Research Topics
| A FayeSummaryCountry: France Publications
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Publications
Early versus deferred antiretroviral multidrug therapy in infants infected with HIV type 1Albert Faye
Pediatrie Generale, hôpital R Debré, Paris, France
Clin Infect Dis 39:1692-8. 2004..The clinical impact of early antiretroviral multidrug therapy on the risk of early-onset severe human immunodeficiency virus (HIV) disease has not been evaluated on a large scale...
[New challenges in therapeutic management of human immunodeficiency virus-infected children]A Faye
Service de pédiatrie générale de l hôpital Robert Debré, 48, boulevard Serurier, 75019 Paris, France
Arch Pediatr 14:212-8. 2007..Finally, universal access to antiretroviral drugs in children, particularly in developing countries is the major actual and future challenge...
Chimaeric anti-CD20 monoclonal antibody (rituximab) in post-transplant B-lymphoproliferative disorder following stem cell transplantation in childrenA Faye
Service d Hémato immunologie, Hopital Robert Debre, Paris, France
Br J Haematol 115:112-8. 2001..Lack of rapid response should lead to intensification of PTLD treatment. Pre-emptive treatment should be considered and evaluated in further longitudinal multicentre studies...
Early multitherapy including a protease inhibitor for human immunodeficiency virus type 1-infected infantsAlbert Faye
Service d Hémato immunologie, Hĵpital R Debré, Paris, France
Pediatr Infect Dis J 21:518-25. 2002..To assess tolerance and efficacy of early multitherapy including a protease inhibitor for infants perinatally infected with HIV...
Post-transplant lymphoproliferative disorder in children: incidence, prognosis, and treatment optionsAlbert Faye
Service d Hémato immunologie, Hopital Robert Debre, Paris, France
Paediatr Drugs 7:55-65. 2005..These therapeutic approaches need to be further evaluated, especially in the context of pre-emptive strategies adapted to predictive markers of EBV-induced PTLD...
[Meningococcal disease due to Neisseria meningitidis serogroup W135 in children. Clinical aspects and outcome]Albert Faye
Service de Pediatrie Generale, Hôpital Robert Debrxé, Paris
Presse Med 33:654-7. 2004..Meningococcal disease due to Neisseria meningitidis of serogroup W135 (N. meningitidis W135) is increasing in France. Clinical and outcome data concerning these infections in children are scarce...
Clinical features and outcome of pediatric Neisseria meningitidis serogroup W135 infection: a report of 5 casesAlbert Faye
Service de Pediatrie Generale, Hopital Robert Debre, Paris, France
Clin Infect Dis 38:1635-7. 2004..Four of 5 isolates belonged to the clonal complex 37. The important risk of extrameningeal complications must be borne in mind when treating children with N. meningitidis W135 infection...
Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcomeConstance Delaugerre
EA 3620 MRT, Descartes University, Paris, France
Retrovirology 6:85. 2009..Primary-HIV-1-infection in newborns that occurs under antiretroviral prophylaxis that is a high risk of drug-resistance acquisition. We examine the frequency and the mechanisms of resistance acquisition at the time of infection in newborns...
[Evaluation of pre-travel prevention, except vaccination, in children returning from Africa with fever]E Seror
Service d Hématologie Pédiatrique, Hopital Robert Debre, Université Denis Diderot Paris, Assistance Publique Hopitaux de Paris, France
Arch Pediatr 18:1271-7. 2011..Evaluating the frequency and modalities of transmissible infection prevention counseling in children before a stay in tropical or subtropical areas...
[Clinical aspects and outcome of meningococcal disease due to Neisseria meningitidis of serogroup W135 in 5 children]A Faye
Service de Pediatrie Generale, Hopital Robert Debre, Assistance Publique Hopitaux de Paris, 48, boulevard Serurier, 75019 Paris, France
Arch Pediatr 12:291-4. 2005..In N. meningitidis W135 infections a careful clinical evaluation of potential extra-meningeal complications and a long term follow up of children are needed...
Characterization of the main placental cytokine profiles from HIV-1-infected pregnant women treated with anti-retroviral drugs in FranceA Faye
Unité de Régulation des Infections Rétrovirales, Institut Pasteur, Paris, France, and INSERM U782, Clamart, France
Clin Exp Immunol 149:430-9. 2007..These results highlight the potential impact of HIV-1 and of the anti-retroviral treatments on the placental cytokines pattern, independently of their anti-viral activity...
