Jean Feuillard

Summary

Country: France

Publications

  1. ncbi request reprint Inducible loss of NF-kappaB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes
    J Feuillard
    Biochimie Cellulaire des Hémopathies Lymphoïdes, Universite Paris, Bobigny, France
    Blood 95:2068-75. 2000
  2. ncbi request reprint Clinical and biologic features of CD4(+)CD56(+) malignancies
    Jean Feuillard
    Service d Hematologie Biologique, Hopital Avicenne, Université Paris 13 Bobigny, France
    Blood 99:1556-63. 2002
  3. pmc Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells
    Imen Najjar
    UPRES EA 34306, Service de Biochimie, AP HP, Hopital Avicenne, 125 rue de Stalingrad, 93009 Bobigny Cedex, France
    J Virol 79:4936-43. 2005
  4. doi request reprint Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha
    Imen Najjar
    Universite Paris 13, EA 3406, Service de Biochimie, APHP, Hopital Avicenne, Cedex, France
    J Leukoc Biol 84:1604-12. 2008
  5. ncbi request reprint Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells
    Fanny Baran-Marszak
    EA 3406 Université Paris 13, Service de Biochimie, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny Cedex, France
    Blood 104:2475-83. 2004
  6. ncbi request reprint Lymphoma complicating common variable immunodeficiency with granulomatous disease: report of two cases
    Véronique Le Guern
    Department of Internal Medicine, Hopital Avicenne, Assistance Publique Hôpitaux de Paris and Université Paris Nord, Bobigny, France
    Eur J Haematol 71:459-63. 2003
  7. ncbi request reprint Resistance to fludarabine-induced apoptosis in Epstein-Barr virus infected B cells
    Remi Fagard
    EA 3406 ATHSCO, Université Paris 13 UFR SMBH Bobigny cedex, France
    Oncogene 21:4473-80. 2002
  8. ncbi request reprint Gene array identification of Epstein Barr virus-regulated cellular genes in EBV-converted Burkitt lymphoma cell lines
    Fanny Baran-Marszak
    Service d Hematologie Biologique, Hôpital Avicenne AP HP et EA 3406 ATHSCO Université Paris 13, Bobigny, France
    Lab Invest 82:1463-79. 2002
  9. ncbi request reprint Immunoproliferative small intestinal disease associated with Campylobacter jejuni
    Marc Lecuit
    Hopital Avicenne, Paris, France
    N Engl J Med 350:239-48. 2004
  10. ncbi request reprint Immunophenotypic clustering of myelodysplastic syndromes
    Marc Maynadie
    Service d Hematologie Biologique, CHU Bocage, Dijon, France
    Blood 100:2349-56. 2002

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Inducible loss of NF-kappaB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes
    J Feuillard
    Biochimie Cellulaire des Hémopathies Lymphoïdes, Universite Paris, Bobigny, France
    Blood 95:2068-75. 2000
    ..Finally, our results suggest that a cellular model with doxycycline-inducible IkappaBalpha(32/36A) may be useful in the identification of genuine NF-kappaB target genes in EBV-infected B cells. (Blood. 2000;95:2068-2075)..
  2. ncbi request reprint Clinical and biologic features of CD4(+)CD56(+) malignancies
    Jean Feuillard
    Service d Hematologie Biologique, Hopital Avicenne, Université Paris 13 Bobigny, France
    Blood 99:1556-63. 2002
    ..Finally, relationships between the pure cutaneous indolent form of the disease and acute leukemia as well as with the lymphoid/myeloid origin of the CD4(+)CD56(+) malignant cell are discussed...
  3. pmc Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells
    Imen Najjar
    UPRES EA 34306, Service de Biochimie, AP HP, Hopital Avicenne, 125 rue de Stalingrad, 93009 Bobigny Cedex, France
    J Virol 79:4936-43. 2005
    ..Whether this response, which is usually considered to be antiviral, is in fact required for the persistence of the virus remains to be elucidated...
