin
  • Hedi Ben Mansour
  • Ines Bouhlel
  • Ines Skandrani
  • Mohamed Ben Sghaier
  • Wissem Bhouri
  • Soumaya Kilani
  • Ilef Limem
  • Aicha Neffati
  • Rebai Ben Ammar
  • Anne Marie Mariotte
  • Leila Chekir Ghedira
  • Marie Geneviève Dijoux-Franca
  • Mounira Krifa
  • Soumaya Kilani-Jaziri
  • Ines Bouhlel Chatti
  • Ilef Limem-Ben Amor
  • Francois Laporte
  • Kita Valenti
  • Amor Mahmoud
  • Afef Abdelwahed
  • Aicha Nefatti
  • Daniel Barillier
  • Kilani Jaziri Soumaya
  • Boubaker Jihed
  • Leila Ghedira-Chekir
  • Mohammed Ben Sghaier
  • Marie Genviève Dijoux Franca
  • Safa Derbal
  • Marie G Dijoux-Franca
  • Afef Dellai
  • Nawel Hayder
  • Aicha Naffeti
  • Régine Steiman
  • Malika Kadri
  • Mhalla Dhekra
  • Limem Ilef
  • Ghedira Kamel
  • Ghedira Zied
  • Chekir Ghedira Leila
  • Châbane Fadwa
  • Véronique Frachet
  • Franca Marie Genviève Dijoux
  • Mounira Kriffi
  • Xavier Ronot
  • Teheni Louhichi
  • Nouha Nasr
  • Rim Mensi
  • Anne M Mariotte
  • Mohamed B Sghaier
  • Weiqin Fang
  • Wissem Behouri
  • Meriem Bouchemi
  • Safa Derbel
  • Victor Nizet
  • Mary Hensler
  • Mohamed Ben-Sghaier
  • Didier Hennequin
  • Emmanuel Guedon
  • Hedi Ben Mansour
  • Nabil Chouchane
  • Mohamed Ghoul
  • Benoît Basset
  • Mohamed Ben Sghair
  • Mohamed Ben Sgaier
  • Marie Genviève Dijoux-Franca
  • Ridha Mosrati
  • Pascale Guiraud
  • Aicha Neffatti
  • A Neffati
  • Ribai Ben Ammar
  • Lobna Ezzi
  • Jemni Ben Chibani
  • Mohamed Hammami
  • Pascal Guiraud
  • Imed Chraief

Detail Information

Publications48

  1. doi request reprint A comparative evaluation of mutagenic, antimutagenic, radical scavenging and antibacterial activities of essential oils of Pituranthos chloranthus (Coss. et Dur.)
    Aicha Neffati
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03 Faculté de Pharmacie de Monastir, Monastir, Tunisie
    Drug Chem Toxicol 32:372-80. 2009
    ..The essential oils were tested for their antimicrobial properties against five different bacteria, and were found to be weakly active, with MIC and MBC values in the range 0.6-4 and 2.2-5 mg/mL, respectively...
  2. pmc Pharmacological, antioxidant, genotoxic studies and modulation of rat splenocyte functions by Cyperus rotundus extracts
    Kilani Jaziri Soumaya
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculté de Médecine dentaire de Monastir, Universite de Monastir, Monastir, Tunisie
    BMC Complement Altern Med 13:28. 2013
    ..rotundus. The antioxidant capacity and the modulation of splenocyte functions by these extracts were also investigated in mice. The phytochemical analysis was carried out using standard methods...
  3. doi request reprint Antioxidant and antigenotoxic activities in Acacia salicina extracts and its protective role against DNA strand scission induced by hydroxyl radical
    Ines Bouhlel Chatti
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Tunisia
    Food Chem Toxicol 49:1753-8. 2011
    ..The antioxidant and antimutagenecity activities exhibited by A. salicina depended on the chemical composition of the tested extracts...
