Marie Anne Felix

Summary

Country: France

Publications

  1. ncbi request reprint A gonad-derived survival signal for vulval precursor cells in two nematode species
    M A Felix
    HHMI and Division of Biology 156 29, Caltech, Pasadena, California 91125, USA
    Curr Biol 8:287-90. 1998
  2. ncbi request reprint Cryptic quantitative evolution of the vulva intercellular signaling network in Caenorhabditis
    Marie Anne Felix
    Institut Jacques Monod, Centre National de la Recherche Scientifique, Universities of Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Curr Biol 17:103-14. 2007
  3. ncbi request reprint Robustness and evolution: concepts, insights and challenges from a developmental model system
    M A Felix
    Institut Jacques Monod, CNRS Universities of Paris 6 7, Paris, France
    Heredity (Edinb) 100:132-40. 2008
  4. ncbi request reprint An inversion in the wiring of an intercellular signal: evolution of Wnt signaling in the nematode vulva
    Marie Anne Felix
    Institut Jacques Monod, CNRS University of Paris 6 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Bioessays 27:765-9. 2005
  5. ncbi request reprint Evolvability of cell specification mechanisms
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universités Paris 6 and 7, 75251 Paris Cedex 05, France
    J Exp Zool B Mol Dev Evol 304:536-47. 2005
  6. pmc RNA interference in nematodes and the chance that favored Sydney Brenner
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universities of Paris 7 and 6, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    J Biol 7:34. 2008
  7. ncbi request reprint Genomes: a helpful cousin for our favourite worm
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universités Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Curr Biol 14:R75-7. 2004
  8. ncbi request reprint Alternative morphs and plasticity of vulval development in a rhabditid nematode species
    Marie Anne Felix
    Institut Jacques Monod, CNRS, Universités Paris 6 et 7, Tour 43, 2 place Jussieu, 75251, Paris Cedex 05, France
    Dev Genes Evol 214:55-63. 2004
  9. ncbi request reprint Evolution of developmental mechanisms in nematodes
    M A Felix
    Institut Jacques Monod, CNRS Universités Paris 6 et 7, France
    J Exp Zool 285:3-18. 1999
  10. ncbi request reprint High local genetic diversity and low outcrossing rate in Caenorhabditis elegans natural populations
    Antoine Barrière
    Institut Jacques Monod, Centre National de la Recherche Scientifique, Universities Paris 6 and 7, Paris, France
    Curr Biol 15:1176-84. 2005