  4. doi request reprint Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha
    Imen Najjar
    Universite Paris 13, EA 3406, Service de Biochimie, APHP, Hopital Avicenne, Cedex, France
    J Leukoc Biol 84:1604-12. 2008
    ..These data reveal a novel role of STAT1beta in programmed cell death, which is independent of p53...
  5. ncbi request reprint Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells
    Fanny Baran-Marszak
    EA 3406 Université Paris 13, Service de Biochimie, Hopital Avicenne, 125 route de Stalingrad, 93009 Bobigny Cedex, France
    Blood 104:2475-83. 2004
    ....
  6. ncbi request reprint Lymphoma complicating common variable immunodeficiency with granulomatous disease: report of two cases
    Véronique Le Guern
    Department of Internal Medicine, Hopital Avicenne, Assistance Publique Hôpitaux de Paris and Université Paris Nord, Bobigny, France
    Eur J Haematol 71:459-63. 2003
    ..We describe two CVID patients with systemic granulomatosis who developed B-cell lymphomas, one related to Epstein Barr virus infection, 5 and 12 yr after CVID had been diagnosed...
  7. ncbi request reprint Resistance to fludarabine-induced apoptosis in Epstein-Barr virus infected B cells
    Remi Fagard
    EA 3406 ATHSCO, Université Paris 13 UFR SMBH Bobigny cedex, France
    Oncogene 21:4473-80. 2002
    ..8 cells. Finally, the expression of p21WAF1/CIP1 was detected only in the BL2.B95.8 and PRI cells. This protein, known to play a role in cell survival, may therefore be involved in the resistance of the BL2.B95.8 cells to fludarabine...
  8. ncbi request reprint Gene array identification of Epstein Barr virus-regulated cellular genes in EBV-converted Burkitt lymphoma cell lines
    Fanny Baran-Marszak
    Service d Hematologie Biologique, Hôpital Avicenne AP HP et EA 3406 ATHSCO Université Paris 13, Bobigny, France
    Lab Invest 82:1463-79. 2002
    ..Furthermore, and perhaps most importantly, cDNA array results point to three families of transcription factors, Rel/NF-kappaB, STAT1, and Ets-related proteins Spi-B, Elf-1, and Ets-1 as putative cellular targets of EBV...
  9. ncbi request reprint Immunoproliferative small intestinal disease associated with Campylobacter jejuni
    Marc Lecuit
    Hopital Avicenne, Paris, France
    N Engl J Med 350:239-48. 2004
    ..Early-stage disease responds to antibiotics, suggesting a bacterial origin. We attempted to identify a causative agent...
  10. ncbi request reprint Immunophenotypic clustering of myelodysplastic syndromes
    Marc Maynadie
    Service d Hematologie Biologique, CHU Bocage, Dijon, France
    Blood 100:2349-56. 2002
    ..These results show a close relationship between immunophenotypic abnormalities and BM dysplasia and suggest that flow cytometry could be a future tool for the characterization of MDSs...
  11. ncbi request reprint C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma
    Martin Schlee
    Institute of Clinical Molecular Biology and Tumor Genetics, GSF National Research Center for Environment and Health, Munchen, Germany
    Int J Cancer 120:1387-95. 2007
    ..c-MYC thus masks an interferon-inducing activity in these cells. Our findings imply that immune escape of tumor cells is not only a matter of in vivo selection but may be additionally promoted by activation of a cellular oncogene...
  12. ncbi request reprint A simple method for detection of major phenotypic abnormalities in myelodysplastic syndromes: expression of CD56 in CMML
    Charlotte Lacronique-Gazaille
    Haematologica 92:859-60. 2007
    ..CD56 on monocytes was associated with CMML. Importantly, phenotypic aberrations were lost on blood cells, except for CD56...
