Nicolas Froger

Summary

Country: France

Publications

  1. ncbi Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations
    Nicolas Froger
    INSERM, U968, Institut de la Vision, Paris, France Sorbonne Universités, Universite Pierre et Marie Curie Paris 6, UMR S 968, Institut de la Vision, Paris, France CNRS, UMR 7210, Institut de la Vision, Paris, France Electronic address
    Prog Retin Eye Res 41:44-63. 2014
  2. pmc Taurine provides neuroprotection against retinal ganglion cell degeneration
    Nicolas Froger
    Institut National de la Santé et de la Recherche Médicale UMR 968, Institut de la Vision, Paris, France
    PLoS ONE 7:e42017. 2012
  3. doi Taurine is a crucial factor to preserve retinal ganglion cell survival
    Nicolas Froger
    INSERM, U968, Institut de la Vision, Paris, France
    Adv Exp Med Biol 775:69-83. 2013
  4. doi Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective
    Nicolas Froger
    Inserm U840, College de France, 11 place Marcelin Berthelot, 75231 Paris, Cedex 05, France
    Mol Cell Neurosci 45:37-46. 2010
  5. ncbi Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments
    Nicolas Froger
    Institut National de la Sante et de la Recherche Medicale, U840, Paris, France
    J Neurochem 111:1383-97. 2009
  6. ncbi Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by beta-amyloid
    William Meme
    INSERM U587, College de France, Paris, France
    FASEB J 20:494-6. 2006
  7. pmc Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells
    David Gaucher
    INSERM, U 968, Insitut de la Vision Retinal Information Processing Pharmacology and Pathologies, 17, rue Moreau, 75012 Paris, France
    Amino Acids 43:1979-93. 2012

Detail Information

Publications7

  1. ncbi Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations
    Nicolas Froger
    INSERM, U968, Institut de la Vision, Paris, France Sorbonne Universités, Universite Pierre et Marie Curie Paris 6, UMR S 968, Institut de la Vision, Paris, France CNRS, UMR 7210, Institut de la Vision, Paris, France Electronic address
    Prog Retin Eye Res 41:44-63. 2014
    ..Along with other antioxidant molecules, taurine should therefore be seriously reconsidered as a potential treatment for such retinal diseases. ..
  2. pmc Taurine provides neuroprotection against retinal ganglion cell degeneration
    Nicolas Froger
    Institut National de la Santé et de la Recherche Médicale UMR 968, Institut de la Vision, Paris, France
    PLoS ONE 7:e42017. 2012
    ..This study indicates that enriched taurine nutrition can directly promote RGC survival through RGC intracellular pathways. It provides evidence that taurine can positively interfere with retinal degenerative diseases...
  3. doi Taurine is a crucial factor to preserve retinal ganglion cell survival
    Nicolas Froger
    INSERM, U968, Institut de la Vision, Paris, France
    Adv Exp Med Biol 775:69-83. 2013
    ..These data suggest that the retinal taurine level is a crucial marker to prevent RGC damage in major retinal diseases...
  4. doi Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective
    Nicolas Froger
    Inserm U840, College de France, 11 place Marcelin Berthelot, 75231 Paris, Cedex 05, France
    Mol Cell Neurosci 45:37-46. 2010
    ..Altogether, these data demonstrate that inflammation-induced astroglial hemichannel activation plays a critical role in neuronal death and suggest a neuroprotective role of connexin43 hemichannel blockade...
  5. ncbi Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments
    Nicolas Froger
    Institut National de la Sante et de la Recherche Medicale, U840, Paris, France
    J Neurochem 111:1383-97. 2009
    ....
  6. ncbi Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by beta-amyloid
    William Meme
    INSERM U587, College de France, Paris, France
    FASEB J 20:494-6. 2006
    ..Thus, the suppression of communication between astrocytes, induced by activated MG could contribute to the proposed role of reactive gliosis in this neurodegenerative disease...
  7. pmc Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells
    David Gaucher
    INSERM, U 968, Insitut de la Vision Retinal Information Processing Pharmacology and Pathologies, 17, rue Moreau, 75012 Paris, France
    Amino Acids 43:1979-93. 2012
    ..Cone photoreceptors and retinal ganglion cells appear as the most sensitive cells to taurine deficiency. These results may explain the recent therapeutic interest of taurine in retinal degenerative pathologies...