Saadia Eddahibi

Summary

Country: France

Publications

  1. ncbi request reprint Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia
    Saadia Eddahibi
    INSERM U651, Departement de Physiologie, Hôpital H Mondor, AP HP, Creteil, France
    Circulation 113:1857-64. 2006
  2. pmc Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene
    Daniel Crona
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
    BMC Pulm Med 9:19. 2009
  3. ncbi request reprint Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension
    Elisabeth Marcos
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, Creteil, France
    Circ Res 94:1263-70. 2004
  4. ncbi request reprint Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease
    Saadia Eddahibi
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, AP HP, 94010 Creteil, France
    Circulation 108:1839-44. 2003
  5. ncbi request reprint Role of endothelium-derived CC chemokine ligand 2 in idiopathic pulmonary arterial hypertension
    Olivier Sanchez
    INSERM U841 and Département de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, AP HP, Creteil, France
    Am J Respir Crit Care Med 176:1041-7. 2007
  6. pmc Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice
    William Raoul
    Unité INSERM TGU841 Université Paris XII, Creteil, France
    Respir Res 8:8. 2007
  7. ncbi request reprint Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension
    Saadia Eddahibi
    INSERM U492 et Departement de Physiologie, Creteil, France
    Chest 121:97S-98S. 2002
  8. ncbi request reprint Angiopoietin/Tie2 pathway influences smooth muscle hyperplasia in idiopathic pulmonary hypertension
    Laurence Dewachter
    INSERM U651, Faculte de Medecine, 8, rue Général Sarrail, Creteil, France
    Am J Respir Crit Care Med 174:1025-33. 2006
  9. ncbi request reprint Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
    Christophe Guignabert
    INSERM U651, Departement de Physiologie, Hôpital H Mondor, AP HP, Creteil, France
    Circ Res 98:1323-30. 2006
  10. ncbi request reprint Serotonin transporter and receptors in various forms of human pulmonary hypertension
    Elisabeth Marcos
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Creteil, Paris, France
    Chest 128:552S-553S. 2005