  13. pmc Molecular basis of cytotoxicity of Epstein-Barr virus (EBV) latent membrane protein 1 (LMP1) in EBV latency III B cells: LMP1 induces type II ligand-independent autoactivation of CD95/Fas with caspase 8-mediated apoptosis
    Christophe Le Clorennec
    UMR CNRS 6101, Faculte de Medecine, 2 rue du Docteur Marchand, 87025 Limoges Cedex, France
    J Virol 82:6721-33. 2008
    ....
  14. ncbi request reprint [Hematodermic CD4/CD56 neoplasm]
    Tony Petrella
    Centre de Pathologie, 33 rue Nicolas Bornier, BP189, 21005, Dijon Cedex, France
    Ann Pathol 24:241-55; quiz 227. 2004
    ..The median time of survival is 14 months irrespective of the treatment given. Conventional chemotherapies used for the treatment of aggressive lymphomas or acute myeloid leukemias are quickly inefficient...
  15. ncbi request reprint CD4+ CD56+ lineage negative malignancies: a new entity developed from malignant early plasmacytoid dendritic cells
    Marie Christine Jacob
    EFS Rhone Alpes, Dept of Cellular Immunology, Grenoble, France
    Haematologica 88:941-55. 2003
    ..The clinico-biological features of this neoplasm were moreover recently summarized from a large series of 23 patients...
  16. ncbi request reprint The CD4+ CD56+ CD116- CD123+ CD45RA+ CD45RO- profile is specific of DC2 malignancies
    Franck Trimoreau
    Haematologica 88:ELT10. 2003
  17. ncbi request reprint Plasmacytoid dendritic cells: from the plasmacytoid T-cell to type 2 dendritic cells CD4+CD56+ malignancies
    Marie C Bene
    Laboratoire d Immunologie du CHU, Nancy, France
    Semin Hematol 40:257-66. 2003
    ..The major characteristics of DC2 malignancies are summarized and compared to natural killer cell (NK) lymphomas, another type of proliferative disease sharing the expression of CD56...
  18. pmc The mutator pathway is a feature of immunodeficiency-related lymphomas
    Alex Duval
    Institut National de la Santé et de la Recherche Médicale U434, Centre d Etude du Polymorphisme Humain, 75010 Paris, France
    Proc Natl Acad Sci U S A 101:5002-7. 2004
    ..Because MSI-H-positive cases were found to be either Epstein-Barr virus-positive or -negative, the mutator pathway should act synergistically or not with this other oncogenic factor, playing an important role in ID-RL...
  19. ncbi request reprint Successful rituximab treatment of an EBV-related lymphoproliferative disease arising after autologous transplantation for angioimmunoblastic T-cell lymphoma
    Sophie Park
    Laboratoire d Hematologie, Hôpital Saint Louis AP HP, Paris, France
    Hematol J 3:317-20. 2002
    ..This case is discussed in the context of severe immunodepression. Monoclonal anti-CD20 antibodies might restore a balance between T-cell immunosurveillance and EBV proliferation in B-cells,..
  20. doi request reprint Multicenter study of ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia using an optimized flow cytometry method
    Nathalie Gachard
    Laboratoire d Hematologie, CHU Dupuytren, Faculté de Médecine de Limoges, Universite de Limoges, Centre National de Recherche Scientifique, UMR CNRS 6101, France
    Haematologica 93:215-23. 2008
    ..Flow cytometry allows specific assessment of the expression of ZAP-70, a promising new prognostic factor in B-cell chronic lymphocytic leukemia (B-CLL), but suffers from a lack of multicenter standardization...
  21. ncbi request reprint "6 markers/5 colors" extended white blood cell differential by flow cytometry
    Jean Luc Faucher
    Laboratoire d Hematologie, hôpital Dupuytren, Limoges, France
    Cytometry A 71:934-44. 2007
    ....
  22. ncbi request reprint Plasmacytoid dendritic cell leukaemia/lymphoma: towards a well defined entity?
