Xavier Duval

Summary

Country: France

Publications

  1. pmc Amprenavir inhibitory quotient and virological response in human immunodeficiency virus-infected patients on an amprenavir-containing salvage regimen without or with ritonavir
    Xavier Duval
    Service des Maladies Infectieuses et Tropicales, Hopital Bichat Claude Bernard, Paris, France
    Antimicrob Agents Chemother 46:570-4. 2002
  2. doi request reprint Does enfuvirtide increase the risk of bacterial pneumonia in patients receiving combination antiretroviral therapy?
    I Kousignian
    INSERM U, Paris, France
    J Antimicrob Chemother 65:138-44. 2010
  3. doi request reprint Temporal trends in infective endocarditis in the context of prophylaxis guideline modifications: three successive population-based surveys
    Xavier Duval
    Inserm CIC 007, AP HP, Hôpital Universitaire Bichat, Paris, France
    J Am Coll Cardiol 59:1968-76. 2012
  4. pmc Flexibility of interval between vaccinations with AS03A-adjuvanted influenza A (H1N1) 2009 vaccine in adults aged 18-60 and >60 years: a randomized trial
    Xavier Duval
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, UMR 738, France
    BMC Infect Dis 12:162. 2012
  5. pmc Living with HIV, antiretroviral treatment experience and tobacco smoking: results from a multisite cross-sectional study
    Xavier Duval
    INSERM, Clinical Investigation Center 007, Inserm 738, Bichat, Paris, France
    Antivir Ther 13:389-97. 2008
  6. doi request reprint The new American Heart Association guidelines on the prevention of infective endocarditis: culmination of a long process of thought
    Xavier Duval
    Universite Paris 7, Denis Diderot, Paris, France
    Heart 94:715-6. 2008
  7. pmc Benefit of therapeutic drug monitoring of protease inhibitors in HIV-infected patients depends on PI used in HAART regimen--ANRS 111 trial
    Xavier Duval
    Inserm CIC 007, Hopital Bichat, Paris, France
    Fundam Clin Pharmacol 23:491-500. 2009
  8. doi request reprint [Prophylaxis of infective endocarditis: trends and new recommendations]
    X Duval
    Service des Maladies Infectieuses et Tropicales, Hopital Bichat Claude Bernard, 46, rue Henri Huchard, 75877 Paris Cedex 18, France
    Ann Cardiol Angeiol (Paris) 57:102-8. 2008
  9. doi request reprint Prophylaxis of infective endocarditis: current tendencies, continuing controversies
    Xavier Duval
    APHP, Department of Infectious and Tropical Diseases, Paris 7 Diderot University, Paris, France
    Lancet Infect Dis 8:225-32. 2008
  10. ncbi request reprint Estimated risk of endocarditis in adults with predisposing cardiac conditions undergoing dental procedures with or without antibiotic prophylaxis
    Xavier Duval
    Assistance Publique Hopitaux de Paris, Service des Maladies Infectieuses et Tropicales B, Centre Hospitalo Universitaire Bichat Claude Bernard, Universite Paris VII, INSERM U 738, Paris, France
    Clin Infect Dis 42:e102-7. 2006

Detail Information

Publications79

  1. pmc Amprenavir inhibitory quotient and virological response in human immunodeficiency virus-infected patients on an amprenavir-containing salvage regimen without or with ritonavir
    Xavier Duval
    Service des Maladies Infectieuses et Tropicales, Hopital Bichat Claude Bernard, Paris, France
    Antimicrob Agents Chemother 46:570-4. 2002
    ..03 to 0.70) and 7.0 (range, 1.4 to 145), respectively. At week 24, 2 of 8 and 13 of 14 patients in groups A and B, respectively, had <200 HIV RNA copies/ml of plasma, including 4 of 5 patients infected with APV-resistant viruses...
  2. doi request reprint Does enfuvirtide increase the risk of bacterial pneumonia in patients receiving combination antiretroviral therapy?
    I Kousignian
    INSERM U, Paris, France
    J Antimicrob Chemother 65:138-44. 2010
    ....
  3. doi request reprint Temporal trends in infective endocarditis in the context of prophylaxis guideline modifications: three successive population-based surveys
    Xavier Duval
    Inserm CIC 007, AP HP, Hôpital Universitaire Bichat, Paris, France
    J Am Coll Cardiol 59:1968-76. 2012
    ..The goal of this study was to evaluate temporal trends in infective endocarditis (IE) incidence and clinical characteristics after 2002 French IE prophylaxis guideline modifications...
  4. pmc Flexibility of interval between vaccinations with AS03A-adjuvanted influenza A (H1N1) 2009 vaccine in adults aged 18-60 and >60 years: a randomized trial
    Xavier Duval
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, UMR 738, France
    BMC Infect Dis 12:162. 2012
    ....