  4. doi request reprint Antigenotoxic and antioxidant activities of isorhamnetin 3-O neohesperidoside from Acacia salicina
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Rue Avicenne, 5000 Monastir, Tunisie
    Drug Chem Toxicol 32:258-67. 2009
    ..Taken together, these observations provide evidence that the I3ON, isolated from the leaves of A. salicina, is able to protect cells against oxidative stress...
  5. ncbi request reprint Phytochemical, antibacterial, antiproliferative, and antioxidant potentials and DNA damage-protecting activity of Acacia salicina extracts
    Ines Bouhlel Chatti
    Unité de Pharmacognosie Biologie Moléculaire UR, Faculté de Pharmacie de Monastir, Tunisie
    J Med Food 12:675-83. 2009
    ..The antioxidant, antimicrobial, antigenotoxic, and cytotoxic activities exhibited by A. salicina depended on the chemical composition of the tested extracts...
  6. ncbi request reprint Antiproliferative, antioxidant, and antimutagenic activities of flavonoid-enriched extracts from (Tunisian) Rhamnus alaternus L.: combination with the phytochemical composition
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Monastir, Tunisie
    Drug Chem Toxicol 31:61-80. 2008
    ....
  7. doi request reprint Antioxidant activity and inhibition of aflatoxin B1-, nifuroxazide-, and sodium azide-induced mutagenicity by extracts from Rhamnus alaternus L
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Rue Avicenne, Monastir 5000, Tunisia
    Chem Biol Interact 174:1-10. 2008
    ..Our findings emphasize the potential of R. alaternus to prevent mutations and also its antioxidant effect...
  8. ncbi request reprint Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne 5000 Monastir, Tunisia
    Toxicol In Vitro 22:1264-72. 2008
    ..Taken together, these observations provide evidence that the chloroform and TOF extracts of A. salicina leaves contain bioactive compounds that are able to protect cells against the consequences of an oxidative stress...
  9. doi request reprint In vitro antioxidant and antigenotoxic potentials of myricetin-3-o-galactoside and myricetin-3-o-rhamnoside from Myrtus communis: modulation of expression of genes involved in cell defence system using cDNA microarray
    Nawel Hayder
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Toxicol In Vitro 22:567-81. 2008
    ....
  10. ncbi request reprint Mutagenic, antimutagenic and antioxidant potency of leaf extracts from Nitraria retusa
    Jihed Boubaker
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, Rue Avicenne, Monastir 5000, Tunisia
    Food Chem Toxicol 48:2283-90. 2010
    ..95mM trolox equivalent when tested by the ferric reducing/antioxidant method...
  11. ncbi request reprint Antimutagenic and antioxidant potentials of Teucrium ramosissimum essential oil
    Mohamed Ben Sghaier
    Department of Pharmacognosy, Faculty of Pharmacy, Rue Avicenne, Monastir 5000, Tunisia
    Chem Biodivers 7:1754-63. 2010
    ..A moderate free radical-scavenging activity was observed towards DPPH(.) and O2(.-). In contrast, T. ramosissimum essential oil showed no effect for all the tested concentrations in the X/XOD assay...
  12. doi request reprint Moricandia arvensis extracts protect against DNA damage, mutagenesis in bacteria system and scavenge the superoxide anion
    Ines Skandrani
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne, Monastir 5000, Tunisia
    Toxicol In Vitro 23:166-75. 2009
    ..TOF extract was the more effective one in inhibiting both xanthine oxidase activity and NBT reduction...
  13. doi request reprint Study of genotoxic, antigenotoxic and antioxidant activities of the digallic acid isolated from Pistacia lentiscus fruits
    Wissem Bhouri
    Unité de Pharmacognosie BiologieMoléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Toxicol In Vitro 24:509-15. 2010
    ..Our results revealed that digallic acid shows an important free radical scavenging activity towards the ABTS(+) radical (99%) and protection against lipid peroxidation (68%)...