Prevention of mother-to-child HIV transmission: similar access for sub-Sahara African immigrants and for French women?Carine Jasseron
INSERM Unit 822, Le Kremlin Bicetre, Paris, France
AIDS 22:1503-11. 2008..To investigate whether mother-to-child transmission (MTCT) management and rate differed between African immigrants and French-born women delivering in France...
Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal CohortLaurent Mandelbrot
Assistance Publique Hopitaux de Paris AP HP, Service de Gynecologie Obstetrique, Hopital Louis Mourier, Colombes, and Université Paris 7 Diderot, Paris, France
Am J Obstet Gynecol 200:160.e1-9. 2009..The objective of the study was to investigate whether performing an amniocentesis increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 (MTCT)...
[Neonatal exposure to active pulmonary tuberculosis in a maternity ward: screening and clinical course of a cohort of exposed infants]A Perry
Service de Pediatrie Generale, Hopital Robert Debre, Assistance Publique des Hopitaux de Paris, 48 Boulevard Serurier, Paris, France
Arch Pediatr 19:396-403. 2012..Few data are available on the impact of a tuberculosis exposure on newborns in a maternity ward...
Early diagnosis of adenovirus infection and treatment with cidofovir after bone marrow transplantation in childrenF Legrand
, , Paris, France
Bone Marrow Transplant 27:621-6. 2001..Further studies in immunocompromised patients will be needed to extend these promising results concerning the role of cidofovir in adenovirus infection...
Invasive group A streptococcal infection in children: clinical manifestations and molecular characterization in a French pediatric tertiary care centerS Henriet
Assistance Publique des Hopitaux de Paris, Pediatrie Generale, Pôle de Pédiatrie Aigue et Médecine Interne, Hopital Robert Debre, Paris, France
Eur J Clin Microbiol Infect Dis 29:341-6. 2010..Further larger international pediatric studies, including host immunity evaluation, are needed in order to better assess the pathogenesis of GAS infection in children...
Anal sphincter response to distensionM Bouchoucha
Laboratoire de Physiologie Digestive, Hopital Broussais, 96 rue Didot, 75014 Paris, France
Int J Colorectal Dis 16:119-25. 2001..The response of the anal sphincter to distension is a simple test, which provides functional information on the behavior of the anal sphincteric zone...
Compartmentalised inducible nitric-oxide synthase activity in septic shockD Annane
Service de Reanimation Medicale, Hopital Raymond Poincare, Assistance Publique Hopitaux de Paris, Faculte de Medecine, France
Lancet 355:1143-8. 2000..Previous experimental studies support a role for inducible nitric-oxide synthase (iNOS) in the pathogenesis of severe sepsis. The aim of the study was to characterise iNOS activity in different tissues in patients with septic shock...
Pharmacokinetics of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1Catherine Litalien
Department of Pediatric Pharmacology and Pharmacogenetics, , Paris, France
Pediatr Infect Dis J 22:48-55. 2003..The mechanisms underlying such differences may involve higher first past metabolism and/or drug interactions or might be related to feeding conditions...
[Acute bacterial parotitis in infants under 3 months of age: a retrospective study in a pediatric tertiary care center]J Makhoul
Service pédiatrie générale, Pôle de Pédiatrie Aigue et Médecine Interne, Hopital Robert Debre, Paris, France
Arch Pediatr 18:1284-9. 2011..Acute bacterial parotitis is a rare infectious disease in infants under 3 months of age...
Association of prenatal and postnatal exposure to lopinavir-ritonavir and adrenal dysfunction among uninfected infants of HIV-infected mothersAlbane Simon
Unité d Endocrinologie Pédiatrique, Hopital Necker Enfants Malades, Assistance Publique Hopitaux de Paris, Paris, France
JAMA 306:70-8. 2011..A warning about its tolerance in premature newborns was recently released, and transient elevation of 17-hydroxyprogesterone (17OHP) was noted in 2 newborns treated with lopinavir-ritonavir in France...
Mother-to-child transmission of HIV-2 infection from 1986 to 2007 in the ANRS French Perinatal Cohort EPF-CO1M Burgard
Virology Laboratory, Hospital Necker, Assistance Publique Hopitaux de Paris, Paris, France
Clin Infect Dis 51:833-43. 2010..Methods: Pregnant women monoinfected with HIV-2 or HIV-1 and their infants enrolled in the prospective, national, multicenter French Perinatal Cohort between 1986 and 2007...