  5. pmc Living with HIV, antiretroviral treatment experience and tobacco smoking: results from a multisite cross-sectional study
    Xavier Duval
    INSERM, Clinical Investigation Center 007, Inserm 738, Bichat, Paris, France
    Antivir Ther 13:389-97. 2008
    ..To assess the prevalence of and factors associated with tobacco smoking and dependence in HIV patients...
  6. doi request reprint The new American Heart Association guidelines on the prevention of infective endocarditis: culmination of a long process of thought
    Xavier Duval
    Universite Paris 7, Denis Diderot, Paris, France
    Heart 94:715-6. 2008
  7. pmc Benefit of therapeutic drug monitoring of protease inhibitors in HIV-infected patients depends on PI used in HAART regimen--ANRS 111 trial
    Xavier Duval
    Inserm CIC 007, Hopital Bichat, Paris, France
    Fundam Clin Pharmacol 23:491-500. 2009
    ....
  8. doi request reprint [Prophylaxis of infective endocarditis: trends and new recommendations]
    X Duval
    Service des Maladies Infectieuses et Tropicales, Hopital Bichat Claude Bernard, 46, rue Henri Huchard, 75877 Paris Cedex 18, France
    Ann Cardiol Angeiol (Paris) 57:102-8. 2008
    ..Systematic antibiotic prophylaxis remains necessary, however, in the category of patients at very high risk...
  9. doi request reprint Prophylaxis of infective endocarditis: current tendencies, continuing controversies
    Xavier Duval
    APHP, Department of Infectious and Tropical Diseases, Paris 7 Diderot University, Paris, France
    Lancet Infect Dis 8:225-32. 2008
    ..Recommendations for prophylaxis are now essentially focused on patients with high-risk predisposing cardiac conditions before dental procedures...
  10. ncbi request reprint Estimated risk of endocarditis in adults with predisposing cardiac conditions undergoing dental procedures with or without antibiotic prophylaxis
    Xavier Duval
    Assistance Publique Hopitaux de Paris, Service des Maladies Infectieuses et Tropicales B, Centre Hospitalo Universitaire Bichat Claude Bernard, Universite Paris VII, INSERM U 738, Paris, France
    Clin Infect Dis 42:e102-7. 2006
    ....
  11. ncbi request reprint Diabetes mellitus and infective endocarditis: the insulin factor in patient morbidity and mortality
    Xavier Duval
    Universite Paris 7, Denis Diderot, Laboratoire de pathologie Infectieuse, Paris, France
    Eur Heart J 28:59-64. 2007
    ..To analyse the characteristics of infective endocarditis (IE) in patients with diabetes mellitus (DM), and to evaluate the prognostic significance of DM according to insulin use...
  12. ncbi request reprint [Analyzing clinical trials: subgroup, stratified, and intermediate analyses, and composite outcome criteria]
    Xavier Duval
    centre d investigation clinique, Hopital Bichat Claude Bernard, Paris
    Presse Med 36:519-23. 2007
    ..Composite outcome criteria combine several different elements, all of which must be clinically relevant. Unequal treatments effects on the various criteria may complicate interpretation of the results...
  13. doi request reprint Effect of early cerebral magnetic resonance imaging on clinical decisions in infective endocarditis: a prospective study
    Xavier Duval
    Paris 7 University Medical School, AP HP Bichat University Hospital, and INSERM CIC 007, Paris, France
    Ann Intern Med 152:497-504, W175. 2010
    ..Neurologic complications of endocarditis can influence diagnosis, therapeutic plans, and prognosis...
  14. pmc Influence of pharmacogenetics on indinavir disposition and short-term response in HIV patients initiating HAART
    Julie Bertrand
    UMR 738, INSERM, Universite Paris Diderot, UFR de Medecine, 16, rue Henri Huchard, 75018, Paris, France
    Eur J Clin Pharmacol 65:667-78. 2009
    ..To assess the relationship between genetic polymorphisms and indinavir pharmacokinetic variability and to study the link between concentrations and short-term response or metabolic safety...
  15. doi request reprint Prognostic value of B-type natriuretic peptide in elderly patients with aortic valve stenosis: the COFRASA-GENERAC study
    Claire Cimadevilla
    Department of Cardiology, Assistance Publique Hopitaux de Paris, Bichat Hospital, Paris, France
    Heart 99:461-7. 2013
    ..We aimed to evaluate the relationship among N-terminal fragment of proBNP (Nt-proBNP), AS severity, symptoms and outcome in a large cohort of elderly patients with AS...