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia
    Saadia Eddahibi
    INSERM U651, Departement de Physiologie, Hôpital H Mondor, AP HP, Creteil, France
    Circulation 113:1857-64. 2006
    ..We investigated the role of pulmonary microvascular endothelial cells (P-ECs) in controlling PA-SMC growth...
  2. pmc Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene
    Daniel Crona
    Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA
    BMC Pulm Med 9:19. 2009
    ..Previous studies have suggested effects on inflammation, proliferation, and vasoconstriction. The goal of this study was to determine which of these were supported by alterations in gene expression in serotonin transporter knockout mice...
  3. ncbi request reprint Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension
    Elisabeth Marcos
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, Creteil, France
    Circ Res 94:1263-70. 2004
    ..We conclude that 5-HTT overexpression is a common pathogenic mechanism in various forms of PH...
  4. ncbi request reprint Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease
    Saadia Eddahibi
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, AP HP, 94010 Creteil, France
    Circulation 108:1839-44. 2003
    ..Because hypoxia and 5-HTT gene polymorphism control 5-HTT expression, we examined 5-HTT gene polymorphism and PH in hypoxemic patients with advanced chronic obstructive pulmonary disease (COPD)...
  5. ncbi request reprint Role of endothelium-derived CC chemokine ligand 2 in idiopathic pulmonary arterial hypertension
    Olivier Sanchez
    INSERM U841 and Département de Physiologie Explorations Fonctionnelles, Hôpital H Mondor, AP HP, Creteil, France
    Am J Respir Crit Care Med 176:1041-7. 2007
    ..CC chemokine ligand 2 (CCL2) is synthesized by vascular cells and can stimulate monocyte/macrophage migration and smooth muscle cell (SMC) proliferation...
  6. pmc Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice
    William Raoul
    Unité INSERM TGU841 Université Paris XII, Creteil, France
    Respir Res 8:8. 2007
    ..Bone marrow -derived cells (BMDCs) can either limit or contribute to the process of pulmonary vascular remodeling. Whether the difference in their effects depends on the mechanism of pulmonary hypertension (PH) remains unknown...
  7. ncbi request reprint Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension
    Saadia Eddahibi
    INSERM U492 et Departement de Physiologie, Creteil, France
    Chest 121:97S-98S. 2002
  8. ncbi request reprint Angiopoietin/Tie2 pathway influences smooth muscle hyperplasia in idiopathic pulmonary hypertension
    Laurence Dewachter
    INSERM U651, Faculte de Medecine, 8, rue Général Sarrail, Creteil, France
    Am J Respir Crit Care Med 174:1025-33. 2006
    ..Angiopoietins are involved in blood vessel maturation and remodeling...
  9. ncbi request reprint Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
    Christophe Guignabert
    INSERM U651, Departement de Physiologie, Hôpital H Mondor, AP HP, Creteil, France
    Circ Res 98:1323-30. 2006
    ..They further support a central role for 5-HTT in the pathogenesis of PH, making 5-HTT a potential therapeutic target...
  10. ncbi request reprint Serotonin transporter and receptors in various forms of human pulmonary hypertension
    Elisabeth Marcos
    INSERM U492 and Service de Physiologie Explorations Fonctionnelles, Creteil, Paris, France
    Chest 128:552S-553S. 2005
  11. ncbi request reprint Interleukin-6 gene polymorphism confers susceptibility to pulmonary hypertension in chronic obstructive pulmonary disease
    Saadia Eddahibi
    INSERM U492 and Département de Physiologie, Hôpital H Mondor, Creteil, France
    Proc Am Thorac Soc 3:475-476. 2006
  12. ncbi request reprint Role of VEGF-B in the lung during development of chronic hypoxic pulmonary hypertension
    Vanessa Louzier
    Departement de Physiologie, Institut National de la Santé et de La Recherche Médicale Unité 492, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, 94010 Creteil, France
    Am J Physiol Lung Cell Mol Physiol 284:L926-37. 2003
    ..However, when overexpressed in the lung, VEGF-B can be as potent as VEGF-A in attenuating pulmonary hypertension, although it has no effect on eNOS expression or vascular permeability...
  13. ncbi request reprint Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats
    Christophe Guignabert
    Departement de Physiologie, INSERM U492, AP HP, CHU Henri Mondor, Creteil, France
    Circulation 111:2812-9. 2005
    ..Selective 5-HT(1B/1D), 5-HT(2A), and 5-HT(2B) receptor antagonists were used for comparative testing...
  14. ncbi request reprint Decrease in lung nitric oxide production after peritonitis in mice with sickle cell disease
    Pablo Bartolucci
    Unité INSERM U492 Université Paris XII, Creteil, and Laboratoire de Thérapie Génique Hématopoïétique, Hopital Saint Louis, Paris, France
    Crit Care Med 35:502-9. 2007
    ....
  15. doi request reprint Apoptosis and effects of intracavernous bone marrow cell injection in a rat model of postprostatectomy erectile dysfunction
    Papa Ahmed Fall
    Urology Department, Henri Mondor Teaching Hospital, Creteil, France
    Eur Urol 56:716-25. 2009
    ....
  16. ncbi request reprint Vascular-wall remodeling of 3 human bypass vessels: organ culture and smooth muscle cell properties
    Armand Mekontso-Dessap
    Institut National de la Sante et de la Recherche Medicale, Faculté de Médecine de Créteil, Creteil, France
    J Thorac Cardiovasc Surg 131:651-8. 2006
    ..The aim of the present study was to compare the vascular-wall remodeling of human internal thoracic artery, radial artery, and saphenous vein bypass conduits...
  17. pmc Anorexigen-induced pulmonary hypertension and the serotonin (5-HT) hypothesis: lessons for the future in pathogenesis
    Saadia Eddahibi
    INSERM U492, Departement de Physiologie, Hôpital H Mondor, Creteil, France
    Respir Res 3:9. 2002
    ....