[Tolerance and efficacy of atovaquone-proguanil for the treatment of paediatric imported Plasmodium falciparum malaria in France: clinical practice in a university hospital in Paris]R Blondé
Service de Pediatrie Generale, Hopital Robert Debre, 48, boulevard Serurier, 75019 Paris, France
Arch Pediatr 15:245-52. 2008..falciparum malaria in adults. Few paediatric studies have evaluated atovaquone-proguanil in children for uncomplicated malaria in endemic area, but no study have evaluated this treatment for imported malaria...
Impact of implementing French antibiotic guidelines for acute respiratory-tract infections in a paediatric emergency department, 2005-2009F Angoulvant
Service d accueil des urgences pédiatriques, Hopital Robert Debre, Assistance Publique Hôpitaux de Paris and Université Paris 7 Denis Diderot, 48 Boulevard Serurier, 75019, Paris, France
Eur J Clin Microbiol Infect Dis 31:1295-303. 2012..French antibiotic guidelines led to significant decreases in antibiotic prescription for ARTI in our paediatric emergency department...
Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infectionA Gueye
, Institut Pasteur, Paris, France
J Med Primatol 33:83-97. 2004..The latter, despite showing marked regional variations, most likely contributes significantly to the high levels of viremia observed during SIVagm infection...
Immune reconstitution after haematopoietic transplantation with two different doses of pre-graft antithymocyte globulinM Duval
, , Paris, France
Bone Marrow Transplant 30:421-6. 2002..009). Although obtained from a limited number of patients, our data suggest that a higher pre-graft dose of antithymocyte globulin may negatively influence immune reconstitution...
Clinical outcome in children with chronic recurrent multifocal osteomyelitisC Catalano-Pons
Service de Pediatrie Generale, Centre hospitalier d Avignon, 305, rue Raoul Follereau, 84902 Avignon cedex 9, France
Rheumatology (Oxford) 47:1397-9. 2008..To determine the clinical outcome of children with chronic recurrent multifocal osteomyelitis (CRMO)...
Real-time PCR measurement of persistence of Bordetella pertussis DNA in nasopharyngeal secretions during antibiotic treatment of young children with pertussisPhilippe Bidet
Service de Microbiologie, Hopital Robert Debre, 48 Boulevard Serurier, Paris 75395 cedex 19, France
J Clin Microbiol 46:3636-8. 2008..86 to 3.68 cycles per day). Real-time PCR can thus be used to diagnose pertussis in young children for up to 3 weeks after treatment initiation. Its potential value for assessing the treatment outcome remains to be determined...
[Chronic otitis and hearing loss revealing a disseminated tuberculosis in a child]H See
, , , 48, , 75019 Paris, France
Arch Pediatr 13:1233-5. 2006..CONCLUSION: Middle ear tuberculosis should be suspected in patients with chronic otitis and risk factors of tuberculosis. A disseminated tuberculosis should be investigated and an early treatment is necessary to prevent hearing loss...
[Pilot study about pharmaceutical care implantation in a general paediatric unit in a French hospital. France-Québec collaboration and comparison]S Prot-Labarthe
Assistance Publique Hopitaux de Paris, Hopital Robert Debre, département de pharmacie et centre pluridisciplinaire de dosage des médicaments, Universite Paris V, 48 Boulevard Serurier, 75019 Paris, France
Arch Pediatr 14:345-53. 2007..STATE OF THE PROBLEM AND OBJECTIVES: French pharmacists are quasi absent from hospital wards. Our objective was to describe the implantation of pharmaceutical care in a patient unit of a French paediatric hospital...
Different segmental transit times in patients with irritable bowel syndrome and "normal" colonic transit time: is there a correlation with symptoms?M Bouchoucha
Digestive Physiology Laboratory, Broussais Hospital University of Paris V, 96 rue Didot, 75014, Paris, France
Tech Coloproctol 10:287-96. 2006..The goal of this study was to investigate whether the IBS symptoms, as defined in the Rome II criteria, correspond to objective physiological parameters, i.e. CCTs...
