Research Topics
| L FardetSummaryCountry: France Publications
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Publications
[In-hospital mortality and stay duration of internal medicine patients: prognosis value of biochemical markers commonly performed on admission]A Kettaneh
Service de Medecine Interne, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Paris, 75012 Paris, France
Rev Med Interne 28:443-9. 2007..We have examined retrospectively the relationship between inhospital mortality or stay duration and several biochemical markers commonly performed on admission in internal medicine patients...
A retrospective analysis of thalidomide therapy in non-HIV-related Kaposi's sarcomaLaurence Fardet
Department of Dermatology, Hospital Saint Louis, Paris, France
Dermatology 215:202-5. 2007..Thalidomide has antiangiogenic and immunomodulatory properties and has recently been used in the management of human malignancies. Several studies have suggested its interest for treating AIDS-related Kaposi's sarcoma...
Digital photography as an operational tool for assessing corticosteroid-induced lipodystrophyLaurence Fardet
Department of Internal Medicine, Hopital Saint Antoine, 184 rue du Fbg Saint Antoine, 75012 Paris, France
Eur J Intern Med 19:340-4. 2008..Corticosteroid-induced lipodystrophy (CIL) is exclusively diagnosed in a subjective manner...
[Internal medicine physicians' perception of frequency and impact of corticosteroid-induced adverse events]L Fardet
Service de Medecine Interne, Hopital Saint Antoine, AP HP, 184, rue du Faubourgh Saint Antoine, 75012 Paris, France
Rev Med Interne 30:113-8. 2009..Whereas internal medicine physicians frequently prescribe systemic corticosteroids, it is unknown if they assess adequately the frequency and the discomfort caused by corticosteroid-induced adverse events...
[Short-term effect of dietary-sodium intake on arterial blood pressure of patients treated with systemic corticosteroids: a prospective, randomised, crossover study]L Fardet
Service de Medecine Interne, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
Rev Med Interne 30:741-6. 2009..It is unknown if the level of dietary-sodium intake influences blood pressure in patients receiving systemic corticosteroids...
Severe neuropsychiatric outcomes following discontinuation of long-term glucocorticoid therapy: a cohort studyLaurence Fardet
Service de Medecine Interne, Hopital Saint Antoine, 184 rue du Fbg Saint Antoine, 75012 Paris, France
J Clin Psychiatry 74:e281-6. 2013..These patients may develop neuropsychiatric disorders when the drug is discontinued...
[Metabolic and cardiovascular adverse events of systemic glucocorticoid therapy]L Fardet
INSERM UMR S 938, Service de Medecine Interne, Faculte de Medecine, Université Pierre et Marie Curie UPMC Paris 6, Hopital Saint Antoine, AP HP, 184, rue du Faubourg Saint Antoine, 75012 Paris, France Electronic address
Rev Med Interne 34:303-9. 2013..Some of these questions can be answered by looking at available data in patients with endogenous hypercorticism...
Risk of cardiovascular events in people prescribed glucocorticoids with iatrogenic Cushing's syndrome: cohort studyLaurence Fardet
MRC General Practice Research Framework, University College London Medical School, London, UK
BMJ 345:e4928. 2012..To investigate whether there is an increased risk of cardiovascular events in people who exhibit iatrogenic Cushing's syndrome during treatment with glucocorticoids...
Suicidal behavior and severe neuropsychiatric disorders following glucocorticoid therapy in primary careLaurence Fardet
Medical Research Council General Practice Research Framework, London, UK
Am J Psychiatry 169:491-7. 2012..The authors assessed the incidence rates of depression, mania, delirium, panic disorder, and suicidal behaviors in patients treated with glucocorticoids in primary care settings and the risk factors for developing these outcomes...
Incidence and risk factors for corticosteroid-induced lipodystrophy: a prospective studyLaurence Fardet
Department of Internal Medicine, Hopital Saint Antoine, Paris, France
J Am Acad Dermatol 57:604-9. 2007..Very few studies have focused on fat redistribution induced by corticosteroids...
Corticosteroid-induced adverse events in adults: frequency, screening and preventionLaurence Fardet
Department of Internal Medicine, Hopital Saint Antoine, Paris, France
Drug Saf 30:861-81. 2007..g. lipodystrophy, dyslipidaemia). Our intent is to present to practitioners data that can be used in a practical way to both screen and prevent most of the adverse events observed during systemic corticosteroid therapy...
[Natural history of corticosteroid-induced lipodystrophy: a prospective follow-up of 37 patients]L Fardet
Service de médecine interne Horloge II, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
Rev Med Interne 28:825-31. 2007..No data is available about the natural history of the corticosteroid-induced lipodystrophy. The purpose of this study is to describe the natural history of corticosteroid-induced lipodystrophy in a selected and homogenous population...
[Long-term systemic corticosteroid-therapy associated measures: description of the French internal medicine physicians' practices]L Fardet
Service de Medecine Interne, Hopital Saint Antoine, AP HP, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
Rev Med Interne 29:975-80. 2008..The aim of this study was to assess the internal medicine physicians' practices regarding the prescription of long-term corticosteroid therapy...