  16. ncbi request reprint Lamivudine and indinavir/ritonavir maintenance therapy in highly pretreated HIV-infected patients (Vista ANRS 109)
    Odile Launay
    Faculte de Medecine, Universite Paris Descartes, Service de Medecine Interne, Hopital Cochin, AP HP, Paris, France
    Antivir Ther 11:889-99. 2006
    ..We hypothesized that this delay period could be based on a simplified treatment, which would reduce drug toxicity, stabilize resistance, and prevent resurgence of wild-type virus...
  17. doi request reprint Determinants of cerebral lesions in endocarditis on systematic cerebral magnetic resonance imaging: a prospective study
    Bernard Iung
    From the Departments of Cardiology B I, D M Z, E B, Biostatistic S T, Radiology I K, Cardiovascular Surgery L L, N A A, Microbiology R R, Intensive Care M W, and Infectious Disease X D, AP HP, Bichat Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, France B I, R R, C L, M W, X D INSERM Clinical Investigation Center 007, Paris, France S T, X D and INSERM U738, Paris, France C L, X D
    Stroke 44:3056-62. 2013
    ..However, their determinants have not been identified. The aim of the study was to define the determinants of cerebral lesions in patients with IE undergoing systematic cerebral MRI...
  18. ncbi request reprint How do HIV-infected smokers react to cigarette price increases? Evidence from the APROCO-COPILOTE-ANRS CO8 Cohort
    Patrick Peretti-Watel
    INSERM, U912 SE4S, Marseille, France
    Curr HIV Res 7:462-7. 2009
    ..Raising cigarette prices is usually considered as one of the most effective ways to reduce smoking, but its effectiveness has never been studied among HIV-infected smokers...
  19. ncbi request reprint High variability of indinavir and nelfinavir pharmacokinetics in HIV-infected patients with a sustained virological response on highly active antiretroviral therapy
    Cecile Goujard
    Internal Medicine Unit, Bicetre University Hospital, AP HP, Kremlin Bicetre, France
    Clin Pharmacokinet 44:1267-78. 2005
    ....
  20. ncbi request reprint Indinavir plasma concentration and adherence score are codeterminant of early virologic response in HIV-infected patients of the APROCO cohort
    Xavier Duval
    Laboratoire de Recherche en Pathologie Infectieuse, Faculte Xavier Bichat, Paris, France
    Ther Drug Monit 27:63-70. 2005
    ..These data suggest that any strategy of therapeutic drug monitoring must imply first a combined evaluation of plasma concentrations and adherence level and second an intervention target based on the results of both assessments...
  21. ncbi request reprint Indinavir trough concentration as a determinant of early nephrolithiasis in HIV-1-infected adults
    Fideline Collin
    INSERM, U593, Bordeaux, France, and ISPED, Universite Victor Segalen Bordeaux 2, ISPED Bordeaux, France
    Ther Drug Monit 29:164-70. 2007
    ..Prospective and early indinavir Cres determination should be recommended in the patient's care management and dosage adjustments...
  22. doi request reprint Systematic evaluation and description of anal pathology in HIV-infected patients during the HAART era
    Laurent Abramowitz
    AP HP, Department of Gastroenterology and Proctology, Bichat University Hospital, Paris, France
    Dis Colon Rectum 52:1130-6. 2009
    ..This study aimed to determine the prevalence of macroscopic anal lesions and associated factors in HIV-infected outpatients during the era of highly active antiretroviral therapy...
  23. ncbi request reprint Hair versus plasma concentrations as indicator of indinavir exposure in HIV-1-infected patients treated with indinavir/ritonavir combination
    Xavier Duval
    Services des Maladies Infectieuses et Tropicales, Biostatistique et Recherche Clinique, Paris, France
    AIDS 21:106-8. 2007
    ....
  24. ncbi request reprint Clinical and immunologic outcome in patients with human immunodeficiency virus infection, according to virologic efficacy in the year after virus undetectability, during antiretroviral therapy
    Sophie Abgrall
    Equipe mixte INSERM 0214, Hopital Pitie Salpetriere, Paris, France
    Clin Infect Dis 37:1517-26. 2003
    ..18 [95% CI, 0.48-2.92]; aHR for immunologic failure, 1.07 [95% CI, 0.87-1.32]), suggesting that a low viral rebound while receiving HAART that contains a PI has no significant consequence on midterm clinical outcome...
  25. pmc Adherence profiles and therapeutic responses of treatment-naive HIV-infected patients starting boosted atazanavir-based therapy in the ANRS 134-COPHAR 3 trial
    Jean Jacques Parienti
    Univ Paris Diderot, Sorbonne Paris Cité, UMR 738, and INSERM, UMR 738, Paris, France
    Antimicrob Agents Chemother 57:2265-71. 2013
    ..Timing compliance should be supported to optimize DVS during the early phase of treatment by once-daily boosted protease inhibitor-based ART. (This study has been registered at ClinicalTrials.gov under registration no. NCT00528060.)...