Uncomplicated outcome after an accidental overdose of nevirapine in a newbornJean François Brasme
Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Pediatric Intensive Care Unit, 48, boulevard Serurier, 75019 Paris, France
Eur J Pediatr 167:689-90. 2008..Despite the good evolution of this massive overdose, physicians should be aware of confusion risks between some antiretroviral drugs...
Late postnatal HIV infection in children born to HIV-1-infected mothers in a high-income countryPierre Frange
Unite d immunologie, Hématologie et Rhumatologie pédiatriques, Hopital Necker, Paris, France
AIDS 24:1771-6. 2010..To evaluate the risk of late postnatal HIV-1 infection in nonbreastfed children enrolled in the French ANRS Cohort CO01 (EPF)...
Molecular diagnosis of Saksenaea vasiformis cutaneous infection after scorpion sting in an immunocompetent adolescentPauline Lechevalier
AP HP, Hopital Robert Debre, Service de Pediatrie Generale, Université Paris Diderot Paris VII, Paris, France
J Clin Microbiol 46:3169-72. 2008..Saksenaea vasiformis was identified by PCR amplification and sequencing of the fungal DNA on a cutaneous biopsy. Successful treatment was obtained by surgery and liposomal amphotericin B...
Longitudinal evaluation and risk factors of lipodystrophy and associated metabolic changes in HIV-infected childrenMarta Beregszaszi
INSERM Unit 690, , Paris, France
J Acquir Immune Defic Syndr 40:161-8. 2005..Once developed, lipodystrophy and metabolic changes seem to be extremely stable with time...
Bilateral adrenal neuroblastoma and nephroblastoma occurring synchronously in a child with Fanconi's anemia and VACTERL syndromeDominique Berrebi
Services d'Anatomie et de Cytologie pathologiques et EA3102, , 75019 Paris, France
J Pediatr Surg 41:e11-4. 2006..Further studies are necessary to test if STI-571 treatment could be efficient in such patients with pediatric tumors...
Long-term nonprogression of HIV infection in children: evaluation of the ANRS prospective French Pediatric CohortJosiane Warszawski
Institut National de la Santé et de la Recherche Medicale U822, France
Clin Infect Dis 45:785-94. 2007..Our objective was to estimate the proportion of children who developed neither symptoms nor major immunological perturbations to the age of > or = 10 years in a prospective cohort of infected children who had been observed since birth...
Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal CohortJosiane Warszawski
INSERM, U822, IFR 60, Le Kremlin Bicetre, France
AIDS 22:289-99. 2008..To identify factors associated with mother-to-child HIV-1 transmission (MTCT) from mothers receiving antenatal antiretroviral therapy...
Bayesian parameter estimates of nelfinavir and its active metabolite, hydroxy-tert-butylamide, in infants perinatally infected with human immunodeficiency virus type 1Salomé Payen
Laboratoire de Pharmacocinetique Clinique, Faculte de Pharmacie, BP 14491, 34093 Montpellier Cedex 5, France
Antimicrob Agents Chemother 49:525-35. 2005....
Efficacy, safety and tolerability of tipranavir coadministered with ritonavir in HIV-1-infected children and adolescentsJuan C Salazar
Connecticut Children s Medical Center, University of Connecticut School of Medicine, Hartford, Connecticut 06106, USA
AIDS 22:1789-98. 2008..To evaluate the efficacy, safety and tolerability of ritonavir-boosted tipranavir (TPV/r) in HIV-1-infected pediatric patients...
Twin pregnancy as a risk factor for mother-to-child transmission of HIV-1: trends over 20 yearsClaudia Palladino Sili Scavalli
INSERM, U822, IFR69, Le Kremlin Bicetre, France
AIDS 21:993-1002. 2007..We investigated whether twin pregnancies were at increased risk of mother-to-child HIV-1 transmission (MTCT), in comparison with singletons...
Impact of the placental cytokine-chemokine balance on regulation of cell-cell contact-induced human immunodeficiency virus type 1 translocation across a trophoblastic barrier in vitroMuriel Derrien
, , Institut Pasteur, 25, rue du Dr. Roux 75724 Paris Cedex 15 France
J Virol 79:12304-10. 2005..This could explain the presence of viral sequences in trophoblasts in all placentae of HIV-1-infected women...
Recommendations for clinical practice. Management and prevention of imported Plasmodium falciparum malaria. (Revision 2007 of the 1999 Consensus conference). Short textJean-Paul Stahl
Med Mal Infect 38:54-67, 39-53. 2008
