C Garrido

Summary

Country: France

Publications

  1. ncbi request reprint Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties
    Carmen Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, Université de Dijon, Dijon, France
    Cell Cycle 5:2592-601. 2006
  2. ncbi request reprint HSP27 inhibits cytochrome c-dependent activation of procaspase-9
    C Garrido
    INSERM U517, Groupe Biologie et Thérapie des Cancers JE 515, Faculty of Medicine and Pharmacy, 21033 Dijon, France
    FASEB J 13:2061-70. 1999
  3. ncbi request reprint Life's smile, death's grin: vital functions of apoptosis-executing proteins
    Carmen Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Curr Opin Cell Biol 16:639-46. 2004
  4. ncbi request reprint Quantifying Gp96/Grp94 complexes preparations for vaccines: a key step often inaccurate
    A Seignez
    Carmen Garrido, INSERM U866, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21079 Dijon, France
    Curr Med Chem 21:153-63. 2014
  5. doi request reprint The small heat shock proteins family: the long forgotten chaperones
    C Garrido
    Heat Shock Proteins and Cancer, Inserm UMR 866, Faculty of Medicine, Dijon, France
    Int J Biochem Cell Biol 44:1588-92. 2012
  6. ncbi request reprint HSP27 and HSP70: potentially oncogenic apoptosis inhibitors
    Carmen Garrido
    INSERM U517, Faculty of Medicine, 21033 Dijon, France
    Cell Cycle 2:579-84. 2003
  7. ncbi request reprint Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C
    Elise Schmitt
    Institut National de la Sante et de la Recherche Médicale U517, Faculty of Medicine, Dijon, France
    Cancer Res 64:2705-11. 2004
  8. ncbi request reprint A role of HSPs in apoptosis through "protein triage"?
    C Garrido
    INSERM U517, IFR100, Faculty of Medicine, 7 Boulevard Jeanne d Arc, 21000 Dijon, France
    Cell Death Differ 10:619-20. 2003
  9. ncbi request reprint Heat shock proteins: endogenous modulators of apoptotic cell death
    C Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, 7, boulevard Jeanne d Arc, Dijon, 21033, France
    Biochem Biophys Res Commun 286:433-42. 2001
  10. ncbi request reprint Hsp27 negatively regulates cell death by interacting with cytochrome c
    J M Bruey
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Nat Cell Biol 2:645-52. 2000

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties
    Carmen Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, Université de Dijon, Dijon, France
    Cell Cycle 5:2592-601. 2006
    ..The depletion or inhibition of HSP27 and HS70 frequently reduces the size of the tumors and even can cause their complete involution (for HSP70). Therefore, the inhibition of HSP70 and HSP27 has become a novel strategy of cancer therapy...
  2. ncbi request reprint HSP27 inhibits cytochrome c-dependent activation of procaspase-9
    C Garrido
    INSERM U517, Groupe Biologie et Thérapie des Cancers JE 515, Faculty of Medicine and Pharmacy, 21033 Dijon, France
    FASEB J 13:2061-70. 1999
    ..We conclude that HSP27 inhibits etoposide-induced apoptosis by preventing cytochrome c and dATP-triggered activity of caspase-9, downstream of cytochrome c release...
  3. ncbi request reprint Life's smile, death's grin: vital functions of apoptosis-executing proteins
    Carmen Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Curr Opin Cell Biol 16:639-46. 2004
    ..Moreover, therapeutic suppression of unwarranted cell death must be designed to target only the lethal (and not the vital) role of death effectors...
  4. ncbi request reprint Quantifying Gp96/Grp94 complexes preparations for vaccines: a key step often inaccurate
    A Seignez
    Carmen Garrido, INSERM U866, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21079 Dijon, France
    Curr Med Chem 21:153-63. 2014
    ..In this review, we discuss a hot topic: the use of the chaperone Gp96 for vaccination purposes in cancer, and also detail the current methods for quantifying Gp96-peptide preparations. ..
  5. doi request reprint The small heat shock proteins family: the long forgotten chaperones
    C Garrido
    Heat Shock Proteins and Cancer, Inserm UMR 866, Faculty of Medicine, Dijon, France
    Int J Biochem Cell Biol 44:1588-92. 2012
    ..In this mini-review we will just present a general introduction about the small heat shock proteins family. This article is part of a Directed Issue entitled: Small HSPs in physiology and pathology...