  26. pmc Effect of CYP2C19 polymorphism on nelfinavir to M8 biotransformation in HIV patients
    Deborah Hirt
    Service de Pharmacologie Clinique, AP HP, Hopital Cochin Saint Vincent de Paul, Universite Paris Descartes, Paris, France
    Br J Clin Pharmacol 65:548-57. 2008
    ..However, for MDR1 and CYP2C19 polymorphism, there have been contradictory studies, showing either no impact on nelfinavir concentration or modified concentrations which could influence virological response...
  27. doi request reprint Role of radiolabelled leucocyte scintigraphy in patients with a suspicion of prosthetic valve endocarditis and inconclusive echocardiography
    Fabien Hyafil
    Department of Nuclear Medicine, Inserm U698 Cardiovascular Bioengineering, Bichat University Hospital, Assistance Publique Hopitaux de Paris, University Paris Diderot Paris 7, 46 rue Henri Huchard, 75018 Paris, France
    Eur Heart J Cardiovasc Imaging 14:586-94. 2013
    ....
  28. ncbi request reprint CD4+ T-cell percentage is an independent predictor of clinical progression in AIDS-free antiretroviral-naive patients with CD4+ T-cell counts >200 cells/mm3
    Marguerite Guiguet
    INSERM U943, Paris, France
    Antivir Ther 14:451-7. 2009
    ....
  29. pmc Evolution of human immunodeficiency virus type 1 (HIV-1) resistance mutations in nonnucleoside reverse transcriptase inhibitors (NNRTIs) in HIV-1-infected patients switched to antiretroviral therapy without NNRTIs
    Veronique Joly
    Service des Maladies Infectieuses et Tropicales A, Hopital Bichat Claude Bernard, 75877 Paris Cedex 18, France
    Antimicrob Agents Chemother 48:172-5. 2004
    ..These results argue for the low impact of NNRTI resistance mutations on viral fitness and suggest that resistance mutations to different classes of drugs are associated on the same genome, at least in some of the resistant strains...
  30. pmc Host factors and portal of entry outweigh bacterial determinants to predict the severity of Escherichia coli bacteremia
    Agnes Lefort
    AP HP, Hopital Beaujon, Service de Medecine Interne, 92110 Clichy Cedex, France
    J Clin Microbiol 49:777-83. 2011
    ..46 [95% CI, 0.30 to 0.70] and OR = 0.53 [95% CI, 0.30 to 0.91], respectively). In summary, host factors and the portal of entry outweigh bacterial determinants for predicting E. coli bacteremia severity...
  31. doi request reprint Progression of aortic valve stenosis is associated with bone remodelling and secondary hyperparathyroidism in elderly patients--the COFRASA study
    Guillaume Hekimian
    Cardiovascular Division, Department of Cardiology, AP HP, Bichat Hospital, Paris, France
    Eur Heart J 34:1915-22. 2013
    ..There is currently no medical therapy that can prevent the progression of aortic valve stenosis (AS). Recent data highlight a possible relationship between bone metabolism and AS progression but prospective data are lacking...
  32. ncbi request reprint Anal squamous intraepithelial lesions and condyloma in HIV-infected heterosexual men, homosexual men and women: prevalence and associated factors
    Laurent Abramowitz
    Department of Gastroenterology and Proctology, Bichat Hospital, Paris, France
    AIDS 21:1457-65. 2007
    ..To assess the prevalence of and factors associated with squamous intraepithelial lesions and condyloma [human papillomavirus (HPV)-related lesions) in HIV-infected patients...
  33. doi request reprint Respective effects of early cerebral and abdominal magnetic resonance imaging on clinical decisions in infective endocarditis
    Bernard Iung
    AP HP, Department of Cardiology, Bichat University Hospital, and Paris Diderot Paris 7 University Medical School, Paris, France
    Eur Heart J Cardiovasc Imaging 13:703-10. 2012
    ..The aim of this study was to assess how early combined cerebral and abdominal magnetic resonance imaging (MRI) affects the diagnosis and management of adults with endocarditis...
  34. ncbi request reprint Impact of newly available drugs on clinical progression in patients with virological failure after exposure to three classes of antiretrovirals
    Dominique Costagliola
    INSERM U720, Universite Pierre et Marie Curie, Paris, France
    Antivir Ther 10:563-73. 2005
    ..To study the prognosis of HIV-infected patients with virological failure after exposure to three classes of antiretroviral drugs (ARVs)...
