N Froger

Summary

Country: France

Publications

  1. ncbi Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice
    Bruno P Guiard
    Laboratoire de Neuropharmacologie EA 3544 MJENR, , , , France
    J Neurochem 89:54-63. 2004
  2. ncbi 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
    N Froger
    Institut National de la Sante et de la Recherche Medicale U288, NeuroPsychoPharmacologie Moléculaire, Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, 75013 Paris, France
    J Neurosci 21:8188-97. 2001
  3. ncbi Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress
    Nicolas Froger
    Institut National de la Santé et de la Recherche Médicale U288 Neuropsychopharmacologie Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, Centre Hospitalier Universitaire Pitie Salpetriere, 75013 Paris, France
    J Neurosci 24:2787-96. 2004
  4. ncbi 5-HT-HPA interactions in two models of transgenic mice relevant to major depression
    L Lanfumey
    INSERM U 288, NeuroPsychoPharmacologie Moléculaire, Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, Paris, France
    Neurochem Res 25:1199-206. 2000
  5. ncbi Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice
    Denis J David
    Laboratoire de Neuropharmacologie Tour D1, 2eme etage, EA 3544 MJENR, Faculté de Pharmacie IFR75 ISIT Institut de Signalisation et d Innovation Thérapeutique, Universite Paris Sud, 5 rue J B Clement, F92296 Châtenay Malabry, France
    Eur J Pharmacol 492:41-8. 2004
  6. ncbi Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice
    Bruno P Guiard
    INSERM/UPMC, NeuroPsychoPharmacologie, , Paris, France
    J Neurochem 95:1713-23. 2005
  7. ncbi Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia
    Mauricio A Retamal
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago 6513492, Chile
    J Neurosci 27:13781-92. 2007

Collaborators

Detail Information

Publications7

  1. ncbi Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice
    Bruno P Guiard
    Laboratoire de Neuropharmacologie EA 3544 MJENR, , , , France
    J Neurochem 89:54-63. 2004
    ..p.) reversed this effect. The present findings suggest that NK1 receptor antagonists, when combined with a SSRI, augment 5-HT release by modulating substance P/5-HT interactions in the dorsal raphe nucleus...
  2. ncbi 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
    N Froger
    Institut National de la Sante et de la Recherche Medicale U288, NeuroPsychoPharmacologie Moléculaire, Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, 75013 Paris, France
    J Neurosci 21:8188-97. 2001
    ..Double immunocytochemical labeling experiments suggest that such a heteroregulation of 5-HT(1A) autoreceptors in NK1-/- mutants does not reflect the existence of direct NK1-5-HT(1A) receptor interactions in normal mice...
  3. ncbi Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress
    Nicolas Froger
    Institut National de la Santé et de la Recherche Médicale U288 Neuropsychopharmacologie Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, Centre Hospitalier Universitaire Pitie Salpetriere, 75013 Paris, France
    J Neurosci 24:2787-96. 2004
    ..These results demonstrate that impaired GR functioning affects normal adaptive responses of the HPA axis and 5-HT system to CMS and alters stress-related consequences on decision-making behaviors...
  4. ncbi 5-HT-HPA interactions in two models of transgenic mice relevant to major depression
    L Lanfumey
    INSERM U 288, NeuroPsychoPharmacologie Moléculaire, Cellulaire et Fonctionnelle, Faculté de Médecine Pitié Salpêtrière, Paris, France
    Neurochem Res 25:1199-206. 2000
    ..These data show that alterations of HPA axis at the gene level has consequences on 5-HT neurotransmission, and reciprocally, that 5-HTT knock-out affects HPA-dependent responses to stress...
  5. ncbi Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice
    Denis J David
    Laboratoire de Neuropharmacologie Tour D1, 2eme etage, EA 3544 MJENR, Faculté de Pharmacie IFR75 ISIT Institut de Signalisation et d Innovation Thérapeutique, Universite Paris Sud, 5 rue J B Clement, F92296 Châtenay Malabry, France
    Eur J Pharmacol 492:41-8. 2004
    ....
  6. ncbi Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice
    Bruno P Guiard
    INSERM/UPMC, NeuroPsychoPharmacologie, , Paris, France
    J Neurochem 95:1713-23. 2005
    ..These data supported the hypothesis that chronic NK1 receptor blockade induces a functional desensitization of 5-HT 1A autoreceptors similar to that observed with SSRIs...
  7. ncbi Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia
    Mauricio A Retamal
    Departamento de Ciencias Fisiologicas, Pontificia Universidad Catolica de Chile, Santiago 6513492, Chile
    J Neurosci 27:13781-92. 2007
    ..Accordingly, this opposite regulation may affect glucose trafficking and certainly will modify the metabolic status of astrocytes involved in brain inflammation...