Philippe Fossati

..Our results indicate that personally relevant words may signal important emotional clues and support the notion of a widely distributed set of brain regions involved in maintaining the concepts of self...

..The effects of the repetition of the depressive episodes are not modulated by the subtypes of depression and may reflect sensitization to the cognitive impact of depression associated with increasing prefrontal dysfunction...

..Consolidation electroconvulsive therapy provides new hope for better control of such relapses...

..The authors used functional magnetic resonance imaging (fMRI) to define the neural regions mediating self-referential processing of emotional stimuli and to explore how these regions are influenced by the emotional valence of the stimulus...

..The number of switches in depression was associated with a reduced ability to shift mental set on card sorting tests, suggesting that verbal fluency impairment reflects general executive problems in depression...

..The aim of this study was to investigate if older patients were more vulnerable than younger patients to the impact of depression on memory and if the differences between young and old depressed could be related to executive functioning...

..Since a positive relation between problem-solving deficits and the mean duration of the depressive episode was observed, problem-solving abilities might be predictive of poorer outcome in patients with unipolar affective disorders...

..The aim of this pilot study was to examine whether this pattern was stable over the course of depression...

..Within the CMS, the dorsal MPFC may play a key role in negative affectivity, integrating an increased attention to negative stimuli with an increased attention to the self...

..Additionally, they suggest that measuring life stress exposure is a critical step when imaging genetics...

..These results provide evidence for an extended medial prefrontal network during self-referential processing in major depression, suggesting the involvement of a greater cognitive control...

..Visual perspective and vulnerability for depression may share some biological bases...

..These findings suggest that cognitive avoidance of intrusive memories is associated with a decrease of the episodic components of AM retrieval...

..Our findings suggest that depression may impair the cognitive capacity of depressed patients by recruiting more brain resources than controls during cognitive control...

..We suggest that these 2 patterns reflect the anticipation of the other's behavior and the engagement with others required by social interaction...

..We suggest that this region, by driving the motor cortex, constitutes a brain pathway that allows emotional arousal to facilitate physical effort...

..Specific cognitive interventions may improve the self-relevance of their positive memories...

..Few studies used automated methods such as voxel-based morphometry (VBM) or automated segmentation that can overcome certain drawbacks of manual segmentation (essentially intra- and inter-rater variability and operator time consumption)...

..Follow-up studies are warranted to determine the trait vs. state nature of these biomarkers and their ability to predict treatment outcome...

..Its diagnosis remains a clinical challenge, and depression is one of the main causes of misdiagnoses due to the prevalence of apathy in bvFTD...

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..We suggest that incentive motivation impairment is a core deficit of major depression, which may render everyday tasks abnormally effortful for patients...

..Our results suggest new cognitive interventions to improve the self-relevance of positive memories in depression...

..Results showed that unlike Alzheimer's patients, depressed patients were unable to develop a positive affective bias of judgment for previously heard melodies...

..The hypothesis of this study was that dementia of the Alzheimer type (DAT) patients show an impaired understanding of psychologic cause although they remain able to understand physical causality...

..Our findings highlight the heterogeneity of skills grouped under the term 'executive functions' that are vulnerable in depression or schizophrenia...

..Cognitive functions of adolescents treated with ECT for mood disorder were evaluated at long-term follow-up...

..This exception may be due to the fact that, consequently to the cancer experience as such, this population might already be characterized by a reduced hippocampus with an episodic autobiographical memory deficit...

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..The absence of medial prefrontal deactivation impairment may suggest a preserved mesocortical DA system in these patients...

..The treatment permitted the patient to regain some autonomy with moderate adverse effects. ECT remains an uncommon treatment in adolescents, and the current case supports the view that it should not be banned in young people...

..quot; From a clinical point of view, the consequences of such a phenomenon are manifold:..

..To evaluate the associations between biomechanical, physical, and psychological demands and occupational injury according to depressive symptoms severity...

..The modulation of the mPFC by social information in a memory encoding context could be associated with the initiation of self-referential processes whose contribution is to enhance memory formation...