N Enjolras

Summary

Country: France

Publications

  1. ncbi Two novel mutations in EGF-like domains of human factor IX dramatically impair intracellular processing and secretion
    N Enjolras
    Laboratoire d Hémobiologie EA 1508, Faculté de médecine RTH Laennec, Lyon, France
    J Thromb Haemost 2:1143-54. 2004
  2. ncbi A factor VIII minigene comprising the truncated intron I of factor IX highly improves the in vitro production of factor VIII
    J L Plantier
    INSERM U331, , Lyon, France
    Thromb Haemost 86:596-603. 2001
  3. ncbi The P-selectin cytoplasmic domain directs the cellular storage of a recombinant chimeric factor IX
    J L Plantier
    INSERM U331, Laboratoire d Hémobiologie Faculté de Médecine RTH, Laennec, Lyon, France
    J Thromb Haemost 1:292-9. 2003
  4. doi Activated factor X cleaves factor VIII at arginine 562, limiting its cofactor efficiency
    J L Plantier
    Laboratoire d hémobiologie EA4174, Faculté RTH Laennec, Universite de Lyon, Universite Lyon 1, Lyon, France
    J Thromb Haemost 8:286-93. 2010
  5. ncbi Expression of coagulation factor IX in a haematopoietic cell line
    M H Rodriguez
    INSERM U331, Laboratoire d Hemobiologie Faculté de Médecine RTH Laennec, Lyon, France
    Thromb Haemost 87:366-73. 2002

Collaborators

Detail Information

Publications5

  1. ncbi Two novel mutations in EGF-like domains of human factor IX dramatically impair intracellular processing and secretion
    N Enjolras
    Laboratoire d Hémobiologie EA 1508, Faculté de médecine RTH Laennec, Lyon, France
    J Thromb Haemost 2:1143-54. 2004
    ..These results strongly suggest that chaperone and lectin molecules act in concert to ensure both proper folding of FIXwt and the retention of mutant molecules...
  2. ncbi A factor VIII minigene comprising the truncated intron I of factor IX highly improves the in vitro production of factor VIII
    J L Plantier
    INSERM U331, , Lyon, France
    Thromb Haemost 86:596-603. 2001
    ..Therefore, the FVIII I1+13 minigene could represent a particular interest to produce recombinant FVIII in vitro as well as in the aim of gene therapy of haemophilia A...
  3. ncbi The P-selectin cytoplasmic domain directs the cellular storage of a recombinant chimeric factor IX
    J L Plantier
    INSERM U331, Laboratoire d Hémobiologie Faculté de Médecine RTH, Laennec, Lyon, France
    J Thromb Haemost 1:292-9. 2003
    ....
  4. doi Activated factor X cleaves factor VIII at arginine 562, limiting its cofactor efficiency
    J L Plantier
    Laboratoire d hémobiologie EA4174, Faculté RTH Laennec, Universite de Lyon, Universite Lyon 1, Lyon, France
    J Thromb Haemost 8:286-93. 2010
    ..Among the proteases that attack FVIII (activated factor X (FXa), activated protein C (APC) and plasmin), only APC cleaves within the FVIII A2 domain at R562 to fully abolish FVIII activity...
  5. ncbi Expression of coagulation factor IX in a haematopoietic cell line
    M H Rodriguez
    INSERM U331, Laboratoire d Hemobiologie Faculté de Médecine RTH Laennec, Lyon, France
    Thromb Haemost 87:366-73. 2002
    ..These data also demonstrate that hematopoietic cells may represent potential target cells in an approach to gene therapy of haemophilia B...