Corticosteroid-induced clinical adverse events: frequency, risk factors and patient's opinionL Fardet
Department of Internal Medicine, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
Br J Dermatol 157:142-8. 2007..More than 50 years after the introduction of corticosteroids, few studies have focused on corticosteroid-induced adverse events after long-term systemic therapy...
Corticosteroid-induced lipodystrophy is associated with features of the metabolic syndromeL Fardet
Departement de Medecine Interne, Hopital Saint Antoine, 184 rue du Fbg Saint Antoine, 75012 Paris, France
Rheumatology (Oxford) 46:1102-6. 2007..Familial and HIV-associated lipodystrophies are associated with metabolic disorders and elevated blood pressure. Whether corticosteroid-induced lipodystrophy (CIL) is also associated with features of the metabolic syndrome is unknown...
[Systemic corticosteroid therapy: patients' adherence to dietary advice and relationship between food intake and corticosteroid-induced lipodystrophy]L Fardet
Service de Medecine Interne, Horloge 2, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
Rev Med Interne 28:284-8. 2007..No data is available about: 1) the adherence of corticosteroid-treated patients to dietary advice provided by physicians; 2) the relationship between food intake and the corticosteroid-induced lipodystrophy (CIL)...
Prevalence of long-term oral glucocorticoid prescriptions in the UK over the past 20 yearsLaurence Fardet
MRC General Practice Research Framework, University College London Medical School, Stephenson House, 158 160 North Gower Street, London NW1 2ND, UK
Rheumatology (Oxford) 50:1982-90. 2011..To assess trends in long-term (i.e. ≥3 months) oral glucocorticoid (GC) prescriptions over the past 20 years...
Infliximab for severe hidradenitis suppurativa: transient clinical efficacy in 7 consecutive patientsLaurence Fardet
Department of Dermatology, Hospital Saint Antoine, Paris, France
J Am Acad Dermatol 56:624-8. 2007..In the study presented here, we assessed the safety and efficacy of infliximab in a series of patients with severe HS...
[Description of oral glucocorticoid prescriptions in general population]L Fardet
Service de Medecine Interne, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
Rev Med Interne 32:594-9. 2011..Very little is known about oral glucocorticoids (GCs) prescriptions in general population...
Low glycosylated ferritin, a good marker for the diagnosis of hemophagocytic syndromeLaurence Fardet
Department of Internal Medicine, Hopital Saint Antoine, Paris, France
Arthritis Rheum 58:1521-7. 2008..We undertook this study to determine whether hemophagocytic syndrome outside the context of AOSD is also associated with a very low percentage of glycosylated ferritin...
[General practitioners' perception of the impact of corticosteroid-induced adverse events]A Perdoncini-Roux
Service de medecine interne Horloge 2, Hopital Saint Antoine, AP HP, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
Rev Epidemiol Sante Publique 57:93-7. 2009..General practitioners' perception of the discomfort their patients experience because of corticosteroid-induced adverse events is unknown...
[Patients' beliefs about long-term glucocorticoid therapy and their association to treatment adherence]L Zerah
Service de Medecine Interne, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
Rev Med Interne 33:300-4. 2012..In patients treated with systemic glucocorticoids (GCs), it is unknown if beliefs about the treatment are associated with level of reported adherence...
Impact of glucocorticoid-induced adverse events on adherence in patients receiving long-term systemic glucocorticoid therapyC Arena
INSERM, U707, Paris, France
Br J Dermatol 163:832-7. 2010..Factors influencing adherence to long-term (i.e. ≥ 3 months) systemic glucocorticoid therapy are poorly understood...
[Pulmonary embolism revealed by a seizure: a case report and literature review]M Lam
Service de Medecine Interne, Université Pierre et Marie Curie Paris, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, 184 rue du Faubourg Saint Antoine, Paris, France
Rev Med Interne 33:457-60. 2012..Pulmonary embolism is a frequent disorder with a diagnostic approach based on probability estimation. Nevertheless, in some cases, prognosis may be impaired by delayed diagnosis resulting from atypical presenting manifestations...
[Münchausen syndrome with forgery on biologic results. A case report]F Thabuy
Service de Medecine Interne, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, 75012 Paris cedex, France
Rev Med Interne 29:924-8. 2008....
[Seizure-related purpura]A Angelergues
, , , , 184, rue du Faubourg-Saint-Antoine, 75571 Paris Cedex 12, France
Rev Med Interne 29:502-3. 2008
Idiopathic systemic capillary leak syndrome: cutaneous involvement can be misleadingL Fardet
Department of Dermatology, Centre Hospitalier Universitaire Saint-Louis, Paris, France
Dermatology 209:291-5. 2004..CONCLUSION: The above-mentioned cutaneous findings can be present during acute attacks of ISCLS. They seem specifically related to the ISCLS and not indicative of an underlying disease...
