Research Topics
| Najiba Fekih-MrissaSummaryCountry: France Publications
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Detail Information
Publications
Role of methylenetetrahydrofolate reductase A1298C polymorphism in cerebral venous thrombosisNajiba Fekih-Mrissa
Laboratory of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia
Blood Coagul Fibrinolysis 24:118-9. 2013..To our knowledge, there are no previous reports assessing the correlation between the MTHFR A1298C variant and CVT. Large study populations would be required to understand the contribution of this marker in the risk of CVT...
Association of HLA-DR/DQ polymorphism with myasthenia gravis in Tunisian patientsNajiba Fekih-Mrissa
Laboratory of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia
Clin Neurol Neurosurg 115:32-6. 2013..MG has been shown to be associated with many human leukocyte antigens (HLA) in different populations. The aim of this study was to investigate the probable association between HLA-DR/DQ alleles and MG in Tunisian patients...
Role of thrombophilia in vascular access thrombosis among chronic hemodialysis patients in TunisiaNajiba Fekih-Mrissa
Laboratory of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia
Ther Apher Dial 15:40-3. 2011..005). Our data demonstrated a significantly increased risk of vascular access thrombosis in carriers of the C677T methylene tetrahydrofolate reductase mutation...
Thrombophilic disorders: a real threat to patients with end-stage renal disease on hemodialysis and at the time of renal transplantationSarra Klai
Unit of Molecular Biology, Department of Hematology, Military Hospital of Tunis, Tunis, Tunisia
Blood Coagul Fibrinolysis 23:406-10. 2012..These results will serve as a basis for anticoagulant prophylaxis aimed at preventing kidney rejection and renal allograft thrombosis...
Maternal cerebral venous thrombosis, uncommon but serious disorder, pathologic predictors and contribution of prothrombotic abnormalitiesSarra Klai
Department of Hematology, Unit of Molecular Biology, Military Hospital, Tunis, Tunisia
Blood Coagul Fibrinolysis 24:269-72. 2013..Maternal CVT has been associated with factor V Leiden, the prothrombin G20210A mutation, protein C deficiency and hyperhomocysteinemia. We also speculate that non-O blood groups and preeclampsia could be independent risk factors for CVT...
Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathiesSarra Klai
Laboratory of Molecular Biology, Department of Hematology, Rabta University Hospital, Tunis, Tunisia
Blood Coagul Fibrinolysis 22:374-8. 2011..The MTHFR A1298C mutation also had a positive impact on elevated homocysteine levels. The lack of association between the MTHFR C677T polymorphism and pregnancy morbidities needs further studies...
Effects of prothrombotic markers and non-O blood group in maternal venous thromboembolism during pregnancy and postpartumSarra Klai
Unit of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia
Blood Coagul Fibrinolysis 23:649-52. 2012..The non-O blood group could also have an important influence, especially when concomitant with another prothrombotic risk factor mainly pregnancy and thrombophilia...
Inherited thrombophilia-related complications in the treatment of a biatrial thrombusIssam Jalouli
Department of Anesthesia and Intensive Care, Military Hospital of Tunisia, Tunis, Tunisia
Blood Coagul Fibrinolysis 24:205-7. 2013..The combination of these thrombophilic factors can probably explain the poor anticoagulant response, embolic events, and the failure of resolution of the biatrial masses...
Lack of association between factor V Leiden and prothrombin G20210A polymorphisms in Tunisian subjects with a history of myocardial infarctionDhouha Berredjeb Ben Slama
Laboratory of Molecular Biology, Department of Hematology, Military Hospital of Tunis, Tunis, Tunisia
Cardiovasc Pathol 22:39-41. 2013..Myocardial infarction is a multifactorial disease. It is provoked by occlusions in the coronary arteries resulting from exposure to multiple risk factors...
The status of thrombophilic defects and non-O blood group as risk factors for gestational vascular complications among Tunisian womenSarra Klai
Laboratory of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia
Acta Haematol 125:115-20. 2011..Our objectives were to assess inherited thrombophilia and non-O blood group for the risk of gestational vascular complications among the Tunisian population...
