Peggy Gandia

Summary

Country: France

Publications

  1. ncbi A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers
    Peggy Gandia
    Laboratoire Cinétique des Xénobiotiques, Faculte de Pharmacie, 35 chemin des Maraîches, 31062 Toulouse 4, France
    Int J Vitam Nutr Res 77:243-8. 2007
  2. ncbi Unexpected high levels of vorinostat when combined with vinorelbine in patients with advanced cancer
    Peggy Gandia
    EA4553, Institut Claudius Regaud and Universite de Toulouse, France
    Curr Clin Pharmacol 6:274-9. 2011
  3. doi Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC-MS/MS assay and ultrafiltration method
    Cécile Arellano
    EA4553, Laboratoire de Pharmacocinetique, Institut Claudius Regaud, 31052 Toulouse, France
    J Chromatogr B Analyt Technol Biomed Life Sci 907:94-100. 2012
  4. doi Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter
    Guylène Lafforgue
    Laboratoire Cinétique des Xénobiotiques, Faculte des sciences pharmaceutiques, 35 chemin des Maraichers, 31062 Toulouse Cedex 4, France
    Fundam Clin Pharmacol 22:189-201. 2008
  5. ncbi Is once-daily mesalazine equivalent to the currently used twice-daily regimen? A study performed in 30 healthy volunteers
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Institut Fédératif de Biologie, Hopital Purpan, TSA 70034, 330 avenue de Grande Bretagne, 31059 Toulouse Cedex 9, France
    J Clin Pharmacol 47:334-42. 2007
  6. ncbi Influence of simulated weightlessness on the oral pharmacokinetics of acetaminophen as a gastric emptying probe in man: a plasma and a saliva study
    Peggy Gandia
    Hôpital Rangueil Larrey, Toulouse, France
    J Clin Pharmacol 43:1235-43. 2003
  7. ncbi Influence of simulated weightlessness on the pharmacokinetics of acetaminophen administered by the oral route: a study in the rat
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Hôpital Rangueil Larrey, TSA 50032, 1 avenue Jean Poulhes, 31059 Toulouse Cedex 9, France
    Fundam Clin Pharmacol 18:57-64. 2004
  8. ncbi Influence of simulated weightlessness on the intramuscular and oral pharmacokinetics of promethazine in 12 human volunteers
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Hopital Purpan, Toulouse, France
    J Clin Pharmacol 46:1008-16. 2006

Collaborators

Detail Information

Publications8

  1. ncbi A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers
    Peggy Gandia
    Laboratoire Cinétique des Xénobiotiques, Faculte de Pharmacie, 35 chemin des Maraîches, 31062 Toulouse 4, France
    Int J Vitam Nutr Res 77:243-8. 2007
    ..Bis-glycinate administration was safe and well tolerated and bis-glycinate significantly increased the oral bioavailability of zinc (+43.4%) compared with the gluconate...
  2. ncbi Unexpected high levels of vorinostat when combined with vinorelbine in patients with advanced cancer
    Peggy Gandia
    EA4553, Institut Claudius Regaud and Universite de Toulouse, France
    Curr Clin Pharmacol 6:274-9. 2011
    ..Secondary aims were to determine (1) corresponding pharmacokinetics, (2) safety of this regimen, and (3) impact of UGT1A1 and 2B17 polymorphisms on vorinostat pharmacokinetics...
  3. doi Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC-MS/MS assay and ultrafiltration method
    Cécile Arellano
    EA4553, Laboratoire de Pharmacocinetique, Institut Claudius Regaud, 31052 Toulouse, France
    J Chromatogr B Analyt Technol Biomed Life Sci 907:94-100. 2012
    ..Our results clearly showed that the methodology and the features of devices used for ultrafiltration could totally compromise the determination of unbound concentrations of a drug...
  4. doi Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter
    Guylène Lafforgue
    Laboratoire Cinétique des Xénobiotiques, Faculte des sciences pharmaceutiques, 35 chemin des Maraichers, 31062 Toulouse Cedex 4, France
    Fundam Clin Pharmacol 22:189-201. 2008
    ..We suggest that the use of Caco-2 cells underestimates the role of the paracellular route in the absorption of hydrophilic drugs in vivo, and may exaggerate the role of influx transporters...
  5. ncbi Is once-daily mesalazine equivalent to the currently used twice-daily regimen? A study performed in 30 healthy volunteers
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Institut Fédératif de Biologie, Hopital Purpan, TSA 70034, 330 avenue de Grande Bretagne, 31059 Toulouse Cedex 9, France
    J Clin Pharmacol 47:334-42. 2007
    ..As it is desirable to offer patients a preparation with a less frequent administration to enhance compliance, this once-daily regimen may be an attractive dosing option...
  6. ncbi Influence of simulated weightlessness on the oral pharmacokinetics of acetaminophen as a gastric emptying probe in man: a plasma and a saliva study
    Peggy Gandia
    Hôpital Rangueil Larrey, Toulouse, France
    J Clin Pharmacol 43:1235-43. 2003
    ..The changes in Cmax and tmax indicated more rapid drug absorption, which could have been as a result of faster gastric emptying or an increased blood flow to the intestine...
  7. ncbi Influence of simulated weightlessness on the pharmacokinetics of acetaminophen administered by the oral route: a study in the rat
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Hôpital Rangueil Larrey, TSA 50032, 1 avenue Jean Poulhes, 31059 Toulouse Cedex 9, France
    Fundam Clin Pharmacol 18:57-64. 2004
    ..The increase in the Ka was probably because of an increased acceleration of the gastric emptying and/or to a decrease in the total peripheral resistance which increased intestinal blood flow...
  8. ncbi Influence of simulated weightlessness on the intramuscular and oral pharmacokinetics of promethazine in 12 human volunteers
    Peggy Gandia
    Laboratoire de Pharmacocinétique et Toxicologie Clinique, Hopital Purpan, Toulouse, France
    J Clin Pharmacol 46:1008-16. 2006
    ..The AUC was 3-fold higher when the drug was administered by the intramuscular route during both positions. Thus, intramuscular administration could be a good alternative to the oral route...