Collaborators

Detail Information

Publications34

  1. ncbi request reprint A gonad-derived survival signal for vulval precursor cells in two nematode species
    M A Felix
    HHMI and Division of Biology 156 29, Caltech, Pasadena, California 91125, USA
    Curr Biol 8:287-90. 1998
    ..Our results demonstrate the existence of intercellular cell-survival signals in nematodes and uncover an evolutionary variation in the role of the gonad in nematode vulval development...
  2. ncbi request reprint Cryptic quantitative evolution of the vulva intercellular signaling network in Caenorhabditis
    Marie Anne Felix
    Institut Jacques Monod, Centre National de la Recherche Scientifique, Universities of Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Curr Biol 17:103-14. 2007
    ..It is unknown how the roles and quantitative contributions of these signaling pathways have evolved in closely related Caenorhabditis species...
  3. ncbi request reprint Robustness and evolution: concepts, insights and challenges from a developmental model system
    M A Felix
    Institut Jacques Monod, CNRS Universities of Paris 6 7, Paris, France
    Heredity (Edinb) 100:132-40. 2008
    ..Part of the reason is that highly robust systems can accumulate cryptic variation that can serve as a source of new adaptations and evolutionary innovations. We point to some key challenges in improving our understanding of robustness...
  4. ncbi request reprint An inversion in the wiring of an intercellular signal: evolution of Wnt signaling in the nematode vulva
    Marie Anne Felix
    Institut Jacques Monod, CNRS University of Paris 6 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Bioessays 27:765-9. 2005
    ..Strikingly,a recent study finds that Wnts act to repress vulval differentiation in the nematode Pristionchus pacificus,1 demonstrating evolutionary flexibility in the use of intercellular signaling pathways...
  5. ncbi request reprint Evolvability of cell specification mechanisms
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universités Paris 6 and 7, 75251 Paris Cedex 05, France
    J Exp Zool B Mol Dev Evol 304:536-47. 2005
    ..We finally discuss ways in which selection pressures on phenotypes can be inferred from a comparison of the phenotypic spectrum found on mutation with that found in the wild...
  6. pmc RNA interference in nematodes and the chance that favored Sydney Brenner
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universities of Paris 7 and 6, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    J Biol 7:34. 2008
    ....
  7. ncbi request reprint Genomes: a helpful cousin for our favourite worm
    Marie Anne Felix
    Institut Jacques Monod, CNRS Universités Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Curr Biol 14:R75-7. 2004
    ..The recently published genome of the nematode Caenorhabditis briggsae provides a drastic improvement in structural annotation of the C. elegans genome, as well as a promising source of evolutionary comparisons...
  8. ncbi request reprint Alternative morphs and plasticity of vulval development in a rhabditid nematode species
    Marie Anne Felix
    Institut Jacques Monod, CNRS, Universités Paris 6 et 7, Tour 43, 2 place Jussieu, 75251, Paris Cedex 05, France
    Dev Genes Evol 214:55-63. 2004
    ..the number, timing, and source of inductive signals from the gonad to the vulval precursor cells differ between the two morphs. These results show that discrete vulva developmental routes can be adopted by animals of the same genotype...
  9. ncbi request reprint Evolution of developmental mechanisms in nematodes
    M A Felix
    Institut Jacques Monod, CNRS Universités Paris 6 et 7, France
    J Exp Zool 285:3-18. 1999
    ....
  10. ncbi request reprint High local genetic diversity and low outcrossing rate in Caenorhabditis elegans natural populations
    Antoine Barrière
    Institut Jacques Monod, Centre National de la Recherche Scientifique, Universities Paris 6 and 7, Paris, France
    Curr Biol 15:1176-84. 2005
    ..In particular, its unusual mode of reproduction with self-fertile hermaphrodites and facultative males raises the question of its frequency of outcrossing in natural populations...
  11. ncbi request reprint Mechanisms and evolution of environmental responses in Caenorhabditis elegans
    Christian Braendle
    Institut Jacques Monod, CNRS Universities of Paris 6 7, Tour 43 2 Place Jussieu, 75251 Paris Cedex 05, France
    Curr Top Dev Biol 80:171-207. 2008
    ..Second, we discuss the development of the C. elegans vulva. This example illustrates how development responds to variation in the environment while generating an invariant final phenotype...
  12. ncbi request reprint The other side of phenotypic plasticity: a developmental system that generates an invariant phenotype despite environmental variation