  35. pmc Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss
    Elisabeth Dam
    INSERM U552, Paris, France
    PLoS Pathog 5:e1000345. 2009
    ..Further compensatory mutations render viral RC independent of the A431V or I437V mutations while their effect on resistance persists...
  36. ncbi request reprint Tubulopathy consecutive to tenofovir-containing antiretroviral therapy in two patients infected with human immunodeficiency virus-1
    Guillaume Breton
    Department of Infectious and Tropical Diseases, Bichat Claude Bernard Hospital, Paris, France
    Scand J Infect Dis 36:527-8. 2004
    ..The risk of renal tubulopathy symptoms in patients on long-term tenofovir therapy should be noted...
  37. pmc Predominant role of host proteases in myocardial damage associated with infectious endocarditis induced by Enterococcus faecalis in a rat model
    Pascal Augustin
    Inserm UMR698, Paris, France
    Infect Immun 81:1721-9. 2013
    ..Our results suggest that, despite the lack of bacterial proteases, the continuous attractant signals coming from bacterial colonies may lead to a chronic and deleterious aggression toward myocardial/valvular tissues by host proteases...
  38. ncbi request reprint Effect of oseltamivir, zanamivir or oseltamivir-zanamivir combination treatments on transmission of influenza in households
    Fabrice Carrat
    APHP, Hopital Saint Antoine, Unité de santé publique, Paris, France
    Antivir Ther 17:1085-90. 2012
    ..The effectiveness of neuraminidase inhibitors to reduce transmission when used as treatment in influenza-infected patients remains debated...
  39. doi request reprint Preoperative use and safety of coronary angiography for acute aortic valve infective endocarditis
    Guillaume Hekimian
    Cardiology Department, APHP and University Paris, Bichat Hospital, Paris, France
    Heart 96:696-700. 2010
    ....
  40. ncbi request reprint Maintenance therapy with cotrimoxazole for toxoplasmic encephalitis in the era of highly active antiretroviral therapy
    Xavier Duval
    Department of Infectious Diseases, Bichat Claude Bernard Hospital, Paris, France
    AIDS 18:1342-4. 2004
    ..1 cases per 100 patient-years (95% confidence interval, 0.05-11.3). This strategy could be useful for patients awaiting immune reconstitution which allows the interruption of TE maintenance therapy...
  41. ncbi request reprint Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus
    Francine Walker
    Department of Pathology, Institut de la Santé et de la Recherche Médicale Unité773, Hopital Bichat Claude Bernard, 75018 Paris, France
    Hum Pathol 40:1517-27. 2009
    ..The finding that EGFR, c-Met, and VEGFR1 involved in carcinogenesis are well-represented and coexpressed in anal cancers, especially in HIV-positive population, suggests possible novel targeted treatments for anal diseases...
  42. ncbi request reprint Determinants of immune reconstitution inflammatory syndrome in HIV type 1-infected patients with tuberculosis after initiation of antiretroviral therapy
    Guillaume Breton
    Department of Infectious and Tropical Diseases, INSERM E0357, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Clin Infect Dis 39:1709-12. 2004
    ..These results have implications for the diagnosis of IRIS and the understanding of its pathogenesis...
  43. ncbi request reprint Mechanisms involved in the low-level regeneration of CD4+ cells in HIV-1-infected patients receiving highly active antiretroviral therapy who have prolonged undetectable plasma viral loads
    Olivier Benveniste
    Service de Medecine Interne, Hopital Pitie Salpetriere, Paris, France
    J Infect Dis 191:1670-9. 2005
    ..Persistent low CD4(+) cell counts are observed in 5%-27% of patients treated for human immunodeficiency virus (HIV)-1 infection despite their having prolonged undetectable plasma viral loads...
  44. doi request reprint Bacteraemia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features
    A Courpon-Claudinon
    AP HP, Hopital Louis Mourier, Service de Microbiologie Hygiène, Colombes, France
    Clin Microbiol Infect 17:557-65. 2011
    ..The fact that the molecular support of 3GC resistance is mainly plasmid-mediated represents a potentially epidemic threat...
  45. doi request reprint Unusual presentation of cryolife O'Brien(R) stentless aortic valve bioprosthesis dysfunction mimicking infective endocarditis
    Laurent Lepage
    Department of Cardiac Surgery, AP HP, Bichat Hospital, Paris, France
    Eur J Cardiothorac Surg 41:800-5. 2012
    ..We reviewed all cases of aortic PV-IE admitted in our institution and compared the clinical presentation, bacteriological and echocardiographic features according to the type of prosthesis...
