Research Topics
| A GacouinSummaryCountry: France Publications
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Publications
Severe pneumonia due to Legionella pneumophila: prognostic factors, impact of delayed appropriate antimicrobial therapyA Gacouin
Service de Maladies Infectieuses et de Réanimation Médicale, Hopital Pontchaillou, rue Henri Le Guilloux, 35033 Rennes Cedex, France
Intensive Care Med 28:686-91. 2002..To compare the outcome of patients with severe Legionella pneumonia (LP) according to the presence or absence of prognostic factors currently reported in the literature and delays in initiating fluoroquinolones and macrolides...
Assessment of peri-extubation pain by visual analogue scale in the adult intensive care unit: a prospective observational studyArnaud Gacouin
Service des Maladies Infectieuses et de Réanimation Médicale, Hopital Pontchaillou, rue Henri Le Guilloux, 35000 Rennes, France
Intensive Care Med 30:1340-7. 2004..This prospective observational study was undertaken in order to assess pain experienced by intensive care unit patients at the time of extubation and to identify factors associated with pain of at least moderate intensity...
At-risk drinkers are at higher risk to acquire a bacterial infection during an intensive care unit stay than abstinent or moderate drinkersArnaud Gacouin
Service de Maladies Infectieuses et Reanimation Medicale, Hopital Pontchaillou, Rennes, France
Crit Care Med 36:1735-41. 2008..To determine whether excessive alcohol consumption increases the risk for intensive care unit (ICU)-acquired bacterial infection, especially ventilator-associated pneumonia (VAP), in nontrauma patients...
Chronic alcohol exposure, infection, extended circulating white blood cells differentiated by flow cytometry and neutrophil CD64 expression: a prospective, descriptive study of critically ill medical patientsArnaud Gacouin
CHU Rennes, Maladies infectieuses et réanimation médicale, Rennes, F 35033, France
Ann Intensive Care 2:50. 2012..abstract:..
Distinctive features between community-acquired pneumonia (CAP) due to Chlamydophila psittaci and CAP due to Legionella pneumophila admitted to the intensive care unit (ICU)A Gacouin
Service de Maladies Infectieuses et de Réanimation Médicale, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes, France
Eur J Clin Microbiol Infect Dis 31:2713-8. 2012..Psittacosis is an important differential diagnosis for legionellosis, especially in cases of bird exposure, younger age, and more limited disease progression over the initial few days...
Constipation in long-term ventilated patients: associated factors and impact on intensive care unit outcomesArnaud Gacouin
Service de Maladies Infectieuses et Reanimation Medicale, Hopital Pontchaillou, Rennes, France
Crit Care Med 38:1933-8. 2010....
[Long term survival in chronic obstructive pulmonary disease after ventilation in intensive care]A Gacouin
Service des Maladies Infectieuses et Réanimation Médicale, Hopital Pontchaillou, CHU de Rennes, Universite de Rennes 1, Rennes, France
Rev Mal Respir 26:257-65. 2009..To compare the one year survival after discharge from ICU of patients with chronic obstructive pulmonary disease (COPD) admitted for acute hypercapnic respiratory failure and who required mechanical ventilation...
Reversible spongiform leucoencephalopathy after inhalation of heated heroinArnaud Gacouin
Service des Maladies Infectieuses et de Réanimation Médicale, CHU Rennes, Hopital Pontchaillou, Rue Henri Le Guilloux 35033, Rennes, France
Intensive Care Med 29:1012-5. 2003....
Human herpes virus co-infection is associated with mortality in HIV-negative patients with Pneumocystis jirovecii pneumoniaP Fillatre
Service des Maladies Infectieuses et de Réanimation Médicale, CHU Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
Eur J Clin Microbiol Infect Dis 32:189-94. 2013..4 [4.5-121.9], p < 0.0001). PJP in non-HIV patients remains a serious disease with high in-hospital mortality. Pulmonary co-infection with HSV or CMV may contribute to fatal outcome...