  6. ncbi request reprint HSP27 and HSP70: potentially oncogenic apoptosis inhibitors
    Carmen Garrido
    INSERM U517, Faculty of Medicine, 21033 Dijon, France
    Cell Cycle 2:579-84. 2003
    ..The down-regulation or selective inhibition of HSP70 might constitute a valuable strategy for the treatment of cancer...
  7. ncbi request reprint Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C
    Elise Schmitt
    Institut National de la Sante et de la Recherche Médicale U517, Faculty of Medicine, Dijon, France
    Cancer Res 64:2705-11. 2004
    ..These results delineate a novel strategy to sensitize colon cancer cells to chemotherapy and to increase their immunogenicity in immuno-competent hosts...
  8. ncbi request reprint A role of HSPs in apoptosis through "protein triage"?
    C Garrido
    INSERM U517, IFR100, Faculty of Medicine, 7 Boulevard Jeanne d Arc, 21000 Dijon, France
    Cell Death Differ 10:619-20. 2003
  9. ncbi request reprint Heat shock proteins: endogenous modulators of apoptotic cell death
    C Garrido
    Inserm U 517, Faculty of Medicine and Pharmacy, 7, boulevard Jeanne d Arc, Dijon, 21033, France
    Biochem Biophys Res Commun 286:433-42. 2001
    ..This review summarizes apoptosis-regulatory function of HSPs...
  10. ncbi request reprint Hsp27 negatively regulates cell death by interacting with cytochrome c
    J M Bruey
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Nat Cell Biol 2:645-52. 2000
    ..Thus, Hsp27 interferes specifically with the mitochondrial pathway of caspase-dependent cell death...
  11. ncbi request reprint Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis
    O Sordet
    Faculty of Medicine and Pharmacy, INSERM U517 and INSERM U498, IFR 100, 7 Boulevard Jeanne d'Arc, 21033 Dijon, France
    Blood 97:3931-40. 2001
    ..These data demonstrate that mitochondria-targeting agents bypass the resistance to classical anticancer drugs induced by TPA-mediated leukemic cell differentiation. (Blood. 2001;97:3931-3940)..
  12. doi request reprint Heat shock proteins: essential proteins for apoptosis regulation
    D Lanneau
    INSERM, UMR866, Dijon, France
    J Cell Mol Med 12:743-61. 2008
    ..Our purpose will be illustrated by emerging strategies in targeting these protective proteins to treat haematological malignancies...
  13. ncbi request reprint Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells
    S Gurbuxani
    INSERM 517, IFR 100, Faculty of Medicine, 7 Boulevard Jeanne d'Arc, 21033 Dijon, France
    Oncogene 20:7478-85. 2001
    ..Altogether, these results indicate that reduced level of HSP70 expression in PRO- colon cancer cells results in the generation of a specific immune response by promoting cell death in vivo...
  14. pmc Deleterious effect of serum proteins on the amphotericin B-induced potentiation of cisplatin in human colon cancer cells
    M Assem
    INSERM U252, , Dijon, France
    Br J Cancer 70:631-5. 1994
    ..The use of haemodilution to restore the positive AmB effect on platinum cellular accumulation cannot be warranted...
  15. pmc HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation
    Arnaud Parcellier
    INSERM U517, UFR Médecine et Pharmacie, 21033 Dijon, France
    Mol Cell Biol 23:5790-802. 2003
    ..This novel function of HSP27 would account for its antiapoptotic properties through the enhancement of NF-kappaB activity...
  16. ncbi request reprint Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes
    G Jego
    1 INSERM, UMR 866, Equipe Labellisée Ligue contre le Cancer, Dijon, France 2 Faculty of Medicine and Pharmacy, University of Burgundy, Dijon, France
    Leukemia 28:1676-86. 2014
    ..Taken together, HSF1 appears as a fine-tuning regulator of SPI1/PU.1 expression at the transcriptional and post-translational levels during macrophage differentiation of monocytes. ..
  17. doi request reprint Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity
    M Brunet Simioni
    INSERM U866, Dijon, France
    Oncogene 28:3332-44. 2009
    ..As we also show that HSP27 binds to the SUMO-E2-conjugating enzyme, Ubc9, our study raises the possibility that HSP27 may act as a SUMO-E3 ligase specific for SUMO-2/3...
  18. ncbi request reprint Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy
    E Schmitt
    Inserm U 517, 7 Boulevard Jeanne d Arc, Faculty of Medicine and Pharmacy, Dijon 21079, France, and Department of Hematology Oncology, University Hospital Regensburg, Germany
    J Leukoc Biol 81:15-27. 2007
    ..This review will focus on HSP27, HSP70, and HSP90. We will discuss the dual role of these HSPs, protective vs. immunogenic properties, making a special emphasis in their utility as targets in cancer therapy...