  46. ncbi request reprint Brief report: prevalence of antineutrophil cytoplasmic antibodies in infective endocarditis
    Alfred Mahr
    Hopital St Louis, AP HP, and Université Paris Diderot, Paris 7, Paris, France
    Arthritis Rheumatol 66:1672-7. 2014
    ..Because the frequency of ANCAs in IE is unknown, this study was undertaken to assess the seroprevalence of ANCAs in a large number of patients with IE...
  47. pmc Role of vegetation-associated protease activity in valve destruction in human infective endocarditis
    Ghada Al-Salih
    INSERM U698, Paris, France
    PLoS ONE 7:e45695. 2012
    ..We hypothesized that host defense activation may be directly involved in tissue proteolytic aggression, in addition to pathogenic effects of bacterial colonization...
  48. ncbi request reprint Incidence of and risk factors for adverse drug reactions in a prospective cohort of HIV-infected adults initiating protease inhibitor-containing therapy
    Xavier Duval
    Laboratoire de Recherche en Pathologie Infectieuse, Faculte Xavier Bichat, Paris, France
    Clin Infect Dis 39:248-55. 2004
    ..7; 95% CI, 1.2-2.4) were independently predictive of a SADR. SADRs were frequent in the first 4 months after initiation of highly active antiretroviral therapy but continued to occur after that time period...
  49. pmc Ciprofloxacin dosage and emergence of resistance in human commensal bacteria
    Bruno Fantin
    Universite Paris Diderot, Paris, France
    J Infect Dis 200:390-8. 2009
    ..Although optimization of the fluoroquinolone dosage increases the efficacy of this class of drugs against bacterial infections, its impact on the emergence of resistance in commensal bacteria is unknown...
  50. ncbi request reprint Modeling the time course of CD4 T-lymphocyte counts according to the level of virologic rebound in HIV-1-infected patients on highly active antiretroviral therapy
    Isabelle Kousignian
    INSERM EMI 0214, Paris, France
    J Acquir Immune Defic Syndr 34:50-7. 2003
    ..To study the influence of the level of virologic rebound during combination antiretroviral therapy on the time course of the CD4 count...
  51. pmc Hot spots of integrase genotypic changes leading to HIV-2 resistance to raltegravir
    Charlotte Charpentier
    Hopital Bichat Claude Bernard, Laboratoire de Virologie, 46 rue Henri Huchard, 75018 Paris, France
    Antimicrob Agents Chemother 55:1293-5. 2011
    ..Thus, despite a 40% difference in integrase genes between HIV-1 and HIV-2, the genetic pathways leading to raltegravir resistance are similar...
  52. doi request reprint Cerebral microbleeds are frequent in infective endocarditis: a case-control study
    Isabelle Klein
    Department of Radiology, Bichat University Hospital, 75018 Paris, France
    Stroke 40:3461-5. 2009
    ..CMBs have been reported in isolated cases of infective endocarditis (IE), but their frequency and the association of CMBs with IE have not yet been studied...
  53. pmc Is long-term virological response related to CCR5 Delta32 deletion in HIV-1-infected patients started on highly active antiretroviral therapy?
    J J Laurichesse
    Laboratoire de Recherche en Pathologie Infectieuse, Universite Paris 7, Paris, France
    HIV Med 11:239-44. 2010
    ..The aim of the study was to determine whether the chemokine (C-C motif) receptor 5 (CCR5) Delta32 deletion is associated with long-term response to combination antiretroviral treatment (cART) in HIV-1-infected patients...
  54. ncbi request reprint Silent T2* cerebral microbleeds: a potential new imaging clue in infective endocarditis
    I Klein
    Department of Radiology, Bichat University Hospital, Paris, France
    Neurology 68:2043. 2007
  55. ncbi request reprint Determination of indinavir and nelfinavir trough plasma concentration efficacy thresholds according to virological response in HIV-infected patients
    X Duval
    Infectious and Tropical Diseases, Bichat Claude Bernard Hospital, Paris, France
    HIV Med 5:307-13. 2004
    ....
  56. doi request reprint Informed consent in clinical research in France: assessment and factors associated with therapeutic misconception
    I S Durand-Zaleski
    AP HP, Henri Mondor Hospital, Public Health, Creteil, France
    J Med Ethics 34:e16. 2008
    ..Informed consent in clinical research is mandated throughout the world. Both patient subjects and investigators are required to understand and accept the distinction between research and treatment...
  57. doi request reprint Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy
    Christophe Piketty
    AP HP, Department of Clinical Immunology, Georges Pompidou European Hospital, Rene Descartes University, Paris, France
    AIDS 22:1203-11. 2008
    ..To describe the cases of anal cancer that appeared in the French Hospital Database on HIV between 1992 and 2004 and to study risk factors of anal cancer...