[A persistent dysphagia]C Wolfers
, , 184, rue du Faubourg-Saint-Antoine, 75571 Paris Cedex 12, France
Rev Med Interne 28:780-1. 2007
Localized scleroderma: a series of 52 patientsC Toledano
Department of Internal Medicine Centre Hospitalo Universitaire Saint Antoine, 75012 Paris, Assistance Publique Hopitaux de Paris, France
Eur J Intern Med 20:331-6. 2009..Whether each of these distinct types has a particular clinical course or is associated with some patient-related features is still unclear...
[Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome]G d'Ythurbide
Service de Medecine Interne, Universite Pierre et Marie Curie, 75012 Paris, France
Rev Med Interne 30:255-9. 2009..Hepatic involvement of this multi-systemic disorder can be confused with HELLP syndrome, occurring usually later in the course of pregnancy...
Factors associated with underlying malignancy in a retrospective cohort of 121 patients with dermatomyositisLaurence Fardet
Universite Paris 7, Diderot, Paris
Medicine (Baltimore) 88:91-7. 2009..33; 95% CI, 0.14-0.80). Taken together, these data may help physicians focus on a group of patients who might benefit from extensive evaluation for malignancy...
Reactive haemophagocytic syndrome in 58 HIV-1-infected patients: clinical features, underlying diseases and prognosisLaurence Fardet
Hopital Saint Antoine, France
AIDS 24:1299-306. 2010..To describe features of reactive haemophagocytic syndrome (RHS) in HIV-1-infected adult patients. To compare characteristics of patients with malignancy-associated RHS and infection-associated RHS...
Incidence, risk factors, and severity of herpesvirus infections in a cohort of 121 patients with primary dermatomyositis and dermatomyositis associated with a malignant neoplasmLaurence Fardet
Université Paris 7 Diderot and Department of Dermatology, Assistance Publique Hopitaux de Paris, Hopital Saint Louis, Paris, France
Arch Dermatol 145:889-93. 2009..Opportunistic infections have been reported in 15% to 21% of patients with inflammatory myositis. However, to our knowledge, no data are available regarding the incidence, risk factors, and severity of herpesvirus infections...
[A rare cause of diffuse osteosclerosis]K Dawidowicz
, , 184, rue du Faubourg-Saint-Antoine, 75571 Paris Cedex 12, France
Rev Med Interne 28:261-2. 2007
[Skin discoloration]I Ouzaid
, , APHP, , 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France
Rev Med Interne 27:787-8. 2006
Frequency, clinical features and prognosis of cutaneous manifestations in adult patients with reactive haemophagocytic syndromeL Fardet
Department of Dermatology, Hopital Saint Louis, Paris, France
Br J Dermatol 162:547-53. 2010..Cutaneous involvement has been reported in 30-40% of children with the familial form of haemophagocytic syndrome. However, few studies have focused on cutaneous manifestations in patients with reactive haemophagocytic syndrome (RHS)...
Devic's neuromyelitis optica: study of nine casesL Fardet
, , Centre Hospitalier Universitaire Saint Antoine, Paris, France
Acta Neurol Scand 108:193-200. 2003..The others showed evidence that another disease like MS was involved. We stress that inclusion and exclusion criteria have to be kept in mind to differentiate clearly DNMO from MS and other central nervous system white matter diseases...
[Perception of organ grafts by internists]L Fardet
, , 184, rue du Faubourg-Saint-Antoine 75571 Paris, France
Rev Med Interne 23:542-8. 2002..The inherent risk in this is to see this specialty gradually excluded from the care networks available to grafted patients...
[Description of French general practitioners' practices regarding long term systemic corticosteroid therapy-associated measures]Aurélie Perdoncini-Roux
AP HP, Service de Medecine Interne, Hopital Saint Antoine, 75012 Paris, France
Rev Prat 59:19-24. 2009..We assessed the French general practitioners'practices regarding the prescription of these measures...
Severe strongyloidiasis in corticosteroid-treated patients: case series and literature reviewLaurence Fardet
Hopital Saint Antoine, Internal Medicine, Parasitology and Intensive Care Department, 184 rue du Fbg Saint Antoine, 75012 Paris, France
J Infect 54:18-27. 2007..To describe the main features of severe strongyloidiasis in corticosteroid-treated patients..
The 2003 heat wave in France: hydratation status changes in older inpatientsAdrien Kettaneh
Department of Internal Medicine, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, 184 rue du Fbg Saint Antoine, 75571, Paris Cedex 12, France
Eur J Epidemiol 25:517-24. 2010..27) than in 2000-2002 (HR 1.64) or 2004-2006 (HR 1.77) (P = 0.04). So, since the 2003 heat wave, significant shifts in prevalence of intracellular hydration disorders indicate behavioral changes with positive impact on hydration status...
Mesenteric ischemia in giant cell arteritis: 6 cases and a systematic reviewPierre Sujobert
Department of Internal Medicine, Hopital Saint Antoine, Paris, France
J Rheumatol 34:1727-32. 2007..To report the main features of mesenteric ischemia related to giant cell arteritis (GCA)...

