N Franck

..The results of this study demonstrate a cerebral pattern of activation related to Schneiderian symptoms and reinforce the hypothesis of an involvement of cortical areas that mediate space and body representation in such phenomena...

..The results show that patients bind two consecutive movements more strongly than controls. This anomaly could play a role in the subjective pathological experiences of patients...

..These data are consistent with those reporting that perceptual abilities are spared in schizophrenia while delusions are related to an impairment of a higher level of analysis...

..The possibility that delusions of influence could be related to abnormal recognition of one's own actions was investigated in persons with schizophrenia...

..After rTMS, the patient's hallucinations grew less intrusive and he no longer required isolation. Although the improvement could be a delayed effect of medication, further trials of rTMS in cases of this type appear justified...

..Our data favour the hypothesis that the inability to correctly discriminate between inner and overt speech may play a role in the onset of schizophrenic hallucinations...

..These symptoms, compared to other symptoms of schizophrenia do not reflect general self-recognition impairment but rather a specific impairment of the sense of agency...

..The present case illustrates how the more automatic elementary functions, such as the detection of gaze direction, may be spared in schizophrenic patients, whereas explicit cognitive functions are likely more affected...

..We conclude that the parietal cortex plays an important role in generating and maintaining a kinaesthetic model of ongoing movements...

..This study is the first to show that the direction of movements is a cardinal feature in action attribution, whereas temporal properties of movements play a less important role...

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..These results expand the notion of a working memory deficit in schizophrenia and bear strong implications for understanding executive disorders observed in such patients...

..These results demonstrate that the level of activity of specific brain areas maps onto the experience of causing or controlling an action. The implication of these results for understanding pathological conditions is discussed...

..We will further focus on delusions of alien control in schizophrenic patients. Experimental data suggest that these patients have an abnormal awareness of effort caused by cerebral anomalies in the frontal and parietal lobes...

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..In patients, the ERP waveform was affected during the early part of the response (200 ms). This early effect in schizophrenic patients reveals a modified processing of the visual consequence of their actions...

..This suggests that the experience of alien control observed in certain schizophrenic patients cannot be directly related to an underlying cognitive deficit in the conscious monitoring of their own actions...

..It is proposed that reliable first-person information is necessary to create a stable and coherent motor memory trace...

..These results suggest that the brain computation of the rule operation takes place approximately in the middle of the stimulus-response time interval and that it is an additive process to the sensory association response...

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..We conclude that individuals with schizophrenia do process the configural information of the face. However, further investigations are needed to assert whether this information is of good quality in schizophrenia...

..These results confirm and expand the previously described impairment of patients with schizophrenia in the ability to use rules. They are discussed in terms of deficit in executive functions probably due to frontal lobe malfunctioning...

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..A defective conceptual organisation of perceptive action knowledge would help to explain the severe everyday difficulties of these patients both in monitoring their own actions and in understanding others' intentions...

..A preliminary study has also demonstrated the effectiveness of board games in improving cognitive functioning, which seems to be a highly promising therapeutic avenue owing to its ease of use...

..The selective attention competencies in schizophrenia and the independence hypothesis of emotion and face recognition are discussed in the framework of current face recognition models...

..We discussed these latter results in terms of deficit of the forward model. We emphasized the necessity to distinguish different levels of action, more or less impaired in schizophrenia...

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..We discuss these findings in terms of the role of gamma oscillations in the construction of a sensory representation useful for a correct motor response...

..Frontal scalp negativity was observed, but its latency was longer and its amplitude lower than in the control group. We discuss these findings in terms of the frontoposterior disconnection hypothesis...

..Schizophrenic patients present a generalised deficit for accessing facial information. A facial emotion and an identity-processing deficit are related to negative symptoms. Implications for face-recognition models are discussed...

..The implications of these results for understanding pathological conditions such as schizophrenia are discussed...

..To explore the links between Schneiderian first-rank symptoms (FRS), handedness and speech disorder in subjects with psychosis...

..The detection threshold of centrally generated signals by the higher order level of the motor representation may be abnormally high in these patients...

..The authors conclude that schizophrenic patients have a deficit in processing second-order relational face information...

..In a visual recognition task, this misconnection syndrome might induce a failure to integrate information stored in the frontal and prefrontal sites with incoming stimuli...

..On the other hand, it questions the nature of the memory impairments detected in schizophrenia...

..A disorder of self-monitoring may underlie the positive symptoms of psychosis. The cognitive mechanisms associated with these symptoms may also be detectable in individuals at risk of psychosis...

..Finally, we will address the mechanisms proposed to explain why the illness only presents, on average, 20 years after the initial hypothetical insult...

..Patients may overassociate their actions with subsequent events, experiencing their actions as having unusual causal efficacy. Disorders of agency may reflect an underlying abnormality in the experience of voluntary action...

..Differences in performance across conditions reflect the distinctive contribution of efferent information to self-recognition, and argue against a dominant role of proprioception in self-recognition...