F Geissmann

Summary

Country: France

Publications

  1. pmc Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells
    F Geissmann
    Service d Anatomie Pathologique, Hopital Necker Enfants Malades, Paris, France
    J Exp Med 187:961-6. 1998
  2. ncbi request reprint TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells
    F Geissmann
    Unité de Recherche Associée 1461, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Unite 429, Paris, France
    J Immunol 162:4567-75. 1999
  3. ncbi request reprint Differentiation of Langerhans cells in Langerhans cell histiocytosis
    F Geissmann
    Institut Fédératif de Recherche Necker Enfants Malades Service d Anatomie Pathologique EA 219, Unité Mixte de Recherche 8603 CNRS Université Paris V, Paris, France
    Blood 97:1241-8. 2001
  4. ncbi request reprint Langerhans cell deficiency in reticular dysgenesis
    J F Emile
    Service d Anatomie Pathologique, Hopital Paul Brousse, and UPRES 1596, Universite Paris Sud, Villejuif, France
    Blood 96:58-62. 2000
  5. pmc Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin
    F Geissmann
    Service d Anatomie Pathologique, IFR Necker Enfants Malades, 75015 Paris, France
    J Exp Med 196:417-30. 2002
  6. ncbi request reprint Retinoic acid therapy in "degenerative-like" neuro-langerhans cell histiocytosis: a prospective pilot study
    Ahmed Idbaih
    Federation Neurologique Mazarin, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Pediatr Blood Cancer 43:55-8. 2004
  7. pmc Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
    P Aucouturier
    Institut National de la Santé et de la Recherche Médicale INSERM U25 and Centre National de la Recherche Scientifique U8603, Hopital Necker, Paris, France
    J Clin Invest 108:703-8. 2001

Collaborators

Detail Information

Publications7

  1. pmc Transforming growth factor beta1, in the presence of granulocyte/macrophage colony-stimulating factor and interleukin 4, induces differentiation of human peripheral blood monocytes into dendritic Langerhans cells
    F Geissmann
    Service d Anatomie Pathologique, Hopital Necker Enfants Malades, Paris, France
    J Exp Med 187:961-6. 1998
    ..e., the monocyte, in response to a TGF-beta1-rich microenvironment, as found in the skin and epithelia. Therefore, the monocyte may represent a circulating precursor critical to the immune response in vivo...
  2. ncbi request reprint TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells
    F Geissmann
    Unité de Recherche Associée 1461, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Unite 429, Paris, France
    J Immunol 162:4567-75. 1999
    ..We conclude that TGF-beta 1 appears to be responsible for both the acquisition of LC phenotype, cytokine production pattern, and prevention of noncognate maturation...
  3. ncbi request reprint Differentiation of Langerhans cells in Langerhans cell histiocytosis
    F Geissmann
    Institut Fédératif de Recherche Necker Enfants Malades Service d Anatomie Pathologique EA 219, Unité Mixte de Recherche 8603 CNRS Université Paris V, Paris, France
    Blood 97:1241-8. 2001
    ..Drugs that enhance the in vivo maturation of these immature DCs, or that induce their death, may be of therapeutic benefit...
  4. ncbi request reprint Langerhans cell deficiency in reticular dysgenesis
    J F Emile
    Service d Anatomie Pathologique, Hopital Paul Brousse, and UPRES 1596, Universite Paris Sud, Villejuif, France
    Blood 96:58-62. 2000
    ....
  5. pmc Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin
    F Geissmann
    Service d Anatomie Pathologique, IFR Necker Enfants Malades, 75015 Paris, France
    J Exp Med 196:417-30. 2002
    ..We suggest that during DL, inflammatory stimuli in the skin increase the migration of LCs to the lymph node but without associated maturation. Immature LCs might regulate immune responses during chronic inflammation...
  6. ncbi request reprint Retinoic acid therapy in "degenerative-like" neuro-langerhans cell histiocytosis: a prospective pilot study
    Ahmed Idbaih
    Federation Neurologique Mazarin, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Pediatr Blood Cancer 43:55-8. 2004
    ..Degenerative-like neuro-Langerhans cell histiocytosis (DN-LCH) is a rare complication of LCH marked by progressive cerebellar ataxia. No treatment has so far been shown to slow this progression...
  7. pmc Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
    P Aucouturier
    Institut National de la Santé et de la Recherche Médicale INSERM U25 and Centre National de la Recherche Scientifique U8603, Hopital Necker, Paris, France
    J Clin Invest 108:703-8. 2001
    ..These results suggest that CD11c(+) dendritic cells can propagate prions from the periphery to the CNS in the absence of any additional lymphoid element...