  14. doi request reprint Leaf extracts from Moricandia arvensis promote antiproliferation of human cancer cells, induce apoptosis, and enhance antioxidant activity
    Ines Skandrani
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculty of Pharmacy, Monastir, Tunisia
    Drug Chem Toxicol 33:20-7. 2010
    ..arvensis extracts was evaluated by the ability of each extract to inhibit malondialdehyde formation. It was revealed that EA and TOF extracts are the most active in scavenging the hydroxyl radicals...
  15. ncbi request reprint Phlomis mauritanica extracts reduce the xanthine oxidase activity, scavenge the superoxide anions, and inhibit the aflatoxin B1-, sodium azide-, and 4-nitrophenyldiamine-induced mutagenicity in bacteria
    Ilef Limem
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, Monastir, Tunisia
    J Med Food 13:717-24. 2010
    ..mauritanica extracts to prevent mutations and oxidant effects. Furthermore, the results presented here could be an additional argument to support the use of this species as a medicinal and dietary plant...
  16. doi request reprint Cell protection induced by Acacia salicina extracts: inhibition of genotoxic damage and determination of its antioxidant capacity
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Monastir, Tunisia
    Drug Chem Toxicol 32:139-49. 2009
    ..Thus, A. salicina may serve as an ideal candidate for a cost- effective, readily exploitable natural phytochemical compound...
  17. ncbi request reprint Mutagenic, antimutagenic, cytotoxic, and apoptotic activities of extracts from Pituranthos tortuosus
    Afef Abdelwahed
    Unité de Pharmacognosie Biologie Moléculaire, Faculté de Pharmacie de Monastir, Monastir, Tunisie
    Drug Chem Toxicol 31:37-60. 2008
    ..The results revealed that all extracts showed a significant cytotoxic effect on these cell lines, and the effect was greater in the presence of human K562 chronic myelogenous leukemia cells, whereas they do not induce apoptosis...
  18. doi request reprint Evaluation of antioxidant and antigenotoxic activity of two flavonoids from Rhamnus alaternus L. (Rhamnaceae): kaempferol 3-O-β-isorhamninoside and rhamnocitrin 3-O-β-isorhamninoside
    Wissem Bhouri
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculté de Medecine Dentaire Monastir, Rue Avicenne, Monastir 5000, Tunisia
    Food Chem Toxicol 49:1167-73. 2011
    ..In this study, we have also evaluated correlation between antigenotoxic and antioxidant effects of K3O-ir and R3O-ir. The highest correlation was showed with R3O-ir (r=0.999)...
  19. pmc Polar extracts from (Tunisian) Acacia salicina Lindl. Study of the antimicrobial and antigenotoxic activities
    Jihed Boubaker
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, University of Monastir, Rue Avicenne, Monastir 5000, Tunisia
    BMC Complement Altern Med 12:37. 2012
    ..Methanolic, aqueous and Total Oligomer Flavonoids (TOF)-enriched extracts obtained from the leaves of Acacia salicina 'Lindl.' were investigated for antibacterial, antimutagenic and antioxidant activities...
  20. doi request reprint Screening of antimutagenicity via antioxidant activity in different extracts from the flowers of Phlomis crinita Cav. ssp mauritanica munby from the center of Tunisia
    Afef Dellai
    Unité de Recherche Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Monastir, Tunisie
    Drug Chem Toxicol 32:283-92. 2009
    ..crinita flowers are a significant source of compounds with antigenotoxic and antioxidant activity (most likely phenolic compounds) and thus may be useful candidates for chemoprevention studies...
  21. pmc Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562
    Jihed Boubaker
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, University of Monastir, Rue Avicenne, Monastir 5000, Tunisia
    BMC Complement Altern Med 12:135. 2012
    ....
  22. doi request reprint In vitro evaluation of antibacterial, antioxidant, cytotoxic and apoptotic activities of the tubers infusion and extracts of Cyperus rotundus
    Soumaya Kilani
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculty of Pharmacy of Monastir, 5000 Monastir, Tunisia
    Bioresour Technol 99:9004-8. 2008
    ..rotundus possess antibacterial and antioxidant properties and provoke DNA fragmentation, a sign of induction of apoptosis. These results were correlated with chemical composition of the tested extracts...