    Christian Braendle
    Institut Jacques Monod, CNRS University of Paris 6, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    J Biosci 34:543-51. 2009
    ..Fourth, we discuss the evolutionary significance of environmental sensitivity of this developmental system...
  13. doi request reprint High sensitivity of C. elegans vulval precursor cells to the dose of posterior Wnts
    Jean Baptiste Pénigault
    Institut Jacques Monod, CNRS University Paris Diderot, 15 Rue Hélène Brion, 75205 Paris Cedex 13, France
    Dev Biol 357:428-38. 2011
    ..p competence without affecting their LIN-39 level. The centered vulval competence profile is thus under the control of the posterior Wnts and of cross-regulation of three HOM-C genes and prepatterns the later induction of vulval fates...
  14. pmc Bias and evolution of the mutationally accessible phenotypic space in a developmental system
    Christian Braendle
    Institut Jacques Monod, CNRS Universite Paris Diderot, Paris, France
    PLoS Genet 6:e1000877. 2010
    ..This study provides an empirical assessment of developmental bias and the evolution of mutationally accessible phenotypes and supports the notion that such bias may influence the directions of evolutionary change...
  15. ncbi request reprint Sex determination: ways to evolve a hermaphrodite
    Christian Braendle
    Institut Jacques Monod, CNRS Universités Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Curr Biol 16:R468-71. 2006
    ..elegans and C. briggsae, however, produce self-fertile hermaphrodites instead of females. These transitions to hermaphroditism evolved convergently through distinct modifications of germline sex determination mechanisms...
  16. doi request reprint Evolution of a system sensitive to stochastic noise: P3.p cell fate in Caenorhabditis
    Jean Baptiste Pénigault
    Institut Jacques Monod, CNRS University Paris Diderot, 15 Rue Hélène Brion, 75205 Paris Cedex 13, France
    Dev Biol 357:419-27. 2011
    ..briggsae. We propose that evolutionary variation in the concentration or interpretation of the long-range Wnt gradient may be involved in the rapid evolution of P3.p fate in Caenorhabditis...
  17. pmc Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae
    Marie Anne Felix
    Institut Jacques Monod, CNRS University of Paris VII, France
    BMC Biol 10:59. 2012
    ..Very little is known, however, about its ecology, including where it proliferates. In the past, C. elegans was mainly isolated from human-made compost heaps, where it was overwhelmingly found in the non-feeding dauer diapause stage...
  18. pmc Role of pleiotropy in the evolution of a cryptic developmental variation in Caenorhabditis elegans
    Fabien Duveau
    Institut Jacques Monod, Paris, France
    PLoS Biol 10:e1001230. 2012
    ..In addition, cultivation in the laboratory has led to adaptive evolution of the reference strain N2 to the laboratory environment, which may modify other phenotypes of interest...
  19. ncbi request reprint The two steps of vulval induction in Oscheius tipulae CEW1 recruit common regulators including a MEK kinase
    Marie Laure Dichtel-Danjoy
    Institut Jacques Monod, 75251 Paris Cedex 05, France
    Dev Biol 265:113-26. 2004
    ..Finally, a comparison of vulval mutant phenotypes obtained in C. elegans and O. tipulae CEW1 highlights the evolution of vulval induction mechanisms between the two species...
  20. ncbi request reprint Phenotypic neighborhood and micro-evolvability
    Marie Laure Dichtel-Danjoy
    Institut Jacques Monod, CNRS Universités Paris 6 et 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Trends Genet 20:268-76. 2004
  21. pmc Temporal dynamics and linkage disequilibrium in natural Caenorhabditis elegans populations
    Antoine Barrière
    Institut Jacques Monod, CNRS Universities of Paris 6 and 7, 75251 Paris Cedex 05, France
    Genetics 176:999-1011. 2007
    ..C. elegans seems to follow metapopulation dynamics, and the maintenance of linkage disequilibrium despite a low yet significant level of outcrossing suggests that selection may act against the progeny of outcrossings...
  22. pmc Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest
    Marie Anne Felix
    Institut de Biologie Valrose, CNRS, UMR7277, Parc Valrose, Nice Cedex 02, 06108, France
    BMC Evol Biol 13:10. 2013
    ..elegans developmental biology and molecular genetics, biologists lack basic data for understanding the abundance and distribution of Caenorhabditis species in natural areas that are unperturbed by human influence...
  23. pmc Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses
    Marie Anne Felix
    Institut Jacques Monod, CNRS University of Paris Diderot, Paris, France
    PLoS Biol 9:e1000586. 2011
