Research Topics
| D FargeSummaryCountry: France Publications
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Detail Information
Publications
[Stem cell transplantation in autoimmune diseases]L Florea
Rev Med Interne 29:80-3. 2008
Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT/EULAR RegistryD Farge
St Louis Hospital, Paris, France
Ann Rheum Dis 63:974-81. 2004..This EBMT/EULAR report describes the longer outcome of patients originally described in addition to newly recruited cases...
[Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?]J Larghero
Unité de Thérapie Cellulaire, Hopital Saint Louis, AP HP, Paris, France
Rev Med Interne 30:287-99. 2009..Phase I-II studies are in progress in various countries to investigate the potential benefit from MSC due to their immunosuppressive properties, as an adjunctive therapy for severe refractory autoimmune disease...
[Follow-up with the assistance of TB-info software of 208 tuberculosis patients who were treated in 2004]A Bourgarit
Hopital Saint Louis, Paris, France
Rev Med Interne 30:841-6. 2009..The impact of the TB-info software was assessed on the care of patients treated with antituberculosis regimen (ATT)...
Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetesL Vija
INSERM U697, Paris, France
Diabetes Metab 35:85-93. 2009..In this review, we provide a brief characterization of MSC immunomodulatory effects, and present the current experimental evidence for the potential therapeutic efficacy of MSC transplantation in diabetes...
Phenotypical and functional characteristics of in vitro expanded bone marrow mesenchymal stem cells from patients with systemic sclerosisJ Larghero
Cell Therapy Unit, Assistance Publique Hopitaux de Paris, Saint Louis Hospital, Paris, France
Ann Rheum Dis 67:443-9. 2008..Mesenchymal stem cells (MSCs) have a potential immunomodulatory role in autoimmune disease; however, the qualitative properties and haematopoietic support capacity of MSCs derived from patients with autoimmune disease is unclear...
Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group DatabaseChristian Pagnoux
Universite Paris Descartes, Hopital Cochin, Assistance Publique Hopitaux de Paris, Paris, France
Arthritis Rheum 62:616-26. 2010..This study was undertaken to describe the main characteristics of and long-term outcomes in patients with well-characterized PAN diagnoses...
Skin involvement in scleroderma--where histological and clinical scores meetF Verrecchia
INSERM U697, Paris, France
Rheumatology (Oxford) 46:833-41. 2007....
[Cytokines in systemic sclerosis]J Baraut
hôpital Saint Louis pavillon Bazin, Paris, France
Pathol Biol (Paris) 60:127-39. 2012..The restoration of the Th1/Th2/Th17/Treg balance will contribute to the effectiveness of treatment and the use of cytokine modulators may therefore be considered in developing new therapeutic approaches...
Diagnostic value of a nested polymerase chain reaction assay on peripheral blood mononuclear cells from patients with pulmonary and extra-pulmonary tuberculosisS Honore
Service de Microbiologie, Hopital Saint Louis, Paris, France
Int J Tuberc Lung Dis 5:754-62. 2001..However, further studies are needed to confirm this technique as an alternative test for the diagnosis of paucibacillary forms of tuberculosis...
European League Against Rheumatism (EULAR) Scleroderma Trial and Research group (EUSTAR) recommendations for the treatment of systemic sclerosis: methods of elaboration and results of systematic literature researchJ Avouac
Rheumatology A Department, RDU, Paris, France
Ann Rheum Dis 68:629-34. 2009..In particular, the results of a web-based Delphi exercise aimed at selection of research questions and evidence from systematic literature research, as parts of the development of these recommendations, are presented in detail...
Azathioprine or methotrexate maintenance for ANCA-associated vasculitisChristian Pagnoux
Universite Paris Descartes, Hopital Cochin, Assistance Publique Hopitaux de Paris, Paris, France
N Engl J Med 359:2790-803. 2008..However, azathioprine and methotrexate have not been compared with regard to safety and efficacy...
Tuberculosis in European cities: establishment of a patient monitoring system over 10 years in Paris, FranceD Farge
Service de médecine interne et pathologie vasculaire, Hopital Saint Louis, Paris, France
Int J Tuberc Lung Dis 11:992-8. 2007..France has been unable to report on treatment outcomes until now, and it is not known whether the World Health Organization (WHO) target cure rate of 85% has been met...
[Cardiopulmonary function before and after cyclophosphamide treatment in severe systemic sclerosis: comparison of monthly intravenous bolus and autologous haematopoietic stem cell transplantation]C Toledano
Service de Medecine Interne, Hopital Saint Louis, Paris, France
Rev Med Interne 26:444-52. 2005..Cyclophosphamide potential cardiotoxicity in this setting has been questioned...
[All colors on a black skin!]A Gallet
, , Paris, France
Rev Med Interne 26:S299-301. 2005
[Therapeutic intensification and autologous stem cell transplantation in autoimmune diseases]Z Marjanovic
, Service de Greffe de Moelle, , 1, avenue Claude Vellefaux, 75010 Paris, France
Presse Med 34:311-8. 2005..A STUDY PROJECT IS PLANNED FOR MULTIPLE SCLEROSIS (Astims, Autologous Stem cell Transplantation International Multiple Sclerosis)...
[Quality of life assessment with the MOS-SF36 in patients with systemic sclerosis]C Georges
Service de Medecine Interne, Hopital Saint Louis, 1, avenue Claude Vellefaux, 75475 Paris 10, France
Rev Med Interne 25:16-21. 2004....
Validation of French version of the Scleroderma Health Assessment Questionnaire (SSc HAQ)C Georges
AP HP, Internal Medicine, Saint Louis Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
Clin Rheumatol 24:3-10. 2005..In addition, we suggest the use of a new outcome measure, the SSc HAQ score, to assess this systemic disease more accurately...
Autologous Stem cell Transplantation International Scleroderma (ASTIS) trial: hope on the horizon for patients with severe systemic sclerosisJ M van Laar
Ann Rheum Dis 64:1515. 2005
[Bone marrow transplantation in the treatment of autoimmune disease]D Farge
, , INSERM U697, 1 avenue Claude-Vellefaux, 75010 Paris, France
Rev Med Interne 28:S285-7. 2007
Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosisM C Vonk
Department of Rheumatology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Ann Rheum Dis 67:98-104. 2008..This study reports the effects on survival, skin and major organ function of HSCT in patients with severe diffuse cutaneous SSc...
Impact of pain in health related quality of life of patients with systemic sclerosisC Georges
Internal Medicine Department, Saint Louis Hospital, Service de Medecine Interne, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
Rheumatology (Oxford) 45:1298-302. 2006..The aim of the study is as to evaluate the quality of life (QoL) in patients with either diffuse or limited SSc, and to examine the impact of pain on the QoL scores...
Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin diseaseM Binks
Royal Free Hospital, London
Ann Rheum Dis 60:577-84. 2001..If future trials incorporate inclusion and exclusion criteria based on this preliminary experience, the predicted procedure related mortality should be around 10%...