  58. doi request reprint HIV-1 DNA for the measurement of the HIV reservoir is predictive of disease progression in seroconverters whatever the mode of result expression is
    Véronique Avettand-Fenoel
    AP HP, CHU Necker Enfants Malades, Laboratoire de Virologie, Paris, France
    J Clin Virol 42:399-404. 2008
    ..Previously, HIV-DNA levels have sometimes been reported by other means: copies/10(6) CD4(+)T cells, reflecting the proportion of infected cells; or copies/mL whole blood, reflecting the global blood reservoir size...
  59. pmc 2011-12 seasonal influenza vaccines effectiveness against confirmed A(H3N2) influenza hospitalisation: pooled analysis from a European network of hospitals. A pilot study
    Marc Rondy
    EpiConcept, Paris, France
    PLoS ONE 8:e59681. 2013
    ..We assessed the feasibility of measuring seasonal IVE against hospitalisation with laboratory confirmed influenza through a network of 21 hospitals in the European Union...
  60. ncbi request reprint Endocarditis in patients with a permanent pacemaker: a 1-year epidemiological survey on infective endocarditis due to valvular and/or pacemaker infection
    Xavier Duval
    University Medical Center of Bichat Claude Bernard, Assistance Publique Hôpital de Paris, Paris, France
    Clin Infect Dis 39:68-74. 2004
    ..The incidence of age- and sex-standardized IE was 550 cases/million PM recipients per year. The incidence of IE with PM involvement is between that of valvular IE in the general population and prosthetic valve IE...
  61. doi request reprint Measurement of aortic valve calcification using multislice computed tomography: correlation with haemodynamic severity of aortic stenosis and clinical implication for patients with low ejection fraction
    Caroline Cueff
    Cardiology Department, AP HP, Bichat Hospital, Paris, France
    Heart 97:721-6. 2011
    ..Whether threshold values of AVC obtained with EBCT could be extrapolated to multislice computed tomography (MSCT) was unclear and AVC diagnostic value in patients with low ejection fraction (EF) has never been specifically evaluated...
  62. doi request reprint Causes of the first AIDS-defining illness and subsequent survival before and after the advent of combined antiretroviral therapy
    S Grabar
    Department of Public Health, Cochin Hospital, Paris, France
    HIV Med 9:246-56. 2008
    ....
  63. pmc Extended antigen sparing potential of AS03-adjuvanted pandemic H1N1 vaccines in children, and immunological equivalence of two formulations of AS03-adjuvanted H1N1 vaccines: results from two randomised trials
    Odile Launay
    INSERM, CIC BT505 Assistance Publique Hôpitaux de Paris, Groupe Hospitalier Cochin Broca Hôtel Dieu, CIC de vaccinologie Cochin Pasteur Université Paris Descartes, Paris, France
    BMC Infect Dis 13:435. 2013
    ..We evaluated equivalence in terms of immunogenicity between GlaxoSmithKline Vaccines' A/California/7/2009 (H1N1)v-like-AS03 vaccines manufactured in Dresden (D-Pan), and Quebec (Q-Pan)...
  64. doi request reprint Preventive services recommendations for adults in primary care settings: agreement between Canada, France and the USA--a systematic review
    Julien Gelly
    Univ Paris Diderot, Sorbonne Paris Cité, Dept of General Practice, F 75018, Paris, France
    Prev Med 57:3-11. 2013
    ..To analyze the level of agreement between recommendations on preventive services developed by Canada, France and the USA...
  65. doi request reprint Technetium 99m-labeled annexin V scintigraphy of platelet activation in vegetations of experimental endocarditis
    Francois Rouzet
    AP HP, Groupe Hospitalier Bichat Claude Bernard, Service de Medecine Nucleaire, Paris, France
    Circulation 117:781-9. 2008
    ..This ability was assessed in rabbits and rats because of the different interest of these 2 species in preclinical analysis...
  66. doi request reprint Factors associated with non-adherence to long-term highly active antiretroviral therapy: a 10 year follow-up analysis with correction for the bias induced by missing data
    Camelia Protopopescu
    INSERM, U912 SE4S, 13006 Marseille, France
    J Antimicrob Chemother 64:599-606. 2009
    ..The aim of this study was to identify factors associated with non-adherence over a 10 year follow-up of the APROCO-COPILOTE cohort during the maintenance phase of highly active antiretroviral therapy (HAART)...
  67. ncbi request reprint [Long-term immunologic response in HIV-infected patients with CD4 cell counts </= 50/mm3 when initiating protease inhibitor therapy]
    V Le Moing
    Service des Maladies Infectieuses et Tropicales, , Paris
    Ann Med Interne (Paris) 152:11-4. 2001
    ..This immunological response was correlated with the duration of the virological response. However, 38% of patients with long-term immunological response never had a undetectable viral load...