  19. ncbi request reprint Mechanisms of cytochrome c release from mitochondria
    C Garrido
    INSERM U517, Faculty of Medicine and Pharmacy, F 21033 Dijon, France
    Cell Death Differ 13:1423-33. 2006
    ..This review deals with the events involved in Cyt c release from mitochondria, with special attention to its regulation and final consequences...
  20. pmc Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level
    A Morizot
    INSERM, U866, Dijon, F 21079 France 2 Faculty of Medicine and Pharmacy, Universite de Bourgogne, Dijon, F 21079, France
    Cell Death Differ 18:700-11. 2011
    ..Our results clearly support a negative regulatory function for TRAIL-R4 in controlling TRAIL signaling, and unveil the ability of TRAIL-R4 to cooperate with c-FLIP to inhibit TRAIL-induced cell death...
  21. ncbi request reprint From nanotechnology to nanomedicine: applications to cancer research
    R Seigneuric
    Département Nanosciences, Laboratoire Interdisciplinaire Carnot de Bourgogne, CNRS UMR 5209, 9, Avenue Alain Savary, BP 47870, 21078 Dijon Cedex, France
    Curr Mol Med 10:640-52. 2010
    ..This translational review aims at integrating some recent advances from micro- and nano-technologies with high potential for improving daily oncology practice...
  22. ncbi request reprint Specific involvement of caspases in the differentiation of monocytes into macrophages
    Olivier Sordet
    Institut National de la Santé et de la Recherche Médicale INSERM U517, Institut Fédératif de Recherche IFR 100, Faculty of Medicine, Dijon, France
    Blood 100:4446-53. 2002
    ..Altogether, these results indicate that caspase activation specifically contributes to the differentiation of monocytes into macrophages, in the absence of cell death...
  23. pmc Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cells
    Dominique Thuringer
    INSERM U866, Faculty of Medicine, 7 Boulevard Jeanne d Arc, 21000 Dijon, France
    J Biol Chem 286:3418-28. 2011
    ..This mechanism could account for the deleterious effects of HSPs on high grade glioma when released into the tumor cell microenvironment...
  24. doi request reprint Bleomycin induces pleural and subpleural fibrosis in the presence of carbon particles
    N Decologne
    Institut National de la Santé et de la Recherche Médicale INSERM UMR 866, University of Burgundy, Dijon, France
    Eur Respir J 35:176-85. 2010
    ..It also suggests that carbon particles might be involved as a cofactor in the initiation and/or progression of (subpleural) pulmonary and pleural fibrosis. Mesothelial cells appear to be critical contributors to this fibrotic process...
  25. doi request reprint Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation
    C Didelot
    INSERM, UMR 866, Dijon, France
    Cell Death Differ 15:859-66. 2008
    ..Altogether, these results suggest that HSP90 beta prevents auto-ubiquitination and degradation of its client protein c-IAP1, whose depletion would be sufficient to inhibit cell differentiation...
  26. ncbi request reprint Atypical protein kinase C zeta as a target for chemosensitization of tumor cells
    Rodolphe Filomenko
    INSERM U517, EPHE, Ecole Pratique des Hautes Etudes, IFR, Institut Federatif de Recherche 100, Faculties of Medicine and Pharmacy, 21000 Dijon, France
    Cancer Res 62:1815-21. 2002
    ..These results indicate that PKCzeta isoform is a protective signals that is activated in tumor cells exposed to a cytotoxic agent. This inducible resistance factor thus appears an attractive target for chemosensitization of tumor cells...
  27. pmc Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells
    A de Thonel
    1 INSERM U866, Faculty of Medicine and Pharmacy, University of Burgundy, Dijon, France 2 Faculty of Medicine and Pharmacy, University of Burgundy, Dijon, France
    Cell Death Dis 5:e1016. 2014
    ..Thus, Par-4 seems a critical target of CK2 that could be exploited for the development of new anticancer drugs. ..
  28. ncbi request reprint Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways
    Arnaud Parcellier
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Biochem Biophys Res Commun 304:505-12. 2003
    ..Finally, HSPs could play a role in the proteasome-mediated degradation of selected proteins under stress conditions. Altogether, these properties could make HSPs appropriate targets for modulating cell death pathways...
