- The transcription factor PITX3 is associated with sporadic Parkinson's diseaseJulia Fuchs
Hertie Institute for Clinical Brain Research, Department of Neurodegenerative Diseases, University of Tubingen, Otfried Muller Strasse 27, 72076 Tubingen, Germany
Neurobiol Aging 30:731-8. 2009..004) with PD. The C-allele appears to be a recessive risk allele with an estimated population frequency of 83%. An allele-dependent dysregulation of PITX3 expression might contribute to the susceptibility to PD...
- Genetic variability in the SNCA gene influences alpha-synuclein levels in the blood and brainJulia Fuchs
University of Tubingen, Hertie Institute for Clinical Brain Research, Department of Neurodegenerative Diseases, Hoppe Seyler Str 3, 72076 Tubingen, Germany
FASEB J 22:1327-34. 2008..In conclusion, we provide evidence that alpha-synuclein levels are influenced by genetic variability in the promoter and 3' region of the SNCA gene in vivo...
- Genetic factors influencing age at onset in LRRK2-linked Parkinson diseaseYulia Golub
Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tubingen, Germany
Parkinsonism Relat Disord 15:539-41. 2009....