Shahin Emami

Summary

Country: France

Publications

  1. ncbi Trefoil factor family (TFF) peptides and cancer progression
    Shahin Emami
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Peptides 25:885-98. 2004
  2. ncbi Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells
    Sylvie Rodrigues
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, , 75571 Paris, France
    Oncogene 22:4488-97. 2003
  3. ncbi Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts
    Quang De Nguyen
    Institut National de la Sante et de la Recherche Medicale U673, Universite Pierre et Marie Curie Paris 6, Molecular and Clinical Oncology of Solid Tumors, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Mol Cancer Ther 5:2070-7. 2006
  4. ncbi G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells
    Karine Régnauld
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Oncogene 21:4020-31. 2002
  5. ncbi Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling
    Sylvie Rodrigues
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, , 75571 Paris Cedex 12, France
    FASEB J 17:7-16. 2003
  6. ncbi Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    Michèle Sabbah
    INSERM U673, Molecular and Clinical Oncology of Solid Tumors, Universite Pierre et Marie Curie Paris 6, Faculte de Medecine, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Drug Resist Updat 11:123-51. 2008
  7. ncbi Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor
    Jean Pierre Roperch
    Institut National de la Sante, Recherche Medicale U673 Molecular and Clinical Oncology of Solid Tumors, Universite Pierre et Marie Curie Paris 6, Hopital Saint Antoine, Paris, France
    Cancer Res 68:8231-9. 2008
  8. ncbi RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion
    Quang De Nguyen
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    FASEB J 16:565-76. 2002
  9. ncbi Pinworm and TNKS inhibitors, an eccentric duo to derail the oncogenic WNT pathway
    Radia Ouelaa-Benslama
    Inserm U938, Laboratory of Cancer Biology and Therapeutics, UMPC Paris 6, Saint Antoine Hospital, Kourisky building, 184, rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Clin Res Hepatol Gastroenterol 35:534-8. 2011
  10. ncbi Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion
    Severine Van Slambrouck
    Laboratory of Biochemical and Biomedical Research, Department of Chemistry, New Mexico Tech, Socorro, NM, USA
    Int J Oncol 31:1501-8. 2007

Collaborators

Detail Information

Publications10

  1. ncbi Trefoil factor family (TFF) peptides and cancer progression
    Shahin Emami
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Peptides 25:885-98. 2004
    ..As a consequence, the TFF signaling pathways may serve as potential targets in the control of chronic inflammation and progression of human solid tumors...
  2. ncbi Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells
    Sylvie Rodrigues
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, , 75571 Paris, France
    Oncogene 22:4488-97. 2003
    ..It is concluded that although pS2, SP and ITF belong to the same family of inflammation- and cancer-associated regulatory peptides, they do not control identical signaling networks...
  3. ncbi Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts
    Quang De Nguyen
    Institut National de la Sante et de la Recherche Medicale U673, Universite Pierre et Marie Curie Paris 6, Molecular and Clinical Oncology of Solid Tumors, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Mol Cancer Ther 5:2070-7. 2006
    ....
  4. ncbi G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells
    Karine Régnauld
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Oncogene 21:4020-31. 2002
    ..doi:10.1038/sj.onc.1205498..
  5. ncbi Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling
    Sylvie Rodrigues
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, , 75571 Paris Cedex 12, France
    FASEB J 17:7-16. 2003
    ....
  6. ncbi Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    Michèle Sabbah
    INSERM U673, Molecular and Clinical Oncology of Solid Tumors, Universite Pierre et Marie Curie Paris 6, Faculte de Medecine, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    Drug Resist Updat 11:123-51. 2008
    ..This goal can be accomplished using global screening of human clinical tumors by EMT-associated cDNA, proteome, miRome, and tissue arrays...
  7. ncbi Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor
    Jean Pierre Roperch
    Institut National de la Sante, Recherche Medicale U673 Molecular and Clinical Oncology of Solid Tumors, Universite Pierre et Marie Curie Paris 6, Hopital Saint Antoine, Paris, France
    Cancer Res 68:8231-9. 2008
    ..Collectively, our data reveal that the transcriptionally active TAp73alpha tumor suppressor is implicated in the apoptosis induced by netrin-1 in a p53-independent and DCC/ubiquitin-proteasome dependent manner...
  8. ncbi RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion
    Quang De Nguyen
    INSERM U482, Signal Transduction and Cellular Functions in Diabetes and Digestive Cancers, Hopital Saint Antoine, 75571 Paris Cedex 12, France
    FASEB J 16:565-76. 2002
    ..Nguyen, Q.-D., Faivre, S., Bruyneel, E., Rivat, C., Seto, M., Endo, T., Mareel, M., Emami, S., Gespach, C. RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion...
  9. ncbi Pinworm and TNKS inhibitors, an eccentric duo to derail the oncogenic WNT pathway
    Radia Ouelaa-Benslama
    Inserm U938, Laboratory of Cancer Biology and Therapeutics, UMPC Paris 6, Saint Antoine Hospital, Kourisky building, 184, rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Clin Res Hepatol Gastroenterol 35:534-8. 2011
    ..These could lead to the identification of new biomarkers and WNT-targeted inhibitors for the treatment of cancer...
  10. ncbi Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion
    Severine Van Slambrouck
    Laboratory of Biochemical and Biomedical Research, Department of Chemistry, New Mexico Tech, Socorro, NM, USA
    Int J Oncol 31:1501-8. 2007
    ..These findings support the notion that the alpha1-integrin- and src-dependent signalosome is a relevant therapeutic target against tumor progression in colon cancer patients...