Virginie Gandemer

Summary

Country: France

Publications

  1. pmc Impact of age, leukocyte count and day 21-bone marrow response to chemotherapy on the long-term outcome of children with philadelphia chromosome-positive acute lymphoblastic leukemia in the pre-imatinib era: results of the FRALLE 93 study
    Virginie Gandemer
    Department of Pediatric Hematology, University Hospital of Rennes, Rennes, France
    BMC Cancer 9:14. 2009
  2. pmc Excellent prognosis of late relapses of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia: lessons from the FRALLE 93 protocol
    Virginie Gandemer
    Department of Pediatric Hematology Oncology, University Hospital of Rennes, France
    Haematologica 97:1743-50. 2012
  3. ncbi request reprint Multicenter randomized trial of chewing gum for preventing oral mucositis in children receiving chemotherapy
    Virginie Gandemer
    Department of Paediatrics, Teaching Hospitals 35203 Rennes Cedex, France
    J Pediatr Hematol Oncol 29:86-94. 2007
  4. pmc Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia
    Virginie Gandemer
    CNRS UMR 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Faculte de Medecine, IFR140 GFAS, 2 Av du Pr Leon Bernard, CS 34317, Rennes Cedex, France
    BMC Genomics 8:385. 2007
  5. doi request reprint Influence of previous antimicrobial therapy on oral carriage of beta-lactamase producing Capnocytophaga isolates
    Anne Jolivet-Gougeon
    Equipe de Microbiologie, UPRES EA 1254, Universite de Rennes, Rennes, France
    Acta Paediatr 97:964-7. 2008
  6. doi request reprint CD9 expression can be used to predict childhood TEL/AML1-positive acute lymphoblastic leukemia: proposal for an accelerated diagnostic flowchart
    Virginie Gandemer
    Centre National de Recherche Scientifique, Unité Mixte de Recherche 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Rennes Cedex, France
    Leuk Res 34:430-7. 2010
  7. ncbi request reprint Late ovarian relapse of TEL/AML1 positive ALL confirming that TEL deletion is a secondary event in leukemogenesis
    Beatrice Ly-Sunnaram
    Laboratoire d ématologie et d mmunologie CHU Université de Rennes1, avenue du professeur Leon Bernard, Rennes, France
    Leuk Res 29:1089-94. 2005
  8. ncbi request reprint Central neurotoxicity of cyclosporine in two children with nephrotic syndrome
    Sophie Taque
    Departement de medecine de l Enfant et de l Adolescent, CHU Rennes, Hopital Sud, 16 Boulevard de Bulgarie, 35056 Rennes, France
    Pediatr Nephrol 19:276-80. 2004
  9. ncbi request reprint Clinical value of pre-transplant minimal residual disease in childhood lymphoblastic leukaemia: the results of the French minimal residual disease-guided protocol
    Virginie Gandemer
    Department of Paediatric Haematology Oncology, University Hospital of Rennes, Rennes, France
    Br J Haematol 165:392-401. 2014
  10. ncbi request reprint Hearing loss during osteosarcoma chemotherapy: when acute ifosfamide toxicity revealed unnoticed methotrexate encephalopathy
    Guillaume Robert
    Departments of Pediatric Oncology Radiology, CHU Rennes CNRS IGDR UMR 6290, Institut Génétique et Développement de Rennes Université Rennes 1, UEB, IFR 140, Medical University, Rennes, France
    J Pediatr Hematol Oncol 36:e100-2. 2014