    ..This discovery establishes a bona fide viral infection system to explore the natural ecology of nematodes, host-pathogen co-evolution, the evolution of small RNA responses, and innate antiviral mechanisms...
  24. doi request reprint Plasticity and errors of a robust developmental system in different environments
    Christian Braendle
    Institut Jacques Monod, CNRS University Denis Diderot Paris 7 UPMC, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Dev Cell 15:714-24. 2008
    ....
  25. pmc Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes
    Isabelle Nuez
    Institut Jacques Monod, Centre National de la Recherche Scientifique Université Paris Diderot, Paris, France
    PLoS ONE 7:e29811. 2012
    ..elegans sid-2 gene. Here we aimed to elucidate the evolution of the susceptibility to external RNAi in the Caenorhabditis genus...
  26. doi request reprint [Genetic and environmental variations in an intercellular signaling network]
    Marie Anne Felix
    Institut Jacques Monod, CNRS Université Paris 7 Denis Diderot, 15, rue Hélène Brion, 75205 Paris Cedex 13, France
    Med Sci (Paris) 25:705-12. 2009
    ..Like every biological system, this network displays genetic and -environmental epistasis...
  27. doi request reprint Oscheius tipulae, a widespread hermaphroditic soil nematode, displays a higher genetic diversity and geographical structure than Caenorhabditis elegans
    Dorothée Baïlle
    Institut Jacques Monod, CNRS Universities of Paris 6 and 7, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Mol Ecol 17:1523-34. 2008
    ..Due to its widespread occurrence and relatively high genetic diversity, O. tipulae may be a promising study species for evolutionary studies...
  28. pmc Control of vulval competence and centering in the nematode Oscheius sp. 1 CEW1
    Sophie Louvet-Vallee
    Institut Jacques Monod, CNRS Universités Paris 6 et 7, 75251 Paris Cedex 05, France
    Genetics 163:133-46. 2003
    ..p competence. Group 4 mutants display an abnormal centering of the vulval pattern on P7.p and suggest that a specific mechanism centers the vulval pattern on a single Pn.p cell...
  29. pmc Intraspecific evolution of the intercellular signaling network underlying a robust developmental system
    Josselin Milloz
    Institut Jacques Monod, CNRS University Denis Diderot Paris 7 UPMC, Paris, France
    Genes Dev 22:3064-75. 2008
    ..In addition, our results suggest that the vulva genetic screens would have yielded a different mutation spectrum, especially for Wnt pathway mutations, had they been performed in another C. elegans genetic background...
  30. pmc Control of vulval cell division number in the nematode Oscheius/Dolichorhabditis sp. CEW1
    M L Dichtel
    Institut Jacques Monod, , 75251 Paris Cedex 05, France
    Genetics 157:183-97. 2001
    ..CEW1 appear to be redundantly controlled by a gonad-independent mechanism and by a gonadal signal that operates partially independently of vulval fate induction...
  31. ncbi request reprint Development and evolution of a variable left-right asymmetry in nematodes: the handedness of P11/P12 migration
    M Delattre
    Institut Jacques Monod, CNRS, , Tour 43, 2 place Jussieu, Paris Cedex 05, 75251, France
    Dev Biol 232:362-71. 2001
    ..Thus, whereas the final cell fate pattern of P11/12 is invariant, the developmental route leading to it is subject both to developmental indeterminacy and to evolutionary variations...
  32. ncbi request reprint Polymorphism and evolution of vulval precursor cell lineages within two nematode genera, Caenorhabditis and Oscheius
    M Delattre
    Institut Jacques Monod, CNRS, , Tour 43, 2 place Jussieu, 75251 Cedex 05, Paris, France
    Curr Biol 11:631-43. 2001
    ..CONCLUSIONS: Polymorphisms in vulval cell lineage are found within a given nematode species, and could be instrumental in explaining evolutionary variations between closely related species...
  33. ncbi request reprint Microevolutionary studies in nematodes: a beginning
    M Delattre
    Institut Jacques Monod, CNRS, , Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France
    Bioessays 23:807-19. 2001
    ..These studies have revealed that evolutionary variations between sister species affect those characters that show phenotypic developmental variants, that are mutable and that are polymorphic within species...
  34. doi request reprint The evolutionary context of robust and redundant cell biological mechanisms
    Marie Delattre
    Institut Jacques Monod, CNRS University of Paris 7 and 6, Paris, France
    Bioessays 31:537-45. 2009
    ..We present examples of cell biological processes, such as centrosome separation in prophase, spindle formation or cleavage furrow positioning, that support the first proposition. We propose experimental tests of these hypotheses...