Anne Galy

Summary

Country: France

Publications

  1. Majdoul S, Seye A, Kichler A, Holic N, Galy A, Bechinger B, et al. Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells. J Biol Chem. 2016;291:2161-9 pubmed publisher
    ..In conclusion, these results help to decipher the action mechanism of Vectofusin-1 in the context of hCD34+ cell-based gene therapy. ..
  2. Ciré S, Da Rocha S, Ferrand M, Collins M, Galy A. In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice. Mol Ther. 2016;24:1965-1973 pubmed publisher
    ..These results open up new perspectives to further characterize lymph node stromal cell functional properties and to develop gene transfer protocols targeting lymph node stroma to induce peripheral tolerance...
  3. Majdoul S, Cosette J, Seye A, Bernard E, Frin S, Holic N, et al. Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells. J Biol Chem. 2017;292:18672-18681 pubmed publisher
    ..Taken together, our findings suggest that the TB1 and TB2 peptides enhance the viral entry step. Tat-Beclin peptides therefore represent a new family of viral transduction enhancers for potential use in gene therapy. ..

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Collaborators

Detail Information

Publications3

  1. Majdoul S, Seye A, Kichler A, Holic N, Galy A, Bechinger B, et al. Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells. J Biol Chem. 2016;291:2161-9 pubmed publisher
    ..In conclusion, these results help to decipher the action mechanism of Vectofusin-1 in the context of hCD34+ cell-based gene therapy. ..
  2. Ciré S, Da Rocha S, Ferrand M, Collins M, Galy A. In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice. Mol Ther. 2016;24:1965-1973 pubmed publisher
    ..These results open up new perspectives to further characterize lymph node stromal cell functional properties and to develop gene transfer protocols targeting lymph node stroma to induce peripheral tolerance...
  3. Majdoul S, Cosette J, Seye A, Bernard E, Frin S, Holic N, et al. Peptides derived from evolutionarily conserved domains in Beclin-1 and Beclin-2 enhance the entry of lentiviral vectors into human cells. J Biol Chem. 2017;292:18672-18681 pubmed publisher
    ..Taken together, our findings suggest that the TB1 and TB2 peptides enhance the viral entry step. Tat-Beclin peptides therefore represent a new family of viral transduction enhancers for potential use in gene therapy. ..