Research Topics
| B GarbaySummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
Myelin synthesis in the peripheral nervous systemB Garbay
Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen, Bordeaux 2, 146, rue Leo Saignat, Case 92, 33076, Bordeaux Cedex, France
Prog Neurobiol 61:267-304. 2000..During the same period, important data has been gathered concerning the synthesis and function of lipids in PNS myelin, although this field has received relatively little attention compared with that of their protein counterparts...- Trembler as a mouse model of CMT1A?B Garbay
Laboratoire de Biogenese Membranaire, UMR CNRS 5544, Universite Victor Segalen Bordeaux 2, France
Ann N Y Acad Sci 883:262-72. 1999..Therefore, the Trembler mutant is perhaps not an ideal model for this human neuropathy... - Gene expression of peroxisomal beta-oxidation enzymes in rat brainA Knoll
Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen Bordeaux 2, 146, Rue Léo Saignat Case 92, 33076, Bordeaux, France
Brain Res Mol Brain Res 74:217-20. 1999..Using the northern blot and RT-PCR techniques, a brain-specific expression is demonstrated for acyl-CoA oxidase 3II mRNA, thiolase-A and trans2,3enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase multifunctional enzyme type 2... - The homeotic protein dlk is expressed during peripheral nerve developmentP Costaglioli
Ecole Supérieure de Technologie des Biomolécules de Bordeaux, Universite Victor Segalen Bordeaux 2, France
FEBS Lett 509:413-6. 2001..These results suggest that dlk expression is required for Schwann cell acquisition of the myelinating phenotype... - High metabolism and subsequent elongation of 3-hydroxyeicosanoyl-CoA in very-long-chain fatty acid deficient PNS of Trembler miceF Sargueil
Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen Bordeaux 2, France
Neurosci Lett 273:29-32. 1999..C18-CoA condensing enzyme emerges as the only elongation step involved in the VLCFA deficit evidenced in Trembler PNS... - Hydroxyacyl-CoA dehydrase and trans-2,3-enoyl-CoA reductase activities are consistent with long-chain fatty acid accumulation during rat brain developmentA Knoll
Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen Bordeaux 2, France
Neurosci Lett 263:5-8. 1999..As a contribution to the quantitative estimation of the brain's ability to form its own VLCFA, it is shown that dehydrase and reductase activities are sufficient to allow the biosynthesis of all rat brain VLCFA at any age... - Expression of the exon 1A-containing PMP22 transcript is altered in the trembler mouseB Garbay
Laboratoire de Biogenese Membranaire, URA CNRS 1811, Universite de Bordeaux 2, France
Neurosci Lett 198:157-60. 1995.... - Regulation of oleoyl-CoA synthesis in the peripheral nervous system: demonstration of a link with myelin synthesisB Garbay
Laboratoire de Biogenese Membranaire, UMR CNRS 5544, Universite Victor Segalen Bordeaux 2, France
J Neurochem 71:1719-26. 1998..Similar experiments in a rat demyelination-remyelination model confirmed that SCD2 mRNA levels are regulated in the PNS in a similar manner to myelin-specific proteins... - Peroxisomal beta-oxidation enzyme gene expression in the developing mouse brainA Knoll
Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, Case 92, 33076, Bordeaux Cedex, France
Neurosci Lett 285:201-4. 2000.... - Expression of the ceramide galactosyltransferase gene during myelination of the mouse nervous system. Comparison with the genes encoding myelin basic proteins, choline kinase and CTP:phosphocholine cytidylyltransferaseB Garbay
Laboratoire de Biogenese Membranaire, URA CNRS 1811, IBGC du CNRS, Universite de Bordeaux II, France
Brain Res Dev Brain Res 83:119-24. 1994..Our results clearly indicate that the deficit in the accumulation of the galactosylceramides documented for this mutant is well correlated to a reduced CGT gene expression... - Acyl-CoA elongase expression during seed development in Brassica napusJ Puyaubert
, CNRS UMR 5544, , Bordeaux Cedex, France
Biochim Biophys Acta 1533:141-52. 2001..1 is quantitatively the major isoform expressed in seeds; (iv) that the Bn-FAE1 gene encodes a protein of 57 kDa responsible for the 3-ketoacyl-CoA synthase activity... - Cerebroside formation in the peripheral nervous system of normal and Trembler miceF Boiron-Sargueil
Laboratoire de Biogenèse Membranaire C N R S U R A 1811, Universite de Bordeaux II, France
Neurosci Lett 186:21-4. 1995..However, a higher rate of synthesis of short acyl chain-glucosyl ceramides is observed in the Trembler samples... - Over-expression of MBP and PLP messenger RNA in 8-day-old trembler brainL Bascles
Groupe d étude de l expression génétique, Institut de Biochimie Cellulaire du C N R S, Bordeaux, France
Neuroreport 5:1221-3. 1994..Whether a relationship exists between this observation and the onset of the clinical symptoms is still to be determined... - P0 protein in normal, trembler heterozygous/homozygous mice during active PNS myelinationB Garbay
Institut de Biochemie Cellulaire et Neurochimie du C N R S, Bordeaux, France
Neuroreport 3:594-6. 1992..This gene dosage effect should be taken into account when a molecular model of the Trembler mutation will be proposed... - Expression of the PMP-22 gene in Trembler mutant mice: comparison with the other myelin protein genesL Bascles
Institute de Biochimie cellulaire et Neurochimie, CNRS, Bordeaux, France
Dev Neurosci 14:336-41. 1992..This suggests that regulation of the expression of the PMP-22 gene is altered in the Trembler mutant...