  29. ncbi request reprint Small heat shock proteins HSP27 and alphaB-crystallin: cytoprotective and oncogenic functions
    Arnaud Parcellier
    Inserm U 517, IFR 100, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Antioxid Redox Signal 7:404-13. 2005
    ..Altogether, these properties suggest that these small heat shock proteins are appropriate targets for modulating cell death pathways...
  30. ncbi request reprint Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins
    Celine Didelot
    Inserm UMR 866, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21049 Dijon, France
    Curr Med Chem 14:2839-47. 2007
    ..This review will discuss this different and often paradoxical approaches in cancer therapy based on the dual role of Hsps, protective/tumorigenic versus immunogenic...
  31. ncbi request reprint Vital functions for lethal caspases
    Sophie Launay
    Inserm U 517, IFR100, Faculty of Medicine, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Oncogene 24:5137-48. 2005
    ..Deregulation of the pathways in which caspases exert these nonapoptotic functions is suspected to play a role in the pathophysiology of several human diseases...
  32. ncbi request reprint Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant
    Elise Schmitt
    Institut National de la Santé et de la Recherche Médicale U 517, Faculty of Medicine and Pharmacy, Dijon, France
    Cancer Res 63:8233-40. 2003
    ..Thus, its chemosensitizing effect was lost in cells in which inducible HSP70 genes had been deleted. These data delineate a novel strategy for the selective neutralization of HSP70...
  33. ncbi request reprint An atypical caspase-independent death pathway for an immunogenic cancer cell line
    Nicolas Larmonier
    INSERM U517, IFR 100, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21079 Dijon, France
    Oncogene 21:6091-100. 2002
    ..This unusual mode of cell death that associates necrotic and apoptotic features could provide optimal conditions for triggering a specific immune response...
  34. ncbi request reprint Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma
    Elise Schmitt
    Institut National de la Sante et de la Recherche Medicale, Faculty of Medicine, Dijon, France
    Cancer Res 66:4191-7. 2006
    ..ADD70 also shows an additive effect with HSP90 inhibition by 17-allylamino-17-demethoxygeldanamycin in vitro. Altogether, these data indicate the potential interest of targeting the HSP70 interaction with AIF for cancer therapy...
  35. doi request reprint HSP27 controls GATA-1 protein level during erythroid cell differentiation
    Aurelie de Thonel
    INSERM U866, Faculty of Medicine and Pharmacy, University of Burgundy, 7 Boulevard Jeanne d Arc, Dijon, France
    Blood 116:85-96. 2010
    ..We conclude that HSP27 plays a role in the fine-tuning of terminal erythroid differentiation through regulation of GATA-1 content and activity...
  36. doi request reprint Dual role of heat shock proteins as regulators of apoptosis and innate immunity
    Anne Laure Joly
    INSERM U866, Faculty of Medicine and Pharmacy, University of Dijon, Dijon, France
    J Innate Immun 2:238-47. 2010
    ..This review will focus on the roles of HSP70 and HSP90 in apoptosis and in innate immunity and how these functions are being exploited in cancer therapy...
  37. ncbi request reprint HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells
    Arnaud Parcellier
    INSERM, Dijon, France
    FASEB J 20:1179-81. 2006
    ..It facilitates the G1/S transition,which suggests that, in stressful conditions, HSP27might render quiescent cells competent to re-enter the cell cycle...
  38. pmc Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27
    David Lanneau
    Inserm UMR866, Faculty of Medicine, Dijon, France
    Prion 1:53-60. 2007
    ..This review will comment on the role of HSP90, HSP70 and HSP27 in apoptosis and cell differentiation. HSPs may determine de fate of the cells by orchestrating the decision of apoptosis versus differentiation...
  39. doi request reprint Heat shock proteins: cell protection through protein triage
    David Lanneau
    INSERM U866, University of Burgundy, Dijon, France
    ScientificWorldJournal 10:1543-52. 2010
    ..In this review, we will describe the different data that demonstrate a role for HSP90, HSP70, HSP27, and áB-crystallin in the partitioning of proteins to either one of these pathways, referred as protein triage...
  40. ncbi request reprint Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor
    Sandeep Gurbuxani
    Inserm U 517, Faculty of Medicine and Pharmacy, 7 Boulevard Jeanne d Arc, 21033 Dijon, France
    Oncogene 22:6669-78. 2003
    ..Altogether, our data demonstrate that AIF inhibition by HSP70 involves cytosolic retention of AIF. Moreover, it appears that endogenous HSP70 protein levels are sufficiently elevated to modulate the lethal action of AIF...
