Research Topics
Genomes and GenesSpecies | Jean Yves ExpositoSummaryCountry: France Publications
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Publications
Evolution of collagensJean Yves Exposito
Institut de Biologie et Chimie des Proteines, Universite Claude Bernard, Lyon, France
Anat Rec 268:302-16. 2002....
Tracing the evolution of vertebrate fibrillar collagens from an ancestral alpha chainJ Exposito
Institut de Biologie et Chimie des Proteines, CNRS, Unité Propre de Recherche 412, Universite Claude Bernard, 7 passage du Vercors, 69367 Cedex 07, Lyon, France
Matrix Biol 19:275-9. 2000....
Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to humanJean Yves Exposito
Institut de Biologie et Chimie des Protéines IBCP, 7 passage du Vercors, Lyon, F69367, France, CNRS, UMR 5086
J Biol Chem 283:28226-35. 2008..This observation is compatible with the suggested primordial function of type V/XI fibrillar collagens in the initiation of the formation of the collagen fibrils...
Tenascin-X increases the stiffness of collagen gels without affecting fibrillogenesisYoran Margaron
Institut de Biologie et Chimie des Proteines, IFR 128 Biosciences Lyon Gerland, CNRS UMR 5086, Universite de Lyon, 7 passage du Vercors, F 69367 Lyon Cedex 07, France
Biophys Chem 147:87-91. 2010....
A model of tenascin-X integration within the collagenous networkClaire Lethias
Institut de Biologie et Chimie des Proteines, IFR 128 Biosciences Lyon Gerland, CNRS UMR 5086, Universite de Lyon, 7 passage du Vercors, 69367 Lyon Cedex 07, France
FEBS Lett 580:6281-5. 2006..We thus suggest that tenascin-X, via trimerization and multiple interactions with components of collagenous fibrils, plays a crucial role in the organisation of extracellular matrices...
The fibrillar collagen familyJean Yves Exposito
, IFR 128 Biosciences Lyon Gerland, CNRS UMR 5086, , 7 passage du Vercors, F 69367 Lyon Cedex 07, France E Mails U V C G C L
Int J Mol Sci 11:407-26. 2010..We will also discuss some other aspects of fibrillar collagen evolution such as the development of the molecular mechanisms involved in the formation of procollagen molecules and of striated fibrils...
Isolation, characterization and biological evaluation of jellyfish collagen for use in biomedical applicationsSourour Addad
Universite Lyon 1, Univ Lyon, CNRS, FRE 3310, Dysfonctionnement de l Homéostasie Tissulaire et Ingénierie Thérapeutique, IBCP, 7 passage du Vercors, F 69367, France
Mar Drugs 9:967-83. 2011..Given the bioavailability of jellyfish collagen and its biological properties, this marine material is thus a good candidate for replacing bovine or human collagens in selected biomedical applications...
Insights into early extracellular matrix evolution: spongin short chain collagen-related proteins are homologous to basement membrane type IV collagens and form a novel family widely distributed in invertebratesAbdel Aouacheria
, UMR CNRS 5558, , Villeurbanne, France
Mol Biol Evol 23:2288-302. 2006..Considering the importance of collagens for animal structure and substratum attachment, both families may have played crucial roles in animal diversification...
Invertebrate data predict an early emergence of vertebrate fibrillar collagen clades and an anti-incest modelAbdel Aouacheria
, CNRS, , , , 7 passage du Vercors, 69367 Lyon Cedex 07, France
J Biol Chem 279:47711-9. 2004..Moreover, they indicate that all the key steps required for the formation of fibrils of variable structure and functionality arose step by step during invertebrate evolution...
Distinct maturations of N-propeptide domains in fibrillar procollagen molecules involved in the formation of heterotypic fibrils in adult sea urchin collagenous tissuesCaroline Cluzel
, CNRS, , , France
J Biol Chem 279:9811-7. 2004....