Collaborators

Detail Information

Publications21

  1. pmc Impact of age, leukocyte count and day 21-bone marrow response to chemotherapy on the long-term outcome of children with philadelphia chromosome-positive acute lymphoblastic leukemia in the pre-imatinib era: results of the FRALLE 93 study
    Virginie Gandemer
    Department of Pediatric Hematology, University Hospital of Rennes, Rennes, France
    BMC Cancer 9:14. 2009
    ..Here we report the long-term results of the FRALLE 93 study conducted in the era before the use of tyrosine kinase inhibitors...
  2. pmc Excellent prognosis of late relapses of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia: lessons from the FRALLE 93 protocol
    Virginie Gandemer
    Department of Pediatric Hematology Oncology, University Hospital of Rennes, France
    Haematologica 97:1743-50. 2012
    ..We performed a long-term, follow-up retrospective study to address the outcome of patients with ETV6/RUNX1-positive leukemia relapses...
  3. ncbi request reprint Multicenter randomized trial of chewing gum for preventing oral mucositis in children receiving chemotherapy
    Virginie Gandemer
    Department of Paediatrics, Teaching Hospitals 35203 Rennes Cedex, France
    J Pediatr Hematol Oncol 29:86-94. 2007
    ..72%, P=0.03). In the multivariate analysis, the risk of oral mucositis was related only to the type of chemotherapy regimen, suggesting that further strategies for preventing oral mucositis could be mainly based on these criteria...
  4. pmc Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia
    Virginie Gandemer
    CNRS UMR 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Faculte de Medecine, IFR140 GFAS, 2 Av du Pr Leon Bernard, CS 34317, Rennes Cedex, France
    BMC Genomics 8:385. 2007
    ..We report an analysis of gene expression in 60 children with B-lineage ALL using Agilent whole genome oligo-chips (44K-G4112A) and/or real time RT-PCR...
  5. doi request reprint Influence of previous antimicrobial therapy on oral carriage of beta-lactamase producing Capnocytophaga isolates
    Anne Jolivet-Gougeon
    Equipe de Microbiologie, UPRES EA 1254, Universite de Rennes, Rennes, France
    Acta Paediatr 97:964-7. 2008
    ..The examined parameters included clinical observation of oropharyngeal mucosa, type of malignant disease and intake of chemotherapy and antimicrobial treatment...
  6. doi request reprint CD9 expression can be used to predict childhood TEL/AML1-positive acute lymphoblastic leukemia: proposal for an accelerated diagnostic flowchart
    Virginie Gandemer
    Centre National de Recherche Scientifique, Unité Mixte de Recherche 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Rennes Cedex, France
    Leuk Res 34:430-7. 2010
    ..Finally, we propose a faster procedure for optimizing the diagnosis of childhood BCP-ALL subgroups...
  7. ncbi request reprint Late ovarian relapse of TEL/AML1 positive ALL confirming that TEL deletion is a secondary event in leukemogenesis
    Beatrice Ly-Sunnaram
    Laboratoire d ématologie et d mmunologie CHU Université de Rennes1, avenue du professeur Leon Bernard, Rennes, France
    Leuk Res 29:1089-94. 2005
    ..To our knowledge, it is the first complete description of extramedullary ALL relapse combining all methodologies...
  8. ncbi request reprint Central neurotoxicity of cyclosporine in two children with nephrotic syndrome
    Sophie Taque
    Departement de medecine de l Enfant et de l Adolescent, CHU Rennes, Hopital Sud, 16 Boulevard de Bulgarie, 35056 Rennes, France
    Pediatr Nephrol 19:276-80. 2004
    ..We present two patients with central neurotoxicity both of whom have elevated cholesterol levels...
  9. ncbi request reprint Clinical value of pre-transplant minimal residual disease in childhood lymphoblastic leukaemia: the results of the French minimal residual disease-guided protocol
    Virginie Gandemer
    Department of Paediatric Haematology Oncology, University Hospital of Rennes, Rennes, France
    Br J Haematol 165:392-401. 2014
    ..Thus, pre-transplant MRD is still a major predictor of outcome for ALL. The MRD-guided strategy resulted in survival for 72·3% of patients with MRD<10(-3) and 40·4% of those with MRD ≥10(-3)...
  10. ncbi request reprint Hearing loss during osteosarcoma chemotherapy: when acute ifosfamide toxicity revealed unnoticed methotrexate encephalopathy
    Guillaume Robert
    Departments of Pediatric Oncology Radiology, CHU Rennes CNRS IGDR UMR 6290, Institut Génétique et Développement de Rennes Université Rennes 1, UEB, IFR 140, Medical University, Rennes, France
    J Pediatr Hematol Oncol 36:e100-2. 2014