    Francine Garnache-Ottou
    EFS BFC, Haematology and Immunology Laboratory, Besancon, France
    Br J Haematol 136:539-48. 2007
    ..g. T-cell leukaemia 1)--blood dendritic cell antigen-2 and high levels of CD123 expression as potential markers. In addition, we propose a multidisciplinary approach including several fields of haematology to improve pDCL diagnosis...
  23. pmc Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways
    Gautier Goormachtigh
    CNRS UMR 8527, Institut de Biologie de Lille IBL, 1 rue du Pr Calmette, 59021 Lille Cedex, France
    J Virol 80:7382-93. 2006
    ..Finally, we show that this autoactivation is the most important mechanism to maintain LMP1 expression during the type II latency program of EBV...
  24. ncbi request reprint Effect of tumor necrosis factor alpha and infliximab on apoptosis of B lymphocytes infected or not with Epstein-Barr virus
    Fanny Baran-Marszak
    INSERM E109, CHU Bicetre, Assistance Publique Hopitaux de Paris, Université Paris 11, 94275 Le Kremlin Bicetre, France
    Cytokine 33:337-45. 2006
    ..Thus, if an increased incidence of lymphoma were induced by TNFalpha blockers, it would not involve a direct effect on B cells but rather an impaired immune surveillance by T cells...
  25. ncbi request reprint EBV latency III immortalization program sensitizes B cells to induction of CD95-mediated apoptosis via LMP1: role of NF-kappaB, STAT1, and p53
    Christophe Le Clorennec
    Centre National de la Recherche Scientifique, Unité Mixte de Recherche UMR CNRS 6101, Faculté de Médecine de Limoges, Universite de Limoges, Centre Hospitalier Universitaire CHU Dupuytren, Laboratoire d Hematologie, Limoges, France
    Blood 107:2070-8. 2006
    ....
  26. pmc Stringent doxycycline-dependent control of gene activities using an episomal one-vector system
    Georg W Bornkamm
    GSF Institut für Klinische Molekularbiologie und Tumorgenetik, Marchioninistrasse 25, D 81377 Munchen, Germany
    Nucleic Acids Res 33:e137. 2005
    ..Tight down regulation is achieved through binding of the silencer tTS(KRAB) to P(tet)bi-1 in the absence of Dox. Addition of Dox releases repression and via binding of rtTA2(S)-M2 activates P(tet)bi-1...
  27. ncbi request reprint PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor
    Rosa Ana Gonzalez-Polo
    1Centre National de la Recherche Scientifique, UMR8125, Institut Gustave Roussy, Pavillon de Recherche 1, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Oncogene 24:7503-13. 2005
    ..Thus, PK11195 potently sensitizes to apoptosis via a pathway that involves mitochondria, yet does not involve the PBR...
  28. ncbi request reprint Indolent lymphoplasmacytic and marginal zone B-cell lymphomas: absence of both IRF4 and Ki67 expression identifies a better prognosis subgroup
    Barbara Petit
    Laboratoire d Anatomie Pathologique, France
    Haematologica 90:200-6. 2005
    ..The existence of rather aggressive cases stresses the need for new biological prognostic markers...
  29. ncbi request reprint The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family
    Patricia Boya
    Centre National de la Recherche Scientifique, UMR8125, Institut Gustave Roussy, Villejuif, France
    Oncogene 22:6220-30. 2003
    ..Altogether, these data indicate that 4-HPR induces MMP through an ROS-mediated pathway that involves the obligatory contribution of the proapopotic Bcl-2 family members Bax and/or Bak...
  30. ncbi request reprint CD4(+), CD56(+) DC2 acute leukemia is characterized by recurrent clonal chromosomal changes affecting 6 major targets: a study of 21 cases by the Groupe Français de Cytogénétique Hématologique
    Dominique Leroux
    Laboratoire d hématologie cellulaire et moléculaire, Centre Hospitalier Universitaire CHU Michallon, Grenoble, France
    Blood 99:4154-9. 2002
    ..In conclusion, the present study documents for the first time the existence of a characteristic cytogenetic profile for this novel disease entity...