Liver transplantation avoided in patients with fulminant hepatic failure who received albumin dialysis with the molecular adsorbent recirculating system while on the waiting list: impact of the duration of therapyChristophe Camus
Infectious Diseases and Intensive Care Medicine, Pontchaillou Hospital, Rennes, France
Ther Apher Dial 13:549-55. 2009..A minimum duration of therapy (> or =15 h) could be necessary to expect significant liver function improvement...
Prevention of acquired infections in intubated patients with the combination of two decontamination regimensChristophe Camus
Service de Maladies Infectieuses et Reanimation Medicale, Hopital de Pontchaillou, 2 rue Henri Le Guillous, 35033 Rennes Cedex, France
Crit Care Med 33:307-14. 2005..aureus. Because these two regimens could have a complementary role, we evaluated their effects when given both alone and combined...
Late-onset ventilator-associated pneumonia in nontrauma intensive care unit patientsArnaud Gacouin
Service des Maladies Infectieuses et Réanimation Médicale, Hopital Pontchaillou, 35033 Rennes Cedex 9, France
Anesth Analg 109:1584-90. 2009..In this study, we assessed factors associated with late-onset VAP in nontrauma patients and determined whether nutrition provided early was associated with development of late-onset VAP in this population...
Survival of patients with bronchiectasis after the first ICU stay for respiratory failureMathieu Dupont
Service de Réanimation Médicale et Maladies Infectieuses, Service de Pneumologie, Centre Hospitalier Universitaire de Rennes, Rennes, France
Chest 125:1815-20. 2004..Respiratory failure (RF) is a frequent cause of death among patients with bilateral bronchiectasis. An ICU admission is commonly required, and neither short-term or long-term outcomes have been studied...
Molecular adsorbent recirculating system dialysis in patients with acute liver failure who are assessed for liver transplantationChristophe Camus
Service de Maladies Infectieuses et Reanimation Medicale, Hopital Pontchaillou, rue Henri Le Guilloux, CHRU, 2, 35033, Rennes Cedex, France
Intensive Care Med 32:1817-25. 2006..To assess the usefulness of dialysis with the molecular adsorbent recirculating system (MARS) in patients with acute liver failure who fulfil criteria for liver transplantation...
[Acute respiratory distress syndrome related to intra-alveolar hemorrhage revealing a vasculitis]M Kerjouan
Service de Pneumologie, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, 2, rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
Rev Pneumol Clin 68:295-9. 2012..If histology is needed, renal biopsy even without renal involvement, or surgical lung biopsy is possible...
Clinical presentation of leptospirosis: a retrospective study of 34 patients admitted to a single institution in metropolitan FranceS Jaureguiberry
Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Rennes, France
Clin Microbiol Infect 11:391-4. 2005..The study confirmed the variable clinical and biological symptoms of leptospirosis, and indicated that lymphopenia is a common feature of leptospirosis cases...
Fatal coxsackievirus A-16 pneumonitis in adultFrancois Legay
Centre Hospitalier Universitaire Pontchaillou, Rennes, France
Emerg Infect Dis 13:1084-6. 2007..We report a case of fatal pneumonitis in an adult due to a CVA-16 strain with a low (78.6%) rate of sequence homology with the reference strain. A modified, more virulent, strain of CVA-16 could be emerging...
Severe left-sided heart failure early after liver transplantationFrederic Schnell
Service de Cardiologie et Maladies Vasculaires Centre d Investigation Clinique Innovations Technologiques 804, Institut National de la Santé et de la Recherche Médicale Unité 642, Centre Hospitalier Universitaire Rennes, Rennes, France
Liver Transpl 15:1296-305. 2009..In conclusion, LHF after LT carries a high mortality risk and may have different causes. Except for immediate postoperative cases, an infection and an elevated MELD score appear to be determinant...
Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcomeYves Le Tulzo
, , , , France
Shock 18:487-94. 2002..These results suggest that lymphocyte apoptosis is one of the main components of human septic shock immune dysfunction and could be related more to microcirculatory disturbance than to circulating factors...