    ..This is the second reported case of acute deafness, possibly associated with ifosfamide, whereas MRI data revealed unnoticed chronic methotrexate toxicity. Systematic MRI screening and hearing evaluation may be useful in such cases. ..
  11. pmc Prevalence of oropharyngeal beta-lactamase-producing Capnocytophaga spp. in pediatric oncology patients over a ten-year period
    Anne Jolivet-Gougeon
    Equipe de Microbiologie, UPRES EA 1254, Faculte des Sciences Pharmaceutiques et Biologiques, Universite de Rennes 1, 2 Avenue du Professeur Leon Bernard, 35043 Rennes, France
    BMC Infect Dis 5:32. 2005
    ....
  12. ncbi request reprint Particular cutaneous side effects with etoposide-containing courses: is VP16 or etoposide phosphate responsible?
    Katel Marigny
    Department of Pharmacy, CHU Hopital Sud, bd de Bulgarie, 35000, Rennes, France
    Cancer Chemother Pharmacol 55:244-50. 2005
    ....
  13. doi request reprint School performance of childhood cancer survivors: mind the teenagers!
    Jacinthe Bonneau
    Department of Pediatric Hematology, University Hospital, Rennes, France
    J Pediatr 158:135-41. 2011
    ..To assess school performance in an unselected group of childhood cancer survivors and study risk factors for impairment...
  14. ncbi request reprint Prognostic signature of ALL blasts at diagnosis: what can we really find?
    Virginie Gandemer
    Leuk Res 31:1317-9. 2007
  15. ncbi request reprint Economic evaluation of recombinant human granulocyte colony-stimulating factor in very high-risk childhood acute lymphoblastic leukemia
    Jean Delorme
    Department of Pharmacy, Research Unit INSERM No 379, France
    J Pediatr Hematol Oncol 25:441-7. 2003
    ..The aim of the current study was to perform an economic evaluation in the same cohort...
  16. ncbi request reprint Outcome in children with relapsed acute myeloid leukemia after initial treatment with the French Leucemie Aique Myeloide Enfant (LAME) 89/91 protocol of the French Society of Pediatric Hematology and Immunology
    Nathalie Aladjidi
    Unité d Onco Hématologie, Departement de Pediatrie, Hopital des Enfants, Groupe Hospitalier Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux, France
    J Clin Oncol 21:4377-85. 2003
    ..The goals of this retrospective study were to determine whether these children could be treated successfully with a salvage regimen and to establish the optimal therapeutic strategy...
  17. ncbi request reprint High-dose chemotherapy followed by locoregional irradiation improves the outcome of patients with international neuroblastoma staging system Stage II and III neuroblastoma with MYCN amplification
    Anne Laprie
    Département d Hémato Oncologie, Hopital des Enfants, Toulouse, France
    Cancer 101:1081-9. 2004
    ..The objective of this study was to determine whether systemic and regional, intensified treatment can improve the outcome of children who present with a localized neuroblastoma (NB) with MYCN amplification (MNA)...
  18. doi request reprint Prognostic factors for leukemic induction failure in children with acute lymphoblastic leukemia and outcome after salvage therapy: the FRALLE 93 study
    Caroline Oudot
    Service d hématologie et oncologie pédiatrique, Hopital Mere Enfant, Limoges, France
    J Clin Oncol 26:1496-503. 2008
    ..To identify prognostic factors and to evaluate the outcome of children with acute lymphoblastic leukemia (ALL) failure after induction therapy...
  19. pmc Familial history of cancer and childhood acute leukemia: a French population-based case-control study
    Mahaut Ripert
    INSERM, U754, IFR69, Villejuif, France
    Eur J Cancer Prev 16:466-70. 2007
    ..7 [1.3-86], respectively). This study supports the hypothesis that a familial history of cancer may play a role in the etiology of childhood acute leukemia. It also evidences some specific associations that require further investigation...
  20. ncbi request reprint Results of a phase II trial testing interferon-alpha 2b and cytarabine in children and adolescents with chronic myelogenous leukemia
    Frederic Millot
    Oncology Hematology, University Hospital, Poitiers, France
    Pediatr Blood Cancer 47:555-9. 2006
    ....
  21. ncbi request reprint Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. Leucámie Aiqüe Myéloïde Enfant
    Yves Perel
    Unité d Onco Hématologie, Departement de Pediatrie, Hopital des Enfants, Groupe Hospitalier Pellegrin, Centres Hospitalo Universitaires de Bordeaux, France
    J Clin Oncol 20:2774-82. 2002
    ..To determine whether the use of maintenance therapy (MT) delivered after intensive induction and consolidation therapy confers any advantage in childhood acute myeloid leukemia (AML)...