S Olschwang

Summary

Affiliation: Fondation Jean Dausset
Country: France

Publications

  1. ncbi request reprint [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas]
    S Olschwang
    INSERM U434, CEPH, Paris, France
    Pathol Biol (Paris) 54:215-29. 2006
  2. pmc Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma
    S Olschwang
    INSERM U434, 27 rue Juliette Dodu, 75010 Paris, France
    J Med Genet 38:356-60. 2001
  3. ncbi request reprint Germline mutation profile of the VHL gene in von Hippel-Lindau disease and in sporadic hemangioblastoma
    S Olschwang
    Fondation Jean Dausset CEPH, Paris, France
    Hum Mutat 12:424-30. 1998
  4. doi request reprint [Endometrial cancer in HNPCC syndrome]
    F Lecuru
    Service de Chirurgie Gynécologique et Cancérologique, Hopital Europeen Georges Pompidou, AP HP, Paris, France
    J Gynecol Obstet Biol Reprod (Paris) 37:547-53. 2008
  5. ncbi request reprint Somatically acquired genetic alterations in flat colorectal neoplasias
    S Olschwang
    INSERM U434, C E P H, Paris, France
    Int J Cancer 77:366-9. 1998
  6. ncbi request reprint Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population
    S Olschwang
    Laboratoire de Génétique Moléculaire des Tumeurs, Institut Curie, Paris, France
    Hum Genet 86:369-70. 1991
  7. doi request reprint Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study
    F Lecuru
    Department of Gynecological and Oncological Surgery, Georges Pompidou European Teaching Hospital, Paris, France
    Int J Gynecol Cancer 18:1326-31. 2008
  8. pmc Familial adenomatous polyposis: prevalence of adenomas in the ileal pouch after restorative proctocolectomy
    Y R Parc
    Department of Digestive Surgery, , University Pierre et Marie Curie, Paris, France
    Ann Surg 233:360-4. 2001
  9. ncbi request reprint Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan
    B Zbar
    Laboratory of Immunobiology, Biological Carcinogenesis and Development Program, SAIC Frederick, Maryland, USA
    Hum Mutat 8:348-57. 1996
  10. ncbi request reprint A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
    A Hemminki
    Department of Medical Genetics, Haartman Institute, University of Helsinki, Finland
    Nature 391:184-7. 1998