  23. pmc Antioxidant, genotoxic and antigenotoxic activities of daphne gnidium leaf extracts
    Fadwa Chaabane
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Monastir 5000, Tunisie
    BMC Complement Altern Med 12:153. 2012
    ..In fact, many plant extracts prepared from plants have been shown to exert biological activity in vitro and in vivo. The present study explored antioxidant and antigenotoxic effects of Daphne gnidium leaf extracts...
  24. doi request reprint Investigation of biological activity of polar extracts isolated from Phlomis crinita Cav ssp. mauritanica Munby
    Ilef Limem-Ben Amor
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, Monastir, Tunisia
    Drug Chem Toxicol 32:38-46. 2009
    ..This test demonstrates that 300 mg/kg of a P. crinita ssp. mauritanica lyophilized infusion was more effective than the reference compound, cimetidine...
  25. ncbi request reprint Transcriptional response of genes involved in cell defense system in human cells stressed by H2O2 and pre-treated with (Tunisian) Rhamnus alaternus extracts: combination with polyphenolic compounds and classic in vitro assays
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Rue Avicenne 5000 Monastir, Tunisie
    Chem Biol Interact 168:171-83. 2007
    ..R. alaternus extracts contain compounds with significant antioxidant and antigenotoxic activities. These compounds modulate gene expression as detected by using cDNA arrays...
  26. ncbi request reprint Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells
    Soumaya Kilani-Jaziri
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Rue Avicenne, Monastir, Tunisia
    Chem Biol Interact 181:85-94. 2009
    ..rotundus to inhibit the enzyme xanthine oxidase (XO), the lipid peroxidation and to exert apoptotic effect, may explain possible mechanisms by which C. rotundus exhibits its health benefits...
  27. doi request reprint In vitro and in vivo immunomodulatory and anti-ulcerogenic activities of Teucrium ramosissimum extracts
    Mohamed Ben Sghaier
    Unity of Pharmacognosy Molecular Biology, Faculty of Pharmacy, University of Monastir, Rue Avicenne, Monastir 5000, Tunisia
    J Immunotoxicol 8:288-97. 2011
    ..Nevertheless, ongoing/further studies are needed to clarify more precisely mechanisms underlying effects against ulcers and on lymphocyte and macrophage functionality, as well as the causative agents...
  28. pmc Antimutagenic and free radical scavenger effects of leaf extracts from Accacia salicina
    Jihed Boubaker
    Department of Cellular and Molecular Biology, Faculty of Dental Medicine, Rue Avicenne, Monastir, 5000, Tunisia
    Ann Clin Microbiol Antimicrob 10:37. 2011
    ....
  29. doi request reprint Anti-lipid peroxidation and induction of apoptosis in the erythroleukaemic cell line K562 by extracts from (Tunisian) Rhamnus alaternus L. (Rhamnaceae)
    Rebai Ben Ammar
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne, 5019 Monastir, Tunisie
    Nat Prod Res 25:1047-58. 2011
    ..Their IC₅₀ values were 196 and 273 µg mL⁻¹, respectively. These findings suggest that R. alaternus extracts exhibit potential antioxidant and proapoptotic properties...
  30. doi request reprint Phytochemistry and biological activities of Phlomis species
    Ilef Limem-Ben Amor
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, 5019 Monastir, Tunisia
    J Ethnopharmacol 125:183-202. 2009
    ..They are described according to antidiabetic, antinociceptive, antiulcerogenic, protection of the vascular system, anti-inflammatory, antiallergic, anticancer, antimicrobial and antioxidant properties...
  31. doi request reprint Flavonoids and sesquiterpenes from Tecurium ramosissimum promote antiproliferation of human cancer cells and enhance antioxidant activity: a structure-activity relationship study
    Mohamed Ben Sghaier
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Rue Avicenne, 5000 Monastir, Tunisia
    Environ Toxicol Pharmacol 32:336-48. 2011
    ..5, 1.39 and 0.71μM respectively. The cytotoxic activity revealed that the β-eudesmol inhibited significantly the proliferation of K562 cells (IC(50)=20μg/ml)...
