Research Topics
Species | Virginie GandemerSummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
Impact of age, leukocyte count and day 21-bone marrow response to chemotherapy on the long-term outcome of children with philadelphia chromosome-positive acute lymphoblastic leukemia in the pre-imatinib era: results of the FRALLE 93 studyVirginie Gandemer
Department of Pediatric Hematology, University Hospital of Rennes, Rennes, France
BMC Cancer 9:14. 2009..Here we report the long-term results of the FRALLE 93 study conducted in the era before the use of tyrosine kinase inhibitors...
Excellent prognosis of late relapses of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia: lessons from the FRALLE 93 protocolVirginie Gandemer
Department of Pediatric Hematology Oncology, University Hospital of Rennes, France
Haematologica 97:1743-50. 2012..We performed a long-term, follow-up retrospective study to address the outcome of patients with ETV6/RUNX1-positive leukemia relapses...
Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemiaVirginie Gandemer
CNRS UMR 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Faculte de Medecine, IFR140 GFAS, 2 Av du Pr Leon Bernard, CS 34317, Rennes Cedex, France
BMC Genomics 8:385. 2007..We report an analysis of gene expression in 60 children with B-lineage ALL using Agilent whole genome oligo-chips (44K-G4112A) and/or real time RT-PCR...
Multicenter randomized trial of chewing gum for preventing oral mucositis in children receiving chemotherapyVirginie Gandemer
Department of Paediatrics, Teaching Hospitals 35203 Rennes Cedex, France
J Pediatr Hematol Oncol 29:86-94. 2007..72%, P=0.03). In the multivariate analysis, the risk of oral mucositis was related only to the type of chemotherapy regimen, suggesting that further strategies for preventing oral mucositis could be mainly based on these criteria...
Influence of previous antimicrobial therapy on oral carriage of beta-lactamase producing Capnocytophaga isolatesAnne Jolivet-Gougeon
Equipe de Microbiologie, UPRES EA 1254, Universite de Rennes, Rennes, France
Acta Paediatr 97:964-7. 2008..The examined parameters included clinical observation of oropharyngeal mucosa, type of malignant disease and intake of chemotherapy and antimicrobial treatment...
CD9 expression can be used to predict childhood TEL/AML1-positive acute lymphoblastic leukemia: proposal for an accelerated diagnostic flowchartVirginie Gandemer
Centre National de Recherche Scientifique, Unité Mixte de Recherche 6061 Laboratoire de Génétique et Développement, Equipe Régulation Transcriptionnelle et Oncogenèse, Universite de Rennes 1, Rennes Cedex, France
Leuk Res 34:430-7. 2010..Finally, we propose a faster procedure for optimizing the diagnosis of childhood BCP-ALL subgroups...
Late ovarian relapse of TEL/AML1 positive ALL confirming that TEL deletion is a secondary event in leukemogenesisBeatrice Ly-Sunnaram
, , Rennes, France
Leuk Res 29:1089-94. 2005..To our knowledge, it is the first complete description of extramedullary ALL relapse combining all methodologies...
Central neurotoxicity of cyclosporine in two children with nephrotic syndromeSophie Taque
Departement de medecine de l Enfant et de l Adolescent, CHU Rennes, Hopital Sud, 16 Boulevard de Bulgarie, 35056 Rennes, France
Pediatr Nephrol 19:276-80. 2004..We present two patients with central neurotoxicity both of whom have elevated cholesterol levels...
Prevalence of oropharyngeal beta-lactamase-producing Capnocytophaga spp. in pediatric oncology patients over a ten-year periodAnne Jolivet-Gougeon
Equipe de Microbiologie, UPRES EA 1254, Faculte des Sciences Pharmaceutiques et Biologiques, Universite de Rennes 1, 2 Avenue du Professeur Leon Bernard, 35043 Rennes, France
BMC Infect Dis 5:32. 2005....
School performance of childhood cancer survivors: mind the teenagers!Jacinthe Bonneau
Department of Pediatric Hematology, University Hospital, Rennes, France
J Pediatr 158:135-41. 2011..To assess school performance in an unselected group of childhood cancer survivors and study risk factors for impairment...
Particular cutaneous side effects with etoposide-containing courses: is VP16 or etoposide phosphate responsible?Katel Marigny
Department of Pharmacy, CHU Hopital Sud, bd de Bulgarie, 35000, Rennes, France
Cancer Chemother Pharmacol 55:244-50. 2005....
Prognostic signature of ALL blasts at diagnosis: what can we really find?Virginie Gandemer
Leuk Res 31:1317-9. 2007
Familial history of cancer and childhood acute leukemia: a French population-based case-control studyMahaut Ripert
INSERM, U754, IFR69, Villejuif, France
Eur J Cancer Prev 16:466-70. 2007..7 [1.3-86], respectively). This study supports the hypothesis that a familial history of cancer may play a role in the etiology of childhood acute leukemia. It also evidences some specific associations that require further investigation...
Prognostic factors for leukemic induction failure in children with acute lymphoblastic leukemia and outcome after salvage therapy: the FRALLE 93 studyCaroline Oudot
Service d hématologie et oncologie pédiatrique, Hopital Mere Enfant, Limoges, France
J Clin Oncol 26:1496-503. 2008..To identify prognostic factors and to evaluate the outcome of children with acute lymphoblastic leukemia (ALL) failure after induction therapy...
Results of a phase II trial testing interferon-alpha 2b and cytarabine in children and adolescents with chronic myelogenous leukemiaFrederic Millot
Oncology Hematology, University Hospital, Poitiers, France
Pediatr Blood Cancer 47:555-9. 2006....
High-dose chemotherapy followed by locoregional irradiation improves the outcome of patients with international neuroblastoma staging system Stage II and III neuroblastoma with MYCN amplificationAnne Laprie
Département d Hémato Oncologie, Hopital des Enfants, Toulouse, France
Cancer 101:1081-9. 2004..The objective of this study was to determine whether systemic and regional, intensified treatment can improve the outcome of children who present with a localized neuroblastoma (NB) with MYCN amplification (MNA)...
Outcome in children with relapsed acute myeloid leukemia after initial treatment with the French Leucemie Aique Myeloide Enfant (LAME) 89/91 protocol of the French Society of Pediatric Hematology and ImmunologyNathalie Aladjidi
Unité d Onco Hématologie, Departement de Pediatrie, Hopital des Enfants, Groupe Hospitalier Pellegrin, Place Amelie Raba Leon, 33076 Bordeaux, France
J Clin Oncol 21:4377-85. 2003..The goals of this retrospective study were to determine whether these children could be treated successfully with a salvage regimen and to establish the optimal therapeutic strategy...
Economic evaluation of recombinant human granulocyte colony-stimulating factor in very high-risk childhood acute lymphoblastic leukemiaJean Delorme
Department of Pharmacy, Research Unit INSERM No. 379, France
J Pediatr Hematol Oncol 25:441-7. 2003..The cost benefit of prophylactic treatment by G-CSF relies on the chemotherapeutic regimen given prior to G-CSF administration...
Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. Leucámie Aiqüe Myéloïde EnfantYves Perel
Unité d Onco Hématologie, Departement de Pediatrie, Hopital des Enfants, Groupe Hospitalier Pellegrin, Centres Hospitalo Universitaires de Bordeaux, France
J Clin Oncol 20:2774-82. 2002..To determine whether the use of maintenance therapy (MT) delivered after intensive induction and consolidation therapy confers any advantage in childhood acute myeloid leukemia (AML)...