  41. pmc Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
    Fanny Chalmin
    INSERM U866, Dijon, France
    J Clin Invest 120:457-71. 2010
    ..Collectively, our findings show in both mice and humans that Hsp72 expressed at the surface of TDEs restrains tumor immune surveillance by promoting MDSC suppressive functions...
  42. ncbi request reprint CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
    Francois Ghiringhelli
    INSERM U517, Faculty of Medicine, Dijon, France
    Eur J Immunol 34:336-44. 2004
    ..These results demonstrate the role of CD4(+)CD25(+) regulatory T cells in tumor-induced immune tolerance and the interest of regulatory T cell depletion to sensitize established tumors to immunotherapy...
  43. ncbi request reprint A role for caspases in the differentiation of erythroid cells and macrophages
    Nathalie Droin
    INSERM, UMR 866, F 21079 Dijon, France
    Biochimie 90:416-22. 2008
    ....
  44. pmc HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
    Cyril Boyault
    Institut National de la Sante et de la Recherche Medicale INSERM, U823, Institut Albert Bonniot, Grenoble F 38706, France
    Genes Dev 21:2172-81. 2007
    ..HDAC6 therefore appears as a master regulator of the cell protective response to cytotoxic protein aggregate formation...
  45. pmc Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
    Noelia Casares
    Centre National de la Recherche Scientifique UMR8125, Institut Gustave Roussy, F 94805 Villejuif, France
    J Exp Med 202:1691-701. 2005
    ..These results delineate a procedure for the generation of cancer vaccines and the stimulation of anti-neoplastic immune responses in vivo...
  46. pmc Apoptosis regulation in tetraploid cancer cells
    Maria Castedo
    CNRS, UMR8125, Institut Gustave Roussy, Villejuif, France
    EMBO J 25:2584-95. 2006
    ..Tetraploid cells were also more resistant against UVC and gamma-irradiation. These data indicate the existence of p53-dependent alterations in apoptosis regulation in tetraploid cells...
  47. ncbi request reprint Rescue of early-stage myelodysplastic syndrome-deriving erythroid precursors by the ectopic expression of a dominant-negative form of FADD
    Yann Erick Claessens
    Departement d Hematologie, Institut Cochin, l Institut National de la Santé et de la Recherche Médicale U567, Centre National de la Recherche Scientifique Unité Mixtes de Recherche 8104, Universite Rene Descartes, Paris, France
    Blood 105:4035-42. 2005
    ....
  48. ncbi request reprint Phase I pharmacokinetic and pharmacodynamic study of weekly 1-hour and 24-hour infusion BMS-214662, a farnesyltransferase inhibitor, in patients with advanced solid tumors
    Josep Tabernero
    Medical Oncology Department, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain corrected
    J Clin Oncol 23:2521-33. 2005
    ....
  49. ncbi request reprint Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
    Jean Antoine Ribeil
    CNRS UMR 8147, Faculté de Médecine et Université René Descartes Paris V, Institut Fédérative Necker, 75270 Paris, France
    Nature 445:102-5. 2007
    ..These effects are abrogated by the transduction of a caspase-resistant GATA-1 mutant. Thus, in erythroid precursors undergoing terminal differentiation, Hsp70 prevents active caspase-3 from cleaving GATA-1 and inducing apoptosis...
  50. doi request reprint [Mitochondria HSP90: the target to inactivate in cancer therapy?]
    Celine Didelot
    Inserm UMR 866, Faculte de Medicine, 7, boulevard Jeanne d Arc, 21049 Dijon, France
    Med Sci (Paris) 24:363-4. 2008
  51. doi request reprint [Hsp 70, guardian angel of GATA-1 during erythroid differentiation]
    Julie Vandekerckhove
    CNRS UMR 8147 et Département d Hématologie, Faculté de Médecine et Université René Descartes Paris V, Hopital Necker, Paris Cedex 15, France
    Med Sci (Paris) 24:37-40. 2008
  52. ncbi request reprint Regulation of cytoplasmic stress granules by apoptosis-inducing factor
    Celine Cande
    CNRS UMR8125, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    J Cell Sci 117:4461-8. 2004
    ..Together, these data suggest that the oxidoreductase function of AIF is required for the maintenance of glutathione levels in stress conditions and that glutathione is a major regulator of SG...
  53. ncbi request reprint AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis
    Celine Cande
    CNRS UMR8125, Institut Gustave Roussy, Pavillon de Recherche 1, 39 rue Camille Desmoulins, F 94805 Villejuif, France
    Oncogene 23:1514-21. 2004
    ..In summary, AIF and CypA collaborate in chromatinolysis...