  32. doi request reprint Comparative study of Cyperus rotundus essential oil by a modified GC/MS analysis method. Evaluation of its antioxidant, cytotoxic, and apoptotic effects
    Soumaya Kilani
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculty of Pharmacy, Monastir 5000, Tunisia
    Chem Biodivers 5:729-42. 2008
    ..This essential oil exhibited antioxidant, cytotoxic, and apoptotic properties...
  33. doi request reprint Flavonoids products from Nitraria retusa leaves promote lymphoblastoid cells apoptosis
    Boubaker Jihed
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, University of Monastir, Monastir, Tunisia
    Nutr Cancer 64:1095-102. 2012
    ..Our results indicate that the original ethyl acetate extract and the I3-O-Rob have a great antiproliferative effect on human lymphoblastoid cells (TK6), which may be due to their involvement in the apoptotic pathway...
  34. doi request reprint Anti-inflammatory and antiulcerogenic activities of leaf extracts and sesquiterpene from Teucrium ramosissimum (Lamiaceae)
    Mohamed Ben Sghaier
    Unity of Pharmacognosy Molecular Biology, Faculty of Pharmacy, Rue Avicenne, University of Monastir, Monastir, Tunisia
    Immunopharmacol Immunotoxicol 33:656-62. 2011
    ..Antiulcerogenic activity was examined on rat ethanol-induced ulcerogenic model. Compared with control (cimetidine), leaf extracts from T. ramosissimum exert different protective effects against ethanol-induced ulcerogenesis...
  35. ncbi request reprint Immunomodulatory and cellular anti-oxidant activities of an aqueous extract of Limoniastrum guyonianum gall
    Mounira Krifa
    Unité de Pharmacognosie Biologie Moléculaire, Faculté de Pharmacie de Monastir, Tunisia
    J Ethnopharmacol 146:243-9. 2013
    ..e., inflammation, autoimmune associated diseases, etc.). In this particular study, the immunomodulatory potential of gall aqueous extract from Limoniastrum guyonianum Boiss. (Zita) was assessed in vitro...
  36. doi request reprint Leaf extracts from Phlomis crinita Cav. subs. mauritanica Munby affect immune cell functions in vitro
    Ilef Limem
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculte de Medecine Dentaire, Monastir, Tunisie
    Immunopharmacol Immunotoxicol 33:309-14. 2011
    ..crinita subs. mauritanica Munby contain potent components such as flavonoids that potentially may be useful for modulating immune cell functions in physiological and pathological conditions...
  37. ncbi request reprint Influence of growth phase and geographic origin on the essential oil composition of Pituranthos chloranthus from Tunisia
    Aicha Neffati
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Facultd de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Nat Prod Commun 4:1585-94. 2009
    ..Limonene, camphene, geraniol and beta-damascenone were likely to be specific for the essential oils of this species collected from the different regions of Tunisia...
  38. doi request reprint Inhibition of proinflammatory macrophage responses and lymphocyte proliferation in vitro by ethyl acetate leaf extract from Daphne gnidium
    Hedi Harizi
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculte de Medecine Dentaire, Avenue Avicenne, 5019 Monastir, Tunisia
    Cell Immunol 267:94-101. 2011
    ..Collectively, these results demonstrate that D. gnidium EA leaf extract acts as an in vitro anti-inflammatory factor by inhibiting mice macrophage and lymphocyte activities...
  39. ncbi request reprint Chemical composition and antimicrobial activity of the essential oil of Teucrium ramosissimum (Lamiaceae)
    Mohamed Ben Sghaier
    Unity of Pharmacognosy Molecular Biology 99 UR 07 03, Faculty of Pharmacy, Rue Avicenne, Monastir, 5000, Tunisia
    Chem Biodivers 4:1480-6. 2007
    ..24-0.36 and 1.3-2.9 mg/ml, resp...