  68. doi request reprint Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin
    Eve Maubec
    Hopital Bichat, Service de Dermatologie, 46 rue Henri Huchard, Paris, cedex 75877, France
    J Clin Oncol 29:3419-26. 2011
    ..To evaluate the efficacy and safety of cetuximab, a monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), as a first-line monotherapy in patients with unresectable squamous cell carcinoma of the skin (SCCS)...
  69. pmc Cryptococcal neuroradiological lesions correlate with severity during cryptococcal meningoencephalitis in HIV-positive patients in the HAART era
    Caroline Charlier
    Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA 3012, Institut Pasteur, Paris, France
    PLoS ONE 3:e1950. 2008
    ..Given this, we suggest that investigation for cryptococcosis-related lesions is merited, even in the absence of neurological abnormality, if a high fungal burden is suspected on the basis of high serum and/or CSF antigen titers...
  70. ncbi request reprint [Paradoxical aggravation of tuberculosis after antiretroviral therapy in HIV-infected patients]
    X Duval
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Bichat-Claude Bernard, 46, rue Henri Huchard, F75877 Paris
    Presse Med 30:213-6. 2001
    ..The onset of antiretroviral therapy could thus be delayed by several weeks in HIV-infected patients treated for active tuberculosis and who have never received antiretroviral therapy...
  71. doi request reprint How does loss to follow-up influence cohort findings on HIV infection? A joint analysis of the French hospital database on HIV, Mortalité 2000 survey and death certificates
    E Lanoy
    INSERM, U720, Paris, France
    HIV Med 10:236-45. 2009
    ....
  72. ncbi request reprint Salivary cytomegalovirus (CMV) shedding, glycoprotein B genotype distribution, and CMV disease in human immunodeficiency virus-seropositive patients
    N Fidouh-Houhou
    Department of Virology, Bichat-Claude Bernard Hospital, Paris, France
    Clin Infect Dis 33:1406-11. 2001
    ..CMV salivary shedding (P=.043), low CD4+ cell count (P=.041), and CMV viremia (P=.011) were associated with occurrence of CMV disease...
  73. ncbi request reprint Failure of valacyclovir for herpes zoster in a moderately immunocompromised HIV-infected patient
    G Breton
    Department of Infectious and Tropical Diseases Bichat Claude Bernard Hospital, Paris, France
    AIDS Patient Care STDS 18:255-7. 2004
    ..Clinical outcome was favorable after intravenous acyclovir. This case suggests careful monitoring of valacyclovir in HIV-infected patients is necessary...
  74. ncbi request reprint Definite streptococcus bovis endocarditis: characteristics in 20 patients
    X Duval
    Service des Maladies Infectieuses et Tropicales, and Service de Bacteriologie, , Paris, France
    Clin Microbiol Infect 7:3-10. 2001
    ..bovis IE observed in this study...
  75. ncbi request reprint [What is the state of infective endocarditis prophylaxis guidelines according to the latest American recommendations?]
    X Duval
    centre d investigation clinique, INSERM 007, Laboratoire de Recherche en Pathologie Infectieuse, Universite Paris 7, CHU Bichat Claude Bernard, université Paris VII Denis Diderot, 46 rue Henri Huchard, Paris Cedex 18, France
    Med Mal Infect 38:S52-4. 2008
  76. ncbi request reprint Evolution of protease and reverse transcriptase inhibitor resistance-associated mutations in HIV-1-infected protease inhibitor-treated patients with persistent low viraemia
    Xavier Duval
    Antivir Ther 10:197-9. 2005
  77. ncbi request reprint Retroviral rebound syndrome with meningoencephalitis after cessation of antiretroviral therapy
    Guillaume Breton
    Am J Med 114:769-70. 2003
  78. ncbi request reprint Is phosphatemia the best tool to monitor renal tenofovir toxicity?
    Marie Essig
    J Acquir Immune Defic Syndr 46:256-8. 2007
  79. ncbi request reprint Development of an assay method for the detection and quantification of protease and non-nucleoside reverse transcriptase inhibitors in plasma and in peripherical blood mononuclear cells by liquid chromatography coupled with ultraviolet or tandem mass spec
    Hélène Pélerin
    CEA, Service de Pharmacologie et d Immunologie, DSV DRM, 91191 Gif sur Yvette Cedex, France
    J Chromatogr B Analyt Technol Biomed Life Sci 819:47-57. 2005
    ..25 to 250 ng/pellet. Simple modifications in the mobile phase composition (slight increase of ammonium acetate concentration and addition of methanol for LC-UV) easily linked the two analytical systems...