Collaborators

Detail Information

Publications19

  1. ncbi request reprint [Identification and management of HNPCC syndrome (hereditary non polyposis colon cancer), hereditary predisposition to colorectal and endometrial adenocarcinomas]
    S Olschwang
    INSERM U434, CEPH, Paris, France
    Pathol Biol (Paris) 54:215-29. 2006
    ..Gene carriers will enter a follow-up program regarding their colorectal and endometrial cancer risks, but other organs being at low lifetime risk, no specific surveillance will be proposed...
  2. pmc Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma
    S Olschwang
    INSERM U434, 27 rue Juliette Dodu, 75010 Paris, France
    J Med Genet 38:356-60. 2001
    ..No specific follow up has yet been evaluated for gene carriers. Furthermore, genetic heterogeneity has been reported, which makes genetic counselling difficult...
  3. ncbi request reprint Germline mutation profile of the VHL gene in von Hippel-Lindau disease and in sporadic hemangioblastoma
    S Olschwang
    Fondation Jean Dausset CEPH, Paris, France
    Hum Mutat 12:424-30. 1998
    ....
  4. doi request reprint [Endometrial cancer in HNPCC syndrome]
    F Lecuru
    Service de Chirurgie Gynécologique et Cancérologique, Hopital Europeen Georges Pompidou, AP HP, Paris, France
    J Gynecol Obstet Biol Reprod (Paris) 37:547-53. 2008
    ..Screening of endometrial cancer remains the main objective of the management of those patients. Endometrial biopsy should have a larger place...
  5. ncbi request reprint Somatically acquired genetic alterations in flat colorectal neoplasias
    S Olschwang
    INSERM U434, C E P H, Paris, France
    Int J Cancer 77:366-9. 1998
    ..With the exception of a low KRAS mutation rate, flat adenomas appear to follow tumorigenesis pathways very similar to those identified in exophytic adenomas and carcinomas...
  6. ncbi request reprint Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population
    S Olschwang
    Laboratoire de Génétique Moléculaire des Tumeurs, Institut Curie, Paris, France
    Hum Genet 86:369-70. 1991
    ..We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer...
  7. doi request reprint Performance of office hysteroscopy and endometrial biopsy for detecting endometrial disease in women at risk of human non-polyposis colon cancer: a prospective study
    F Lecuru
    Department of Gynecological and Oncological Surgery, Georges Pompidou European Teaching Hospital, Paris, France
    Int J Gynecol Cancer 18:1326-31. 2008
    ..However, diagnostic hysteroscopy ensured the diagnosis of endometrial adenocarcinoma in HNPCC women with bleeding. Nevertheless, usefulness and optimal modalities of screening remain to be determined...
  8. pmc Familial adenomatous polyposis: prevalence of adenomas in the ileal pouch after restorative proctocolectomy
    Y R Parc
    Department of Digestive Surgery, , University Pierre et Marie Curie, Paris, France
    Ann Surg 233:360-4. 2001
    ..Regular endoscopic surveillance of the pouch is recommended at a frequency similar to that of upper gastrointestinal endoscopy...
  9. ncbi request reprint Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan
    B Zbar
    Laboratory of Immunobiology, Biological Carcinogenesis and Development Program, SAIC Frederick, Maryland, USA
    Hum Mutat 8:348-57. 1996
    ..The catalog of VHL germline mutations with phenotype information should be useful for diagnostic and prognostic studies of VHL and for studies of genotype-phenotype correlations in VHL...
  10. ncbi request reprint A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
    A Hemminki
    Department of Medical Genetics, Haartman Institute, University of Helsinki, Finland
    Nature 391:184-7. 1998
    ..Peutz-Jeghers syndrome is therefore the first cancer-susceptibility syndrome to be identified that is due to inactivating mutations in a protein kinase...
  11. ncbi request reprint [Phenotype-genotype study in 154 French NF2 mutation carriers]
    L Demange
    Centre Rene Huguenin, Saint Cloud, France
    Rev Neurol (Paris) 163:1031-8. 2007
    ..To assess whether the phenotypic variability of neurofibromatosis 2 could be linked to genotype, clinical data of 154 patients whose NF2 germline alteration had been identified in our laboratory have been collected...
  12. ncbi request reprint Turcot syndrome confirmed with molecular analysis
    C Lebrun
    Service de Neurologie, Hopital Pasteur, Nice, France
    Eur J Neurol 14:470-2. 2007
    ..The subsequent molecular characterization may contribute to the appropriate care of affected patients and asymptomatic gene carriers...
  13. ncbi request reprint Alleles of the APC gene: an attenuated form of familial polyposis
    L Spirio
    Department of Human Genetics, Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112
    Cell 75:951-7. 1993
    ..However, they differ in that the four mutated sites are located very close to one another and nearer the 5' end of the APC gene than any base substitutions or small deletions yet discovered in patients with classical APC...
  14. ncbi request reprint [HNPCC syndrome (hereditary non polyposis colon cancer): identification and management]
    S Olschwang
    Institut Paoli Calmettes, INSERM UMR 599, 232, boulevard Sainte Marguerite, 13009 Marseille, France
    Rev Med Interne 26:109-18. 2005
    ..Gene carriers will enter a follow-up program regarding their colorectal and endometrial cancer risks; other organs being at low lifetime risk, no specific surveillance will be proposed...
  15. pmc An alternative to prophylactic colectomy for colon cancer prevention in HNPCC syndrome
    S Olschwang
    Gut 54:169. 2005
  16. pmc Screening for genomic rearrangements of the MMR genes must be included in the routine diagnosis of HNPCC
    F Di Fiore
    J Med Genet 41:18-20. 2004
  17. pmc Immunohistochemical analysis of adenocarcinoma of the small intestine: a tissue microarray study
    M Svrcek
    Department of Pathology, Saint Antoine Hospital, AP HP, F75571 Paris Cedex 12, France
    J Clin Pathol 56:898-903. 2003
    ..Primary adenocarcinomas of the small intestine are rare, and the genetic mechanisms involved in their carcinogenesis remain unclear...
  18. ncbi request reprint PTEN germ-line mutations in juvenile polyposis coli
    S Olschwang
    Nat Genet 18:12-4. 1998
  19. pmc Cancer risk in 348 French MSH2 or MLH1 gene carriers
    Y Parc
    J Med Genet 40:208-13. 2003