  40. doi request reprint Bioremediation of industrial pharmaceutical drugs
    Hedi Ben Mansour
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculte de Medecine Dentaire, Monastir, Tunisie
    Drug Chem Toxicol 35:235-40. 2012
    ..However, chromosome aberration, as well as LPO of PW, were significantly reduced after bioremediation. Thus, the use of this strain for testing on the industrial scale seems possible and advantageous...
  41. doi request reprint Flavones inhibit the proliferation of human tumor cancer cell lines by inducing apoptosis
    Soumaya Kilani-Jaziri
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Monastir, Tunisie
    Drug Chem Toxicol 35:1-10. 2012
    ..In conclusion, luteolin and apigenin exert cytotoxic effects in different cancer cell lines in which apoptosis plays an important role. Thus, flavones could be considered as potential chemotherapeutic agents...
  42. pmc Leaf extracts from Nitraria retusa promote cell population growth of human cancer cells by inducing apoptosis
    Jihed Boubaker
    Laboratory of Cellular and Molecular Biology, Faculty of Dental Medicine, University of Monastir, Rue Avicenne, Monastir, 5000, Tunisia
    Cancer Cell Int 11:37. 2011
    ..abstract:..
  43. doi request reprint Phytochemical potential of Daphne gnidium in inhibiting growth of melanoma cells and enhancing melanogenesis of B16-F0 melanoma
    Fadwa Chaabane
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculte de Pharmacie, Monastir, Tunisia
    Cell Biochem Funct 31:460-7. 2013
    ..Ethyl acetate extract has also the ability to enhance melanogenesis and tyrosinase activity of B16-F0 melanoma cells...
  44. ncbi request reprint Leaf and root extracts of Moricandia arvensis protect against DNA damage in human lymphoblast cell K562 and enhance antioxidant activity
    Ines Skandrani
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, 5000, Tunisia Laboratoire de Biologie Cellulaire et Moléculaire, Faculté de médicine dentaire, de Monastir, Rue Avicenne, 5000, Tunisia
    Environ Toxicol Pharmacol 30:61-7. 2010
    ..In addition, antioxidant potential study of root and leaf extracts using different antioxidant tests indicated that root extracts possess a potent antioxidant activity through namely their capacity to transfer electrons...
  45. ncbi request reprint Screening of antimutagenicity via antioxidant activity in different extracts from the leaves of Acacia salicina from the center of Tunisia
    Ines Bouhlel
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Environ Toxicol Pharmacol 23:56-63. 2007
    ..These extracts showed IC(50) value of 36, 73, 65, and 87μg/ml respectively. Taken together, our finding showed that A. salicina exhibits significant antioxidant and antigenotoxic activities...
  46. pmc Investigation of the apoptotic way induced by digallic acid in human lymphoblastoid TK6 cells
    Wissem Bhouri
    Laboratoire de Biologie Cellulaire et Moleculaire, Faculté de Medecine Dentaire Monastir, Rue Avicenne, Monastir, 5000 Tunisia
    Cancer Cell Int 12:26. 2012
    ..abstract:..
  47. ncbi request reprint Study of antimutagenic and antioxidant activities of gallic acid and 1,2,3,4,6-pentagalloylglucose from Pistacia lentiscus. Confirmation by microarray expression profiling
    Afef Abdelwahed
    Unité de Pharmacognosie Biologie Moléculaire 99 UR 07 03, Faculté de Pharmacie Médecine Dentaire de Monastir, Rue Avicenne, 5000 Monastir, Tunisia
    Chem Biol Interact 165:1-13. 2007
    ....
  48. pmc On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity
    Safa Derbal
    Laboratoire de Pharmacognosie, Faculte de Pharmacie, Rue Avicenne, 5000 Monastir, Tunisia
    Bioorg Med Chem Lett 20:5701-4. 2010
    ..In this work we also report the antibacterial activity of these analogs against several clinically-important drug-resistant Gram-positive and Gram-negative pathogens...